ライフサイエンスコーパス: PWV

1 PWV and AGI decreased to a nadir at 6 weeks [PWV to 74.2

2 PWV and AI are deeply modified in SCD patients in compar

3 PWV was determined between the mid-ascending and -descen

4 PWV was higher (i.e., increased aortic stiffness) in HCM

5 PWV was not associated with the child's current oily fis

6 PWV was significantly associated with adulthood systolic

7 PWV was significantly higher in HCM patients compared wi

8 l (P = 0.30), C-reactive protein (P = 0.10), PWV (P = 0.30), or AI (P = 0.84).

9 s (<30 ng/mL) for changes in FMD (p = 0.65), PWV (p = 0.93), AIx (p = 0.97), or CRP (p = 0.26).

10 n FMD (0.3 [3.4] vs. 0.3 [2.6] %, p = 0.77), PWV (0.00 [1.06] vs. 0.05 [0.92] m/s, p = 0.65), AIx (2.

11 al to the common iliac artery did not affect PWV.

12 iliac artery (via the sheath) did not affect PWV.

13 After PWV was added to a standard risk factor model, integrate

14 though aortic PWV rose similarly with aging, PWV had more of an influence on PP in women than did mea

15 here were no significant differences in AIx, PWV, or BP between treatments over time.

16 In subjects with active disease, the AIx, PWV, and level of CRP were elevated compared with that i

17 mpared with quintile 1; P-trend = 0.04), and PWV (-0.4 +/- 0.2 m/s for quintile 5 compared with quint

18 ard, whereas the Einc versus TP (P<0.05) and PWV versus TP (P<0.01) curves were shifted downward.

19 No association was noted between HDL-C and PWV.

20 (E') varied inversely with Zc, SVRI, Ea, and PWV (r = -0.4 to 0.5; beta = 1.0 to 1.2; p < or = 0.004)

21 V and mortality showed a ceiling effect, and PWV was truncated at 12 m/sec.

22 c compliance and decreases isobaric Einc and PWV in the human brachial artery.

23 We measured blood pressure and PWV photoplethysmographically at a median corrected post

24 in diastolic BP, mean arterial pressure, and PWV (-2.24 +/- 1.31 mm Hg, -1.24 +/- 1.30 mm Hg, and -0.

25 Brachial-ankle PWV was significantly higher among Abeta-positive partic

26 emoral-ankle PWV), and mixed (brachial-ankle PWV) vascular beds.

27 Femoral-ankle PWV was only higher among Abeta-positive participants at

28 eart-femoral PWV), peripheral (femoral-ankle PWV), and mixed (brachial-ankle PWV) vascular beds.

29 s with lower, below median GFR had higher Ao-PWV than those with GFR above the median (P = 0.043).

30 ent, raised ACR is associated with higher Ao-PWV, a relationship most likely mediated by raised BP.

31 with raised ACR (>/=3 mg/mmol) had higher Ao-PWV, poorer diabetic control, and higher pulse pressure

32 n analysis, the significant predictors of Ao-PWV were age, SBP or PP, duration of diabetes, gender, n

33 The closest univariate associations of Ao-PWV were positively with age, duration of diabetes, SBP,

34 The association of Ao-PWV with reduced GFR suggests that even modest renal dys

35 ACR emerged as a significant predictor of Ao-PWV.

36 together explained 55% of the variance of Ao-PWV.

37 Aortic pulse wave velocity (Ao-PWV) and albumin creatinine ratio (ACR) were measured in

38 omen's Survey), the child's descending aorta PWV was measured at the age of 9 years using velocity-en

39 Aortic PWV improves risk prediction when added to standard risk

40 Aortic PWV is a powerful independent predictor of mortality in

41 1.01 and -0.67 +/- 0.91; p = 0.002), aortic PWV (-0.69 +/- 1.15 m/s and -0.71 +/- 0.71 m/s; p = 0.00

42 scular mortality associated with age, aortic PWV, and aortic bifurcation diameter with high specifici

43 Although aortic PWV rose similarly with aging, PWV had more of an influe

44 r, the age-related changes in AIx and aortic PWV were non-linear, with AIx increasing more in younger

45 g and risk in younger individuals but aortic PWV is likely to be a better measure in older individual

46 y was associated with lower childhood aortic PWV (sex-adjusted beta=-0.084 m/s per portion per week;

47 l blood pressures and Doppler-derived aortic PWV were measured.

