1  electron transfer from NADPH to P450C17 and P450C21.

2 17, 17-hydroxylase/17,20-lyase) and CYP21A2 (P450c21, 21-hydroxylase) catalyze progesterone hydroxyla

3 perplasia with apparent combined P450C17 and P450C21 deficiency in affected children.

4 perplasia with apparent combined P450C17 and P450C21 deficiency is associated with accumulation of st

5 ne that overlaps the steroid 21-hydroxylase (P450c21) gene in the HLA locus on chromosome 6p21.3.

6                The CYP21 gene, which encodes P450c21, the adrenal steroid 21-hydroxylase needed for g