ライフサイエンスコーパス: PEG

1 PEG conjugation reduces protein interactions with the ol

2 PEG hydrogels with controllable thickness and elastic mo

3 PEG-carbonate HPs 24 and 25 were found to have potent an

4 PEG-dendron amphiphiles can serve as powerful tools for

5 PEG-disulfide appears to selectively functionalize the e

6 PEG-PTX 20k showed equivalent efficacy as PEG-PTX 6k del

7 PEG-stabilized particles had smaller relative losses at

8 tissue penetration between the 62 and 110nm PEG-coated NPs, as well as between PEG-coated and uncoat

9 Apelin-36-[L28C(30kDa-PEG)] is 10,000-fold less potent than apelin-36 at activ

10 Apelin-36-[L28C(30kDa-PEG)] provides a starting point for the development of d

11 fically, a series of cucurbit[7]uril (CB[7])-PEG conjugates are shown to substantially increase the s

12 cluded in the NMA (PEG N = 9, PEG + E N = 8, PEG versus PEG + E N = 2; involving 2247 patients).

13 reating cells with polyethylene glycol 8000 (PEG) during infection.

14 studies were included in the NMA (PEG N = 9, PEG + E N = 8, PEG versus PEG + E N = 2; involving 2247

15 detached portion of the internal bumper of a PEG tube in the gastric lumen after a challenging gastro

16 hronic HCV infection who were treated with a PEG-IFN and ribavirin.

17 glycol)-block-poly(lactic-co-glycolic acid) (PEG-PLGA) copolymers have been used successfully for tar

18 ylene glycol)-poly(lactic-co-glycolic acid) (PEG-PLGA) microparticles were engineered to release TGF-

19 ADI-PEG 20 induced general control nonderepressible 2-depend

20 ADI-PEG 20 treatment of mice bearing contralateral flank UM-

21 sive bladder cancer and is targetable by ADI-PEG 20.

22 stable disease or better could continue ADI-PEG 20 monotherapy until disease progression or withdraw

23 Purpose Pegylated arginine deiminase (ADI-PEG 20) depletes essential amino acid levels in arginino

24 ing enzyme pegylated arginine deiminase (ADI-PEG 20).

25 mended dose, safety, and tolerability of ADI-PEG 20, cisplatin, and pemetrexed in patients with ASS1-

26 cells showed preferential sensitivity to ADI-PEG 20, evidenced by decreased colony formation, reduced

27 vents (all grade 1 or 2) were related to ADI-PEG 20.

28 mend a dose for future studies of weekly ADI-PEG 20 36 mg/m(2) plus three-weekly cisplatin 75 mg/m(2)

29 s (five MPM, four NSCLC) received weekly ADI-PEG 20 doses of 18 mg/m(2), 27 mg/m(2), or 36 mg/m(2), t

30 Gastric juice and sputa from sixteen adult PEG fed CF patients and five replaced PEG tubes were stu

31 yethylene glycol based chain transfer agent (PEG-CTA) and hydrophilic acrylonitrile monomers in water

32 Pegylated interferon alfa (PEG-IFNalpha) is effective in only 25%-30% of patients a

33 Unlike ALG, PEG resists osmotic stress, hence we generated hybrid mi

34 and microscopy, we studied four amphiphilic PEG-dendron hybrids and their self-assembled micelles in

35 (19.3 +/- 7.4 vs 7.3 +/- 5.9; p = 0.001) and PEG/PG (19.3 +/- 7.5 vs 7.9 +/- 8.2; p = 0.001) respecti

36 higher latent heats than that of PEG/DI and PEG/EVM.

37 s no efficacy difference between PEG + E and PEG (0.1, 95 % Crl -1.1, 1.2) and there were no differen

38 0 dose-response curves for GCSF, GCSF-Fc and PEG-GCSF were 37 +/- 12 pM, 75 +/- 13.5 pM and 46 +/- 5.

39 The bioactivities of GCSF-Fc and PEG-GCSF were similar to native GCSF using the mouse M-N

40 We conclude that gastric juice and PEG-tubes may be a potential source of MABSC isolates in

41 ree PEG (OH-PEG3K-NH2 and CH3-PEG5K-NH2) and PEG-like molecule (CH3-PEG5K-FITC, CH3-PEG5K-SHPP, and C

42 anscript level is highly induced by salt and PEG-induced drought stress in both shoots and roots in b

43 on, although the OsNHX1 response to salt and PEG-induced drought stress in either shoots or roots was

44 nes are differentially regulated by salt and PEG-induced drought stress in two rice genotypes, Nippon

45 fungi grew from all gastric juice, sputa and PEG samples.

