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1 QALYs were generated from overall survival and patients'
3 below the range of Can$20 000 to Can$100 000/QALY and below US$50 000/QALY, thresholds generally used
9 000 to Can$100 000/QALY and below US$50 000/QALY, thresholds generally used to evaluate the cost-eff
11 -effective in 70% of iterations at a $50,000/QALY threshold and 65% of iterations at a $100,000/QALY
13 sfunction (all with ICERs $50,000 to $70,000/QALY gained), patients age <75 years (ICER = $44,779/QAL
16 0 [range pound35,300-61,400] and pound48,000/QALY [ pound34,600-74,800], respectively) and, in specia
17 years, respectively, standard error = 0.005 QALY), at increasing average costs: US$3445 (annual moni
29 fter 3 years, surgery led to a gain of 0.199 QALYs compared with no surgery at an incremental cost of
35 hly cost-effective ($27 863/QALY and $19 302/QALY, respectively) relative to status quo and at a US w
36 Petrolatum was the most cost-effective ($353/QALY [95% CI, $244-$1769/QALY) moisturizer in the cohort
39 ce between the mean QALYs was 4.7 days (46.4 QALY days for the OSC plus WBRT group vs 41.7 QALY days
50 Results: Standard management yielded 9.6 QALYs and accrued $155261 in lifetime costs, while inten
55 ALY days for the OSC plus WBRT group vs 41.7 QALY days for the OSC group), with two-sided 90% CI of -
56 idered non-inferior if it was no more than 7 QALY days worse than treatment with WBRT plus OSC, which
57 ss than 8 h, inexpensive with a ICER of $8.7/QALY, and affordable in developing countries and area wh
60 ned), patients age <75 years (ICER = $44,779/QALY gained), and patients with peripheral artery diseas
64 ence, and are highly cost-effective ($27 863/QALY and $19 302/QALY, respectively) relative to status
66 remental cost effectiveness ratio of $90,871/QALY, and first-line NIVO + IPI followed by carboplatin
73 2 +/- 212.15 for the anti-VEGF group, with a QALY gain of 0.21, the yearly mean cost was euro7153.62
75 , 0.69 additional life-year, 0.62 additional QALY, and $29 203 in incremental costs, equating to a co
76 frameworks) and criterion validity (against QALYs from the National Institute for Health and Care Ex
85 r low-income contexts achieved 6.142 average QALYs at a cost of US$3524, similar to the fixed 12-mont
87 a probability of 84% to 98% that cumulative QALYs were higher and a probability of 91% to 99% that c
88 oup had a probability of 96% that cumulative QALYs were higher and cumulative costs were lower than i
90 1.01, 95% CI 0.86-1.19; p=0.95) or economic (QALY: mean difference 0.006, -0.009 to 0.02; p=0.42) out
92 -income resource settings yields 0.008 fewer QALYs per person, but saves US$204 compared to monitorin
93 associated with increased cost and improved QALY: incremental cost, $105398; incremental QALY, 0.39,
94 ould result in increases as follows: 0.77 in QALY per patient with any-DR and 0.6 and 0.44 per patien
95 , the combination of the small difference in QALYs and the absence of a difference in survival and qu
98 Both screening strategies produced a gain in QALYs, resulting in incremental cost-effectiveness ratio
100 and 55.4% when effectiveness was measured in QALYs for total costs and 31.3% and 34.3%, respectively,
101 ative care- 1,169,121 Thai baht) and more in QALYs (peg 2a- 13.44 vs. peg 2b- 13.14 vs. palliative ca
103 ILI in obese patients (with F0-F3) increased QALYs by 0.678-2.152 and 0.452-0.618, respectively, comp
106 ght patients (with F0-F3), surgery increased QALYs by 0.050-0.824 and ILI increased QALYs by 0.031-0.
107 e; in overweight patients, surgery increased QALYs for all patients regardless of fibrosis stage, but
108 nt thresholds were associated with increased QALYs (0.002-0.004), and only quadrennial screening of p
109 ll strategies were associated with increased QALYs (0.002-0.004), and several strategies were potenti
111 QALY: incremental cost, $105398; incremental QALY, 0.39, with an ICER of $268637 per QALY gained ($16
114 ate would result in 0.15 additional lifetime QALY, but this gain would cost an incremental $77 290, l
116 low cost and a favorable cost-utility (low $/QALY) as a result of the minimization of the cost and mo
119 by $78 257), with patients accumulating more QALYs (by 0.42) than with the observed standard of care.
