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1 Po and merosin are required for normal myelination in th
2 Po fat ingestion rapidly induces insulin resistance by r
3 Po vein insulin delivery, or strategies that mimic it (i
4 Po(gamma) curves had the midpoint at 5.5 +/- 0.1 dyne/cm
7 s between environmental exposure to (2)(1)(0)Po and human health effects were identified in a literat
9 evaluate environmental exposure to (2)(1)(0)Po and the biological effects of low-dose exposure to it
10 The radionuclide grandparents of (2)(1)(0)Po are common in sediments, and segments of the public m
11 hronically exposed to low levels of (2)(1)(0)Po in drinking water or in food products from animals ra
16 itivity and tendency to concentrate (2)(1)(0)Po, the ovary may be the critical organ in determining t
19 0.03 Po, 0.59 +/- 0.03 Po, and 0.65 +/- 0.02 Po were 197 +/- 35 ms, 184 +/- 35 ms, and 179 +/- 22 ms.
20 half-times for relaxation from 0.36 +/- 0.03 Po, 0.59 +/- 0.03 Po, and 0.65 +/- 0.02 Po were 197 +/-
21 axation from 0.36 +/- 0.03 Po, 0.59 +/- 0.03 Po, and 0.65 +/- 0.02 Po were 197 +/- 35 ms, 184 +/- 35
22 1 association with oxygen of 0.209 sec(-1) + Po(2) 2.07 x 10(-4) sec(-1)/mm Hg at 37 degrees C, and a
24 nsP3], ATP had dramatic effects on mInsP3R-2 Po, but unlike the rInsP3R-1, this did not occur by alte
25 d Am) for long-lived polonium isotopes ((208)Po, (209)Po, (210)Po) are effectively removed during pro
26 long-lived polonium isotopes ((208)Po, (209)Po, (210)Po) are effectively removed during processing.
32 sequential determination of (90)Sr and (210)Po in food samples using ultra low-level liquid scintill
33 f stable strontium as yield tracer, and (210)Po is determined through self-deposition using (209)Po a
37 able to detect the radiation emitted by (210)Po, an atypical clinical course prompted active consider
38 y the naturally occurring alpha-emitter (210)Po and that Fukushima-derived doses were three to four o
40 its on radionuclides in foods including (210)Po and (90)Sr, two of the most important radionuclides f
42 ent's death established the presence of (210)Po at concentrations about 10(9)-times higher than norma
48 ured amounts and tissue distribution of (210)Po, it was estimated that the patient had ingested sever
51 alpha-particle-emitting radiochemical ((210)Po-citrate) and 2 anticancer drugs (daunomycin and doxor
52 food products of vegetable origin, the (210)Po activity concentration follows the trend: leafy veget
54 The committed effective doses due to (210)Po from ingestion of honey for infants, children and adu
57 re determined by alpha ((235)U, (238)U, (210)Po, (232)Th and (228)Th) and gamma spectrometry ((137)Cs
59 e-pCa relationship for forces less than 0.50 Po (maximum Ca2+-activated force), i.e. the Hill coeffic
60 ates from steady-state forces less than 0.50 Po was also observed when bundles of fibers were bathed
61 -2 s-1) and constant up to approximately 50% Po, then rising sharply to a maximum (16 +/- 0.8 s-1) in
67 velocity, functional capillary density, and Po(2) in arterioles, venules, and extravascular tissue.
