ライフサイエンスコーパス: RDE

1 RDE experiments often make use of or require collection

2 RDE studies indicate that inhibition by cocaine, specifi

3 RDE-12 colocalizes with WAGO-1 in germline P granules an

4 RDE-3 contains conserved domains found in the polymerase

5 RDE-4 preferentially binds long dsRNA, while TRBP binds

6 RDE-4 protein also interacts in vivo with DCR-1, RDE-1,

7 RDE-8 can cleave RNA in vitro and is needed for the prod

8 with peak current density of 16,000 A g(-1) (RDE) and 450 mW cm(-2) operated in air (MEA).

9 4 protein also interacts in vivo with DCR-1, RDE-1, and a conserved DExH-box helicase.

10 Genetic analysis indicates that the RDE-10/RDE-11 complex acts in parallel to nuclear RNAi.

11 The RDE-10/RDE-11 complex and the RNA-dependent RNA polymerase RRF-

12 Therefore, the RDE-10/RDE-11 complex is critical for amplifying the exogenous

13 The RDE-10/RDE-11 complex is essential for the amplification of RNA

14 cal approaches, we report a divergent RDE-10/RDE-11 complex that is required for RNAi in C. elegans.

15 ns suggest that ABC(RNAi) proteins and MUT-7/RDE-2 function together in parallel pathways and/or as m

16 E protein possesses sialate-O-acetylesterase RDE activity.

17 s the corresponding sialate-O-acetylesterase RDE activity.

18 tion of the PtNi nanoparticle catalyst after RDE testing revealed the development of hollows in a num

19 t recruited to target mRNA by upstream AGOs (RDE-1 and ERGO-1), where it promotes small RNA amplifica

20 However, the conductance (G) measured by an RDE depends on the depth (D) of the liquid below the pro

21 erited silencing is independent of SID-1 and RDE-1, but requires HRDE-1 and MUT-7.

22 findings suggest a model in which RDE-4 and RDE-1 function together to detect and retain foreign dsR

23 the ability of RDE-4 deletion constructs and RDE-4/TRBP chimeras to reconstitute Dicer activity sugge

24 llective actions of both RDE-4-dependent and RDE-4-independent mechanisms to produce RNAi-inducing vi

25 ouble-stranded RNA is processed by Dicer and RDE-1/Argonaute into primary siRNA that guides target mR

26 germline requires SID-1, a primary Argonaute RDE-1, a secondary Argonaute HRDE-1, and an RNase D homo

27 enzymatic activity of the primary Argonaute, RDE-1, is not required for silencing activity.

28 the dsRNA importer, SID-1 and the argonaute, RDE-1.

29 enous GlyR agonists (glycine, taurine) block RDE by preventing the closure of postsynaptic GlyRs.

30 ns depends on the collective actions of both RDE-4-dependent and RDE-4-independent mechanisms to prod

31 By RDE we mean modifying the emission of fluorophores or ch

32 We found that a component of Dicer complex RDE-4 and a chromatin-related zinc finger protein ZFP-1,

33 iochemical approaches, we report a divergent RDE-10/RDE-11 complex that is required for RNAi in C. el

34 During RDE, GlyRs are less responsive to local glycine applicat

35 s (unilateral cover testing, Random Dot "E" [RDE] and Stereo Smile Test II [Stereo Optical, Inc., Chi

36 this phenomenon as rate-dependent efficacy (RDE).

37 erials show in both rotating disc electrode (RDE) and membrane electrode assembly (MEA) tests the wor

38 y was detected with rotating disk electrode (RDE) amperometry and an interdigitated array (IDA) elect

39 onoamperometric and rotating disk electrode (RDE) data.

40 Rotating disk electrode (RDE) experiments were carried out to study the catalytic

41 onoamperometry, and rotating disk electrode (RDE) experiments.

42 ned using classical rotating disk electrode (RDE) experiments.

43 was coupled to a Au rotating disk electrode (RDE) for monitoring at near-normal incidence the reflect

44 dip-type small diameter ring-disk electrode (RDE) is ideal for very small volumes.

45 GOae) modified on a rotating disk electrode (RDE) is presented.

46 ere measured with a rotating disk electrode (RDE) technique.

47 further examined in rotating disk electrode (RDE) tests that minimized mass transfer limitations.

48 atinum catalysts in rotating disk electrode (RDE) tests.

49 -Levich model for a rotating disk electrode (RDE) to a general heterogeneous electrochemical kinetic

50 the ss-HSDNA/rGOae rotating disk electrode (RDE) toward AFB1 detection using FcCH2OH as the redox me

51 at the surface of a rotating disk electrode (RDE) used to measure chemical fluxes.

52 In vitro rotating disk electrode (RDE) voltammetry and in vivo microdialysis were used to

53 Rotating disk electrode (RDE) voltammetry at glassy carbon electrodes in 300- to

54 Rotating disk electrode (RDE) voltammetry is applied to the measurement of the tr

55 Caenorhabditis elegans RDE-4 facilitates cleavage of long dsRNA to small interf

56 leading to loss of repression of endogenous RDE-1 targets.

57 E-1 can instead recruit an endoribonuclease, RDE-8, to target RNA.

58 n fluorescence, radiative decay engineering (RDE).

