ライフサイエンスコーパス: PM

1 PM and soil samples were analyzed for 15 elements using

2 PM arriving in the airways could potentially interact wi

3 PM association is mediated, in part, by farnesylation of

4 PM depletion of either phosphatidylinositol 4-phosphate

5 PM is associated with increased proinflammatory cytokine

6 PM localization of Kit(mut) is not required for its sign

7 PM size distributions showed unimodal peaks for both MGO

8 PM sub-compartmentalization in domains is thought to orc

9 PM was isolated from the intact leaves and size fraction

10 PM-recruited GRK2ct-KERE inhibits lysophosphatidic acid-

11 ence at 5:00 AM (lean vs. OW/OB) and at 5:00 PM (OW/OB vs. T2DM).

12 i-angiogenic protein thrombospondin-1 (TSP-1 PM).

13 This percentage varied by operation: PM 15%, PM SLNB 25%, LC 33%, LIH 15%, and IH 31%.

14 Pollutants measured included PM2.5 (PM = particulate matter), PM10, ultrafine particles, bla

15 of patients undergoing each operation: PM 5, PM SLNB 10, LC 15, LIH 15, and IH 15.

16 iagnosed as having 14 cancers occurring as a PM or SPM were included.

17 x16 and msgn1, thereby committing cells to a PM fate.

18 8.3% lower for older adults compared with a PM at the same age.

19 uxin-mediated expansion growth by activating PM H(+)-ATPases to facilitate apoplast acidification and

20 g patterns of modulatory effects could allow PMd and PMv to play distinct functions for the control o

21 odulation provide a substrate that may allow PMd and PMv to carry distinct functions for the preparat

22 (1) deplete ER cholesterol without altering PM or overall cellular cholesterol levels; (2) demonstra

23 ight into an early mechanism for how ambient PM increases the susceptibility of the airways to bacter

24 usive picture of the ROS activity of ambient PM.

25 Ten ambient PM samples collected from an urban site were analyzed, a

26 er visual areas, AL (anterolateral area) and PM (posteromedial area), display distinct visual propert

27 tify major potential PM 2.5 contributors and PM 2.5 transport pathways of a network of 189 cities in

28 work focuses on the diversity of the DOM and PM types investigated.

29 Changes in other gas and PM emissions, as well as impacts on acid and nutrient de

30 In both the RAW264.7 macrophage and PM in vitro models, HSV-1 replication in M1 macrophages

31 data on geographic distance, mountains, and PM 2.5 concentrations.

32 The largest reductions for ozone and PM occur in urban areas due to lower mobile source emiss

33 Dbx1 microdomain, at the expense of STN and PM populations.

34 for genomic instability, and both SCNAs and PMs could be thought to associate with distinct signatur

35 combustion and is a source of anthropogenic PM with worldwide health relevance.

36 The nano-assembly PM-GSH-CuNCs was applied for the selective detection of

37 Advantageously, the nano-assembly PM-GSH-CuNCs was chemically adsorbed over the cellulosic

38 is highly suitable to be used in atmospheric PM monitoring studies and that morphological and element

39 osited particles as indicator of atmospheric PM concentration and composition.

40 uxin activates plasma membrane H(+)-ATPases (PM H(+)-ATPases) to facilitate cell expansion by both lo

41 In analyses considering cumulative average PM exposure, the comparing the top to the bottom quintil

42 The difference between PM+ and EUC in the change from baseline to 3 months on t

43 outcomes, for WHODAS the difference between PM+ and EUC in the change from baseline to 3-month follo

44 t apically targeted cargo delivery, for both PM-destined and secretory cargo, providing the first evi

45 We found that single units in both PMd and PMv encode the kinematics of both reaching and g

46 We found that single cells in both PMd and PMv encode the kinematics of both reaching and g

47 rays to record unit-spiking activity in both PMd and PMv simultaneously while rhesus macaques engaged

48 ion and increased tail unsaturation in brain PM) appear to have opposite, yet complementary, influenc

49 of MLKL results in the generation of broken, PM "bubbles" with exposed PS that are released from the

50 Carbonaceous PM emission and SOA formation is markedly higher from ga

51 ide a systematic examination of carbonaceous PM emissions and parameterisation of SOA formation from

52 lations to bulk measurements of carbonaceous PM including organic carbon, elemental carbon, and water

53 singly dominate vehicular total carbonaceous PM, though older non-DPF-equipped diesels will continue

54 atic interactions between negatively charged PM phospholipids and basic amino acids found in K-Ras4B

55 ed how acute depletion of negatively charged PM polyphosphoinositides (PPIns) from the PM alters the

56 ren or adults were exposed to fine or coarse PM in different seasons.

