ライフサイエンスコーパス: Neurospora

1 le for RIC8 in regulating GNA-1 and GNA-3 in Neurospora.

2 tly different from what has been observed in Neurospora.

3 light-regulated transcriptional responses in Neurospora.

4 served in other organisms were identified in Neurospora.

5 ylation sites in core histones isolated from Neurospora.

6 equences for targeting to the his-3 locus in Neurospora.

7 PROTEIN 1 (HP1) and associated proteins from Neurospora.

8 dian- and light-regulated gene expression in Neurospora.

9 ated genes are also dsRNA-activated genes in Neurospora.

10 e and prevents Vivid from sending signals in Neurospora.

11 the polypyrimidine tract, is also present in Neurospora.

12 ich underlies circadian rhythm generation in Neurospora.

13 ortant role of CSN in the circadian clock of Neurospora.

14 ssential DEAD box-containing RNA helicase in Neurospora.

15 were studied in the filamentous fungal genus Neurospora.

16 ies of the gene in the diploid ascus cell of Neurospora.

17 rom Period in mammals and frequency (frq) in Neurospora.

18 g codon usage bias in the filamentous fungus Neurospora.

19 is required for circadian clock function in Neurospora.

20 ologically relevant arabinose transporter in Neurospora.

21 result in synchronized nuclear divisions in Neurospora.

22 d phenomenon from repetitive genomic loci in Neurospora.

23 y silences repetitive DNA and transposons in Neurospora.

24 in rRecQ1, which is homologous to qde-3 from Neurospora, a gene implicated in silencing pathways.

25 We adapted the Cre/loxP system for Neurospora, allowing the selectable marker hph to be exc

26 inery and experimental validations employing Neurospora and brings a deeper understanding of molecula

27 Overall our data indicate that Neurospora and higher eukaryotes share a common mechanis

28 e the most studied meiotic drive elements in Neurospora, and they each theoretically contain two esse

29 pretation of ongoing experimental efforts in Neurospora, and we anticipate that our methods will subs

30 by analyzing small RNAs associated with the Neurospora Argonaute protein QDE-2, we show that diverse

31 component of the chromosome conformation in Neurospora, but two widely studied key heterochromatin p

32 genetics experiments originally performed on Neurospora by comprehensively predicting nutrient rescue

33 Here we used a Neurospora cell-free translation system to directly moni

34 d mammalian centromeres, was not enriched in Neurospora centromeric DNA.

35 nown to bind H3K4me3 in mammalian cells, and Neurospora CHD1 is required for proper regulation of the

36 Thus, prd-4, the Neurospora Chk2, identifies a molecular link that feeds

37 the telomere regions of other organisms, the Neurospora chromosome termini still retain the dynamic n

38 stimuli that activate the expression of the Neurospora circadian clock gene frequency (frq), can tri

39 re-based codon manipulation of codons in the Neurospora circadian clock gene frequency (frq).

40 , we constructed a mathematical model of the Neurospora circadian clock incorporating the above WC-1/

41 Ubiquitination-mediated degradation of the Neurospora circadian clock protein FREQUENCY (FRQ) is cr

42 Phosphorylation of the Neurospora circadian clock protein FREQUENCY by several

43 In the Neurospora circadian clock, the PER-ARNT-SIM (PAS) domai

44 QUENCY (FRQ) is the central component of the Neurospora circadian clock.

45 oop and is important for the function of the Neurospora circadian clock.

46 exerts significant metabolic control on the Neurospora circadian clock.

47 In the Neurospora circadian negative feedback loop, FREQUENCY (

48 In the Neurospora circadian negative feedback loop, FRQ and FRH

49 The Neurospora circadian oscillator comprises FREQUENCY (FRQ

50 In the Neurospora circadian oscillator, the transcription of th

51 dicating that FRQ is a state variable of the Neurospora circadian oscillator.

52 es similar components and circuitry with the Neurospora circadian system, although we found that its

53 In the Neurospora circadian system, the transcription factors W

54 In the Neurospora circadian system, the White Collar complex (W

55 Altogether, our findings with Neurospora clarify interactions of facultative and const

56 regulator of temperature compensation of the Neurospora clock by determining that two long-standing c

57 in phosphatase 4 is a novel component of the Neurospora clock by regulating both processes of the cir

58 frequency (frq) encodes a component of the Neurospora core circadian negative feedback loop, which

59 Like PERIOD in animals, the Neurospora core circadian protein FRQ is progressively p

60 g the motility of a fast fungal kinesin from Neurospora crassa (NcKin).