46 Our data indicate that both MEGs and PEGs in rice regulate nutrient metabolism and endosperm

47 t assay (ELISA) for PEG by tethering an anti-PEG antibody (AGP3) via tethers with different dimension

48 Anchoring anti-PEG antibodies on cells via variable-length tethers for

49 and 192 subjects with anti-PEG IgM and anti-PEG IgG, respectively, and 596 controls.

50 However, the current methods to detect anti-PEG abs are tedious and usually lack quantification.

51 itive, and reliable technique to detect anti-PEG abs is highly desired in both research and clinic se

52 antibodies and certain patients develop anti-PEG antibody during treatment with PEGylated medicines,

53 y, and with 492 subjects without either anti-PEG IgM or IgG as controls.

54 levels, and Ab isotype of pre-existing anti-PEG Ab remain poorly understood.

55 e healthy individuals have pre-existing anti-PEG antibodies and certain patients develop anti-PEG ant

56 ater than that of 293T cells expressing anti-PEG antibodies with uniform tether lengths.

57 orm genome-wide association studies for anti-PEG IgM and IgG responses in Han Chinese with 177 and 14

58 40 individuals, defined as positive for anti-PEG IgM and IgG responses, respectively, and with 492 su

59 ding pre-existing and treatment-induced anti-PEG Abs.

60 owerful method to prescreen and monitor anti-PEG abs in the patients before or after they receive tre

61 iosensor technique for the detection of anti-PEG abs and compared three PEG surface chemistries.

62 The detection of anti-PEG abs directly from diluted blood serum was achieved w

63 To better understand the nature of anti-PEG immunity, we summarize a number of clinical reports

64 specifically recognize and bind to PEG (anti-PEG Abs), including both pre-existing and treatment-indu

65 consisting of 211 and 192 subjects with anti-PEG IgM and anti-PEG IgG, respectively, and 596 controls

66 chain (IGH) locus to be associated with anti-PEG IgM response at genome-wide significance (P = 2.23 x

67 d find the IGH locus is associated with anti-PEG IgM.

68 PEG-PTX 20k showed equivalent efficacy as PEG-PTX 6k delivered at a 2.5-fold higher dose, suggesti

69 urified from E. coli was not as efficient as PEG-GCSF in treating neutropenic rats.

70 ependent on molecular weight of the attached PEG chain.

71 Both CMD and CMD-b-PEG decreased the charge of alpha-lac below pH 5.5 and l

72 Complexes of alpha-lac/CMD-b-PEG formed at pH values near pH 6, while alpha-lac/CMD c

73 PLGA-b-PEG copolymer was synthesized and characterized by (1)H

74 o the brain via ascorbic acid grafted PLGA-b-PEG nanoparticles (NPs) using SVCT2 transporters of chor

75 to the brain by ascorbic acid grafted PLGA-b-PEG NPs is a promising approach.

76 PLGA-b-PEG NPs with desirable size, polydispersity, and drug lo

77 Additionally, PLGA-b-PEG-Asc NPs resulted in significantly higher biodistribu

78 c and sustained action by drug loaded PLGA-b-PEG-Asc NPs than free drugs and drug loaded plain PLGA a

79 r the conjugation with ascorbic acid (PLGA-b-PEG-Asc) to facilitate SVCT2 mediated transportation of

80 In summary, a PLGA-b-PEG-b-PLGA sol-gel has loading and release capacities fo

81 ck-poly(d,l-lactic-co-glycolic acid) (PLGA-b-PEG-b-PLGA) thermosensitive gel (g-E).

82 PLGA-b-PEG-NH2 and PLGA-b-mPEG NPs were prepared by nanoprecipi

83 and 110nm PEG-coated NPs, as well as between PEG-coated and uncoated NPs.

84 There was no efficacy difference between PEG + E and PEG (0.1, 95 % Crl -1.1, 1.2) and there were

85 mes, and o(LA)n-PTX improves PTX delivery by PEG-b-PLA micelles, providing a strong justification for

86 data, although limited to 3 subjects, of C34-PEG-4-Chol suggest continuing evaluation of this agent a

87 ethylene glycol)-poly(epsilon-caprolactone) (PEG-PCL, PECL) to get DA-TAT-PECL.