57 y higher than the risk of exposure to coarse PM in pathway activation.

58 fluence of playa exposure on PM composition, PM samples were collected during two seasons and at two

59 ells lacking efr3, which encodes a conserved PM scaffold for the phosphatidylinositol-4 kinase Stt4,

60 synthesis; and (3) determine that continuous PM-to-ER cholesterol transport allows ER to constantly m

61 The premotor cortex (PM) receives inputs from parietal cortical areas represe

62 these networks, the dorsal premotor cortex (PMd) has been implicated in the control of reaching move

63 grasp movements, the dorsal premotor cortex (PMd) has been implicated in the control of reaching move

64 NT The dorsal and ventral premotor cortices (PMd and PMv, respectively) are two specialized areas inv

65 The dorsal and ventral premotor cortices (PMd and PMv, respectively) each take part in unique aspe

66 For example, estimated daily PM intake and field-measurement-based global warming com

67 iated signalling components within dedicated PM nanodomains.

68 by visualising FLS2 and BRI1 within distinct PM nanodomains marked by specific remorin proteins and d

69 analysis of 951 experimental results on DOM-PM interactions, which enabled us to analyze and quantif

70 dy suggests that RASSF4 controls SOCE and ER-PM junctions through ARF6-dependent regulation of PM PI(

71 t for localization of STIM1 and E-Syts at ER-PM junctions, were reduced in RASSF4-knockdown cells.

72 phosphate homeostasis mediated by Nir2 at ER-PM junctions.

73 nesis plasmodesmata present such intimate ER-PM contact along the entire length of the pores that no

74 Endoplasmic reticulum-plasma membrane (ER-PM) junctions mediate crucial activities ranging from Ca

75 We focus in particular on the role of ER-PM contacts in nonvesicular lipid transport between the

76 ed that RASSF4 regulates the formation of ER-PM junctions and the ER-PM tethering function of extende

77 wever, the morphology and distribution of ER-PM junctions are not well characterized.

78 We envision that functions of ER-PM junctions can be differentially regulated through dyn

79 Spatial organization of ER-PM junctions may modulate the extent and location of the

80 to spatial distribution and stability of ER-PM junctions.

81 we reveal that the contact area of single ER-PM junctions is mainly oblong with the dimensions of app

82 Smaller ER-PM contacts occurred throughout dendrites, axons, and in

83 the formation of ER-PM junctions and the ER-PM tethering function of extended synaptotagmins E-Syt2

84 health risks associated with coarse and fine PM.

85 On the basis of AER values, the risk of fine PM exposure was relatively higher than the risk of expos

86 y average OP (OP(DTT)) in water-soluble fine PM at a central monitor site in Atlanta, Georgia, over e

87 rted previously, and are likely new QTLs for PM resistance in U.S. winter wheat.

88 peats (SSR) markers linked to three QTLs for PM resistance.

89 ity to PM are good sources of resistance for PM resistance breeding and the markers closely linked to

90 etermine the genomic regions responsible for PM resistance in a set of U.S. winter wheat and identify

91 s (CME) is a major internalization route for PM proteins.

92 trafficking route that beta-DG follows from PM to the nucleus.

93 and without the pre-extraction of PAHs from PM.

94 eet cholesterol needs, and subsequently from PM to regulatory domains of ER to suppress activation of

95 ible inhibitor of cholesterol transport from PM to endoplasmic reticulum (ER).

96 However, patterns of effects from PMd and PMv on the outputs of M1 have not been compared

97 , we studied the patterns of modulation from PMd within the same and in the opposite hemisphere on th

98 ctious virions by targeted modulation of Gag PM targeting.

99 pletion of PI(4,5)P2 completely prevents Gag PM targeting and assembly site formation.

