ライフサイエンスコーパス: PVN

1 PVN AT1a deletion did not affect body mass or adiposity

2 PVN cells project also to laminae I and outer II of the

3 PVN inhibition did not affect the amplitude of the inspi

4 PVN injections of the neuropeptide pituitary adenylate c

5 PVN neurons labeled with retrograde tracer from rVLM wer

6 rostral (71 +/- 3%) than caudal (33 +/- 8%) PVN.

7 ely maintained in anaesthetized DH rats by a PVN-driven component of sSNA that is neither respiratory

8 While the location of a PVN-homologous region has been described in adult fish a

9 elevated blood pressure responses through a PVN opioid mechanism.

10 a circuit whereby brainstem GLP-1 activates PVN signaling to mount an appropriate whole-organism res

11 as a negative feedback signal that activates PVN neurons to alleviate weight gain.

12 bilaterally vagotomized and underwent acute PVN inhibition by bilateral injection of the GABA-A rece

13 Despite this increased adiposity, PVN AT1a deletion reduced systolic blood pressure, sugge

14 h metabolic and cardiovascular disorders and PVN AT1a deletion reduced indices of hypothalamic inflam

15 verity of PV replication, tissue injury, and PVN disease grades.

16 rved in the ARC but absent from the rPOA and PVN.

17 in numerous regions, including the rPOA and PVN.

18 al cells, but only at a low level in SON and PVN neurons, whereas robust upregulation in AVP neurons

19 s levels in the cortex, dorsal striatum, and PVN were significantly greater in Pitx3-/- than +/+ mice

20 und that ArcN NPY/AgRP fibers closely appose PVN and DMH presympathetic neurons.

21 ncluding calcium-permeable AMPA receptors at PVN postsynaptic sites.

22 ked activity of cardiovascular barosensitive PVN neurons that also project directly to the rVLM.

23 analysis to examine the relationship between PVN NMDA receptors and the blood pressure increase induc

24 NR1 subunit trafficking in ERbeta-containing PVN neurons.

25 hologic classification scheme for definitive PVN from the Banff Working Group on Polyomavirus Nephrop

26 ted morphologic classification of definitive PVN that groups histologic changes, reflects clinical pr

27 he largest systematic analysis of definitive PVN undertaken thus far.

28 from patients with biopsy-proven definitive PVN.

29 , noninvasive urinary PV-Haufen test detects PVN in kidney transplant recipients with greater than 95

30 aufen numbers strongly correlated with early PVN grade 1 and minimal intrarenal expression of SV40-T

31 emales, NR1 density is upregulated in ERbeta-PVN dendrites and ultimately leads to the neurohumoral d

32 ale mice, NR1 density is decreased in ERbeta-PVN dendrites thus reducing NMDA receptor activity and p

33 atomical and functional extent of this M/T-->PVN-->M/T circuit contrasts with the narrowly confined M

34 However, the true burden of post-HCT PVN is unknown because kidney biopsies are avoided due t

35 V-Haufen was correlated with both histologic PVN disease grades 1 to 3 and the number of SV40-T-expre

36 lation activates neurons in the hypothalamic PVN.

37 paraventricular nucleus of the hypothalamus (PVN) and median preoptic nucleus (MnPO), but not in the

38 paraventricular nucleus of the hypothalamus (PVN) by alpha-MSH and AgRP can be mediated independently

39 paraventricular nucleus of the hypothalamus (PVN) dose-dependently suppressed lumbar SNA (LSNA) and i

40 paraventricular nucleus of the hypothalamus (PVN) of mice.

41 paraventricular nucleus of the hypothalamus (PVN) send descending projections to the superior salivat

42 paraventricular nuclei of the hypothalamus (PVN) to the CA2 as well as a projection from pyramidal n

43 paraventricular nucleus of the hypothalamus (PVN), and SB334867 was locally administered intra-PVN (1

44 paraventricular nucleus of the hypothalamus (PVN), in both Pitx3+/+ and -/- mice.