121 d control was cost-saving and generated more QALYs compared with uniform intensive control, except in
122 first-line therapy provided marginally more QALYs but accumulated substantially higher drug costs.
123 increase in complications but produced more QALYs (16.68 vs. 16.58) due to fewer hypoglycemic events
129 8,158 to -euro190) lower, and mean number of QALYs was 0.116 (95% CI, 0.005 to 0.227) higher in the i
130 y likely to be cost-effective; the number of QALYs was higher and cumulative costs were lower for SC
132 , 0.53 (ASCOv2), and 0.46 (ESMO); with pCODR QALYs, coefficients were 0.19 (ASCOv1), 0.20 (ASCOv2), a
135 willingness-to-pay threshold of $50,000 per QALY and 76 to 93% below the threshold of $100,000 per Q
136 cost-effectiveness ratio of pound22 000 per QALY and a probability of cost-effectiveness of 20%.
137 event 316,300 MACE at a cost of $503,000 per QALY gained compared with adding ezetimibe to statins (8
138 ry 3 years would cost less than $100,000 per QALY gained if the MT-sDNA test achieved a participation
141 s strategies and a threshold of $100,000 per QALY gained, FIT was preferred in 99.3% of iterations in
142 willingness-to-pay threshold of $100 000 per QALY gained, RFA-SBRT was preferred in 65.8% of simulati
149 6 to 93% below the threshold of $100,000 per QALY), regardless of whether treatment effects were redu
151 t-effectiveness threshold of pound15 000 per QALY, the low-risk elderly seasonal vaccination programm
155 US$18,000 (95% CI: US$14,000, US$24,000) per QALY gained, 50% NSP coverage could avert up to 35,000 (
156 US$25,000 (95% CI: US$7,000, US$76,000) per QALY gained, 50% Test & Treat coverage could avert up to
157 US$27,000 (95% CI: US$15,000, US$48,000) per QALY gained, and 50% PrEP coverage could avert up to 37,
160 cost-effectiveness threshold of $100000 per QALY compared with bevacizumab during a 10-year horizon;
162 o 4 years, the ICER decreased to $114078 per QALY and became cost-effective by 5 years with an ICER o
163 Evolocumab treatment exceeded $150000 per QALY in most scenarios but would meet this threshold at
167 eening scenarios were $19,600 to $29,200 per QALY, and the respective first-year prison budget was $9
169 er QALY in men and euro18687 (US $20044) per QALY in women for TBSE and euro34836 (US $37365) per QAL
172 was $18239 (95% CI, dominant to $24408) per QALY gained, with dominant indicating that the intervent
173 ntal QALY, 0.39, with an ICER of $268637 per QALY gained ($165689 with discounted price of $10311 bas
174 ICER) was euro6840.75 (95% CI 2545-2759) per QALY gained for a treatment efficacy of 20% and euro4243
177 cost-effectiveness ratio (ICER) of $323 per QALY, and naloxone distribution plus linkage to addictio
178 age to addiction treatment (ICER $95 337 per QALY) at a willingness-to-pay threshold of $100 000.
180 -effectiveness ratio of ECHO was $10,351 per QALY compared with the status quo; >99.9% of iterations
181 tiveness ratios of euro33072 (US $35475) per QALY in men and euro18687 (US $20044) per QALY in women
182 women for TBSE and euro34836 (US $37365) per QALY in men and euro19470 (US $20884) per QALY in women
185 o $488642 per QALY, with ICER of $413579 per QALY for trial patient characteristics and event rate of
187 ed ICERs ranging from $100193 to $488642 per QALY, with ICER of $413579 per QALY for trial patient ch
203 entially cost-effective in terms of cost per QALY (incremental cost-effectiveness ratio, $70831-$1363
204 entially cost-effective in terms of cost per QALY (incremental cost-effectiveness ratio, $92446).