48 isplacing SBP as a prognostic factor, aortic PWV is probably further along the causal pathway for art

49 bPP; and 0.867, 0.851, and 0.825 for aortic PWV, aoPP, and Pb, respectively.

50 presence of diabetes mellitus, higher aortic PWV was associated with a 48% increase in cardiovascular

51 ted with the corresponding changes in aortic PWV (r = 0.53 to 0.61, p < 0.01).

52 iated with a concomitant reduction in aortic PWV and improvement in endothelial function.

53 The age-associated increase in aortic PWV was higher in patients (P<0.001).

54 locity (PWV) was measured invasively (aortic PWV).

55 was associated with an increased mean aortic PWV of 0.19 m/sec (95% CI: 0.03, 0.36) in total and an i

56 0.36) in total and an increased mean aortic PWV of 0.42 m/sec (95% CI: 0.03, 0.81) in the abdominal

57 the stiffness gradient [(brachial PWV/aortic PWV)(0.5)] and ascending aortic and aortic bifurcation d

58 eride content with total and regional aortic PWV and carotid IMT while adjusting for several possible

59 vel of systolic blood pressure (SBP), aortic PWV was greater in subjects with diabetes than in contro

60 Results Total aortic PWV (mean difference, 0.5 m/sec; 95% confidence interval

61 We tested whether aortic PWV predicts cardiovascular and all-cause mortality in t

62 estimated that a 1% increase in aortic arch PWV (in meters per second) is related to a 0.3% increase

63 aortic distensibility, increased aortic arch PWV (p < 0.001), and increased central blood pressures (

64 Aortic arch PWV helped predict WMH volume independent of the other d

65 Aortic arch PWV measured with phase-contrast MR imaging is a highly

66 model of subsequent WMH burden, aortic arch PWV provides a distinct contribution along with systolic

67 Aortic arch PWV was measured with phase-contrast magnetic resonance

68 ar regression was conducted with aortic arch PWV, 15 other cardiovascular risk factors, and age, sex,

69 d for sex and ethnicity included aortic arch PWV, age, systolic blood pressure, hypertension treatmen

70 1 production directly regulates large artery PWV in vivo.

71 The association between PWV and mortality showed a ceiling effect, and PWV was t

72 The association between PWV and mortality was assessed in a Cox regression analy

73 RP level was positively correlated with both PWV and the AIx.

74 e pressure, AP, AIx, and aortic and brachial PWV all increased significantly with age; however, the a

75 ortic pulse wave velocity (PWV) and brachial PWV to evaluate the stiffness gradient [(brachial PWV/ao

76 Aortic and brachial PWV were also determined in a subset of 998 subjects.

77 o evaluate the stiffness gradient [(brachial PWV/aortic PWV)(0.5)] and ascending aortic and aortic bi

78 pectively; P=0.046) and higher brachioradial PWV (9.17+/-3.1 versus 8.06+/-1.9 m/s, respectively; P=0

79 time of repair was related to brachioradial PWV (r=0.42, P=0.002) but not to brachial FMD or NTG.

80 Higher aortic stiffness assessed by PWV is associated with increased risk for a first cardio

81 cf-PWV and AI were independently associated with age, sex,

82 CF-PWV was a significant independent predictor of incident

83 pulmonary hypertension, and priapism, and cf-PWV was associated with microalbuminuria.

84 The association between CF-PWV and incident HF persisted after adjustment for systo

85 After adjustment for these correlates, cf-PWV and AI were associated with the glomerular filtratio

86 Mean cf-PWV was lower in SCD patients (7.5+/-2.0 m/s) than in co

87 The clinical and biological correlates of cf-PWV and AI were investigated by using a multivariable mu

88 the hazard ratios for the middle and top CF-PWV tertiles were 1.95 (95% confidence interval, 0.92-4.

