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1                                              RCA formation substantially reduced root respiration and
2                                              RCA fractional flow reserve increased significantly (P=0
3                                              RCA has also attracted significant attention in the fiel
4                                              RCA I injection led to a dose- and time-dependent decrea
5                                              RCA increased the growth of simulated 40-d-old maize pla
6                                              RCA is a linear DNA amplification technique that can use
7                                              RCA vessel wall thickness was significantly increased in
8                                              RCA-amplified protein chips can now profile up to 150 pr
9                                              RCA-based analysis of condyloma specimens from a patient
10                                              RCA-RCA utilizes restriction digestion and whole genome
11 16 patients; LAD was affected in 16 (72.3%), RCA in 14 (63.3%), and LCX in 8 (36.4%) cases.
12 NA) with a linear range spanning 6 (SNA), 7 (RCA), or 8 (Con A) orders of magnitude.
13 ent of sequence identity was not an accurate RCA rate predictor.
14                        The Rubisco activase (RCA) gene from each species was sequenced.
15 n due to the inhibition of Rubisco activase (RCA) under moderately elevated temperatures.
16 e gamma-subunit (AtpC) and Rubisco activase (RCA) were identified by matrix-assisted laser-desorption
17 logical regulators of complement activation (RCA) can attenuate this foreign body-induced activation,
18  of the regulators of complement activation (RCA) gene family.
19         Regulators of complement activation (RCA) inhibit complement-induced immune responses on heal
20 te host regulators of complement activation (RCA) into their viral envelopes and, as a result, escape
21 of host regulators of complement activation (RCA) proteins, suggesting that they have evolved immune
22 o human regulators of complement activation (RCA) that contain tandem short consensus repeats (SCRs).
23 surface regulators of complement activation (RCA) to resist antibody-dependent complement-mediated ly
24 mily of regulators of complement activation (RCA).
25  termed regulators of complement activation (RCA).
26 gs to the regulators of complement activity (RCA) family.
27 ration of regulators of complement activity (RCA) into the viral envelope afforded complement resista
28 earance of replication-competent adenovirus (RCA).
29 ling predicts that root cortical aerenchyma (RCA) could improve N acquisition in maize (Zea mays).
30                    Root cortical aerenchyma (RCA) is induced by hypoxia, drought, and several nutrien
31 he toxic lectin Ricinus communis agglutinin (RCA) I into the sciatic nerve.
32 pe I (SNA), and Ricinus communis agglutinin (RCA) on polycrystalline gold electrodes was optimized an
33 (Con A), 10 fM (Ricinus communis agglutinin (RCA), or 100 fM (SNA) with a linear range spanning 6 (SN
34 ases, including Ricinus communis agglutinin (RCA), saporin, and abrin II.
35  the Ricinus communis ("ricin") agglutinins (RCA(60) and RCA(120)), despite >80% sequence homology be
36                                        Also, RCA allowed the direct quantification of RNA targets at
37 A) technology, rolling circle amplification (RCA) and DNAzymes.
38  that utilizes rolling circle amplification (RCA) and magnetic microbeads as a signal enhancement met
39                Rolling-circle amplification (RCA) and ramification amplification (RAM, also known as
40 ow-temperature rolling circle amplification (RCA) and strand displacement amplification (SDA).
41 t of real-time rolling circle amplification (RCA) for protein targets, we have developed a novel type
42                Rolling circle amplification (RCA) is an isothermal enzymatic process where a short DN
43  the dendritic rolling circle amplification (RCA) is introduced.
44     Isothermal rolling circle amplification (RCA) is used to detect nucleic and non-nucleic acid biom
45 on followed by rolling circle amplification (RCA) labeling of the cleavage products.
46 conditions for rolling-circle amplification (RCA) of individual DNA molecules 5-7 kb in size by >10(9
47 ethod includes rolling-circle amplification (RCA) of repeats in vitro and assembly of the RCA product
48 een applied as rolling circle amplification (RCA) of specific target sequences as well as circular ve
49 on followed by rolling circle amplification (RCA) of the cleavage products.
50 s amplified by rolling circle amplification (RCA) on magnetic particles.
