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1 ORR (67% vs 49%, P = .08) and complete response (CR) or
2 ORR and median PFS were similar in patients with T790M-p
3 ORR in the intention-to-treat (ITT) population was 17% (
4 ORR in the liver was improved with the addition of SIRT
5 ORR of 97% and >/=VGPR 73% were seen in patients not ref
6 ORR was 28% (nine of 32) in patients with any degree of
7 ORR was 37.5% with a complete response rate of 12.5%, me
8 ORR was 41% (7/17); 6 additional patients (35%) had stab
9 ORR was 46% (95% CI, 34 to 57) for cabozantinib versus 1
10 ORR was 6% (five of 83) for glembatumumab vedotin versus
11 ORR was 60% and was generally consistent across subgroup
12 ORR was 66% (EBd) vs 63% (Bd).
13 ORR was evaluated on the basis of PD-L1 IC expression (I
14 ORR was higher with mutations in DNMT3A and lower for SR
15 ORRs were similar in patients who did and patients who d
16 patients with follicular lymphoma (n = 149), ORR seemed higher for obinutuzumab than rituximab (44.6%
18 ein we report the discovery of a dominant 4e-ORR over the whole potential range on {310} surface of A
19 Four-electron oxygen reduction reaction (4e-ORR), a key pathway in energy conversion, is preferred o
20 ere exceptionally capable to catalyze the 4e-ORR in alkaline solution, though limited within a narrow
24 hat high ORR (eg, statistically exceeding an ORR of 30%) is an appropriate end point for single-arm t
25 therapy following KI discontinuation with an ORR to subsequent KI at 50% and a median PFS of 11.9 mon
26 PFS varied by histology ( P < .001), and ORR was higher in patients with significant papillary (s
27 he ORR ratio (1.09; 90% CI, 0.974-1.211) and ORR difference (5.53; 95% CI, -3.08 to 14.04) were withi
28 rial-level PFS hazard ratio (HR), OS HR, and ORR odds ratio were analyzed using a weighted linear reg
31 activity of our carbon foam for both OER and ORR independently, in a three-electrode configuration, a
35 ectively) had markedly superior PFS, OS, and ORR compared with patients with right-sided tumors (n =
36 ectively) had markedly superior PFS, OS, and ORR compared with patients with right-sided tumors (n =
37 ed a significant clinical benefit in PFS and ORR over standard-of-care sunitinib as first-line therap
40 alytic performance than the state of the art ORR catalyst (Pt/C) and the oxygen evolution reaction ca
42 achieved in relation with the graphene based ORR catalysts applicable for MFCs, still their collectiv
44 ental strategies of competent graphene based ORR catalysts, which are not only applicable for MFCs bu
48 erial, denoted CPM-99Fe/C, exhibits the best ORR activity, comparable to benchmark 20% Pt/C in alkali
53 electrocatalysts with high activity for both ORR and OER reactions and their streamlined coupling pro
56 provide a promising avenue to develop cheap ORR catalysts from inexpensive, scalable and biological
58 guration with the nonprecious pCNT@Fe@GL/CNF ORR electrode and Ni-Fe LDH/NiF oxygen evolution reactio
63 consistent with the well-known pH-dependent ORR selectivity catalyzed by graphitic carbon materials.
64 90%-96%) and ibrutinib in relapsed disease (ORR 30%-55%), the Alliance for Clinical Trials in Oncolo
69 n of the Shoup-Szabo equation for extracting ORR mass transport parameters using thin ionomer films w
70 vity comparable to IrO2 for OER and Pt/C for ORR, respectively, along with remarkable long term stabi
72 viously shown to be excellent candidates for ORR in terms of both activity and long-term stability, f
74 11.5 milliamperes per square centimeter for ORR (at 0.9 volts versus reversible hydrogen electrode),
76 undaries were 0.81 to 1.24 with a 90% CI for ORR ratio (proposed biosimilar/trastuzumab) and -15% to
77 d RuO2 as a bifunctional electrocatalyst for ORR and OER, and hold a promise as efficient air electro
80 arbon-based, metal-free electrocatalysts for ORR and various defects in metal oxides/selenides for OE
85 ter activity and much enhanced stability for ORR and ethanol-oxidation reaction (EOR) than those of d
87 oped carbon material is promising metal-free ORR catalyst for fuel cells and capacitor electrode mate
90 ast, nanoframes which exhibit extremely high ORR activity simultaneously demonstrate more significant
91 Pt (110) facets of the nanoplates have high ORR specific and mass activities that reach 7.8 milliamp
95 ients with high BCL2 expression had a higher ORR (94% [17/18]) than patients with low BCL2 expression
97 treated patients showed significantly higher ORR (72% v 55%; P = .0038), longer time to first dose re
98 ivity, where a approximately 25 times higher ORR activity than for commercial Pt/C (2.7 A mgPt(-1) at
101 (DFT) calculations reveal that the improved ORR activity on the PdCuM NPs stems from the catalytical
105 alysts, respectively, and are also stable in ORR conditions, making them among the most efficient ele
106 onto the Mn-graphene nanocomposite increased ORR performance significantly, with a peak potential shi
107 t OV exhibited the highest diffusion-limited ORR current (5.5 mA cm(-2) ) among a series of lambda-Mn
