ライフサイエンスコーパス: P. haemolytica

1 P. haemolytica incubated with H-DDDDDD-OH in zinc saline

2 romosome by Cre recombinase expressed from a P. haemolytica plasmid.

3 The presence of antibodies against P. haemolytica outer membrane proteins (OMPs) correlates

4 inst PlpE contribute to host defense against P. haemolytica.

5 omA was surface exposed, was conserved among P. haemolytica biotype A serotypes, and had porin activi

6 protective antigen for GBM, E. coli K1, and P. haemolytica A2, protein conjugates of it are easy to

7 nchymal damage caused by factors released by P. haemolytica, neutrophils contribute to the pathologic

8 eutrophil infiltration into the lungs during P. haemolytica pneumonia are poorly characterized.

9 tatistically with resistance to experimental P. haemolytica challenge in cattle.

10 Our findings support a role for P. haemolytica LPS and TNF-alpha in the induction of IL-

11 hat there may be a specific binding site for P. haemolytica leukotoxin on bovine but not on porcine o

12 and PomB, respectively), were extracted from P. haemolytica by solubilization in N-octyl polyoxyl eth

13 a role for the lipopolysaccharide (LPS) from P. haemolytica in the induction of proinflammatory cytok

14 o quantitate leukotoxin promoter activity in P. haemolytica and to demonstrate that transcription was

15 hloramphenicol resistance gene (cat, CmR) in P. haemolytica (pNF2200).

16 , indicating that PlpE is surface exposed in P. haemolytica and assumes a similar surface-exposed con

17 ined the kinetics of IL-8 mRNA expression in P. haemolytica LPS-stimulated bovine alveolar macrophage

18 Expression of PIC was induced at 2 h p.i. in P. haemolytica-infected cattle and continued to 4 h p.i.

19 ma and TNF-alpha genes were not increased in P. haemolytica-inoculated CD18(-) cattle lungs compared

20 ould be useful for future genetic studies in P. haemolytica and could potentially be applied to other

21 a consequence of the unusual codon usage in P. haemolytica genes.

22 We found that intact P. haemolytica and recombinant E. coli expressing PlpE a

23 terless cat cassette and then delivered into P. haemolytica on a shuttle vector.

24 Cattle vaccinated with live P. haemolytica developed a significant increase in serum

25 that encodes a transcriptional activator of P. haemolytica leukotoxin expression.

26 ssion of some PIC genes, as a consequence of P. haemolytica infection.

27 8(+) and CD18(-) cattle after inoculation of P. haemolytica.

28 l2 (zinc saline solution) induced killing of P. haemolytica and other bacteria comparable to defensin

29 served a significant reduction in killing of P. haemolytica when bovine immune serum that was deplete

30 and streptomycin (SmR) resistant plasmid of P. haemolytica called pYFC1.

31 dies recognize a protein in all serotypes of P. haemolytica except serotype 11.

32 culture supernatant from a mutant strain of P. haemolytica that does not produce any detectable leuk

33 th culture filtrates from a mutant strain of P. haemolytica that does not produce biologically active

34 Of the six P. haemolytica ribotypes, two ribotypes predominated.

35 Until now, specific P. haemolytica OMPs which elicit antibodies that functio

36 Recent studies indicate that P. haemolytica Lkt binds to bovine CD18, the common subu

37 The P. haemolytica hsdMSR genes were mapped using transposon

38 The P. haemolytica strain used was a mutant serotype A1 from

39 Plasmid pNF2176 carries the P. haemolytica ROB-1 beta-lactamase gene (blaP, ApR) and

40 ix different ribotypes were observed for the P. haemolytica isolates, while only one ribotype was obs

41 Expression of the P. haemolytica R-M genes in E. coli was inefficient and

42 ons of all known Hsd aa sequences placed the P. haemolytica and H. influenzae proteins into a new gro

43 In this study, the P. haemolytica lktC mutant was shown to be less virulent

44 Therefore, P. haemolytica LKT binds rapidly to susceptible and to r

45 beginning, while their antibody responses to P. haemolytica antigens were delayed.

46 ay represent an important mechanism by which P. haemolytica overwhelms host defenses, contributing to

47 hree different bovine immune sera with whole P. haemolytica cells resulted in a reduction of bovine i

48 The induction of gene expression with P. haemolytica inoculation was more prominent in CD18(-)

49 Cattle were infected with P. haemolytica via fiberoptic deposition of organisms in

50 onchi and bronchioles of lungs infected with P. haemolytica, three Holstein calves homozygous for bov

51 normal CD18 expression) were inoculated with P. haemolytica A1 via a fiberoptic bronchoscope and euth

52 the lungs of CD18(+) cattle inoculated with P. haemolytica was greater than that in lungs of the CD1

53 Incubation of bovine leukocytes with P. haemolytica leukotoxin caused marked cytoplasmic memb