88 nti-fouling effect conferred by the carboxyl-PEG layer, we could directly detect as little as 10fM of

89 olyethyleneglycolylated human truncated CBS (PEG-CBS).

90 These studies support the use of CC (PEG MG) for islet encapsulation and transplantation in c

91 han that of naked islets, we showed that CC (PEG MG) islets from fully MHC-mismatched Balb/c mice sup

92 other composed of sphingomyelin/cholesterol/PEG (55/40/5; mol/mol) (CPD100 PEGLi).

93 At the gene body of con-PEGs (constitutively expressed PEG), H3K27me3 and H3K36m

94 non-covalent approach was used to conjugate PEG bearing a terminal cholanic moiety (mPEG5kDa-cholane

95 rm, (ii) polyethylene glycol-PLGA conjugate (PEG-PLGA, p) to help maintain an appropriate level of po

96 We also conjugated PEG aldehyde to GCSF to make PEG-GCSF.

97 Amphiphilic arrays containing PEG-substituted BODIPY and chlorins or bacteriochlorins

98 to therapeutics modified with or containing PEG.

99 Using a bifunctional SAM containing PEG moieties and a tethered redox thiol, both markers ar

100 ion, then coated by anionic block copolymer, PEG-polyglutamic acid (double-coat (DC) nanozyme).

101 In addition, dendritic PEG cosolvents were employed in the phase separation str

102 ue compared to nanoparticles without a dense PEG corona following local administration by either manu

103 e trapping in the brain owing to their dense PEG coating, which was critical to achieving widespread

104 ycol (PEG-SH) with or without PEG disulfide (PEG-S-S-PEG), the three-regime kinetics of the polymer b

105 Ratcheted reciprocating motion of a DNA/PEG copolymer threaded through a single alpha-hemolysin

106 arboxyl-propylene carbonate-graft-dodecanol; PEG-PCD) to prepare micelles.

107 educed dose PEG + LB compared with full dose PEG + LB.

108 mcg) vs placebo and efficacy of reduced dose PEG + LB compared with full dose PEG + LB.

109 y-propyl)-trimethylammonium/Cholesterol/DSPE-PEG-anisamide aminoethyl.

110 r matrix (Matrigel; MG) islet encapsulation (PEG MG) to improve capsule immunoisolation by decreasing

111 Exchanging PEG tubes may result in complications due to inexperienc

112 We refined the CC composition and explored PEG and islet-like extracellular matrix (Matrigel; MG) i

113 e body of con-PEGs (constitutively expressed PEG), H3K27me3 and H3K36me3 were specifically deposited

114 ion of the nanodot molecular occupancy by Fc-PEG chains can be reliably quantified, evidencing that a

115 nt pre-treatment predictors of SVR following PEG-IFN-based therapy in HCV genotype 1 patients.

116 ncipal stratification and selection bias for PEG treatment through generalized propensity scores.

117 he binding capacity of hybrid-type cells for PEG-like molecules (CH3-PEG5K-FITC (FITC = fluorescein i

118 nzyme-linked immunosorbent assay (ELISA) for PEG by tethering an anti-PEG antibody (AGP3) via tethers

119 A unique signature for PEGs was observed, where the active H3K4me4 and H3K36me3

120 inding capacity and detection limit for free PEG and PEGylated molecules.

121 The detection limit of free PEG (OH-PEG3K-NH2 and CH3-PEG5K-NH2) and PEG-like molecu

122 e, high-capacity method for quantifying free PEG and PEGylated molecules.

123 cyclodextrin poly(ethylene glycol) (PPP-CD-g-PEG) combined with gold nanoparticle (AuNP) conjugates a

124 ice and percutaneous endoscopic gastrostomy (PEG) feeding devices might yield MABSC isolates.