61 is study, we have characterized an LPMO from Neurospora crassa (NcLPMO9C; also known as NCU02916 and

62 he deprotonation of nitroethane catalyzed by Neurospora crassa 2-nitropropane dioxygenase was investi

63 Catalytic turnover of Neurospora crassa 2-nitropropane dioxygenase with nitroe

64 with the corresponding dicer-like genes from Neurospora crassa [Ncdcl-1 (50.5%); Ncdcl-2 (38.0%)] and

65 NcLPMO9C from Neurospora crassa acts both on cellulose and on non-cell

66 of the homolog in the filamentous ascomycete Neurospora crassa affects the circadian clock output, yi

67 aken centre-stage over the last few decades--Neurospora crassa and Aspergillus nidulans.

68 rgillus nidulans, Aspergillus fumigatus, and Neurospora crassa and expressed the genes as secreted pr

69 yed stage-specific expression and editing in Neurospora crassa and F. verticillioides Furthermore,F.

70 f4, inhibits growth of the ascomycete fungi, Neurospora crassa and Fusarium graminearum, at micromola

71 analyzed H3K27me3 in the filamentous fungus Neurospora crassa and in other Neurospora species.

72 he ascomycete fungi Fusarium graminearum and Neurospora crassa and induces accumulation of reactive o

73 The DEAD-box proteins CYT-19 in Neurospora crassa and Mss116p in Saccharomyces cerevisia

74 The DEAD-box proteins CYT-19 in Neurospora crassa and Mss116p in Saccharomyces cerevisia

75 In Neurospora crassa and other filamentous fungi, light-dep

76 wealth of sequence information available for Neurospora crassa and other fungi has greatly facilitate

77 In Neurospora crassa and Saccharomyces cerevisiae, efficien

78 In Neurospora crassa and Saccharomyces cerevisiae, the latt

79 Recent work in Neurospora crassa and Sclerotinia sclerotiorum has illum

80 ferase center (PTC) function was analyzed in Neurospora crassa and wheat germ translation extracts us

81 6p of Saccharomyces cerevisiae and CYT-19 of Neurospora crassa are ATP-dependent helicases that funct

82 ic MLEs and that of CMLE from the eukaryotic Neurospora crassa are completely different from that of

83 The Neurospora crassa arg-2 uORF encodes the 24-residue argi

84 ces cerevisiae GCN4, S. cerevisiae CPA1, and Neurospora crassa arg-2, regulation by uORFs controls ex

85 eatures using an in vivo tethering system in Neurospora crassa Artificial recruitment of the H3K9 met

86 Here, we use Neurospora crassa as a model filamentous fungus to inter

87 Using the cellulolytic fungus Neurospora crassa as a model, we identified a xylodextri

88 structure of LAD from the filamentous fungus Neurospora crassa at 2.6 A resolution.

89 nted these issues in the microbial eukaryote Neurospora crassa by using a "reverse-ecology" populatio

90 r the structure of the ring of c subunits in Neurospora crassa by using data from the crystal structu

91 the reconstitution of NSP ubiquitylation in Neurospora crassa cell extracts.

92 Here we identified Neurospora crassa centromeric DNA by chromatin immunopre

93 present a comprehensive dynamic model of the Neurospora crassa circadian clock that incorporates its

94 In the Neurospora crassa circadian clock, a protein complex of

95 The Neurospora crassa circadian negative element FREQUENCY (

96 Neurospora crassa colonizes burnt grasslands and metabol

97 Neurospora crassa colonizes burnt grasslands in the wild

98 O system conserved between S. cerevisiae and Neurospora crassa compared with that which has evolved i

99 The Neurospora crassa CYT-18 protein is a mitochondrial tyro

100 s studies showed that one of these proteins, Neurospora crassa CYT-18, binds group I introns by using

101 The Neurospora crassa DEAD-box protein CYT-19 is a mitochond

102 ATPase, we have generated mutant strains of Neurospora crassa defective in six subunits, C, H, a, c,

103 Notably, the only other NMO from Neurospora crassa for which biochemical evidence is avai

104 The hydrophobin EAS from the fungus Neurospora crassa forms functional amyloid fibrils calle

105 study explores the relative contributions of Neurospora crassa G alpha subunits, gna-1, gna-2, and gn