51 ction (PCR) or rolling circle amplification (RCA) processes, taking advantage of real-time amplificat
52 In this paper, rolling circle amplification (RCA) products are detected in solution and on magnetic p
53 NA circle in a rolling circle amplification (RCA) reaction.
54 have performed rolling-circle amplification (RCA) reactions on three DNA templates that differ distin
55 ion (LAMP) and Rolling Circle Amplification (RCA) techniques for c-MYC and BCR-ABL1 genes, allowing f
56 he organelles, rolling circle amplification (RCA) to amplify the genome, and shotgun sequencing to 8x
57 ostructures by rolling circle amplification (RCA) using boranephosphonate internucleotide linkages.
58 n this system, Rolling Circle Amplification (RCA) was used as a signal amplification method for both
59 he stand-alone rolling circle amplification (RCA) with capillary electrophoresis (CE) for specific an
60                Rolling circle amplification (RCA), an isothermal amplification technique that creates
61 ne produced by rolling circle amplification (RCA), which results in increased stability and templated
62 correction and rolling circle amplification (RCA)-based target enrichment to vastly improve NGS-based
63 e obtained via rolling circle amplification (RCA).
64 y ligation and rolling circle amplification (RCA).
65 tectable using rolling circle amplification (RCA).
66 lication using rolling-circle amplification (RCA).
67 substrates for rolling circle amplification (RCA).
68 essfully using Rolling Circle Amplification (RCA).
69 and isothermal rolling circle amplification (RCA).
70 logies such as rolling circle amplification (RCA).
71 on followed by rolling circle amplification (RCA).
72 synthesized by rolling-circle amplification (RCA).
73 ing from the rolling circular amplification (RCA).
74 gaged in a rolling-circle DNA amplification (RCA) reaction.
75            In contrast to PCR amplification, RCA using phi29 DNA polymerase does not produce mutant j
76 mit of detection of 10pM was obtained for an RCA time of 60min.
77 e obtain a limit of detection of 10pM for an RCA time of only 20min corresponding to a total assay ti
78                         Root cause analysis (RCA) is a conventional method used to deal with errors t
79 , we developed reference component analysis (RCA), an algorithm that substantially improves clusterin
80                  Through pull-down analysis, RCA bound predominantly to the region between the methyl
81 lied with multivariate statistical analysis, RCA protein chips have the potential to identify multipl
82  communis ("ricin") agglutinins (RCA(60) and RCA(120)), despite >80% sequence homology between the tw
83 g mechanism, which splices the RCA-alpha and RCA-beta isoforms were probably gained from another gene
84        Pyrosequencing of domain amplicon and RCA PCR products generated 1.5 x 10(6) reads, including
85   Absolute decreases in mid-wall Ecc LAD and RCA and global Ecc were 3.0%, 3.4%, and 2.8%, respective
86 ted with lower (absolute) Ecc in the LAD and RCA regions (regression coefficient 0.37 per unit higher
87         Smokers had lower Ecc in the LAD and RCA regions compared with nonsmokers.
88   In addition, segmental function in LAD and RCA regions was reduced when individuals in the lowest 1
89 n by Ecc was noted (p < or = 0.01 in LAD and RCA territories).
90 abrin II shared one pattern, while ricin and RCA shared a distinct pattern.
91 flexor neck muscle, rectus capitis anterior (RCA), in the adult cat.
92 multaneously compared with a commercial anti-RCA IgG antibody in a multicapture agent, single target
93 variants were introduced into an Arabidopsis RCA deletion (Deltarca) line.
94 rmed 'regulator of chromosome architecture' (RCA), cooperates with condensin to preserve the characte
95 an animal model for repetitive CO2 arousals (RCAs) and investigating the effect of deleting the gene
96 ro studies, porcine right coronary arteries (RCA) and post-confluent (passages 3-6) 5-day, serum-rest
97 ncreased by 60% in the right carotid artery (RCA) and decreased by 80% in the LCA.
98  for the detection of right coronary artery (RCA) and left circumflex artery (LCX) lesions (0.84 +/-
99 g a 1-minute proximal right coronary artery (RCA) and left coronary artery balloon occlusion at basel
100 proximal 40 mm of the right coronary artery (RCA) in 67 and from the proximal 35 mm of the left circu
101     Although proximal right coronary artery (RCA) occlusion is the culprit commonly responsible for a
102 onary sinus, from the right coronary artery (RCA) to the inferior vena cava, and from the RCA to the
103 d to measure proximal right coronary artery (RCA) wall thickness, and multidetector computed tomograp
104 erotic lesions in the right coronary artery (RCA), American Heart Association (AHA) lesion grade in t
105 ry (LAD), then in the right coronary artery (RCA), circumflex branch (LCx) and the left main coronary
106 lex artery (LCX), and right coronary artery (RCA).