207 ration of improved outcomes, with a cost per QALY gained of $120 623 if the duration was limited to t
215 ion to lifetime therapy yielded the cost per QALY with PRP treatment of $14 219 to $24 005 and with I
223 ate and triple therapy were $2.7 million per QALY and $0.98 million per QALY over 24 and 48 weeks, re
225 cost would be approximately $28,000 more per QALY gained if the treatment effects persisted for the r
226 nd would cost approximately $47,000 more per QALY gained if there were a reduction in adherence and t
229 low common willingness-to-pay thresholds per QALY, regardless of whether benefits were reduced after
230 f S$173 per person) while generating similar QALYs compared with the physician-based model (i.e., 13.
233 the incremental cost-effectiveness values ($/QALY) for each moisturizer in preventing atopic dermatit
234 time horizon, ticagrelor was associated with QALY gains of 0.078 and incremental costs of $7,435, yie
235 SMO-MCBS, as well as their correlations with QALYs and with NICE/pCODR funding recommendations, sugge
236 emental cost per quality-adjusted life year (QALY) and varied model inputs in one-way and probabilist
241 emental cost per quality-adjusted life-year (QALY) gained by additional 9vHPV vaccination was $146 20
242 and the cost per quality-adjusted life-year (QALY) gained, as well as the budget effect, expressed as
243 and the cost per quality-adjusted life-year (QALY) gained, as well as the budget effect, expressed as
244 662-132 452) per quality-adjusted life-year (QALY) gained, pound372 207 (268 162-1 903 385) per death
247 g, mean cost per quality-adjusted life-year (QALY) of screening all admissions was pound89,000-148,00
249 emental cost per quality-adjusted life-year (QALY), and total effect on US health care spending over
250 ovascular death, quality-adjusted life-year (QALY), incremental cost-effectiveness ratio (ICER), and
251 ed as dollar per quality-adjusted life-year (QALY), were calculated with incremental cost-effectivene
254 han $100 000 per quality-adjusted life-year [QALY] gained), while contrast-enhanced MR imaging was fa
255 ( pound2394 per quality-adjusted life-year [QALY]) and the 12-week programme ( pound3804 per QALY).
256 The additional quality adjusted life years (QALY) with intervention was 0.08 (95% CI 0.03 to 0.13),
258 sed to evaluate quality-adjusted life-years (QALY) and incremental cost-effectiveness ratios (ICER) o
260 fit in terms of quality-adjusted life years (QALYs) (0.0325, 95% CI -0.0074 to 0.0724), and on the co
261 ere measured in quality-adjusted life years (QALYs) and incremental cost-effectiveness ratios (ICER).
262 imate costs and quality-adjusted life years (QALYs) comparing between the combination of pegylated in
263 (2016 US$) and quality-adjusted life years (QALYs) for treatment sequences with first-line NIVO, IPI
265 d as discounted quality-adjusted life years (QALYs), costs in U.S. dollars, and cost-effectiveness ex
267 es in survival, quality-adjusted life years (QALYs), costs, and resulting budget impact between ECHO
272 they relate to quality-adjusted life-years (QALYs) and funding recommendations in the United Kingdom
274 uent costs, and quality-adjusted life-years (QALYs) for intensive control versus standard control of
276 ctive number of quality-adjusted life-years (QALYs) gained in the test and no-test option were 61 820
277 was measured as quality-adjusted life-years (QALYs) gained or lost by investing resources in a new st
282 remental costs, quality-adjusted life-years (QALYs), and incremental cost-effectiveness ratios (ICERs
284 d as discounted quality-adjusted life-years (QALYs), costs in US dollars, and cost effectiveness expr
285 spitalizations, quality-adjusted life-years (QALYs), costs, and incremental costs per QALY gained.
286 es: Life-years, quality-adjusted life-years (QALYs), costs, heart failure hospitalizations, and incre
287 fe-years (LYs), quality-adjusted life-years (QALYs), direct medical expenditure, and cost per LY and
289 expectancy and quality-adjusted life-years (QALYs), false-positive mammograms, benign biopsy results
290 ife expectancy, quality-adjusted life-years (QALYs), number and percentage of overdose deaths averted
298 and discounted quality-adjusted life years [QALYs]), and incremental cost-effectiveness ratios (ICER
299 .221 discounted quality-adjusted life-years [QALYs] per patient with monitoring every 24 to 1 month o
300 effectiveness (quality-adjusted life-years [QALYs]), and incremental cost-effectiveness ratios of va
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