89 tios among subjects in the middle and top CF-PWV tertiles were 2.33 (95% confidence interval, 1.37-3.

90 e of carotid-femoral pulse wave velocity (cf-PWV) and augmentation index (AI) at a steady state.

91 Carotid-femoral pulse wave velocity (CF-PWV; the gold standard index of large artery stiffness),

92 ly infused ET-1 did not significantly change PWV compared with infusion of saline (change of -0.08 +/

93 Estimates of heritability (h(2)) of cPP, PWV, P1, and DeltaP(aug) were 0.43, 0.34, 0.31, and 0.62

94 validation, TONO was performed to determine PWV between the carotid and femoral artery.

95 ween carotid and femoral points to determine PWV.

96 Carotid-femoral PWV was measured using the same system.

97 Brachial artery FMD, carotid-femoral PWV, central AIx, and blood pressure (BP) were measured

98 crease in central stiffness (carotid-femoral PWV, P = .001; heart-femoral PWV, P = .004) was linked w

99 e central (carotid-femoral and heart-femoral PWV), peripheral (femoral-ankle PWV), and mixed (brachia

100 carotid-femoral PWV, P = .001; heart-femoral PWV, P = .004) was linked with increases in Abeta deposi

101 meters (P = .45 for diameter and P = .55 for PWV) between stable aneurysms (n = 12) and unstable aneu

102 resence of the metabolic cluster had greater PWV (b = 0.20, 95% confidence interval [CI] 0.01 to 0.38

103 rol subjects (heavier individual with higher PWV), whereas group 1 showed the opposite (negative) int

104 A 4-kg/year higher PWV was associated with a 1.87-cm (95% confidence interv

105 However, PWV and the AIx were not significantly different between

106 fusion of ET-1 significantly increased iliac PWV by 12 +/- 5% (mean +/- STD; p < 0.001), whereas infu

107 nomethyl-L-arginine (L-NMMA) increased iliac PWV significantly, by 3+/-2% (P<0.01).

108 younger individuals, whereas the changes in PWV were more prominent in older individuals.

109 ding diabetes accentuated the differences in PWV seen between groups (controls vs. CKDu vs. CKD: 6.7

110 crease in AoD (P < .0001) and an increase in PWV (P < .0001).

111 fine particles and PM2.5, and an increase in PWV and augmentation index with NO2 and ultrafine partic

112 sult in an age-related, regional increase in PWV primarily affecting the proximal aorta.

113 ion (hazard ratio 1.10 per 1 m/s increase in PWV, 95% confidence interval 1.00 to 1.30, p = 0.03) in

114 Each 1 m/sec increase in PWV, up to 12 m/sec, was associated with mortality, haza

115 aortic stiffness, as indicated by increased PWV, is evident in HCM patients, and is more pronounced

116 sk" metabolic cluster did not have increased PWV or AI@75.

117 lder group displayed significantly increased PWV in the region spanning the ascending and proximal de

118 In addition, exogenous ET-1 increases PWV, and this can be blunted by ET(A) receptor blockade.

119 Both TTTS groups showed marked intertwin PWV discordance, unlike MCDA control subjects.

120 t, posterior tibial FMD, NTG, and lower limb PWV were comparable.

121 r flavone intake was associated with a lower PWV (-0.4 +/- 0.2 m/s for quintile 5 compared with quint

122 Controls had a lower PWV compared to subjects with CKDu and CKD.

123 renal dysfunction, CKDu subjects had a lower PWV than those with CKD (8.7 +/- 1.5 vs. 9.9 +/- 2.2 m/s

124 and berry intake was associated with a lower PWV, no associations were observed for total and other f

125 nges in any of the primary outcome measures (PWV changed by +9.5% and +6.0%, F2-isoprostanes changed

126 By stepwise Cox proportional hazards models, PWV was an independent predictor of incident hypertensio

127 Moreover, PWV and AI are associated with several SCD clinical comp

128 aorto-femoral tapering (p < 0.0001) but not PWV.