71 n Arabidopsis ecotypes Col-0 (resistant) and Po-1 (susceptible) revealed segregation of more than one
74 itions ( approximately 5 microM; channels at Po approximately 0.3) but not under diastolic Ca(2+) con
75 ith dATP, Vu was 25% greater than control at Po and was elevated at all P > 0.15Po, whereas Po was un
76 nnel open probability in the absence of ATP (Po(zero)) and a correlated decrease in sensitivity to in
79 study conducted at Sannazzaro de' Burgondi (Po Valley), Italy, specifically aimed at optimizing the
81 Bmp and CaMKII increased L-type Ca2+ channel Po in a non-additive manner, suggesting that low and hig
86 in part due to an increase in single channel Po and that the cytoplasmic tails of the beta- and gamma
87 s, has a significantly higher single channel Po compared to the wild-type channel (0.85 vs 0.60, resp
88 these (Ca2+-free) conditions, single-channel Po showed both voltage-dependent and voltage-independent
91 also significantly higher, whereas choroidal Po(2) was significantly lower in the photocoagulated ret
95 xygen tension and consequently increased CSF Po(2) resulting from administration of high Fio(2) durin
97 o the conclusion that the mutation decreases Po by perturbing the gating conformational changes in CF
98 conclusion that the R117H mutation decreases Po by perturbing the gating conformational changes in CF
99 h elevated particulate Po (Po(p)): dissolved Po (Po(aq)) ratios in the cultures, consistent with effi
100 physiology to demonstrate that LP and dorsal Po cells exhibit a variety of responses to simple visual
101 responsive neurons across the LP and dorsal Po whose properties align with some of the established f
102 the open probability (Po.) is reversed, i.e. Po. increases as temperature is lowered whereas under hy
105 We found that Ang II acutely increases ENaC Po, whereas prolonged exposure to Ang II also induces tr
107 None of the enteric caliciviruses except Po/Sapo/GIII/Cowden/80/US replicates in cell culture, wh
109 oped less average peak Ca2+ activated force (Po) during fixed-end contractions (0.78 +/- 0.02 vs. 0.9
113 f the thalamus: the posterior nuclear group (Po), and a region located at the interface of the centra
114 us dog, insulin was infused into the hepatic Po vein or a peripheral (Pe) vein at a rate four times o
115 ry into both mode 1(low Po) and mode 2 (high Po) gating states and that these gating impairments can
118 channels produced no significant changes in Po, nor did it restore the ability of RyRs to respond to
121 rated that mutant channels had a decrease in Po with 0.16 +/- 0.03 versus 0.67 +/- 0.07 for wild type
123 de that the functional defect (a decrease in Po) of DeltaF508-CFTR is as important as the trafficking
124 prevented the genistein-induced decrease in Po, but was without effect on the genistein-induced decr
126 microM Ca2+o had a 5- to 6-fold increase in Po which was accompanied by increases in both open times
127 in protocol 1 and fell faster in Pe than in Po, reaching 41 +/- 3 vs. 67 +/- 2 mg/dL (P < 0.01) by 6
128 the single channel currents had an increased Po compared to negative potentials which was associated
129 ogue 1-oleoyl-2-acetyl-sn-glycerol increased Po, but phorbol 12,13-dibutyrate, which stimulates prote
133 at high altitude because of the low inspired Po(2), which is caused by the reduced barometric pressur
134 oelectrodes were used to record intraretinal Po(2) profiles from healed photocoagulation lesions in a
135 ur main result that HONO in the investigated Po Valley region is mainly from a gas-phase source that
140 mutation impedes entry into both mode 1(low Po) and mode 2 (high Po) gating states and that these ga
141 acic aorta from both rabbit and mouse at low Po(2) (approximately 1% O(2)) but not at high Po(2) (app
143 odel provided a better discrimination of low Po(2) than the tissue-to-plasma ratio or the k(3) of the
146 inhibitory peptide equalized TG and WT LTCC Po and eliminated EADs, whereas a peptide antagonist of
148 nnels was 0.13 +/- 0.02, with a half-maximal Po potential (Vo) of -28.7 +/- 1.4 mV for control record
150 ylinositol (4)5-kinase increased the maximal Po of both Kv7.2 and Kv7.2/7.3 channels studied in on-ce
151 on of muscarinic agonist reduced the maximal Po of Kv7.2/7.3 channels isolated in on-cell patches.
155 was calibrated in water phantoms at multiple Po(2) and temperature conditions (n = 10) and in ex vivo
158 l portions of the posterior thalamic nuclei (Po), multisensory processing of information related to a
161 n calcium-ascending protocols (54% vs. 3% of Po, the force at pCa 6.0) (force hysteresis); the levels
166 The other resistance-determining genes of Po-1 can function, however, as they successfully conferr
167 nd RyR2 (sheep) with a maximal inhibition of Po (Emax) to 52 +/- 4% of control only after adding phys
168 3 currents was due to a strong inhibition of Po and a moderate suppression of single channel conducta
170 drolysis data, we proposed that recycling of Po in vegetative biomass residues is an important mechan
172 ncreased the probability of channel opening (Po) sixfold, which was associated with an increase in th
174 ative potentials the probability of opening (Po) was low and the open time distributions were describ