45 paraventricular nucleus of the hypothalamus (PVN), to block alpha-melanocyte-stimulating hormone (alp

46 paraventricular nucleus of the hypothalamus (PVN), which is involved in the regulation of food intake

47 paraventricular nucleus of the hypothalamus (PVN).

48 paraventricular nucleus of the hypothalamus (PVN).

49 paraventricular nucleus of the hypothalamus (PVN).

50 n reduced anxiety-like behavior, implicating PVN GLP-1 signaling in behavioral stress reactivity.

51 /adapter NOX p47(phox) subunit is altered in PVN dendrites following AngII administered (14 days) dur

52 ude of NMDAR-EPSCs and puff NMDA currents in PVN neurons in WKY rats but not in SHRs.

53 trated by the finding that GluN1 deletion in PVN neurons attenuated the Ang II-induced increases in b

54 m deficiency) or increase (sodium excess) in PVN Galphai(2) proteins; plasma norepinephrine levels we

55 ntified prominent NPS receptor expression in PVN-OXT neurons.

56 NK3Rs have been localized in PVN neurons and have showed nuclear translocation follow

57 In the present study, densities of NK3Rs in PVN AVP- or OC-labeled somatodendritic profiles were mea

58 ) and a decrease in cytoplasmic p47(phox) in PVN AVP dendrites.

59 ts indicate that NMDA receptor plasticity in PVN neurons significantly contributes to the elevated bl

60 ogen receptors beta (ERbetas) are present in PVN neurons.

61 ion augments excitatory synaptic strength in PVN corticotropin-releasing hormone (CRH) neurons, with

62 ating that endogenous NPY tonically inhibits PVN presympathetic neurons.

63 s from index biopsies at the time of initial PVN diagnosis.

64 r an NPY receptor Y1 (NPY1R) antagonist into PVN or DMH decreased or increased SSNA, respectively.

65 njections of the GABAA agonist muscimol into PVN inhibit both basal and meningeal-evoked activities o

66 and SB334867 was locally administered intra-PVN (10 nmol/side) to test the specific involvement of H

67 tic effect of NPS seen after i.c.v. or intra-PVN infusion requires responsive OXT neurons of the PVN

68 ograde tracing experiments showed that intra-PVN or intra-BNST red fluorobead unilateral injection la

69 NPY1 and opioid receptors in the ipsilateral PVN converted the decreases in MAP and SNA to increases

70 tin 3/4 (MC3/4) receptors in the ipsilateral PVN.

71 MDAR-EPSCs and puff NMDA currents in labeled PVN neurons in SHRs but had no effect in WKY rats.

72 However, AMPAR-EPSCs of labeled PVN neurons in spontaneously hypertensive rats (SHR) dis

73 d puff NMDA currents in retrogradely labeled PVN neurons were significantly higher in SHRs than in WK

74 llular cells interspersed with magnocellular PVN neurons expressing secretagogin.

75 brafish neuropeptides found in the mammalian PVN (CCK, CRH, ENK, NTS, SS, VIP, OXT, AVP), we provide

76 O and the homologous region to the mammalian PVN.

77 on with ERbeta-ir (48 +/- 16%) in the middle PVN.

78 Moderate PVN occurred in 30% of the PVs, in 78% of the patients;

79 Moderate PVN was defined as a pulmonary vein diameter reduction o

80 Moreover, PVN injection of Y1 and Y5 receptor antagonists in other

81 We recommend using this morphologic PVN classification scheme for diagnostic communication,

82 d striking differences between rat and mouse PVN cytochemistry, but careful exploration of PVN ERbeta

83 l differences in ERbeta neurons of the mouse PVN that are different from that previously described fo

84 polymer electret (poly(2-vinyl naphthalene) (PVN)) and metal nanoparticles (Copper).