125 Percutaneous endoscopic gastrostomy (PEG) is an effective and safe mode of enteral nutrition

126 gh local injection, the membrane anchored GC-PEG-PpIX enables strong physical association with tumor

127 mulation and prolonged tumor retention of GC-PEG-PpIX were realized after intravenous injection, whic

128 The as-prepared GC-PEG-PpIX can self-assemble into core-shell nanoparticles

129 , when encountering plasma membranes, the GC-PEG-PpIX NPs can disassemble and stably attach to plasma

130 es (MEGs) and 95 paternally expressed genes (PEGs), which were associated with miniature inverted-rep

131 o-localized with paternally expressed genes (PEGs), while endosperm-specific maternally expressed gen

132 we showed that CC using polyethylene glycol (PEG) and alginate (ALG) was not immunoisolating because

133 nse surface coatings of polyethylene glycol (PEG) and are loaded with cisplatin (CDDP) could be deliv

134 ds of mineral-supported polyethylene glycol (PEG) as form-stable composite phase change materials (CP

135 tissue penetration; ii) polyethylene glycol (PEG) chains to prolong blood circulation; and iii) sharp

136 s based on (i) flexible polyethylene glycol (PEG) conjugates and (ii) rigid self-assembled DNA.PNA co

137 tion and removal of the polyethylene glycol (PEG) continuous phase (using an organic solvent not pene

138 nd that possess a dense polyethylene glycol (PEG) corona that prevents them from being trapped by adh

139 ferrocene (Fc) labeled polyethylene glycol (PEG) disulfide chains.

140 charged, non-spherical polyethylene glycol (PEG) hydrogel NPs by endothelial cells (ECs) cultured in

141 iously, we engineered a polyethylene glycol (PEG) hydrogel-based subunit vaccine for the delivery of

142 olymerization between a polyethylene glycol (PEG) macroreversible addition-fragmentation chain-transf

143 AE conjugated with 5kDa polyethylene glycol (PEG) molecules (PBAE-PEG) rapidly penetrate healthy brai

144 apeutic molecules, (ii) polyethylene glycol (PEG) outer shell to prolong blood circulation; and (iii)

145 ification of AMQDs with polyethylene glycol (PEG) significantly enhanced both biocompatibility and st

146 Since traditional polyethylene glycol (PEG) surface layer interferes with the cell-NP interacti

147 Conjugation of polyethylene glycol (PEG) to therapeutic molecules can improve bioavailabilit

148 liposomes covered with polyethylene glycol (PEG) were synthesized using the PR_b peptide that binds

149 porphyrin IX (PpIX) and polyethylene glycol (PEG) with glycol chitosan (GC).

150 ion in combination with polyethylene glycol (PEG)) gives comparable activity concentration values.

151 the molecular weight of polyethylene glycol (PEG), 20kDa or 40kDa, had a moderate effect on the resid

152 that specifically bind polyethylene glycol (PEG), a biocompatible polymer routinely used in protein

153 segments: a hydrophilic polyethylene glycol (PEG), a bortezomib-conjugating intermediate, and a dendr

154 based, for example, on polyethylene glycol (PEG), N-(2-hydroxypropyl)methacrylamide (HPMA), polymeri

155 coated NPs, 40 nm sized polyethylene glycol (PEG)- and citrate-coated NPs, and 60 nm sized PVP- and c

156 tocytes into engineered polyethylene glycol (PEG)-based nanoporous human ectopic artificial livers (H

157 of reinforcing ALG with polyethylene glycol (PEG).

158 hout pre-conjugation to polyethylene glycol (PEG).

159 solutions of thiolated polyethylene glycol (PEG-SH) with or without PEG disulfide (PEG-S-S-PEG), the

160 e pharmacokinetics of poly(ethylene glycol) (PEG) and PEGylated molecules is critical for PEGylated d

161 ting and induced anti-poly(ethylene glycol) (PEG) antibodies (abs) have been shown to be related with

162 variations of the PLA-poly(ethylene glycol) (PEG) based precision-polyester (P2s) platform, permittin

163 The influence of the poly(ethylene glycol) (PEG) chain length on the performance of water-soluble, p

164 chain length and with poly(ethylene glycol) (PEG) changing certain physicochemical properties in a pr

165 Poly(ethylene glycol) (PEG) is a widely used biocompatible polymer.

166 SOD1 with polycation poly(ethylene glycol) (PEG)-polylysine (single-coat (SC) nanozyme), we introduc

167 mineral particles in poly(ethylene glycol) (PEG)/dextran (Dx) aqueous two-phase systems (ATPS).