107 ctional images of the right coronary artery (RCA).
108  left circumflex, and right coronary artery [RCA]).
109           Here we applied these DNA-assisted RCA techniques in capillary isoelectric focusing to reso
110 fy individual particles with single attached RCA products from blank particles.
111                         The O. australiensis RCA enzyme was thermally stable up to 42 degrees C, cont
112                        A combination of both RCA and PCR provides a wide protein target dynamic range
113 on glass arrays with signal amplification by RCA with high specificity, femtomolar sensitivity, 3 log
114 NA sequence to Dk2, which, once amplified by RCA, codes for a fluorescence generating deoxyribozyme.
115  synthesis of scaffold and staple strands by RCA-based enzymatic reactions allows the generation of D
116 mplification of small amounts of template by RCA using phi29 DNA polymerase is "background" DNA synth
117 ion of small molecular entities that capture RCA with high affinity is an intriguing alternative, as
118                 The incorporation of chicken RCA into NDV produced in embryonated eggs similarly prov
119                         The human complement RCA proteins analyzed were factor H (FH), C4 binding pro
120                             The concatameric RCA product hybridized to biotinylated oligonuclotides w
121 d PDGF-BB was amplified via the concatameric RCA product, and the diffraction gratings on the printed
122                      Under low-N conditions, RCA formation increased rooting depth by 15% to 31%, inc
123                                 In contrast, RCA I injection into TMEV-infected mice induced lesions
124                To define factors controlling RCA generation, adenovirus vectors expressing E2F family
125 (LAD), circumflex (LCX), and right coronary (RCA) territories.
126 alyzed patients with concomitant ULM and CTO-RCA, cardiac-death was significantly higher in patients
127  occlusion of the right coronary artery (CTO-RCA) in patients undergoing percutaneous interventions f
128 rventions and with or without associated CTO-RCA.
129  findings suggest that recanalization of CTO-RCA has significant impact on the long-term cardiac-mort
130 se, 522 had ULM lesions without residual CTO-RCA (493 ULM without CTO-RCA+29 ULM with treated CTO-RCA
131 ess frequently in patients with residual CTO-RCA (adjusted hazard ratios, 0.321 [95% confidence inter
132  as compared with those without residual CTO-RCA (adjusted hazard ratios, 2.163 [95% confidence inter
133 served in patients with ULM and residual CTO-RCA as compared with those without residual CTO-RCA (adj
134 ore frequently in patients with residual CTO-RCA as compared with those without residual CTO-RCA.
135  as compared with those without residual CTO-RCA.
136 d CTO-RCA), and 46 patients had residual CTO-RCA.
137 s with residual as compared with treated CTO-RCA (log-rank P=0.01) despite no difference in baseline
138  ULM without CTO-RCA+29 ULM with treated CTO-RCA), and 46 patients had residual CTO-RCA.
139 ithout residual CTO-RCA (493 ULM without CTO-RCA+29 ULM with treated CTO-RCA), and 46 patients had re
140 ting with a primitive form in cyanobacteria, RCA of chlorophytes evolved by integrating chloroplast t
141  with regular amounts of chlorogenic acid (D-RCA); during the last 6 d of the study, the weight-maint
142 g lipid oxidation increased with C-HCA and D-RCA (P < 0.05).
143 ion of VEGF signaling by AG-028262 decreased RCA I binding and internalization into tumor vessels.
144                      The amplified dendritic RCA detection of DNA is further implemented to yield the
145 analyte sequence, resulting in the dendritic RCA-induced synthesis of the Mg(2+)-dependent DNAzyme un
146 functional hairpin structures, the dendritic RCA-stimulated multiplexed analysis of two different gen
147 mental engineering principles used to design RCA nanotechnologies, discuss recently developed RCA-bas
148 nanotechnologies, discuss recently developed RCA-based diagnostics and bioanalytical tools, and summa
149 ce and then investigated the arousals during RCA.