100 A serving of whole milk from cows grazing PM had a higher content of saturated FA and branched-cha

101 alyzed included daytime, nighttime, and 24 h PM of <2.5 mum aerodynamic diameter (PM2.5) and total su

102 Our goals were to study how PMd within the same (i.e., ipsilateral or iPMd) and in t

103 l(II) (M; M = Ru, Os)-(porphinato)metal(II) (PM'; M' = Zn, Pt, Pd) molecular architecture (M-(PM')n-M

104 In PM women with early-stage BC receiving AIs, treatment wi

105 r C2A or C2C failed to rescue two defects in PM lipid homeostasis observed in E-Syts KO cells, delaye

106 To measure EPFRs in PM samples, high volume samplers are required and measur

107 ative content of oxygen centered radicals in PM with higher EPFR load.

108 e associated with a substantial reduction in PM-associated Cdc42 activity.

109 ote elongation growth and play a key role in PM H(+)-ATPase activation by inhibiting PP2C.D family pr

110 nuclear trafficking and having dual roles in PM and NE.

111 We recorded unit-spiking activity in PMd and PMv simultaneously while macaques performed a re

112 ting that the division of reach and grasp in PMd and PMv, respectively, cannot be made based on their

113 his classical division of reach and grasp in PMd and PMv, respectively, does not accurately reflect t

114 Inflammatory PM increased the detection rate of MMc among offspring o

115 e, and both noninflammatory and inflammatory PM increased the level of MMc.

116 om NM toxicology and use it to better inform PM health risk research and vice versa.

117 We investigated PM-AMP electrostatic interaction by attenuated total ref

118 d K-Ras is not as signaling-competent as its PM-bound form.

119 Leaf samples for laboratory PM analysis were collected from 188 randomly drawn sampl

120 Magmaris had significantly less PM-1-positive neutrophil and CD14-positive monocyte adhe

121 ULEV certified GDIs have a factor of 2 lower PM mass emissions than GDIs certified as ultralow-emissi

122 M' = Zn, Pt, Pd) molecular architecture (M-(PM')n-M), wherein high-oscillator-strength NIR absorptiv

123 S0) rate constants can be finely tuned in M-(PM')n-M compounds and (ii) demonstrate designs in which

124 the NIR spectral domain absorptivities of M-(PM')n-M chromophores far exceed those of classic coordin

125 scores the photophysical diversity of the M-(PM')n-M platform and presents a new library of long-wave

126 erials, this work demonstrates that these M-(PM')n-M systems realize near unit PhiISC at extraordinar

127 Prominent among MA-PM interactions is electrostatic attraction between the

128 64.7 macrophages and peritoneal macrophages (PM) on subsequent HSV-1 infection.

129 A mother's infection with placental malaria (PM) can affect her child's susceptibility to malaria, al

130 Pregnancy malaria (PM) is associated with a proinflammatory immune response

131 accompanied by an increase in particle mass (PM) by +266% (0.03 +/- 0.01 to 0.11 +/- 0.01 gPM/kg of f

132 ns (CSM) versus standard partial mastectomy (PM) in patients with breast cancer.

133 r (TRANSPHORM) projects: particulate matter (PM) </=2.5mum, </=10mum, and 2.5-10mum in diameter (PM2.

134 e composition of ambient particulate matter (PM) and its sources were investigated at the Salton Sea,

135 ble transition metals in particulate matter (PM) can generate reactive oxygen species in vivo by redo

136 k session, black carbon, particulate matter (PM) concentrations, ultrafine particles, and nitrogen di

137 Particulate matter (PM) deposited on Platanus acerifolia tree leaves has bee

138 Particulate matter (PM) in atmospheric pollution contains readily measurable

139 ined exposure to ambient particulate matter (PM) is a global cause of mortality.

140 Air particulate matter (PM) is a ubiquitous environmental exposure associated wi

141 ge, a factor of 2 higher particulate matter (PM) mass emissions than PFIs due to higher elemental car

142 comes, and the effect of particulate matter (PM) on the brain is beginning to be recognized.

143 erreactivity) and indoor particulate matter (PM) PM2.5.

144 Atmospheric particulate matter (PM) samples were collected from four ground-based sites

145 of prenatal exposure to particulate matter (PM) with newborn telomere length as reflected by cord bl

146 exposure to ambient air particulate matter (PM), and there is strong support for an important role o

147 ures attached to ambient particulate matter (PM).