111 1 cancer type, the mean ORR and the maximum ORR statistically exceeded were calculated, and their as
113 nation of agents for 1 cancer type, the mean ORR and the maximum ORR statistically exceeded were calc
114 rmation process through correlating measured ORR activity with the change of chemical bonds in precur
116 results from supported and soluble molecular ORR electrocatalysts must be interpreted with caution, a
123 ol experiments show that such enhancement of ORR by the AuNC is specific to nanoclusters and not to p
125 vity, strategies behind the modifications of ORR catalysts and update the research efforts devoted on
126 review is to outline the significant role of ORR catalysts, factors influencing the ORR activity, str
131 positive for T790M who had better outcomes (ORR, 69%; PFS, 16.5 months) as well as a subset of patie
132 ative plasma had overall favorable outcomes (ORR, 46%; median PFS, 8.2 months), tumor genotyping dist
136 ilar in patients with T790M-positive plasma (ORR, 63%; PFS, 9.7 months) or T790M-positive tumor (ORR,
137 ved 90% enhancement or 40% suppression in Pt ORR activity under compression or tension, respectively,
138 R) in four patients [(overall response rate (ORR) = 9%, 95% confidence interval [CI] 3% to 22%)].
139 tion of response, and overall response rate (ORR) according to the presence of del(17p) compared with
140 objectives included objective response rate (ORR) and 24-week progression-free survival (PFS) rate; o
149 itor, demonstrated an overall response rate (ORR) of 60% in advSM but biomarkers predictive of respon
151 uate the safety and objective response rate (ORR) of imiquimod in combination with systemic albumin b
153 r BV plus DTIC, the objective response rate (ORR) was 100% and the complete remission (CR) rate was 6
155 uable population, the overall response rate (ORR) was 56% (29/52) and was similar between the 10 mg/k
158 or number of doses, objective response rate (ORR) was significantly higher in patients who experience
159 erall survival, and objective response rate (ORR) were 11.0 months, 18.5 months, and 29%, respectivel
160 survival (OS), and objective response rate (ORR) were assessed according to tumor location and treat
161 survival (OS), and objective response rate (ORR) were assessed according to tumor location and treat
162 s were calculated for overall response rate (ORR) within 6 months, 9-month progression-free survival
163 y end points included overall response rate (ORR), duration of response (DOR), progression-free survi
165 t was composite CNS objective response rate (ORR), requiring all of the following: >/= 50% reduction
166 verall survival (OS), overall response rate (ORR), response duration (RD), time to treatment failure
175 follicular lymphoma (overall response rate [ORR] 90%-96%) and ibrutinib in relapsed disease (ORR 30%
179 eduction reaction/oxygen evolution reaction (ORR/OER) catalytic activities of p-orbital heteroatom-do
180 specific and mass oxygen reduction reaction (ORR) activities with improvement factors of 51.1 and 34.
181 ecessary to boost oxygen reduction reaction (ORR) activity in core/shell M/platinum (Pt) catalysts (w
182 and a comparable oxygen reduction reaction (ORR) activity to that of Pt/C as well as a better stabil
183 of Pt during the oxygen reduction reaction (ORR) affects the performance and economic viability of f
184 ytic site for the oxygen reduction reaction (ORR) and (ii) demonstration of competitive PEFC performa
185 stability for the oxygen-reduction reaction (ORR) and liquid fuel oxidation reaction is very importan
186 catalysts for the oxygen reduction reaction (ORR) and other electrocatalytic processes requires detai
188 catalysts for the oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) in fuel cells o
189 catalysts for the oxygen-reduction reaction (ORR) and oxygen-evolution reaction (OER) is critical for
190 is, including the oxygen-reduction reaction (ORR) and oxygen-evolution reaction (OER), is a critical
191 taneously for the oxygen reduction reaction (ORR) and the oxygen evolution reaction (OER) is currentl
192 ns (OH(-)) by the oxygen reduction reaction (ORR) at a diffusion-controlled rate in aerated phosphate
193 l modification of oxygen reduction reaction (ORR) catalysts to improve the maximum volumetric power d
195 irst study of the oxygen reduction reaction (ORR) catalyzed by a cofacial porphyrin scaffold accessed
196 c activity toward oxygen reduction reaction (ORR) compared to Pt/C catalyst in both alkaline and acid
197 ctrocatalysis for oxygen reduction reaction (ORR) for proton exchange membrane fuel cells (PEMFCs) ar
198 w kinetics of the oxygen reduction reaction (ORR) impede the widespread uptake of low-temperature fue
199 materials for the oxygen reduction reaction (ORR) in acidic media, which is crucial for large-scale d
200 a reactant in the oxygen reduction reaction (ORR) in alkaline media, an adequate supply of water is r
203 ctro-catalyst for oxygen reduction reaction (ORR) in proton exchange membrane (PEM) fuel cells, oxyge
204 tive site for the oxygen reduction reaction (ORR) is different under acidic and alkaline conditions.