85 The risk of pulmonary vein narrowing (PVN) after pulmonary vein isolation, using a novel multi

86 Polyomavirus nephropathy (PVN) is a common viral infection of renal allografts, wi

87 e urinary test for polyomavirus nephropathy (PVN) is the PV-Haufen test.

88 itis and also with polyomavirus nephropathy (PVN).

89 We examined neuroendocrine, PVN CRH neurons and report that social isolation alters

90 otp, arx, dlx5a, isl1) in and around the NPO/PVN together with neuropeptide expression within it.

91 In the paraventricular nuclei (PVN) of the hypothalamus, DOC pretreatment diminished bo

92 in the hypothalamic paraventricular nucleus (PVN) and arcuate nucleus (ARC).

93 projections to the paraventricular nucleus (PVN) and dorsomedial hypothalamus (DMH).

94 of the hypothalamic paraventricular nucleus (PVN) and released into the portal circulation at the med

95 regions such as the paraventricular nucleus (PVN) and rostral preoptic area (rPOA).

96 sacrificed, and the paraventricular nucleus (PVN) and rostral ventrolateral medulla (RVLM) were micro

97 brain regions, the paraventricular nucleus (PVN) and the bed nucleus of stria terminalis, revealed g

98 in the hypothalamic paraventricular nucleus (PVN) are mediated via actions on local OXT neurons in ma

99 in the hypothalamic paraventricular nucleus (PVN) in a nutritional state-dependent manner by activati

100 The paraventricular nucleus (PVN) in mammals is the main hypothalamic nucleus control

101 n, the hypothalamic paraventricular nucleus (PVN) is activated and drives SNA in support of arterial

102 The hypothalamic paraventricular nucleus (PVN) is critically involved in elevated sympathetic outp

103 pression within the paraventricular nucleus (PVN) is critically linked to the increased sympathoexcit

104 in the hypothalamic paraventricular nucleus (PVN) is crucial for the sympathoexcitation driving AngII

105 in the hypothalamic paraventricular nucleus (PVN) is increased and critically involved in heightened

106 essing hypothalamic paraventricular nucleus (PVN) neurons in "menopausal" female mice.

107 The paraventricular nucleus (PVN) of the hypothalamus controls the autonomic neural o

108 R) activity, in the paraventricular nucleus (PVN) of the hypothalamus is closely associated with high

109 AR) activity in the paraventricular nucleus (PVN) of the hypothalamus is involved in elevated sympath

110 omic neurons in the paraventricular nucleus (PVN) of the hypothalamus play a large role in the regula

111 ia derived from the paraventricular nucleus (PVN) of the hypothalamus, where loss of OGT was associat

112 y of neurons in the paraventricular nucleus (PVN) of the hypothalamus.

113 ly expressed in the paraventricular nucleus (PVN) of the hypothalamus.

114 mone (CRH) from the paraventricular nucleus (PVN) of the hypothalamus.

115 in the hypothalamic paraventricular nucleus (PVN) or in the ventromedial nucleus (VMH), restored plas

116 to the hypothalamic paraventricular nucleus (PVN) or into the bed nucleus of the stria terminalis (BN

117 ctions, activity in paraventricular nucleus (PVN) OXT neurons increased.

118 in the hypothalamic paraventricular nucleus (PVN) plays a critical role in regulating sympathetic out

119 om the hypothalamic paraventricular nucleus (PVN) plays a major role in the development of hypertensi

120 The paraventricular nucleus (PVN) regulates sympathetic outflow and blood pressure.

121 murine hypothalamic paraventricular nucleus (PVN) was altered by changes in nutritional state.

122 At the end, the paraventricular nucleus (PVN) was analyzed by Real-time RT-PCR and Western blot.

123 ptic nucleus (SON), paraventricular nucleus (PVN), dorsomedial nucleus (DM), ventromedial nucleus (VM

124 enous, hypothalamic paraventricular nucleus (PVN)-specific, decrease (sodium deficiency) or increase

125 of the hypothalamic paraventricular nucleus (PVN).

126 mone neurons in the paraventricular nucleus (PVN).