59 , and acted as a receptor-destroying enzyme (RDE) capable of eliminating the binding of HKU1-S1 to RD

60 se and acts as a receptor-destroying enzyme (RDE) for hCoV-HKU1.

61 Downstream of these events, RDE-12 forms an RNase-resistant (target mRNA-independent

62 otein complex containing the new RNAi factor RDE-11, the known RNAi factors RSD-2 and ERGO-1, and oth

63 which are also regulated by the RNAi factor RDE-3.

64 Furthermore, RDE-11 is required for mRNA degradation subsequent to ta

65 on black supported catalyst mixtures on a GC RDE and the electrocatalytic activity determined using t

66 We also describe how RDE can be applied to medical testing and biotechnology.

67 with an edgeless feature, and a custom-made RDE/RRDE working station was designed to provide unique

68 ata obtained using more typical, nongastight RDE cells.

69 naptic GlyRs under all conditions, occluding RDE.

70 Additionally, analyses of the ability of RDE-4 deletion constructs and RDE-4/TRBP chimeras to rec

71 because DEPS-1 promotes the accumulation of RDE-4, a dsRNA-binding protein required for RNAi.

72 ed rde-10, and through proteomic analysis of RDE-10-interacting proteins, we identified a protein com

73 rts and gaseous analytes makes the design of RDE cells that allow for headspace analysis challenging

74 ynthesis by orchestrating the recruitment of RDE-10 and RRF-1 to primary siRNA-targeted mRNA in disti

75 and suggest possible models for the role of RDE-3 in the RNAi mechanism.

76 ther, these findings document the utility of RDE for the nonisotopic measurement of neurotransmitter

77 the complex with target mRNA is dependent on RDE-1 but not RRF-1, suggesting that target mRNA recogni

78 virus, which redirects the Argonaute protein RDE-1 from its endogenous small RNA cofactors, leading t

79 he RdRP RRF-3, and the dsRNA-binding protein RDE-4 are required for the biogenesis of 26-nt small RNA

80 tis elegans, where the dsRNA-binding protein RDE-4 initiates silencing by recruiting an endonuclease

81 hich partners with the dsRNA binding protein RDE-4 to process dsRNA into viral siRNAs (viRNAs).

82 1 and the secondary siRNA biogenesis protein RDE-2.

83 an interactor of the RNAi-defective protein RDE-10, and ntl-9/CNOT9, one of several CCR4/NOT complex

84 and a conserved Vasa ATPase-related protein RDE-12.

85 s to the Caenorhabditis elegans RNAi protein RDE-4.

86 ers potent antiviral silencing that requires RDE-1, an Argonaute protein essential for RNAi mediated

87 Overall, a 3.7 +/- 1.4 nm diameter PdNPs/rGO RDE exhibits high performance with a rather low limit of

88 ly ignored, and the 3.7 +/- 1.4 nm PdNPs/rGO RDE may be useful toward trace hydrazine detection, espe

89 meras to reconstitute Dicer activity suggest RDE-4 promotes activity using its dsRNA-binding motif 2

90 s are mechanistically based on the fact that RDE-4 binds cooperatively, via contributions from multip

91 We also find that RDE-8 promotes RdRP activity, thereby ensuring amplifica

92 We report that RDE-12, a conserved phenylalanine-glycine (FG) domain-co

93 We show that RDE-1 can instead recruit an endoribonuclease, RDE-8, to

94 We show that RDE-1 interacts with trigger-derived sense and antisense

95 indings and our genetic studies suggest that RDE-12 is first recruited to target mRNA by upstream AGO

96 Our results suggest that RDE-12 promotes secondary siRNA synthesis by orchestrati

97 This result suggests that RDE contributes to long-term synaptic plasticity in the

98 The RDE kinetically resolves transmembrane transport with a

99 The RDE method also allows observation of outward transport

100 The RDE tests showed that the limiting current of the AC wit

101 The RDE was found to be able to measure dopamine and its met

102 The RDE-10/RDE-11 complex and the RNA-dependent RNA polymera

103 The RDE-10/RDE-11 complex is essential for the amplification

104 Within a solution stirred by the RDE, both diffusion and hydrodynamic boundary layers are

105 By extending the RDE induction protocol to include 500 paired presynaptic

106 Calibration of the RDE using a tachometer shows that the rotation speed of

107 Genetic analysis indicates that the RDE-10/RDE-11 complex acts in parallel to nuclear RNAi.

108 Therefore, the RDE-10/RDE-11 complex is critical for amplifying the exo

109 ide a spreadsheet-based calculator where the RDE dimensions are the input parameters and the procedur

110 f GlyRs, either pharmacologically or through RDE, also lead to increased LTD.

111 itivity of membrane-inserted GlyRs underlies RDE.

112 Our findings suggest a model in which RDE-4 and RDE-1 function together to detect and retain f

113 ether, our findings suggest a model in which RDE-8 cleaves target mRNAs to mediate silencing, while g

114 f other mRNAs, perhaps by collaborating with RDE-3 to generate endogenous short interfering RNAs (end

115 MS2 or 3.2 x 10(10) viral particles/mL with RDE amperometry.