148 e of toxicity of ambient particulate matter (PM).

149 arbon dioxide (CO2), and particulate matter (PM).

150 FGF-mediated PM induction in NMPs functions in tight coordination wit

151 zation of proteins from the plasma membrane (PM) allows for cell-surface composition regulation, sign

152 c protein assemblies at the plasma membrane (PM) and nuclear envelope (NE).

153 ell as well as nonapoptotic plasma membrane (PM) blebbing in this cellular motile process.

154 versible localization to ER-plasma membrane (PM) contacts is governed by phosphorylation and dephosph

155 ER-plasma membrane (PM) contacts were particularly abundant in cell bodies,

156 ticulum (SR) in response to plasma membrane (PM) excitation.

157 e investigate the impact of plasma membrane (PM) integrity on bacterial replication in different func

158 on molecule 1 (STIM1) to ER-plasma membrane (PM) junctions.

159 HIV-1 assembles at the plasma membrane (PM) of infected cells.

160 xert important control over plasma membrane (PM) Orai1 channels mediating store-operated Ca(2+) entry

161 (ER) proteins that bind the plasma membrane (PM) via C2 domains and transport lipids between them via

162 from within the cell to the plasma membrane (PM) where it formed STIM1-TRPC1 complexes, which then as

163 They are lined by the plasma membrane (PM), contain a strand of tubular endoplasmic reticulum (

164 n is best understood at the plasma membrane (PM), where it regulates cytoskeletal organization and ce

165 cytoplasmic surface of the plasma membrane (PM), where they are activated by cell surface G protein-

166 components, which exist in plasma membrane (PM)-localised protein complexes.

167 ccumulation of the normally plasma membrane (PM)-localized PEN3-GFP in endomembrane compartments.

168 is physically linked to the plasma membrane (PM).

169 es (SVs) fuse with the presynaptic membrane (PM) at specialized regions called active zones for synap

170 lectric immunosensor using purple membranes (PM) as the transducer, which contains photoactive bacter

171 nisms to ensure that their plasma membranes (PMs) are optimally supplied with cholesterol derived fro

172 6-diyl)bis(1-(4-methoxyphenyl) methanimine) (PM) on the corrosion of J55 and N80 steel in 3.5 wt.% Na

173 Wheat powdery mildew (PM), caused by Blumeria graminis f.

174 dy investigated the effects of pearl millet (PM) vs. cool-season pasture (CSP) on animal performance

175 ol transport allows ER to constantly monitor PM cholesterol levels, and respond rapidly to small decl

176 curring as first primary malignant neoplasm (PM) by age.

177 sid proteins (gag-pol mRNAs) to distinct non-PM subcellular locales, such as cytoplasmic vesicles or

178 pol mRNAs competent for Gag synthesis to non-PM membranes or the actin cytoskeleton severely reduced

179 The adsorption of PM on the J55 and N80 steel surface obeyed the Langmuir

180 lutants and undertook a detailed analysis of PM emissions from a very large crude oil carrier (VLCC)

181 A detailed analysis of PM revealed it was >90% organic carbon (OC) for both fue

182 0.1-0.2 mum) are redox active components of PM.

183 ffic intensity; and elemental composition of PM.

184 ource of PM mass and a controlling factor of PM composition.

185 espond to moderate effect sizes in favour of PM+ for GHQ-12 score (0.57, 95% CI 0.32-0.83) and PSYCHL

186 % CI 0.98-3.32, P = 0.001), all in favour of PM+.

187 3 (95% CI 1.86-4.79, P = 0.001) in favour of PM+.

188 erosol contributes a significant fraction of PM in the United States.

189 of PD associated with each size fraction of PM.

190 verage exposure to various size fractions of PM [PM10 (</=10mum microns in diameter), PM2.5 (</=2.5mu

191 flet of the plasma membrane preceded loss of PM integrity.

192 Second, transport pathways of PM 2.5 are revealed by another motif, which reflects tra

193 regulatory bodies support the principles of PM and its potential advantage over current treatment st

194 gradual implementation of the principles of PM within existing adult treatment algorithms for allerg

195 comparing the top to the bottom quintile of PM exposure was 0.85 [95% confidence interval (CI): (0.6

196 nctions through ARF6-dependent regulation of PM PI(4,5)P2 levels, pivotal for a variety of physiologi

197 Subsequent restoration of PM PI(4,5)P2 reinduced assembly site formation even in t

198 port the importance of playas as a source of PM mass and a controlling factor of PM composition.