150 ase in intracoronary ECG ST-elevation during RCA occlusion from baseline to follow-up examination (P=
151                       Angina pectoris during RCA occlusion tended to occur in fewer patients at follo
152 d endogenous testosterone-dependent effects, RCA were obtained from intact males, castrated males, ca
153 expressed recombinant RCA and leaf-extracted RCA, the kinetic properties of the two isoforms were stu
154                                 A 51-feature RCA cytokine glass array was used to measure secretion f
155                                    Following RCA, multiple fluorescently labeled signal probes were h
156 .03, and 0.92 +/- 0.05 vs. 0.75 +/- 0.09 for RCA, P = 0.02).
157  sites in a 200-nm mucin segment to be 4 for RCA, PNA, and UEA, and 1.8 for MALII.
158 4, 1.6, and 26 aJ was determined on pPGM for RCA, PNA, and UEA.
159 robe could in turn be used as a template for RCA.
160 ted, and this circular sequence was used for RCA.
161 ologies are unable to distinguish ricin from RCA 120, a nontoxic protein also found in the castor bea
162                             These functional RCA based nanotechnologies have been utilized for biodet
163 ibody specific for the lytic cycle gammaHV68 RCA protein, but not passive transfer of antibody specif
164                    Deletion of the gammaHV68 RCA protein decreased virulence during acute CNS infecti
165                                The gammaHV68 RCA protein was also important for persistent viral repl
166  the Kaposi's sarcoma-associated herpesvirus RCA homolog Kaposica as a model protein.
167                  The vector with the highest RCA rate also had the least overall sequence identity.
168                                     However, RCA has several limitations.
169       We present crystal structures of human RCA (MCP, DAF, and CR1) and a smallpox virus homolog (SP
170 rcle serves as a template for a novel hybrid RCA strategy that allows for exponential amplification a
171 lification (RAM, also known as hyperbranched RCA) are isothermal nucleic acid amplification technolog
172               Ricinus communis agglutinin I (RCA I), a galactose-binding lectin from castor beans, bi
173 he binding of Ricinus communis agglutinin I (RCA) to sCJD and vCJD samples was significantly increase
174 ty of lectins Ricinus communis agglutinin I (RCA), peanut (Arachis hypogaea) agglutinin (PNA), Maacki
175                                       Immuno-RCA, the specific detection of proteins via antigen-anti
176 ection methods, such as immuno-PCR or immuno-RCA, the bio bar code technique does not employ any enzy
177 aize recombinant inbred lines contrasting in RCA grown under suboptimal and adequate N availability i
178     There were no significant differences in RCA remodeling between genotypes.
179                                 NDV grown in RCA-expressing cells was resistant to complement by inco
180                   Large genetic variation in RCA formation and the utility of RCA for a range of stre
181                           N stress increased RCA formation by 200% in mesocosms and by 90% to 100% in
182 A formation are poorly understood, increased RCA formation appears be a promising breeding target for
183                      These findings indicate RCA I preferentially binds to and is internalized by tum
184                               The individual RCA amplicon molecules were counted on the surface using
185                 After intravenous injection, RCA I bound strongly to tumor vessels but not to normal
186  for coating artificial surfaces with intact RCA are still missing.
187 H shock instead of heat shock and isothermal RCA reaction not only the procedure becomes easier, but
188 he posterior segment of the central isthmus (RCA to inferior vena cava distance).
189 ion of RCA members, particularly CD59 (a key RCA member that controls formation of the membrane attac
190                                     The long RCA product was digested and analyzed by CE.
191 ruck fluctuation test was adapted to measure RCA formation rates.
192                                At 6 minutes, RCA I fluorescence of tumor vessels was largely diffuse,
193 es were compared, only vCJD samples had more RCA binding activity.
194 l amplification (e.g. RPA, HDA, LAMP, NASBA, RCA, ICAN, SMART, SDA).
195                                     This new RCA format demonstrates the practical potential of the n
196 ol mice, infected with TMEV but receiving no RCA I, had inflammatory demyelinating lesions in the ant
197                               The ability of RCA to produce single-stranded DNA tens of thousands of
198 first report to show that direct addition of RCA blockers into plasma from HCV-infected patients rend
199 al enhancement proportional to the amount of RCA product formed.