106 -cell communication and fusion in the fungus Neurospora crassa Genetically identical germinating spor

107 Prior to initiation of this project, the Neurospora crassa genome assembly contained only 3 of th

108 Neurospora crassa has been a model organism for the stud

109 Neurospora crassa has been for decades a principal model

110 The filamentous fungus Neurospora crassa has been shown to be missing homologs

111 Neurospora crassa has been utilized as a model organism

112 The eukaryotic filamentous fungus Neurospora crassa has proven to be a dependable model sy

113 ental mechanisms in Aspergillus nidulans and Neurospora crassa have been intensively studied, leading

114 e control and function of DNA methylation in Neurospora crassa have led to a greater understanding of

115 Genetics studies of Neurospora crassa have revealed that a DNA methyltransfe

116 ccharomyces pombe and the filamentous fungus Neurospora crassa have served as important model systems

117 and disiRNA locus DNA methylation (DLDM) in Neurospora crassa Here we show that the conserved exonuc

118 n X-ray crystal structures of an enzyme from Neurospora crassa in the resting state and of a copper(I

119 Neurospora crassa is a heterothallic filamentous fungus

120 The filamentous fungus Neurospora crassa is a model laboratory organism, but in

121 The eukaryotic model organism Neurospora crassa is an excellent system to study evolut

122 This hyphal type in Neurospora crassa is being used as a model for studies o

123 The model filamentous fungus Neurospora crassa is capable of utilizing a variety of c

124 at heterochromatin in the filamentous fungus Neurospora crassa is marked by cytosine methylation dire

125 The fluffy (fl) gene of Neurospora crassa is required for asexual sporulation an

126 n transcription/translation feedback loop in Neurospora crassa is the protein FREQUENCY (FRQ), shown

127 The bifunctional Neurospora crassa mitochondrial tyrosyl-tRNA synthetase

128 One such protein, the Neurospora crassa mitochondrial tyrosyl-tRNA synthetase

129 rystal structure of a C-terminally truncated Neurospora crassa mitochondrial tyrosyl-tRNA synthetase

130 The Neurospora crassa mitochondrial tyrosyl-tRNA synthetase

131 studies on the Schizosaccharomyces pombe and Neurospora crassa Nbp2p orthologues and the high conserv

132 ning sensors, such as BarA and TorS; and the Neurospora crassa Nik-1 (Os-1) sensor that contains a ta

133 In this study, we show that the Neurospora crassa osmosensing MAPK pathway, essential fo

134 The Neurospora crassa photoreceptor Vivid tunes blue-light r

135 The filamentous fungus Neurospora crassa played a central role in the developme

136 We show that the model cellulolytic fungus Neurospora crassa relies on a high-affinity cellodextrin

137 Using Neurospora crassa repeat-induced point mutation (RIP) as

138 analysis of how the model filamentous fungus Neurospora crassa responds to the three main cell wall p

139 estigating the introns of the model organism Neurospora crassa revealed a different organization at t

140 Neurospora crassa sports features of heterochromatin fou

141 cell extracts derived from MacroD-deficient Neurospora crassa strain exhibit a major reduction in th

142 e polymorphisms (SNPs) between the reference Neurospora crassa strain Oak Ridge and the Mauriceville

143 implement our algorithm on a real dataset of Neurospora crassa strains, using the genetic and geograp

144 th an MTS derived from S. cerevisiae OXA1 or Neurospora crassa SU9, both coding for hydrophobic mitoc

145 n Mss116 and the related protein Cyt-19 from Neurospora crassa suggest that these proteins form a sub

146 Studies with the Neurospora crassa synthetase (CYT-18 protein) showed tha

147 ral potential new PMO families in the fungus Neurospora crassa that are likely to be active on novel

148 me-mediated TER 3'-end cleavage mechanism in Neurospora crassa that is distinct from that found speci

149 critical component of the circadian clock of Neurospora crassa that regulates the abundance of its co

150 (Hi-C) with wild-type and mutant strains of Neurospora crassa to gain insight into the role of heter

151 therefore used the model filamentous fungus Neurospora crassa to search for uncharacterized transcri

