ライフサイエンスコーパス: P450 inhibitor

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1 sed inactivator for the design of cytochrome P450 inhibitors.

2 The cytochrome P450 inhibitor 1-aminobenzotriazole blocked the VPA-stim

3 s completely abolished by treatment with the P450 inhibitor 1-aminobenzotriazole.

4 d was coadministered with the pan-cytochrome P450 inhibitor 1-aminobenzotriazole.

5 carbonitrile, and clofibrate) or the general P450 inhibitor 1-aminobenztriazole; induction of P4501A,

6 The cytochrome P450 inhibitor 1-benzylimidazole did not affect SAC, SBC

7 inhibitor) nor ethoxyresorufin (a cytochrome P450 inhibitor) altered the 86Rb uptake response to PDBu

8 response were ameliorated by the cytochrome P450 inhibitor aminobenzotriazole.

9 he tightest-binding azaheterocycles found in P450 inhibitors and could offer new avenues for inhibito

10 be required for toxicity (no protection with P450 inhibitors and no detectable inorganic fluoride rel

11 actions, the development of isoform-specific P450 inhibitors, and the engineering of novel oxidative

12 -octadecynoic acid (17-ODYA, 10(-5) mol/L; a P450 inhibitor) attenuated maximal dilation to AA (49+/-

13 of intracerebral (ic) microinjections of the P450 inhibitor CC12 were determined on morphine antinoci

14 rats injected with anti-Fx1A, the cytochrome P450 inhibitor cimetidine blocked an increase in catalyt

15 xidase, and aminobenzotriazole, a cytochrome P450 inhibitor, decreased free radical formation from fo

16 onazole (10(-5) mol/L, a chemically distinct P450 inhibitor) further reduced the dilation to AA in th

17 does the fact that polycyclic azoles (known P450 inhibitors) have potent anti-mycobacterial effects.

18 llular dialysis with 2 mM cAMP abolished the P450 inhibitor-induced suppression of ICa.

19 0.8 microM) compared with the broad spectrum P450 inhibitor ketoconazole and the retinoid mimetic R11

20 The azole-based P450 inhibitor ketoconazole is used to treat fungal infe

21 concentration-dependent and inhibited by the P450 inhibitors, ketoconazole and clotrimazole with IC(5

22 bitor diphenyleneiodonium chloride or by the P450 inhibitor metyrapone, providing evidence of its dep

23 HPETE, and pretreatment with the cyctochrome P450 inhibitor, miconazole, blocked the formation of the

24 biosynthesis, and clotrimazole, a cytochrome P450 inhibitor, significantly reduced ICa in both wild-t

25 , econazole and miconazole, which are potent P450 inhibitors, significantly suppressed cardiac ICa.

26 The cytochrome P450 inhibitors, SKF 525A and miconazole, significantly

27 ): (1) Control, (2) l-NAME, (3) a cytochrome P450 inhibitor, sulfaphenazole, and (4) sulfaphenazole +

28 entified six triazole fungicides, all fungal P450 inhibitors, that dock in the catalytic site.

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