200 he simplicity and universal applicability of RCA-RCA make it a powerful new tool for genome analysis
201                            Thus, blockage of RCA function represents a novel approach to restore acti
202                   Phylogenetic clustering of RCA sequences suggested that poxvirus complement regulat
203                       Real-time detection of RCA or RAM products has been a challenge because of most
204 ication of HNB for colorimetric detection of RCA reaction further simplifies the assay.
205 wledge of precise structural determinants of RCA proteins critical for imparting the regulatory activ
206 essed this issue by examining the effects of RCA I on blood vessels of spontaneous pancreatic islet-c
207  that blockage of the biological function of RCA members rendered both HIV-1 virions and infected cel
208       Blockage of the biological function of RCA members, particularly CD59 (a key RCA member that co
209 e results illustrate the selective impact of RCA I on VEGF signaling in tumor blood vessels.
210 iologically functional CD59, a key member of RCA.
211 s of this type, a relatively small number of RCA microarrays seem to offer a tractable approach for p
212 argeted recombination and the probability of RCA formation during stock production.
213 ave dissected the structural requirements of RCA proteins that are crucial for one of their two regul
214  in the wild species to thermal stability of RCA, enabling Rubisco to remain active.
215 hat HCV may also use the similar strategy of RCA incorporation to escape ADCML.
216      Although potential fitness tradeoffs of RCA formation are poorly understood, increased RCA forma
217 istributed throughout the dendritic trees of RCA motoneurons, albeit with a strong bias to small-diam
218 ioanalytical tools, and summarize the use of RCA to construct multivalent molecular scaffolds and nan
219                               The utility of RCA also depended on other root phenes and environmental
220 ariation in RCA formation and the utility of RCA for a range of stresses position RCA as an interesti
221                  We evaluated the utility of RCA for N acquisition by physiological comparison of mai
222         On low-nitrate soils, the utility of RCA formation was 56% greater in coarser soils with high
223                       The greater utility of RCA on low-potassium soils is associated with the fact t
224 w-phosphorus soils (7.5 muM), the utility of RCA was 2.9 times greater in plants with increased later
225                        Diagnostic utility of RCA-amplified protein chips has been shown for multiplex
226    The effect of obesity (BMI>30 kg/m(2)) on RCA raised lesions was greater in young men with a thick
227 transgene cassette had the largest effect on RCA rate.
228 of side branches is lower than in the LAD or RCA and there are no septal perforators with intramuscul
229 al relationships among SCRs of orthopoxvirus RCA-like proteins and those of human complement regulato
230 oise ratio was also measured on the in-plane RCA images.
231                      The combination of PNA, RCA, and DNAzymes allows for sequence-specific and highl
232 lity of RCA for a range of stresses position RCA as an interesting crop-breeding target for enhanced
233  and/or transcription direction as potential RCA rate modifiers.
234  a new whole genome amplification procedure, RCA-RCA (Restriction and Circularization-Aided Rolling C
235 ction efficiency and simplify the procedure, RCA was not preceded with ligation, and a preformed circ
236 efined: proximal right coronary artery (prox RCA), mid and distal left anterior descending artery and
237 rnal mammary chain (IMC), high risk for prox RCA and mdLAD + dD from 1970 to 1995 and thereafter sole
238 dLAD + dD; and right IMC, high risk for prox RCA.
239                                     Proximal RCA occlusion compromising RV branch perfusion commonly
240 pidemia, and smoking contributed to proximal RCA thickening, independent of atherosclerotic plaque qu
241                  In some cases with proximal RCA culprits, collaterals or spontaneous reperfusion pre
242             Other control mice that received RCA I alone did not develop inflammatory lesions.
243                  Using expressed recombinant RCA and leaf-extracted RCA, the kinetic properties of th
244 ndogenous testosterone by castration reduced RCA PKCdelta protein levels, an effect partially (approx
245 cificity for ricin versus the highly related RCA 120 (1 to 10 000).
246 ibody that enhanced the activities of ricin, RCA, and abrin II to different extents, thus improving t
247 re oligonucleotides and amplified by a short RCA.