129 and SBP predicted mortality; the addition of PWV independently predicted all-cause and cardiovascular

130 In-plane PCMRI permits determination of PWV in multiple aortic locations in a single acquisition

131 imal arterial diameters, and, independent of PWV, is a major determinant of cPP.

132 ilation of muscular arteries, independent of PWV.

133 e in AP, with no significant change in P1 or PWV but an increase in large artery diameters of 4% to 1

134 The PCMRI PWV was measured in three aortic segments.

135 When PCMRI PWV was averaged over the three locations, it was not di

136 Previously, PWV has been measured at a single aortic location, or ha

137 ea (P = .073), and sex (P = .005), pulmonary PWV demonstrated an independent positive association wit

138 Conclusion Pulmonary PWV is reliably assessed with cardiac MR imaging.

139 The repeatability coefficient for pulmonary PWV was 0.96.

140 Increases in pulmonary PWV and RVEF were associated with increases in age (r =

141 The association of pulmonary PWV with RV function and mass was quantified with univar

142 ptor antagonist BQ-123 significantly reduced PWV by 12 +/- 4% (p < 0.001).

143 cetylcholine and glyceryl trinitrate reduced PWV significantly, by 6+/-4% (P=0.03) and 5+/-2% (P<0.01

144 he standard deviation of the high-resolution PWV was significantly higher (P < .001/12) in unstable a

145 nt was independently associated with child's PWV.

146 S reference diet, the geometric mean (+/-SD) PWV was 7.67 +/- 1.62 m/s, and mean percentages of chang

147 years old, the younger group showed similar PWV at each aortic location.

148 ease in E/A, and increased aortic stiffness (PWV: 6.36 +/- 0.47 vs.4.89 +/- 0.41, OSED vs. YSED, P <

149 mixed effects regression models showed that PWV was an independent determinant of the longitudinal i

150 This suggests that PWV could help identify normotensive individuals who sho

151 The PWV discordance seen in laser treated twin pairs resembl

152 The PWV improved model discrimination with an increase in Ha

153 The PWV is a strong risk factor for mortality in KTRs.

154 1 was significantly positively correlated to PWV (p < 0.0001); AP was correlated to aorto-femoral tap

155 (MAP), and CRP were independently related to PWV, and that age, MAP, CRP, sex, and heart rate were as

156 Of 1497 KTRs, 1040 (69%) had a valid PWV measurement.

157 shift in the resonant Peak Wavelength Value (PWV) that is detectable with <10 pm wavelength resolutio

158 s where the column precipitable water vapor (PWV) is less than 1 mm.

159 e of 54.9% +/- 2.5) and pulse wave velocity (PWV) (decrease of 1.3 m/sec +/- 0.8).

160 c resonance measures of pulse wave velocity (PWV) and aortic distensibility (AoD) in the thoracic aor

161 s indices [i.e., aortic pulse wave velocity (PWV) and augmentation (AGI) of carotid arterial pressure

162 ic blood pressure (BP), pulse wave velocity (PWV) and augmentation index (AIx) were assessed in 130 s

163 FVC]) and a decrease in pulse wave velocity (PWV) and augmentation index up to 26 h after the walk.

164 We measured aortic pulse wave velocity (PWV) and brachial PWV to evaluate the stiffness gradient

165 ffness [carotid-femoral pulse wave velocity (PWV) and carotid augmentation index (AI)].

166 Aortic pulse wave velocity (PWV) and carotid augmentation index were reduced only wi

167 ce as assessed by using pulse wave velocity (PWV) and central augmentation index (AIx).

168 s in carotid to femoral pulse wave velocity (PWV) and plasma 8-isoprostane F2alpha-III concentrations

169 Pulse wave velocity (PWV) and the augmentation index (AIx) were assessed noni

170 ured by carotid-femoral pulse wave velocity (PWV) and total arterial compliance.

