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1 ccompanying paper that mes-6 encodes another Polycomb group protein.
2 mes-2 encodes another Polycomb group protein.
3 also involved in epigenetic silencing by the Polycomb group proteins.
4 even in the presence of normal levels of all Polycomb group proteins.
5 al repressors: the gap gene products and the Polycomb group proteins.
6 silencing is mediated, at least in part, by Polycomb Group proteins.
7 Both silencing activities depend upon Polycomb Group proteins.
8 genes previously epigenetically silenced by Polycomb group proteins.
9 of chromatin-remodeling complexes, including Polycomb group proteins.
10 glycosylases and repressive targeting by the Polycomb group proteins.
11 lation of histone H3 on lysine 27 (H3K27) by Polycomb group proteins.
12 paternal and maternal genomes as well as by Polycomb group proteins.
13 H3 at lysine 27 (H3K27me) as directed by the Polycomb group proteins.
14 core ES transcriptional circuitry, including Polycomb group proteins.
15 tions, expanding the regulatory diversity of polycomb group proteins.
16 homologs of the Drosophila chromatin-binding Polycomb-group proteins.
17 e been identified that mediate the action of Polycomb-group proteins.
18 ber of transcriptional repressors, including Polycomb-group proteins.
19 complex 1 (PRC1) comprise a core assembly of Polycomb group proteins and additional factors that incl
21 chromatin states mediated by the Drosophila Polycomb group proteins and is physically associated wit
22 t that, contrary to the prevailing view, the Polycomb group proteins and methyltransferase complexes
23 se genes are subjected to repression by both Polycomb group proteins and SetDB1, and loss of either r
25 ypermethylation, recruitment, and binding of polycomb-group proteins, and histone heterochromatin mod
37 a link between an Abd-type Hox protein and a Polycomb group protein at the level of direct protein-pr
38 ver faster at sites for trithorax-group than polycomb-group protein binding, suggesting that nucleoso
45 suggest, more generally, that Trithorax and Polycomb group proteins can cooperate with one another t
51 sferase EHMT2 (also known as G9A) or for the Polycomb group protein EED, involved in repressive H3K9m
56 through gene expression profiling, that the polycomb group protein enhancer of zeste homolog 2 (EZH2
57 ast cancer with heightened expression of the Polycomb group protein Enhancer of Zeste Homolog 2 (EZH2
61 encodes a protein similar to the Drosophila Polycomb group protein, Enhancer of zeste, and in the ac
63 otein, a mammalian homolog of the Drosophila Polycomb group protein Esc, as a bait in the yeast two-h
66 en-responsive elements (ARE) and dictated by Polycomb group protein EZH2 and repressive chromatin rem
67 ever, constitutive repression of CCN3 by the Polycomb group protein EZH2 disrupted this negative feed
68 4) in Genes & Development of the role of the polycomb group protein Ezh2 in muscle stem cells, and di
75 inase in FLB1 and a differentially localized Polycomb group protein Ezh2, which is mostly nuclear in
77 ogenesis is to suppress transcription of the Polycomb group protein, EZH2, thereby de-repressing gene
84 ng of DAB2IP is a key mechanism by which the polycomb-group protein histone-lysine N-methyltransferas
87 results predict that the MES proteins, like Polycomb group proteins in Drosophila, function as a com
88 silent set of miRNA genes is co-occupied by Polycomb group proteins in ES cells and shows tissue-spe
90 the importance of histone methylation by the polycomb group proteins in the mouse circadian clock mec
92 sive complex 1-like), is composed of several Polycomb-group proteins including Ring1, Ring2, Bmi1 and
93 ver, we demonstrate that endogenous E2F6 and polycomb group proteins, including RYBP, Ring1, MEL-18,
94 ng protein homologous to Drosophila SFMBT, a Polycomb group protein involved in epigenetic regulation
95 t the H2A-K119 ubiquitin E3 ligase Ring1b, a Polycomb group protein, is enriched on Xi in female trop
96 third thoracic segments, which requires the Polycomb group proteins, is disrupted by most chromosoma
97 miR-16 levels down-regulated BMI1 and other polycomb group proteins like RING1A, RING1B, EZH2 and al
99 by histone deacetylases and that mediated by polycomb group proteins may act either independently or
101 s provide a framework for an RNAi-dependent, Polycomb group protein-mediated heterochromatin formatio
102 trimethylation (H3K27me3) has been linked to polycomb-group-protein-mediated suppression of Hox genes
104 is study investigates the effect of Bmi-1, a polycomb group protein, on radiation-induced senescence
105 racterisation indicates that MEDEA encodes a Polycomb-group protein, particularly intriguing as MEDEA
106 ction of methylation-prone genes compared to Polycomb group protein (PcG) marking in embryonic stem c
107 m chromatin and found candidates that impact polycomb group protein (PcG)-regulated gene expression i
108 ue of Molecular Cell) have demonstrated that Polycomb group proteins (PcG) and the Kcnq1ot1 regulator
118 eversible chromatin interactions mediated by Polycomb-group proteins play an important role in these
121 g activity depends on a binding site for the Polycomb-group protein Pleiohomeotic (Pho) and on pho ge
122 e interaction between the SAM domains of the polycomb group proteins polyhomeotic (Ph) and Sex-comb-o
126 tioning in Arabidopsis thaliana We show that Polycomb-group proteins repress nucellus degeneration be
127 rotein interacts directly with E(Z), another Polycomb Group protein required for silencing of the hom
131 results indicate that combined modulation of polycomb group proteins, such as EZH2, along with TrxG p
132 The products of these genes are similar to Polycomb group proteins, suggesting possible mechanisms
133 es are a subset of those described for other Polycomb-group proteins, suggesting that E(Z) may also p
134 epress reporter gene expression and bind the Polycomb group protein SUZ12 and the DNA methyltransfera
135 strated that RA-mediated displacement of the polycomb group protein SUZ12 from a RARE was inhibited i
136 s including age-specific hypermethylation in polycomb group protein target genes and the upregulation
141 was correlated with higher levels of Bmi1, a polycomb group protein that is known to regulate the Ink
143 ransferase, Ezh2 (enhancer of zeste 2), is a Polycomb group protein that plays important roles in man
145 of bmi-1 is homologous to certain Drosophila Polycomb group proteins that regulate homeotic gene expr
147 lated by trans-acting factors related to the Polycomb-group proteins that have long been known as reg
148 e range of action of repressors, such as the Polycomb group proteins, throughout the euchromatic regi
149 Since E(Z) is required for binding of other Polycomb Group proteins to chromosomes, these results su
151 adian rhythms and extend the activity of the polycomb group proteins to the core clockwork mechanism
152 ransferases and repressing proteins, such as Polycomb group proteins; upon differentiation, DNMT acti
153 ensitive silencing are related properties of Polycomb-group proteins, whereas their activities are ge
154 on the mechanism of histone modification via Polycomb Group Proteins, which evolved in tandem with th
155 ereas VRN2 encodes a homologue of one of the Polycomb group proteins, which maintain the silencing of
156 he mark trimethyl H3K27, we examined whether Polycomb group proteins, which methylate H3K27, were pre
157 ppression as an alternative to regulation by Polycomb-group proteins, which coordinate embryonic germ
158 g how these configurations are stabilized by Polycomb group proteins will advance our understanding o
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