127 of the hypothalamic paraventricular nucleus (PVN).

128 gh the hypothalamic paraventricular nucleus (PVN).

129 ateral hypothalamic paraventricular nucleus (PVN).

130 ZI, 15%), CeA (5%), paraventricular nucleus (PVN, 13%), SLEA (66%), and MPA (26%).

131 The activation of PVN neurons in both fasted Nckx4 knock-out and glucose-i

132 luR1 had no effect on the firing activity of PVN neurons in either group.

133 AMPAR-EPSC amplitude and firing activity of PVN neurons in SHR than in WKY rats.

134 f miniature EPSCs and the firing activity of PVN neurons in SHRs.

135 ) similarly increased the firing activity of PVN neurons in WKY rats and SHRs.

136 at increased GluR2-lacking AMPAR activity of PVN neurons results from GluR2 internalization through N

137 le of CaMKII in regulating NMDAR activity of PVN presympathetic neurons in male spontaneously hyperte

138 duced the spontaneous and evoked activity of PVN.

139 GFP) to examine the chemical architecture of PVN ERbeta cells.

140 The sympathoexcitation following blockade of PVN NPY inhibition was eliminated by prior PVN nanoinjec

141 rtant basis for cross-species comparisons of PVN/NPO structure and function.

142 ine samples, with histologic confirmation of PVN in 1 autopsy specimen.

143 , we sought to determine the contribution of PVN to support of rhythmic bursting of SNA during dehydr

144 DAR-EPSCs and puff NMDA-elicited currents of PVN neurons in SHRs than in WKY rats.

145 DHPG-induced increases in NMDAR currents of PVN neurons in SHRs.

146 ion in plasma membrane GluN1 in dendrites of PVN neurons in adult male mice.

147 we demonstrate that the synaptic dynamics of PVN recruitment in mouse visual cortex are customized ac

148 ished inward rectification of AMPAR-EPSCs of PVN neurons in SHR.

149 GluN2A to NMDAR-EPSCs and miniature EPSCs of PVN neurons in SHRs.

150 equency of NMDAR-mediated miniature EPSCs of PVN neurons in SHRs.

151 AR-dependent increase in the excitability of PVN neurons only in WKY rats.

152 ARs contributes to increased excitability of PVN presympathetic neurons and sympathetic vasomotor ton

153 aptic NMDAR activity and the excitability of PVN presympathetic neurons in hypertension.

154 VN cytochemistry, but careful exploration of PVN ERbeta neurons in mice has been hindered by a lack o

155 hat the GABA reversal potential (E(GABA)) of PVN presympathetic neurons undergoes a depolarizing shif

156 and their relevance to the hyperactivity of PVN presympathetic neurons in hypertension remain unclea

157 sion and contributes to the hyperactivity of PVN presympathetic neurons through PKC- and SNAP-25-medi

158 izes E(GABA) and restores GABA inhibition of PVN neurons in SHRs.

159 Conversely, inhibition of PVN OXT axon terminals in the VTA decreased social inter

160 restores E(GABA) and GABAergic inhibition of PVN presympathetic neurons in SHRs.

161 nagement for the diagnosis and prediction of PVN disease grades and monitoring of disease course duri

162 N AT1a deletion eliminates responsiveness of PVN parvocellular neurons to Ang-II, and suggest that An

163 The selective shift of PVN frequency tuning should render pup odor-induced disi

164 This enhanced local recruitment depends on PVN-mediated reciprocal inhibition and results from both

165 physical stress has sex-specific effects on PVN CRH neurons.

166 Confirming this assumption, intra-BNST or PVN Hcrt-1/Ox-A injection enhanced alcohol seeking simil

167 borated by the hypothalamic paraventricular (PVN) and supraoptic (SON) nuclei.

168 in the hypothalamus (i.e., paraventricular [PVN], supraoptic [SON], and suprachiasmatic [SCN]) and e

169 Parvocellular PVN neurons project to sympathoexcitatory cardiovascular

170 a-EGFP neurons predominated in the posterior PVN.

