ライフサイエンスコーパス: RNA polymerase

1 is with an efficacy similar to inhibition of RNA polymerase.

2 s, YonO is a highly processive DNA-dependent RNA polymerase.

3 rase I for protein-protein interactions with RNA polymerase.

4 n of nsp14 with the low-fidelity nsp12 viral RNA polymerase.

5 poI-CTD are involved in the interaction with RNA polymerase.

6 ed sigma subunits of plastid-encoded plastid RNA polymerase.

7 nonical rifampin target, the beta subunit of RNA polymerase.

8 as a secondary function of an RNA-dependent RNA polymerase.

9 ion, the methyltransferase and RNA-dependent RNA polymerase.

10 action between bacterial topoisomerase I and RNA polymerase.

11 rtially reflects an interaction of Top1 with RNA polymerase.

12 end is responsible for the interaction with RNA polymerase.

13 -induced nucleosome intermediates using only RNA Polymerase.

14 s II fructose bisphosphate aldolase, but not RNA polymerase.

15 rimental measurements of the distribution of RNA polymerases.

16 vity and fidelity of archaeal and eukaryotic RNA polymerases.

17 ut remarkably similar to viral RNA-dependent RNA polymerases.

18 d ability of PcrA/UvrD to bind and backtrack RNA polymerase (1,2) might be relevant to these function

19 ated transactivation by phosphorylating both RNA polymerase 2 complex proteins and AR at S81.

20 h the Integrator complex, which functions in RNA polymerase 2 pause release.

21 We found that transcription initiation by RNA polymerase 2 resulted in confinement of the mRNA-pro

22 localize at gene promoters containing paused RNA polymerase 2, and Integrator similarly regulates neu

23 ke etnangien, gladiolin was found to inhibit RNA polymerase, a validated drug target in M. tuberculos

24 e wide and profile the enzymatic activity of RNA polymerase across various loci and following experim

25 We finish with a systematic comparison of RNA Polymerase activity at promoter versus non-promoter

26 RNA polymerase activity is regulated by nascent RNA sequ

27 h source of information on the regulation of RNA polymerase activity.

28 tein expression 5- to 10-fold compared to T7 RNA polymerase alone while enhancing reovirus rescue fro

29 sing enzymes, including a DNA polymerase, an RNA polymerase and a DNA ligase, to use Fe2+ in place of

30 Left unchecked, this causes titration of RNA polymerase and a global downshift in host gene expre

31 r named sigma(S) (RpoS) that associates with RNA polymerase and controls the expression of numerous g

32 GreA restarts backtracked RNA polymerase and hence promotes transcription fidelity

33 itional detection of the viral DNA-dependent RNA polymerase and intermediate and late transcription f

34 C3P3, a fusion protein containing T7 RNA polymerase and NP868R, was found to increase protein

35 The interactions between RNA polymerase and ribosomes are crucial for the coordin

36 In prokaryotes, RNA polymerase and ribosomes can bind concurrently to th

37 RNA polymerase and ribosomes form a one-to-one complex w

38 This direct interaction between RNA polymerase and ribosomes may contribute to the coupl

39 the conformational and functional states of RNA polymerase and the ribosome.

40 ts of RNAs produced by different chloroplast RNA polymerases and differs from the pattern of RNA foun

41 nal pausing and lead to conflicts with other RNA polymerases and replication in bacteria and eukaryot

42 ation of SeqKernel to inferring phylogeny on RNA polymerases and show that it performs as well as met

43 -coil is a docking site for sigma factors on RNA polymerase, and evidence is presented that the bindi

44 sigma factor to prevent its association with RNA polymerase, and instead functions to inhibit sigma(F

45 2, which associates with the plastid-encoded RNA polymerase, and is essential for inducing the plasto

46 upancy TP53 enhancers, high levels of paused RNA polymerases, and accessible chromatin.

47 Our findings suggest that increased RNA polymerase backtracking promotes break repair by ins

48 The PB2 subunit of the viral heterotrimeric RNA polymerase binds the cap structure of cellular pre-m

49 DTPs were thought to target RNA polymerase, but conflicting observations leave the m

50 Acquisition of alternative RNA polymerases by recombination is an important mechani

51 The idea that backtracked RNA polymerase can stimulate recombination presents a DN

52 CO2 Unlike the photosynthetic complexes, the RNA polymerase complex and ribosomes were produced in hi

53 we present the structure of Escherichia coli RNA polymerase complexed with NusG.