152 uction of the NPS6 ortholog from the saprobe Neurospora crassa to the Deltanps6 strain of C. heterost

153 We initially identified TER from Neurospora crassa using a novel deep-sequencing-based ap

154 We have successfully applied BiFC in Neurospora crassa using two genes involved in meiotic si

155 Neurospora crassa utilizes DNA methylation to inhibit tr

156 y, the ncd-2 gene encoding for the enzyme in Neurospora crassa was cloned, expressed in Escherichia c

157 The complex from Neurospora crassa was composed of Tob55-Sam50, Tob38-Sam

158 A heterologous expression method in Neurospora crassa was developed as a step toward connect

159 In this research, the urease-positive fungus Neurospora crassa was investigated for the biomineraliza

160 of the clock in the circadian model organism Neurospora crassa We show that, in a ras2-deficient stra

161 Different PMOs isolated from Neurospora crassa were found to generate oxidized cellod

162 lopsis (formerly Mortierella) ramanniana and Neurospora crassa were introduced into maize using an em

163 eacetylase 1 (HDA1) mutant (hda-1) strain of Neurospora crassa with inactivated histone deacetylase 1

164 laser scanning microscopy that a LPMO (from Neurospora crassa) introduces carboxyl groups primarily

165 was initially inoculated with the mycelium (Neurospora crassa), and following the initial incubation

166 In Neurospora crassa, a circadian rhythm of conidiation (as

167 In contrast, the histone modifications in Neurospora crassa, a convenient model organism for multi

168 In Neurospora crassa, a eukaryotic model system for studyin

169 cell communication in the filamentous fungus Neurospora crassa, a simple and experimentally amenable

170 In Neurospora crassa, a single H3K9 methyltransferase compl

171 In Neurospora crassa, a transcription factor, WCC, activate

172 e TPP riboswitches in the filamentous fungus Neurospora crassa, and found that one activates and two

173 derstand the role of MAP kinase signaling in Neurospora crassa, and to identify downstream target gen

174 In the lowly bread mould, Neurospora crassa, biomolecular reactions involving the

175 lamentous fungi, such as the model eukaryote Neurospora crassa, but is absent from the genomes of bak

176 re essential for light-mediated responses in Neurospora crassa, but the molecular mechanisms underlyi

177 In the filamentous fungus Neurospora crassa, cell fusion occurs during asexual spo

178 of a Moco-free eukaryotic NR from the fungus Neurospora crassa, documenting that Moco is necessary an

179 Zymoseptoria tritici, Magnaporthe oryzae and Neurospora crassa, exhibited PAMP activity, inducing cel

180 tein purified from one of its natural hosts, Neurospora crassa, exists in a multimeric form and has t

181 In the filamentous fungus Neurospora crassa, genetically identical asexual spores

182 In the fungus Neurospora crassa, H3K9me3 and 5mC are catalyzed, respec

183 an RdRP component of the quelling pathway in Neurospora crassa, have rapidly diverged in evolution at

184 In the filamentous fungus Neurospora crassa, HET-C regulates a conserved programme

185 ng a genetic screen of the ascomycete fungus Neurospora crassa, in which dynein is nonessential.

186 A model filamentous fungus, Neurospora crassa, is a multinucleate system used to elu

187 We demonstrate that an LPMO from Neurospora crassa, NcLPMO9C, indeed degrades various hem

188 Using the model filamentous fungus, Neurospora crassa, our microfluidic system enabled direc

189 In Neurospora crassa, pairing of homologous DNA segments is

190 FEX KOs in three eukaryotic model organisms, Neurospora crassa, Saccharomyces cerevisiae, and Candida

191 central component of the circadian clock in Neurospora crassa, shows daily cycles that are exquisite

192 In Neurospora crassa, the circadian clock generates daily r

193 In Neurospora crassa, the frq, wc-1, and wc-2 genes encode

194 lletotrichum graminicola, the model organism Neurospora crassa, the human pathogen Sporothrix schenck

195 In the filamentous fungus Neurospora crassa, the IME2 homolog (ime-2) is not requi

196 In Neurospora crassa, the interactions between products of

197 Among natural accessions of Neurospora crassa, there is significant variation in clo

198 In Neurospora crassa, three allelic specificities at the he

199 acultative and constitutive heterochromatin, Neurospora crassa, to explore possible interactions betw

