ライフサイエンスコーパス: PRL receptor

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1 HOD6 cells, which constitutively express the PRL receptor.

2 referentially binds to the short form of the PRL receptor.

3 determined that PLP-J does not interact with PRL receptors.

4 r biological effects by interacting with the PRL receptor, a Janus kinase (JAK)2-coupled cytokine rec

5 These results demonstrate that PRL receptor activation promotes the acute activation of

6 We therefore assessed whether prolactin (PRL) receptor activation promotes activation of PKC delt

7 These results indicate that Prl receptors, after binding the ligand, activate severa

8 PRL receptor agonists induced translocation PKC delta fr

9 Using these assays, we assessed whether PRL receptor agonists were capable of activating PKC del

10 expressing EC induces phosphorylation of the PRL receptor and activates MAPK.

11 t this protein is immunoprecipitated by anti-PRL receptor and anti-phosphotyrosine antibodies.

12 ons, one of which is a paucity of functional PRL receptors, and that murine Stat5 overexpression is a

13 hether interruption of this growth loop by a PRL receptor antagonist, an S179D mutant PRL, could inhi

14 e inhibition of growth in vitro by the S179D PRL receptor antagonist.

15 a rat ovarian-specific phosphoprotein, PRAP (PRL Receptor Associated Protein), which has no significa

16 Using PRL receptor-deficient (Prlr(-/-)) and PRL-deficient (Pr

17 d genes, we now report that costimulation of PRL receptors did not interfere with IFN alpha/beta sign

18 The short form of the PRL receptor failed to transactivate ntcp GLEs.

19 ith either the long or the short form of the PRL receptor, fusion proteins with glutathione S-transfe

20 Both the long and short form of the PRL receptor have been identified in the corpus luteum o

21 We show dramatically increased expression of PRL receptor in ovarian and endometrial tumors as well a

22 Because the PRL receptor is not directly involved in cAMP metabolism

23 Thus, the long form and short forms of the PRL receptor may signal through distinct pathways.

24 poptotic effect of cytokines was enhanced in PRL receptor-null (Prlr(-/-)) mice.

25 ifying DAergic neuron populations expressing PRL receptor (PRL-R); (2) to describe the effect of ovar

26 novel fusion protein was able to bind to the PRL receptor (PRLR) on T-47D human breast cancer cells a

27 However, the mechanisms of PRL receptor (PRLr) proteolysis remain largely to be det

28 eport that in prolactin (PRL)-treated cells, PRL receptor (PRLR) undergoes cytoplasmic loop dimerizat

29 Although Prl receptor (PrlR)-null mice are infertile, we were abl

30 logous expression system and TG neurons from PRL receptor (PRLR)-null mutant mice by expressing rat P

31 Naturally occurring DeltaS2 PRL receptors (PRLR) were also found in normal and cance

32 The intracellular domain of the prolactin (PRL) receptor (PRLr) is required for PRL-induced signali

33 equired coexpression of the long form of the PRL receptor (PRLRL) and Stat5.

34 stimulates hypothalamic dopamine neurons via PRL receptors (PRLRs) in a short-loop feedback circuit.

35 Both forms of PRL receptors (PRLRs), short and long, were also present

36 the PRL family (e.g., PLP-A does not use the PRL receptor) produced by trophoblast cells of the chori

37 In PRL receptor reconstituted COS cells cotransfected with

38 ogenic actions through the GH and prolactin (PRL) receptors, respectively.

39 During PRL receptor signaling, Vav2 becomes phosphorylated and

40 ment with S179D PRL, expression of the short PRL receptor was doubled, and signaling showed a greater

41 smic domain of the long or short form of the PRL receptor were produced, purified, and incubated with

42 of transcription 5a (STAT5a) and prolactin (PRL) receptor, which is essential for PRL-provoked STAT5

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