ライフサイエンスコーパス: R-cadherin

1 igration is absent in cells expressing E- or R-cadherin.

2 n of nectin complexes and failure to recruit R-cadherin.

3 ial cDNA with extensive sequence homology to R-cadherin.

4 formation of cis-heterodimers between N- and R-cadherins.

5 ll surface adhesion molecules and found that R-cadherin, a calcium-dependent cell-cell adhesion molec

6 of the deep vascular network is mediated by R-cadherin, an adhesion molecule known to be involved in

7 Immunolocalization of R-cadherin and intravitreous injection of R-cadherin-spe

8 Thus, R-cadherin antagonists may be useful in the treatment of

9 Injection of anti-R cadherin antibodies also dramatically affects vessels

10 cubation of HSCs with function-blocking anti-R-cadherin antibodies or novel R-cadherin-specific pepti

11 Furthermore, we show that when N- and R-cadherins are coexpressed in neurons in vitro, the two

12 rescued in vivo by selective replacement of R-cadherin by electroporation into cultured Pax6 mutant

13 of the homophilic cohesion molecules N- and R-cadherin by otherwise noncohesive L929 cells.

14 the expression of the cell adhesion molecule R-cadherin (Cdh4) is lost in Pax6 mutants.

15 In adult zebrafish brain, R-cadherin continued to be expressed in several specific

16 odies was performed to determine the role of R-cadherin during patterning of the superficial and deep

17 While diencephalic progenitors from R-cadherin-expressing regions of prosomere 5 could integ

18 regions of prosomere 5 could integrate into R-cadherin-expressing regions of the cortex, they did no

19 olecule, can now integrate more readily into R-cadherin-expressing regions, such as the cortex, the v

20 In the adult, R-cadherin expression continued in a subpopulation of re

21 Recently, E-, N-, and R-cadherin have been identified as ligands for KLRG1.

22 el retinal ganglion cell axons combined with R-cadherin in situ hybridization to explicitly examine t

23 dy, we show that inappropriate expression of R-cadherin in tumor cells results in decreased expressio

24 rin, E-cadherin, and cadherin-4 (also called R-cadherin) in extracts of rat lung.

25 n), cadherin-2 (N-cadherin), and cadherin-4 (R-cadherin), in the olfactory system of developing and a

26 In addition, we show that R-cadherin induces cell motility when expressed in epith

27 These results demonstrate that R-cadherin is appropriately distributed to play a role i

28 n of E-cadherin in response to expression of R-cadherin is owing to competition for p120(ctn).

29 t a member of the cadherin family (zebrafish R-cadherin) is expressed in retinal ganglion cells, and

30 These results suggest that R-cadherin-mediated adhesion plays a role in development

31 developing retinal vascular layers, blocking R-cadherin-mediated adhesion resulted in mistargeting of

32 ere closely associated with cells expressing R-cadherin message in the hypothalamus, the pretectum, a

33 R-cadherin message increased during embryogenesis up to

34 ofretinal axons and brain regions expressing R-cadherin message.

35 tinal ganglion cells in the embryo expressed R-cadherin message.

36 Injection of antibodies directed against R-cadherin prevents the normally extensive collateraliza

37 Cells coexpressing N- and R-cadherins show homophilic adhesion in which these prot

38 members of this class of adhesion molecules, R-cadherin shows a striking pattern of prosomeric expres

39 of R-cadherin and intravitreous injection of R-cadherin-specific antibodies was performed to determin

40 blocking anti-R-cadherin antibodies or novel R-cadherin-specific peptide antagonists effectively prev

41 In vitro, an R-cadherin substrate promoted pioneer axon outgrowth.

42 w that when A431 cells are forced to express R-cadherin, they dramatically downregulate the expressio

43 mporal expression of this putative zebrafish R-cadherin was examined in embryos and adults by Norther

44 In the retina, R-cadherin was first detected at about 33 hours postfert

45 In the embryonic brain, R-cadherin was first expressed in groups of cells in the

46 genitor integration to prosomeres expressing R-cadherin, we used a retroviral-mediated gain-of-functi

47 rosomere P2 (a region which does not express R-cadherin), when forced to express this molecule, can n