200 During meiosis in the filamentous fungus Neurospora crassa, unpaired genes are identified and sil

201 In Neurospora crassa, unpaired genes are silenced by a mech

202 This system, derived from genes in Neurospora crassa, uses the transcriptional activator QF

203 In Neurospora crassa, VIVID (VVD), a small LOV domain conta

204 tween H3S10p, H3K9me, and DNA methylation in Neurospora crassa, we built and tested mutants of the pu

205 lear movement in the model ascomycete fungus Neurospora crassa, we show that genetic diversity is mai

206 y are acutely active in the meiotic cells of Neurospora crassa, where they evaluate the mutual identi

207 In this study, we employed LPMO9C from Neurospora crassa, which is active toward cellulose and

208 g regulation by a fungal TPP riboswitch from Neurospora crassa, which is mostly located in a large in

209 in single cells of the model fungal system, Neurospora crassa, with droplet microfluidics and the us

210 i in general other than the model ascomycete Neurospora crassa--has been neglected, leaving this type

211 haromyces pombe, and one filamentous fungus, Neurospora crassa-three species that arguably are not re

212 on selection in the model filamentous fungus Neurospora crassa.

213 rmal hyphal growth in the filamentous fungus Neurospora crassa.

214 PAF26 has been characterized in detail using Neurospora crassa.

215 xual sporulation in the multicellular fungus Neurospora crassa.

216 sexual sporulation in the filamentous fungus Neurospora crassa.

217 st to control repetitive selfish elements in Neurospora crassa.

218 lue light responses in the filamentous fungi Neurospora crassa.

219 lass of small RNAs in the filamentous fungus Neurospora crassa.

220 protein complexes in the filamentous fungus Neurospora crassa.

221 in the adaptation of blue-light responses in Neurospora crassa.

222 egulator protein from the filamentous fungus Neurospora crassa.

223 f the RNAi pathway in the filamentous fungus Neurospora crassa.

224 idial germination in the filamentous fungus, Neurospora crassa.

225 ed as a component of the circadian system in Neurospora crassa.

226 and maintenance of regular hyphal growth in Neurospora crassa.

227 uring colony initiation in the fungal model, Neurospora crassa.

228 In Neurospora, deletion of ric8 leads to profound defects i

229 Similar to reports in Drosophila, Neurospora Deltaric8 strains have greatly reduced levels

230 me3 in N. crassa are also H3K27me3-marked in Neurospora discreta and Neurospora tetrasperma.

231 immunoprecipitation (Co-IP) experiments, the Neurospora DNA methyltransferase DIM-2 was found in a co

232 We identified a JmjC domain protein in Neurospora, DNA METHYLATION MODULATOR-1 (DMM-1), that pr

233 n oscillators in model systems as diverse as Neurospora, Drosophila, and mammalian cells is thought t

234 Our findings show that Neurospora extracts can be used as a tool to dissect mec

235 ic expression and the proper function of the Neurospora FREQUENCY (FRQ) protein are essential for cir

236 h et al. demonstrate that phosphorylation of Neurospora FRQ induces a conformational change, which ca

237 Here we show that, unlike most genes in Neurospora, frq exhibits non-optimal codon usage across

238 In the filamentous fungus Neurospora, FRQ, FRH, WC-1, and WC-2 are the core compon

239 defective-2 interacting protein (qip(+)), a Neurospora gene whose function is essential to silencing

240 during the meiotic homolog pairing stage in Neurospora generates a sequence-specific signal that sil

241 ave created strains bearing deletions of 103 Neurospora genes encoding transcription factors.

242 B and at 11 lysines in hda-1 H2B, suggesting Neurospora H2B is a complex combination of different ace

243 Neurospora has two active and clearly distinct RNA inter

244 ne/threonine protein kinase-29 (STK-29), the Neurospora homolog of mammalian WEE1 kinase.

245 The disruption of qip in Neurospora impaired gene silencing and siRNA accumulated

246 early genes (such as frq, al-3, and vvd) in Neurospora, in which light induces the binding of identi

247 ized and sequenced from a subset of the same Neurospora individuals.