199 Specification of PM 2.5 transmission characteristics is important for pol

200 vestigated the temporal response dynamics of PMd neurons across cortical layers and show stronger and

201 We also studied the adsorption of AMPs on PM.

202 udies into the effect of particle coating on PM-DOM interactions.

203 ardiograms (1986-2004), longitudinal data on PM<10 mum in diameter (PM10), and generalized estimating

204 t leaves and size fractionated, and EPFRs on PM quantified by electron paramagnetic resonance spectro

205 vestigate the influence of playa exposure on PM composition, PM samples were collected during two sea

206 This percentage varied by operation: PM 15%, PM SLNB 25%, LC 33%, LIH 15%, and IH 31%.

207 f 80% of patients undergoing each operation: PM 5, PM SLNB 10, LC 15, LIH 15, and IH 15.

208 that four visual areas bordering V1 (LM, P, PM and RL) display complementary representations, with o

209 tter determines total expression and percent PM expression.

210 al treatment called Problem Management Plus (PM+) that lay community workers can be taught to deliver

211 complex networks to identify major potential PM 2.5 contributors and PM 2.5 transport pathways of a n

212 First, major potential PM 2.5 pollution contributors are identified for each cl

213 es rise to subthalamic (STN), premammillary (PM) and posterior hypothalamic (PH) populations.

214 Dorsal premotor (PMd) and primary motor (M1) cortices play a central role

215 result of a differential ability to preserve PM integrity.

216 gen oxides (NOx), ammonia (NH3), and primary PM are estimated from the PM2.5-mortality responses to t

217 Mitigation of primary PM appears to be the most efficient way for increasing h

218 Our results suggest that proper PM lipid composition is important to stabilize the centr

219 e meteorology-driven variations are removed, PM concentrations in South Korea have declined continuou

220 We aim to reveal PM 2.5 mobility between cities in China.

221 Moreover, [S]-HDL and [S]-PM showed higher uptake by plaque macrophages in compari

222 Among the three formulations, [S]-PM displayed the highest efficacy in reducing macrophage

223 poprotein ([S]-HDL), polymeric micelles ([S]-PM), and liposomes ([S]-LIP), that are loaded with the H

224 In conclusion, our data demonstrate that [S]-PM is a promising targeted drug delivery system, which c

225 rophages in comparison to [S]-LIP, while [S]-PM demonstrated the highest uptake by Ly6C(high) monocyt

226 se survival compared with AYAs with the same PMs.

227 ge in firing rate: -8.0%), whereas silencing PM L5 feedback suppressed responses of high-SF-preferrin

228 Simulated PM concentrations show a strong negative correlation (i.

229 ciations with atmospheric pollutant species (PM, NOx, trace elements, PAHs); the pros and cons of bio

230 ), where half the decreases in fuel specific PM (-66%), BC (-65%), and PN (-19%) emissions are due to

231 throughout the study with location-specific PM levels.

232 r were randomized to undergo either standard PM ("no shave", n = 116) or have additional CSM taken ("

233 Moreover, steady-state PM phosphatidylinositol 4,5-bisphosphate (PI[4,5]P2) lev

234 apply higher-order network analysis to study PM 2.5 transport.

235 SUNb-PM not only increased cytotoxic T-cell infiltration and

236 the Stat3 and AKT signaling pathways by SUNb-PM may induce tumor cell apoptosis or decrease tumor imm

237 polymeric micelle nano-delivery system (SUNb-PM), working in a synergistic manner with vaccine therap

238 eports that interannual variation of surface PM concentration in South Korea is closely linked with t

239 The long-term trend of surface PM concentration in the SMA declined in the 2000s, but s

240 serum response factor) pathway for sustained PM blebbing and entotic invasion.

241 two complementary studies of: (i) long-term PM <2.5 mum (PM2.5) levels and osteoporosis-related frac

242 We found that PM PPIns depletion caused rapid translocation of K-Ras b

243 In addition, we report that PM with a negative surface charge can adsorb cationic AM

244 We found that PMd and PMv have strikingly different effects on M1 outp

245 One way that PMd and PMv could play distinct roles in hand movements

246 The PM quantity and size were mainly dependent on the region

247 irect lipid transport between the ER and the PM in the control of insulin secretion, a process impair

248 iscuss the cross talk between the ER and the PM mediated by direct contacts.