168 pounds identified were polyethylene glycols (PEGs), polypropylene glycols (PPG), linear alkyl-ethoxyl

169 th of a hydrophobic chain on the hydrophilic PEG chain induces self-assembly of polymeric amphiphiles

170 capsulate hydrophobic drugs, the hydrophilic PEG shell provides excellent water dispersity.

171 , and (4) isocoumarin synthesis using Ru(II)/PEG as a recyclable catalytic system via ortho-C-H activ

172 nt with miRs packaged in ESTA-MSV but not in PEG/PEI reduced atherosclerotic plaque size.

173 ribed to precisely tune stress relaxation in PEG networks formed from mixtures of two different pheny

174 uggesting that genetics might play a role in PEG immunogenicity.

175 dies of PEG-density revealed that increasing PEG density enhanced NP diffusion and that PEG density b

176 by the following strategies: peg-interferon (PEG-IFN)/ribavirin (RBV) for 48 weeks, PEG-IFN/RBV plus

177 treatment responses to pegylated interferon (PEG-IFN)-based therapy in patients with chronic HCV infe

178 9)Zr chelator desferroxamine B via a 3.4-kDa PEG linker.

179 y for integrin-targeting, as well as a 5 kDa PEG chain that passivates the construct and enables its

180 rchitectures, namely mono-LA-PEG and bis(LA)-PEG.

181 fferent ligand architectures, namely mono-LA-PEG and bis(LA)-PEG.

182 The series of linear PEGs in the molar mass range of only a few thousand to 5

183 lic acid (FTA) loaded (lipid-cationic) lipid-PEG-PLGA hybrid nanoparticles (HNPs) after IN applicatio

184 ean +/- standard deviation of tumor-to-liver PEG-HAuNS uptake ratios at 1 hour and 24 hours, respecti

185 Here we show that maintaining PEG in culture medium increases the rate of infection by

186 also conjugated PEG aldehyde to GCSF to make PEG-GCSF.

187 The maximum PEG absorption of diatomite (DI), expanded perlite (EP)

188 Methoxy-PEG (mPEG) 5k was found to have the best performance.

189 we generated hybrid microcapsules by mixing PEG and ALG (MicroMix) or by coating ALG capsules with a

190 a PEGylated protein (PegIntron) and multiarm PEG macromolecules (eight-arm PEG20K-NH2 and eight-arm P

191 by coating ALG capsules with a 15 +/- 2 mum PEG layer (Double).

192 Further experiments demonstrate that nGO-PEG indeed provokes cytokine secretion by enhancing inte

193 hat PEGylated graphene oxide nanosheets (nGO-PEGs) stimulate potent cytokine responses in peritoneal

194 simulations support a mechanism by which nGO-PEGs preferentially adsorb onto and/or partially insert

195 Nineteen studies were included in the NMA (PEG N = 9, PEG + E N = 8, PEG versus PEG + E N = 2; invo

196 psules were comparable to Micro, addition of PEG to ALG in MicroMix capsules improved engraftment of

197 pecificity was achieved with the addition of PEG to the antibody-functionalized bead surface, highest

198 The aims to assess adequacy of PEG preparation with addition of single dose LB (24mcg)

199 thality, while therapeutic administration of PEG-IFNlambda potently suppresses these effects.

200 lysis by observing differing arrangements of PEG and water molecules within the active site.

201 On the basis of the binding of PEG molecules to Rv3802, we identified its lipid-binding

202 First, triblock copolymers of PEG-CNA-PLGA are synthesized and then formulated into po

203 The large effect of PEG 20 on cold denaturation can be explained by a change

204 However, the effect of PEG architecture and the manner in which the PEG compone

205 strates a significant and positive effect of PEG treatment, particularly when time of treatment is in

206 tance requirements of HA, the flexibility of PEG scaffolds is too high to raise the effective concent

207 markers for predicting the immunogenicity of PEG and efficacy of PEGylated therapeutics.Some individu

208 d stable and low fouling by incorporation of PEG moieties.

209 s models exposed the inherent limitations of PEG-based spacers.

210 the survivor average causal effect (SACE) of PEG on BMI, a surrogate outcome measure of nutrition and

211 We report that the oxidation state of PEG-thiol is key to anisotropic silica coating, with the

212 Studies of PEG-density revealed that increasing PEG density enhance

213 esults suggest the preferential targeting of PEG-HCCs to T lymphocytes as a novel approach for T lymp

214 as slightly higher latent heats than that of PEG/DI and PEG/EVM.