171 ested this by examining pulse wave velocity (PWV) in brachial arteries of twin survivors of TTTS trea

172 suggested that AIx and pulse wave velocity (PWV) increase linearly with age, yet epidemiological dat

173 resonance imaging (MRI) pulse wave velocity (PWV) measurements.

174 fness was determined by pulse-wave velocity (PWV) of the brachioradial and femoral-dorsalis pedis tra

175 Higher pulse wave velocity (PWV) reflects increased arterial stiffness and is an est

176 Pulse wave velocity (PWV) was calculated by the foot-to-foot methodology from

177 Pulse wave velocity (PWV) was calculated using the foot-to-foot methodology f

178 Pulmonary pulse wave velocity (PWV) was determined by the interval between arterial sys

179 Pulse wave velocity (PWV) was measured in the central (carotid-femoral and he

180 Pulse wave velocity (PWV) was measured invasively (aortic PWV).

181 tic modulus (Einc), and pulse wave velocity (PWV) were measured over a TP range from 0 to 100 mm Hg.

182 sive increase in aortic pulse wave velocity (PWV) with age.

183 ness measured by aortic pulse wave velocity (PWV), 2) oxidative stress assessed by total plasma F2-is

184 ght to evaluate whether pulse wave velocity (PWV), a noninvasive index of arterial stiffness, is a pr

185 (FMD), carotid-femoral pulse wave velocity (PWV), and aortic augmentation index (AIx).

186 P), augmentation index, pulse wave velocity (PWV), and intima-media thickness.

187 yceride content, aortic pulse wave velocity (PWV), and visceral fat.

188 easures, generally from pulse-wave velocity (PWV), are widely used with little knowledge of relations

189 rotid artery (CCA-IMT), pulse wave velocity (PWV), augmentation index, blood pressure (BP), and vascu

190 d pressure (BP), aortic pulse wave velocity (PWV), B-mode ultrasonography and wave form analysis of t

191 blood pressure, aortic pulse wave velocity (PWV), brachial artery flow-mediated dilation (FMD), and

192 ness was assessed using pulse wave velocity (PWV).

193 easured carotid-femoral pulse wave velocity (PWV; SphygmoCor apparatus) 8 weeks after transplantation

194 ght velocity (PHV) and peak weight velocity (PWV) in infancy were derived from parametric growth curv

195 tile range increase in peak weight velocity (PWV), the risk of asthma increased significantly (adjHR:

196 of arterial stiffness (pulse wave velocity [PWV] and augmentation index corrected for heart rate [AI

197 terial stiffness (using pulse wave velocity [PWV]) and arterial diameters (using ultrasonography) wer

198 ral arterial stiffness (pulse wave velocity [PWV]) and arterial diameters, and their respective herit

199 ess (carotid to femoral pulse wave velocity [PWV]) was measured and peripheral blood CD4+CD28- T cell

200 distensibility and arch pulse wave velocity [PWV]), and LV volumes and mass.

201 to arterial stiffness (pulse wave velocity [PWV]), wave reflection (augmentation index, carotid-brac

202 ) and aortic stiffness (pulse wave velocity; PWV) were evaluated before and after exercise training o

203 In healthy volunteers, PWV and augmentation index were associated both with bla

204 PWV and AGI decreased to a nadir at 6 weeks [PWV to 74.2 +/- 4.4% of baseline (B), P = 0.007; AGI to

205 particles that was inversely associated with PWV (P < 0.001).

206 ndrome (inverse) displayed associations with PWV only after BMI was accounted for.

207 aP(aug) did not independently correlate with PWV but independently negatively correlated with the rat

208 portion of CD4+CD28- T cells correlated with PWV (r=0.408, p=0.035).

209 gly independently positively correlated with PWV (standardized regression coefficient, beta = 0.4, p

210 ot significantly associated with PHV or with PWV (adjOR: 1.07; CI: 0.64-1.77 and adjOR: 1.11; CI: 0.6

211 In a subgroup with PWV data, net improvements were observed [flavonoid (n =