205 efficiency of the oxygen reduction reaction (ORR) is furnished from a systematic electrochemical stud
207 athode towards an oxygen reduction reaction (ORR) is one of the high-priority research directions for
208 work reports the oxygen reduction reaction (ORR) kinetics of metal nanoparticle catalysts between 50
209 of the multi-step oxygen reduction reaction (ORR) makes it difficult to investigate the oxygen dissoc
210 We find that the oxygen-reduction reaction (ORR) on CNTs initially produces LiO2, which subsequently
212 esulting from the oxygen reduction reaction (ORR) or hydrogen peroxide reduction on platinum, has bee
213 activity for the oxygen reduction reaction (ORR) requires optimization of both the specific activity
215 that facilitates the O2 reduction reaction (ORR), a PCET process important in fuel cells and O2 redu
216 c activity in the oxygen reduction reaction (ORR), as evidenced by an onset potential of +0.97 V, exc
217 rsion through the oxygen reduction reaction (ORR), carbon-based metal-free catalysts have also been d
218 EMFC), namely the oxygen reduction reaction (ORR), necessitates an accurate and detailed structural u
219 ctivities for the oxygen reduction reaction (ORR), oxygen evolution reaction (OER), and hydrogen evol
220 actions including oxygen reduction reaction (ORR), oxygen evolution reaction (OER), and hydrogen evol
226 the two-electron oxygen reduction reaction (ORR); however, the chemical potential of H2 replaces an
227 molecular oxygen (oxygen reduction reaction, ORR), which makes them fuel-cell cathode catalysts with
228 he oxygen reduction and evolution reactions (ORR and OER) are vital for the performances of rechargea
231 w the contributions of the oxygen reduction (ORR) and the oxygen evolution (OER) half-reactions on th
232 tic search was used to identify the reported ORR for each eligible treatment arm that had been presen
233 atomic Fe catalyst has achieved respectable ORR activity in challenging acidic media (0.5 M H2SO4),
235 R activity) and Pt/C (92 % vs. 78 % retained ORR activity after 10 h running) in alkaline electrolyte
236 of the polydopamine-coated material revealed ORR occurring via 4.14 and 4.00 electrons, respectively.
240 h azacitidine-based combinations had similar ORR to azacitidine monotherapy, although patients with C
241 ombination of PomCyDex results in a superior ORR and PFS compared with PomDex in patients with lenali
242 ted with polydopamine, resulting in superior ORR activity compared to the uncoated PDA structures.
243 potential trial end points demonstrated that ORR statistically exceeding 30% with a single agent had
262 carfilzomib plus low-dose dexamethasone, the ORR was 55% with a safety profile comparable to that of
263 polarized sufficiently negative to drive the ORR or H2O2 reduction on the platinum surface, mainly us
264 The nanoporous Pt surface formed during the ORR was visualized by AFM and high-resolution SEM, which
266 is then applied to successfully explain the ORR/OER activities of other transition-metal spinels, in
268 electrocatalysts have been designed for the ORR or the OER; however, the origin of the advanced acti
271 dral site is the activity descriptor for the ORR/OER of spinels, consolidating the role of electron o
273 of transferred electrons (n) involved in the ORR was >3.8, indicating a dominant quasi-4-electron pat
274 the addition of dexamethasone increased the ORR with all responses of >/=partial response occurring
275 le of ORR catalysts, factors influencing the ORR activity, strategies behind the modifications of ORR
276 up of 23 months (range, 1 to 43 months), the ORR was 38% for patients receiving azacitidine, 49% for
280 By comparing theoretical calculations of the ORR selectivity at a well-defined graphene nanostructure
282 e prior therapies (range, two to seven), the ORR was 19%; median response duration, 6.0 months (95% C
283 en applied to acidic electrolytes, shows the ORR preferring the two-electron pathway, consistent with
290 superior electrocatalytic activities towards ORR, besides excellent stability and good methanol toler
291 utstanding electrocatalytic activity towards ORR comparable to the commercial Pt/C catalyst in neutra
293 RR and 79 (6.1%) of 1292 patients undergoing ORR (RR, 1.17; 95% CI, 0.89-1.53; P = .26; I2 = 0%) in 9
294 R and 104 (10.4%) of 998 patients undergoing ORR (RR, 1.31; 95% CI, 1.05-1.64; P = .02; I2 = 0%) in 5
298 it, including uRCC, where it correlated with ORR (43% v 11%), median PFS (12.9 v 1.9 months), and ove
299 95, to June 30, 2016, that compared LRR with ORR for histologically proven rectal cancer in adult pat
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