215 ng features of this synthesis are the use of PEG-400 as a green solvent for the (3 + 2) annulation re

216 The distribution of PEGs, PPGs, and TIPA and their ubiquitous presence in ou

217 ly, one-third of MEGs and nearly one-half of PEGs were associated with grain yield quantitative trait

218 Oligolysine-PEG-stabilized DNA nanostructures survive uptake into en

219 ented by coating instead with an oligolysine-PEG copolymer, enabling up to a 1,000-fold protection ag

220 Thus, oligolysine-PEG is a one-step, structure-independent approach that p

221 The attachment of a hydrophobic block on PEG leads to self-assembly and formation of spherical mi

222 rary of 1296 different tetramer compounds on PEG-polystyrene beads.

223 ate ionic strengths (1-20%) that depended on PEG length.

224 ed to reliably deposit side silica shells on PEG-disulfide functionalized gold nanorods.

225 had MABSC isolated in their gastric juice or PEG tube.

226 ral particles through ultracentrifugation or PEG precipitation, was PEG independent and much more eff

227 and heavily PEGylated polyaspartic acid (PAA-PEG), was highly stable, provided extended drug release,

228 tic acid-modified poly(ethylene glycol) (Pal-PEG) are combined with a tailored drug binding peptide t

229 Da polyethylene glycol (PEG) molecules (PBAE-PEG) rapidly penetrate healthy brain parenchyma and orth

230 Transgene expression with the PBAE/PBAE-PEG blended nanocomplexes (DNA-loaded brain-penetrating

231 ing polyethylenimine-polyethyleneglycol (PEI-PEG) tethered to the PSMA ligand, 2-[3-(1, 3-dicarboxy p

232 We designed a nonviral vector, PEI-PEG-DUPA (PPD), comprising polyethylenimine-polyethylene

233 lycol)-b-poly(lactic-co-glycolic acid); PLGA-PEG-PLGA) for increasing the retention of RNA nanopartic

234 ing is achieved by coating FDA-approved PLGA-PEG NP with the peptide sequence RGD, which binds with h

235 d) (PLGA) and PLGA-polyethylene glycol (PLGA-PEG) polymers to generate sub-100nm nanoparticles with m

236 intramucosal and lymph-node delivery of PLGA-PEG nanoparticles was demonstrated in a porcine model.

237 Next, the biocompatible polymers PLGA-PEG-A were synthesized and used as base to conjugate DCL

238 en further equipped with polyethyleneglycol (PEG) and the delivery efficiency of the copolymer was te

239 ed in polyethylene glycol-polyethyleneimine (PEG/PEI) nanoparticles and loaded into ESTA-MSV micropar

240 targeted theranostic nanoplatform (Porphyrin-PEG Nanocomplexes, PPNs).

241 lerolactone-poly(ethylene glycol) (PAMAM-PVL-PEG).

242 ial replacement of pharmaceutically relevant PEGs by alternative macromolecules offering a suite of s

243 adult PEG fed CF patients and five replaced PEG tubes were studied.

244 red, low dispersity poly(ethylene glycols)s (PEGs), also known as poly(ethylene oxide)s (PEOs) depend

245 G-SH) with or without PEG disulfide (PEG-S-S-PEG), the three-regime kinetics of the polymer brush for

246 to the boron, whereas in the second series, PEG substituents are attached to the aryl at the meso po

247 In particular, larger rod- and disk-shaped PEG NPs show more uptake than smaller ones, opposite to

248 ers from that reported for uptake of similar PEG NPs by ECs in a static culture, where the smaller di

249 The UCNP-(CD/Azo)-siRNA/PEG NPs with both GE11 and TH peptides display a high le

250 onalized with PEG (i.e., UCNP-(CD/Azo)-siRNA/PEG NPs), targeting ligands (i.e., EGFR-specific GE11 pe

251 Most MEGs and some PEGs were expressed specifically in the endosperm.

252 (LB) could improve the adequacy of standard PEG preparation & reduce requirement.

253 ated NPs were more persistent in tumors than PEG-coated NPs, in agreement with the in vitro results.