171 V-Haufen shed per milliliter urine, predicts PVN disease grades and the severity of intrarenal PV rep

172 f PVN NPY inhibition was eliminated by prior PVN nanoinjection of the melanocortin 3/4 receptor inhib

173 of retrogradely labeled spinally projecting PVN neurons displayed a larger amplitude and shorter dec

174 of retrogradely labeled spinally projecting PVN neurons exhibited a linear current-voltage relations

175 urrents were recorded in spinally projecting PVN neurons in SHRs and male Wistar-Kyoto (WKY) rats.

176 urrents were recorded in spinally projecting PVN neurons in spontaneously hypertensive rats (SHRs) an

177 basal firing activity of spinally projecting PVN neurons in spontaneously hypertensive rats (SHRs), b

178 PG-induced excitation of spinally projecting PVN neurons.

179 inputs may facilitate rapid and proportional PVN recruitment in regulating local circuit operations.

180 esults of this study suggest that in the rat PVN 1) NK3R distribution is conducive to modulation of s

181 ings demonstrate plasticity of liver-related PVN neurons and a shift toward excitation in a diabetic

182 s were silent, indicating that liver-related PVN neurons are more active in db/db mice.

183 ms controlling the activity of liver-related PVN neurons are not known.

184 TRPV1-dependent excitation of liver-related PVN neurons diminishes in type 1 diabetes, thus indicati

185 In db/db mice, the majority of liver-related PVN neurons fired spontaneously; whereas, in lean mice t

186 tional role of TRPV1 regarding liver-related PVN neurons has to be elucidated.

187 urotransmission was reduced in liver-related PVN neurons of db/db mice.

188 Liver-related PVN neurons were identified with a retrograde, trans-syn

189 , in lean mice the majority of liver-related PVN neurons were silent, indicating that liver-related P

190 otal role in the regulation of liver-related PVN neurons.

191 indicate that TRPV1 regulates liver-related PVN neurons.

192 vidence of overall activity of liver-related PVN neurons.

193 inate from altered activity of liver-related PVN neurons.

194 c inhibition was identified in liver-related PVN neurons; although, the magnitude of tonic inhibitory

195 meostasis and colocalizes with liver-related PVN neurons; however, the functional role of TRPV1 regar

196 ha-MSH) inhibit and stimulate, respectively, PVN-RVLM neurons.

197 tion of fluorogold revealed that the rostral PVN ERbeta-EGFP cells are neuroendocrine neurons whereas

198 Severe PVN in 15% of patients raises concerns about the risk fo

199 diameter reduction of 25 to 50%, and severe PVN as >50%.

200 % of the PVs, in 78% of the patients; severe PVN occurred in 4% of the PVs, in 15% of the patients.

201 e-cell patch-clamp recordings confirmed that PVN AT1a deletion eliminates responsiveness of PVN parvo

202 Collectively, these studies demonstrate that PVN AT1a regulate energy balance during environmental ch

203 Collectively, these data demonstrate that PVN Galphai(2) protein pathways play an endogenous role

204 Given that PVN neurones project to brainstem cardio-respiratory reg

205 irst evidence supporting the hypothesis that PVN Sirt1 activates the hypothalamic-pituitary-adrenal a

206 Gene expression studies revealed that PVN AT1a deletion decreased hypothalamic expression of c

207 Here, we show that PVN-specific loss of G(q)alpha and G11alpha, which stimu

208 Collectively, these data suggest that PVN NPY inputs converge with alpha-MSH to influence pres

209 The PVN also harbors parvocellular OT cells that project to

210 The PVN classes 1-3 as described here can easily be recogniz

211 ly involved in stress regulation such as the PVN and the BNST.