178 troretinography (ERG) and preretinal oxygen (Po(2)) measurements were obtained 3 to 5 days before sur
184 ates exponentially with elevated particulate Po (Po(p)): dissolved Po (Po(aq)) ratios in the cultures
185 s and properties of soil organic phosphorus (Po) largely drive ecosystem productivity with increasing
186 evated particulate Po (Po(p)): dissolved Po (Po(aq)) ratios in the cultures, consistent with efficien
187 exponentially with elevated particulate Po (Po(p)): dissolved Po (Po(aq)) ratios in the cultures, co
194 stablished multisensory features: posterior (Po), suprageniculate (Sg), limitans (Lim), and medial pu
195 gher-order neurons located in the posterior (Po), lateral posterior (LP), and lateral dorsal (LD) nuc
197 DeltaF508-CFTR targeting) and potentiator ("Po", normalizing DeltaF508-CFTR channel gating) activiti
201 5 mM increased the open channel probability (Po) of native RyRs in SR vesicles, but not of purified R
202 se normally had a very low open probability (Po < 0.1), which, however, showed a dramatic and reversi
203 pproximately 13-fold lower open probability (Po ), were found with the R117H mutation that is associa
205 Delta33 showed an enhanced open probability (Po = 0.6 at -60 mV) and a reduced ATP sensitivity (Ki, 8
206 KATP channels had a higher open probability (Po = 0.7) and a lower ATP sensitivity (Ki = 196 microM)
207 ases the intrinsic channel open probability (Po(0)), thereby indirectly producing a marked decrease i
208 ctance, maximal achievable open probability (Po) and the [Ca2+] required for activation and inhibitio
209 lationship between channel open probability (Po) and Vj was well described by a Boltzmann relationshi
214 L- and N-type Ca2+ channel open probability (Po) in cell-attached patches that contained a single cha
215 do not change the channel open probability (Po) in the absence of ATP, supporting the involvement of
217 switch from sustained high open probability (Po) long open time behaviour to extremely low Po, short
219 enantiomers increased the open probability (Po) of human CFTR, suggesting that bromotetramisole may
221 of red cell membranes, the open probability (Po) of the Gardos channel is markedly reduced when the t
222 onists, the single-channel open probability (Po) of the phenylalanine 508-deleted cystic fibrosis tra
223 >/=5 microM) increased the open probability (Po) of very active ("high-activity") RyR1 of SkM reconst
224 minal Ca(2+) dependence of open probability (Po) over the physiologically relevant range (0.05-1 mM C
225 (P-dATP), can increase the open probability (Po) to approximately 0.7, implying that the gating defec
226 evel, i.e., an increase in open probability (Po), and second, these C-terminal regions of beta- and g
234 wed us to obtain a maximum open probability (Po,max) value for the extrasynaptic receptors (Po,max =
235 perature dependence of the open probability (Po.) is reversed, i.e. Po. increases as temperature is l
237 activate EADs, and LTCC opening probability (Po) was significantly higher in TG than WT cardiomyocyte
239 ic (L596A/G/W/Q/K) reduces open probability [Po; loss-of-function (LOF)], likely due to altered inter
245 yperoxia increased the average inner retinal Po(2) (P(IR)) in the detached retina to a level higher t
249 o the luminal side of purified channels, RyR Po increased significantly; however, the channels still
251 The findings that individual dura-sensitive Po, LP, and LD neurons project to many functionally dist
253 T channel had indistinguishable steady-state Po values, ATP dose-response relationships and single-ch
255 s studies have shown that isometric tension (Po) decreases linearly in the logarithm of [Pi] for [Pi]
257 conformation of Hb to tissue oxygen tension (Po(2)) and thereby provide a basis for the graded vasodi
259 the peak isometric twitch (Pt) and tetanic (Po) tensions, as well as fatigability during 5 secs of n
261 educed by increasing temperature, as are the Po values of inside-out patches of Chinese hamster ovary
267 ics indicated that Ca2+ and ATP modulate the Po predominately by facilitating extended bursting activ
271 acterize the suburban and rural areas of the Po Valley and of other many populated environments.
273 a large body of evidence indicates that the Po(2)-coupled allosteric transition from R (oxy)-state t
274 s with cloned RPS2 alleles revealed that the Po-1 allele of RPS2 can function in a Col-0 genetic back
278 equence in Bay of Hangzhou (China) for their Po composition using solution (31)P-NMR after NaOH-EDTA
280 and voltage-independent components in their Po/V relationship) show points of resemblance to those e
283 dolateral part of PPC (PtP) also projects to Po but can be distinguished from lPPC based on architect
290 ging protocol to image quantitative vitreous Po(2) noninvasively and evaluated effects from vitreal m
296 ble to those observed before disuse, whereas Po/CSA and unloaded shortening velocity reached a higher
297 at, although PPC subareas are connected with Po and medial LP, the medial and lateral secondary visua
299 otential new genogroup of porcine SaVs, with Po/SaV/OH-JJ681/00/US as the representative strain.
301 lucose fell faster with Pe insulin than with Po insulin, reaching 56 +/- 3 vs. 70 +/- 6 mg/dL (P = 0.
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