248                              Moreover, since RCA products can be tailor-designed by manipulating the
249  labeling method in combination with surface RCA as reporter system to achieve both high sequence spe
250             Two un-silanized glass surfaces, RCA-cleaned and immersed in Tris-EDTA buffer were also s
251 igned by manipulating the circular template, RCA has been employed to generate complex DNA nanostruct
252                             We conclude that RCA can serve as a reliable method to replicate complex
253                    Here, we demonstrate that RCA using random hexamer primers with 29 DNA polymerase
254    These results provide clear evidence that RCA is a major limiting factor in plant photosynthesis u
255 quantitative support for the hypothesis that RCA formation is a useful adaptation to suboptimal avail
256 ults are consistent with the hypothesis that RCA improves plant growth under N-limiting conditions by
257               Based on previous reports that RCA is heat-labile, the Rubisco activation state was mea
258        Microsatellite analysis revealed that RCA-RCA amplified genomic DNA is representative of the o
259                Previous research showed that RCA formation reduces the respiration and nutrient conte
260                                          The RCA fluctuation test should be useful for investigators
261                                          The RCA genome contains E1 DNA acquired from the 293 cellula
262                                          The RCA product is a concatemer containing tens to hundreds
263                                          The RCA-produced long, single-stranded DNA with repeating un
264                    The analyte activates the RCA process, leading to DNA chains consisting of the Mg(
265 eobacter DC5-80-3 cluster (also known as the RCA clade) is among the most abundant bacterial lineages
266                  The AVN was supplied by the RCA in 89 patients, the LCX artery in 11 patients, and b
267 RCA) to the inferior vena cava, and from the RCA to the tricuspid valve annulus were measured.
268                             Furthermore, the RCA binding activity in sCJD and vCJD samples is mostly
269 cular function expressed as lower Ecc in the RCA (P<0.01) and left circumflex regions (P<0.05) measur
270 lysis revealed numerous polymorphisms in the RCA amino acid sequence from O. australiensis.
271 er within the proximal segment, while in the RCA their distribution is more uniform.
272                 Therefore, while most of the RCA binding activity in sCJD is restricted to the full-l
273 ng notion that CD46 and other members of the RCA family are co-opted in distinct manners by different
274 RCA) of repeats in vitro and assembly of the RCA products by in vivo recombination in yeast.
275 alize the single-stranded DNA product of the RCA reaction labeled with the fluorescent dye SYBR Green
276                 In patients without RVI, the RCA was the culprit in 89%; the circumflex, in 11%.
277 stricted to the full-length PrP species, the RCA binding activity in vCJD is associated with truncate
278 ernate splicing mechanism, which splices the RCA-alpha and RCA-beta isoforms were probably gained fro
279  RVI occurred in 53 (42%) patients, with the RCA as the culprit vessel and the lesion sufficiently pr
280 anded loop domain that communicates with the RCA product.
281     To test the hypothesis that thermostable RCA can improve photosynthesis under elevated temperatur
282 ) were independently associated with thicker RCA vessel walls.
283 g the structure-switching aptamer, real-time RCA can be used to specifically quantitate PDGF down to
284           The aptamer can also be adapted to RCA on surfaces, although quantitation proved to be more
285  shown here that an excellent alternative to RCA labeling is tagging with gold nanoparticles followed
286 nal narrowing, and plaque was not related to RCA wall thickness.
287                               Traditionally, RCA has been used to develop sensitive diagnostic method
288 v, and provide a framework for understanding RCA disease-related mutations and immune evasion.
289       Collateral flow index in the untreated RCA and left coronary artery changed from 0.071+/-0.082
290             When intact genomic DNA is used, RCA-RCA retains gene-amplification differences (twofold
291                                        Using RCA, we identified two distinct subtypes of cancer-assoc
292                                        Using RCA-RCA, formalin-fixed samples of modest or substantial
293  both protein and DNA in a single test using RCA, the limit of detection for IL-8 and IL-6 was improv
294                        Empty cassette vector RCA rates ranged from 2.5 x 10(-8) to 5.6 x 10(-10).
295 mpared to their corresponding empty vectors, RCA rates were not increased but were slightly decreased
296 ll as those within specific target genes via RCA-based enrichment.
297 cation of cDNA is successfully performed via RCA-RCA and results to unbiased gene expression analysis
298  stable up to 42 degrees C, contrasting with RCA from O. sativa, which was inhibited at 36 degrees C.
299 rs (P < .01) were positively correlated with RCA wall thickness.
300  A or B chains and low cross-reactivity with RCA 120.
301 a combination of antiretroviral therapy with RCA blockage, provirus activators, and therapeutic vacci

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