212 E2 administration in both the PVN and the VMH resulted in peripheral insulin resistanc

213 volume in any area in either sex except the PVN of male monkeys, which showed a significant increase

214 Innervation from the PVN and SON is found in brain regions that likely work i

215 Novel connections from the PVN and to the SUM suggest important regulatory roles fo

216 diated sympathoexcitatory responses from the PVN in CHF.

217 Isolated non-VP-eGFP neurons from the PVN of AngII-infused mice also showed an increase in bas

218 n signal, possibly relayed directly from the PVN to the OVLT.

219 est that CaMKII activity is increased in the PVN and contributes to potentiated presynaptic and posts

220 tion of ArcN NPY/AgRP terminal fields in the PVN and DMH decreased SSNA.

221 revealed labeling of neurons located in the PVN and dorsomedial hypothalamic nucleus.

222 The mRNA and protein levels of mGluR5 in the PVN and rostral ventrolateral medulla were significantly

223 ut not ETB receptors were upregulated in the PVN and RVLM of E2 treated animals.

224 rotein levels of NKCC1, but not KCC2, in the PVN are significantly increased in SHRs, and the NKCC1 p

225 neural substrates of oxidative stress in the PVN associated with AngII hypertension in postmenopausal

226 is lost in mice lacking G(q/11)alpha in the PVN but not in animals deficient for G(s)alpha.

227 1 tonically suppresses NMDAR activity in the PVN by reducing the NMDAR phosphorylation level.

228 ition, the increased c-Fos expression in the PVN during withdrawal was dependent on hypocretin transm

229 interaction whereby mice lacking AT1a in the PVN had increased food intake and decreased energy expen

230 female PNS offspring in the NTS, and in the PVN in males.

231 ponses to GABA(A) receptor activation in the PVN in SHRs.

232 Our results show that Sirt1 levels in the PVN increase in rats fed a high fat diet for 12 weeks.

233 ow that postnatal depletion of GLP-1R in the PVN increases food intake and causes obesity.

234 Our findings suggest that mGluR5 in the PVN is upregulated in hypertension and contributes to th

235 s of ETA receptor were also increased in the PVN of E2 treated animals.

236 exercise-induced improvement in PICs in the PVN of hypertensive rats; however, the improvements in I

237 y responses to microinjection of NMDA in the PVN of rats with CHF.

238 Selective overexpression of Tmem18 in the PVN of wild-type mice reduced food intake and also incre

239 Direct activation of these neurons in the PVN or their terminals in the VTA enhanced prosocial beh

240 ypocretin signaling acting on Hcrtr-1 in the PVN plays a crucial role in the expression of nicotine w

241 stasis and impair synaptic inhibition in the PVN to augment the sympathetic drive in hypertension.

242 Also, the CK1epsilon protein level in the PVN was significantly lower in SHRs than in WKY rats.

243 l protein levels of GluN2A and GluN2B in the PVN were greater in SHRs than in WKY rats.

244 In addition, when action potentials in the PVN were inhibited with intraparenchymal lidocaine, AngI

245 the synaptosomal GluN2A protein level in the PVN were significantly higher in SHRs than in WKY rats.

246 via GABA-A, NPY1 and opioid receptors in the PVN, 2) lowering of BLMAP converted decreases in MAP fol

247 y, MC4R-dependent oxytocin expression in the PVN, a key essential step in satiety, is prevented by bl

248 n level of GluN2B serine 1303 (S1303) in the PVN, but not in the hippocampus and frontal cortex, was

249 mpanied by hyperactivation of neurons in the PVN, evidenced by high levels of c-Fos expression.

250 E2 administration in the VMH, but not in the PVN, increased EGP and induced hepatic insulin resistanc

251 be regulated primarily though action in the PVN, is unknown.

252 neurons inhibit anorexigenic neurons in the PVN, revealing a basic orexigenic nature of these cells.

253 -1 (CK1) in regulating NMDAR activity in the PVN.

254 via an increase in alpha-MSH activity in the PVN.

255 tion of oxytocin, a peptide expressed in the PVN.

256 on of glucocorticoid-responsive genes in the PVN.