248 The predicted branch point sequences of Neurospora introns are much closer to the 3' splice site

249 In addition, Neurospora introns lack the canonical polypyrimidine tra

250 DNA methylation in Neurospora is dependent on trimethylation of histone H3

251 We conclude that DNA methylation in Neurospora is largely or exclusively the result of a uni

252 Quelling in Neurospora is one of the first known RNAi-related phenom

253 In Neurospora, it was proposed that the FREQUENCY (FRQ) pro

254 By systematically screening the Neurospora knock-out library, we identified RTT109 as a

255 vely, strongly suggesting that the rhythm in Neurospora lacking frq function simply is driven by the

256 In Neurospora, meiotic drive can be observed in fungal spor

257 In Neurospora, metabolic oscillators coexist with the circa

258 The maturation of the Neurospora microRNA-like sRNA, milR-1, requires the Argo

259 e make use of yeast recombinational cloning, Neurospora mutant strains deficient in nonhomologous end

260 In the model system Neurospora, normal circadian rhythmicity requires a TTFL

261 on in the ras-1(bd) mutant suggests that the Neurospora photoreceptor WHITE COLLAR-1 is a target of R

262 The WCC is also the principal Neurospora photoreceptor; WCC-mediated light induction o

263 We found that three components of the Neurospora Polycomb repressive complex 2 (PRC2)--[Su-(va

264 for H3K27me3, whereas the fourth component, Neurospora protein 55 (an N. crassa homolog of p55/RbAp4

265 ystem based on the regulatory genes from the Neurospora qa gene cluster.

266 The circadian system in Neurospora remains a premier model system for understand

267 q) identified circadianly expressed genes in Neurospora, revealing that from approximately 10% to as

268 bacteriorhodopsin, sensory rhodopsin II, and Neurospora rhodopsin.

269 Furthermore, the Neurospora RNA interference mutants show increased sensi

270 Neurospora's light responses are transient, that is, fol

271 tides long (several nucleotides shorter than Neurospora siRNAs), with a strong preference for uridine

272 one of their mat chromosomes, with multiple Neurospora species acting as donors.

273 entous fungus Neurospora crassa and in other Neurospora species.

274 d WHITE COLLAR-2 proteins is integral to the Neurospora system.

275 The Neurospora tetrasperma mating-type chromosomes have been

276 omic data sets of the filamentous ascomycete Neurospora tetrasperma, a fungus that lacks recombinatio

277 In the fungus Neurospora tetrasperma, it has been proposed that this m

278 determining locus of the self-fertile fungus Neurospora tetrasperma.

279 on through high-speed imaging of ejection in Neurospora tetrasperma.

280 o H3K27me3-marked in Neurospora discreta and Neurospora tetrasperma.

281 Here, we show that in the filamentous fungus Neurospora, the Argonaute homolog QDE-2 and its slicer f

282 In Neurospora, the circadian rhythm is expressed as rhythmi

283 In Neurospora, the FREQUENCY protein closes the circadian n

284 During the early stages of meiosis in Neurospora, the symmetry of homologous chromosomal regio

285 In animal systems as well as Neurospora, transcriptional repression is believed to oc

286 We show that Neurospora U2AF65 binds RNA with low affinity and specif

287 nine/serine rich domain at the N-terminus of Neurospora U2AF65 regulates its RNA binding.

288 ant step in the substrate recognition of the Neurospora Varkud Satellite (VS) ribozyme is the formati

289 The Neurospora Varkud Satellite (VS) ribozyme provides a mod

290 In the Neurospora VS ribozyme, magnesium ions facilitate format

291 most essential light signaling components in Neurospora, VVD and WCC, illuminating a previously uncha

292 The clock gene period-4 (prd-4) in Neurospora was identified by a single allele displaying

293 ccharomyces and the model filamentous fungus Neurospora, we examine intrinsic restraints on recombina

294 In Neurospora, we found that elimination of any member of t

295 To facilitate forward genetics in Neurospora, we have adapted microarray-based restriction

296 is study, by using purified FRQ protein from Neurospora, we identified 43 in vivo FRQ phosphorylation

297 y of this TTFL to the circadian mechanism in Neurospora, we used low-amplitude temperature cycles to

298 ock-controlled genes (ccgs) was pioneered in Neurospora where circadian output begins with binding of

299 circadian rhythms of Drosophila, humans, and Neurospora, where CK1 and CK2 are emerging as the main p

300 hylation and acetylation of core histones in Neurospora, which should serve as a foundation for futur