254 g PEG density enhanced NP diffusion and that PEG density below a critical value led to adhesion of NP

255 tematically investigated to demonstrate that PEG tuning can provide control over micrometastasis trac

256 We postulate that PEG-lipid based nanocarriers can serve as bioactive drug

257 , crystallization fraction results show that PEG/EP has slightly higher latent heats than that of PEG

258 The results show that PEG/EP has the best thermal and chemical stability after

259 The PEG-CBS treatment prevented an otherwise fatal liver dis

260 The PEG-coated AMQDs showed a PTCE of 45.5 %, which is highe

261 We adjusted two methods of DNA delivery: the PEG-mediated delivery and the biolistic bombardment base

262 By re-designing the PEG scaffold to be macroporous, we demonstrate the facil

263 Dynamic responses of the PEG-DA microcantilever can be obtained in a range of IR

264 ELISA assay revealed the PEG-GCSF had the longest plasma circulation (>72 h), fol

265 rough both in vitro and in vivo studies, the PEG-coated AMQDs demonstrated notable NIR-induced tumor

266 ibe a PEGylated colistin prodrug whereby the PEG is attached via a cleavable linker (col-aaPEG) intro

267 PEG architecture and the manner in which the PEG component interferes with the hybridization of the o

268 A strands do not get encapsulated within the PEG-CNA-PLGA nanoparticles.

269 one had the same strain isolated from their PEG tube and sputum.

270 th poly(ethylene glycol) methyl ether thiol (PEG-thiol) prior to silica coating, but such results hav

271 uch as four-arm poly(ethylene glycol)-thiol (PEG-SH) via chemisorption.

272 cts of surface modification with small thiol-PEG ligands on protein adsorption are also demonstrated.

273 detection of anti-PEG abs and compared three PEG surface chemistries.

274 n and embryo size, whereas mutation of three PEGs reduced starch content and seed fertility.

275 stem that specifically recognize and bind to PEG (anti-PEG Abs), including both pre-existing and trea

276 site-specific conjugation of biomolecules to PEG-coated surfaces.

277 t and DNA via copper-free click chemistry to PEG-coated substrates and a strong but reversible strept

278 ut reversible streptavidin-biotin linkage to PEG-coated AFM tips enhanced data quality and throughput

279 -treatment predictive marker for response to PEG-IFN-based therapy in chronic HCV genotype 1 infectio

280 ss and the OsNIN-like4 in roots subjected to PEG was mainly up-regulated in Hasawi, indicating that t

281 rther studies would be required to translate PEG-GIRLRG peptide into the clinic.

282 s involving linear, Y-shaped, and brush-type PEG.

283 the mesophases of the G-quadruplexes, under PEG-induced crowding conditions, with the corresponding

284 3) shrinking microflowers into iDR-NCs using PEG-grafted cationic polypeptides, and (4) physically lo

285 he NMA (PEG N = 9, PEG + E N = 8, PEG versus PEG + E N = 2; involving 2247 patients).

286 by chemotherapy (dexamethasone, vincristine, PEG-asparaginase) resulted in significantly improved sur

287 ltracentrifugation or PEG precipitation, was PEG independent and much more efficient in HepaRG cells

288 eron (PEG-IFN)/ribavirin (RBV) for 48 weeks, PEG-IFN/RBV plus boceprevir (BOC) or telaprevir (TEL) fo

289 A complementary to the CNA sequence, whereas PEG-PLGA alone shows minimal DNA loading, and non-comple

290 Acylation with PEG containing five ethylene glycol units led to the lar

291 red by substituting the fine aggregates with PEG/EP CPCMs.

292 first series of arrays contains BODIPYs with PEG substituents attached to the boron, whereas in the s

293 here was no significant change compared with PEG-Lipo-Dox.

294 Block copolymers with PEG as a nonresponsive water-soluble block can self-asse

295 siRNA complexes are also functionalized with PEG (i.e., UCNP-(CD/Azo)-siRNA/PEG NPs), targeting ligan

296 at early treatment of patients with HCU with PEG-CBS may prevent clinical symptoms of the disease pos

297 to neutropenic rats, the group injected with PEG-GCSF showed the highest and fastest recovery of neut

298 eucovorin rescue or escalating dose MTX with PEG asparaginase without leucovorin rescue.

299 before or after they receive treatment with PEG-containing drugs.

300 polyethylene glycol (PEG-SH) with or without PEG disulfide (PEG-S-S-PEG), the three-regime kinetics o