249 st, cells with reduced Cdc42 activity at the PM displayed altered centrosome morphology, suggesting t

250 ts depletion decreased Cdc42 activity at the PM.

251 ation may be mediated by active Cdc42 at the PM.

252 permits the cell to functionally connect the PM with the nucleus and represents to our knowledge the

253 ed PM polyphosphoinositides (PPIns) from the PM alters the intracellular distribution and activity of

254 s, delayed diacylglycerol clearance from the PM and impaired Ca(2+)-triggered phosphatidylserine scra

255 ranslocation of K-Ras but not H-Ras from the PM to the Golgi.

256 etrograde intracellular trafficking from the PM to the nucleus via the endosome-ER network.

257 PPIns depletion from the PM was achieved either by agonist-induced activation of

258 loss of pre-assembled Gag lattices from the PM.

259 We conclude that PPIns in the PM are important regulators of K-Ras-mediated signals.

260 activity, however, we found that ICMS in the PM can provide instructions to perform specific reach, g

261 The former determines NHE3 stability in the PM, and the latter determines total expression and perce

262 1.1, located approximately 12 nm away in the PM.

263 tion may involve insertion of STIM1 into the PM.

264 perform computer simulations of SVs near the PM at resting active zones, and the results show that th

265 a significant reduction in half-life of the PM pool of NHE3 in only the internal PBM mutation but no

266 On the basis of the PM-bound PAH concentrations and their activities reporte

267 roteins were reduced in the CR and/or on the PM.

268 oes at the cell surface and link them to the PM and clathrin coat.

269 morphogenesis beyond Gag recruitment to the PM and suggest a dynamic equilibrium of Gag-lipid intera

270 4B, but trafficking of nascent KRAS4B to the PM is incompletely understood.

271 with large, flat ER cisternae apposed to the PM, sometimes with a notably narrow lumen (thin ER).

272 tant for permanent K-Ras localization to the PM.

273 t) prevents its export from the Golgi to the PM.

274 inhibits cargo transport from the TGN to the PM.

275 eticulum inhibited delivery of KRAS4B to the PM.

276 linositol phosphatases were recruited to the PM.

277 n important role in their recruitment to the PM.

278 out the spatial relationship of SVs with the PM at active zones.

279 nd distribution of its contact area with the PM, thus priming and that the area correlates with the s

280 n their SV, directly linking the SV with the PM, varies by random shortening and lengthening of the m

281 ven be uncorrelated, as was observed for the PMd/M1 population as a whole.

282 The PMs showed both striking similarities, despite significa

283 Of these 421 women, 209 were assigned to PM+ and 212 to EUC.

284 n: 0.04 cycles per degree [cpd]) compared to PM L5 feedback neurons (0.15 cpd).

285 n milk fat of cows grazing a CSP compared to PM.

286 randomly allocated in a 1:1 ratio either to PM+ delivered in the community by lay community health w

287 We aimed to examine whether exposure to PM air pollution is related to risk of Parkinson's disea

288 Exposure to PM and NO2 air pollution was associated with the prevale

289 significant associations between exposure to PM and PD risk.

290 cholesterol travels from lysosomes first to PM to meet cholesterol needs, and subsequently from PM t

291 The germplasm with immunity to PM are good sources of resistance for PM resistance bree

292 To characterize genetic susceptibility to PM-associated QT prolongation in a multi-racial/ethnic,

293 nd biopsies (n = 47) (Affymetrix HT HG-U133+ PM).

294 and November 25, 2013, 235 women undergoing PM for Stage 0-III breast cancer were randomized to unde

295 further exploring the mechanisms underlying PM phosphoinositide regulation.

296 gnetic content, may successfully allow urban PM source apportionment.

297 n marker-assisted selection to improve wheat PM resistance after further validation.

298 Whether PM is associated with loss of bone mineral density (BMD)

299 regulation correlates with SCNA but not with PM burden, yielding downstream effectors of TP53 and MYC

300 d MMc in offspring of women with and without PM.