257 -10), and attenuated oxidative stress in the PVN.

258 ion were mediated via MC3/4 receptors in the PVN.

259 level of phosphorylated GluN2B S1303 in the PVN.

260 estored with opioid receptor blockade in the PVN.

261 nimals lacking G(s)alpha specifically in the PVN.

262 Hypocretin neurons directly innervate the PVN and the local infusion of SB334867 into the PVN decr

263 In addition, microinjection of NAS into the PVN decreased blood pressure and lumbar sympathetic nerv

264 and the local infusion of SB334867 into the PVN decreased the expression of nicotine withdrawal.

265 GABAA antagonist gabazine infusions into the PVN facilitate meningeal-evoked responses of Sp5C neuron

266 ntagonist via reverse microdialysis into the PVN or VMH attenuated the effect of systemic E2 on plasm

267 In addition, microinjection of AIP into the PVN significantly reduced arterial blood pressure and lu

268 roinjection of the NMDAR antagonist into the PVN.

269 usion requires responsive OXT neurons of the PVN and locally released OXT.

270 lar distribution in AVP or OC neurons of the PVN and plasticity following restraint stress in rats ar

271 -GlcNAcylation in alphaCaMKII neurons of the PVN as an important molecular mechanism that regulates f

272 Ultrastructural analysis of the PVN demonstrated p47(phox) immunolabeling in many glial

273 ify the definitive borders and extent of the PVN homologous region in larval zebrafish and serve as a

274 All NK3-labeled somata of the PVN in control rats showed cytoplasmic but no nuclear im

275 Inhibition of the PVN with naloxone reversed the EA-inhibition.

276 tered autonomic circuits at the level of the PVN, which can contribute to autonomic dysfunction and d

277 er sparsely distributed in OC neurons of the PVN.

278 dexamethasone for 90 min into the ARC or the PVN did not have significant effects on basal plasma glu

279 or agonist dexamethasone into the ARC or the PVN, in combination with isotope dilution and hyperinsul

280 We hypothesized that the PVN and its projections to the rVLM participate in the E

281 neuronal tracers was examined throughout the PVN.

282 Thus, the PVN and its projection to rVLM are important in processi

283 ropose that the ArcN NPY neuropathway to the PVN and DMH is pivotal in obesity-induced elevations in

284 s NPY neurons projecting from the ARC to the PVN are pivotal for balancing feeding behavior and gluco

285 agonist naratriptan infusion confined to the PVN depresses both basal and meningeal-evoked Sp5C activ

286 ARCN neurons projecting to the PVN were immunoreactive for glutamic acid decarboxylase

287 nstem locus coeruleus, and projecting to the PVN.

288 bservations, HIF-1alpha silencing within the PVN abrogated the increased basal sympathetic tone and s

289 nt somatodendritic release of OXT within the PVN as assessed by microdialysis in combination with a h

290 mulation of GLP-1 afferent fibers within the PVN is sufficient to suppress food intake independent of

291 We conclude that subtle hypoxia within the PVN may act as a metabolic cue to modulate sympathoexcit

292 le factor 1alpha were upregulated within the PVN of left coronary artery-ligated CHF rats.

293 ogenetic silencing of OXT neurons within the PVN prevented the effect of synthetic NPS.

294 potent inhibitory neuromodulator within the PVN that may contribute to changes in SNA that occur in

295 regulation of energy homeostasis within the PVN.

296 d non-vasopressin neurons located within the PVN.

297 formed the basis for the definition of three PVN classes that correlated strongest with three clinica

298 systemic and/or central AVP release through PVN inputs to the posterior pituitary and/or the amygdal

299 the ability of an MC4R agonist delivered to PVN to inhibit food intake is lost in mice lacking G(q/1

300 potentiated glutamatergic synaptic input to PVN presympathetic neurons and elevated sympathetic vaso

301 e detection of PV-Haufen suggests underlying PVN with an increased risk of kidney failure and dialysi