54 of PcrA/UvrD to interact with and to remodel RNA polymerase complexes in vitro.

55 ed and replicated by the viral RNA-dependent RNA polymerase, composed of the subunits PA, PB1, and PB

56 ge also becomes less pronounced upon reduced RNA polymerase concentration.

57 roneously generated by slippage of the viral RNA polymerase confer a translational advantage.

58 Influenza virus RNA-dependent RNA polymerase consists of three viral protein subunits:

59 keeps the nascent transcription rates of its RNA polymerases constant and increases mRNA stability.

60 ion of the nonessential omega-subunit of the RNA polymerase core in the DeltarpoZ strain of the model

61 Here, we report that RNA polymerase directly binds ribosomes and isolated lar

62 Based on its crystal structure, the RNA polymerase domain contains two Mg(II) ions.

63 at recognizes a specific DNA sequence and an RNA polymerase domain that catalyzes RNA polymerization.

64 tein interaction between topoisomerase I and RNA polymerase during stress response of mycobacteria.

65 rface regions that could potentially prevent RNA polymerase from docking to the ribosome.Under condit

66 is domain has been shown to be essential for RNA polymerase function.

67 tified adaptive point mutations in the viral RNA polymerase gene A24R and, surprisingly, found that o

68 tinct mutations were identified in the viral RNA polymerase gene A24R, which seem to act through diff

69 hat measure the location of actively engaged RNA polymerase genome wide.

70 genes (TCOF1, POLR1C and POLR1D) involved in RNA polymerase I (Pol I) transcription account for more

71 tudy reveals that the selective inhibitor of RNA polymerase I (Pol I) transcription, CX-5461, effecti

72 R-loops accumulate in nucleoli during RNA polymerase I (RNAP I) transcription.

73 how that nucleolar SmgGDS interacts with the RNA polymerase I transcription factor upstream binding f

74 NuMA coimmunoprecipitates with RNA polymerase I, with ribosomal proteins RPL26 and RPL2

75 f the polymerase I and SL1 complexes and the RNA polymerase I-specific transcription initiation facto

76 out 0.5 microM CX-5461 (CX), an inhibitor of RNA polymerase I.

77 Here we employ a set of RNA Polymerase II (Pol II) activity mutants to determine

78 Phosphorylation of the RNA polymerase II (Pol II) C-terminal domain (CTD) regul

79 te the degradation of Rpb1, a subunit of the RNA polymerase II (Pol II) complex, and therefore hamper

80 n (ChIP) and chemical inhibitor studies that RNA polymerase II (Pol II) elongation is important for e

81 facilitate ubiquitylation and degradation of RNA polymerase II (pol II) in response to multiple stimu

82 Transcription by RNA polymerase II (Pol II) is dictated in part by core p

83 Elongation of RNA polymerase II (Pol II) is thought to be an important

84 The carboxy-terminal domain (CTD) of the RNA polymerase II (Pol II) large subunit cycles through

85 minal domain (CTD) of the largest subunit of RNA polymerase II (Pol II) orchestrates dynamic recruitm

86 RNA polymerase II (Pol II) pauses downstream of the tran

87 on P-TEFb recruitment and the regulation of RNA polymerase II (Pol II) pausing.

88 Gene expression in metazoans is regulated by RNA polymerase II (Pol II) promoter-proximal pausing and

89 While the nucleosome positioning at RNA polymerase II (pol II) promoters has been extensivel

90 Active NL genes with higher RNA polymerase II (Pol II) recruitment levels tend to di

91 iption is regulated at many steps, including RNA polymerase II (Pol II) recruitment, transcription in

92 tory step in gene expression, which requires RNA polymerase II (pol II) to escape promoter proximal p

93 In eukaryotes, RNA polymerase II (pol II) transcribes all protein-codin

94 The RNA polymerase II (Pol II) transcription elongation fact

95 Termination of RNA polymerase II (Pol II) transcription is an important

96 tisense RNAs are a mechanistic by-product of RNA polymerase II (Pol II) transcription or biologically

97 ) are generated from the mammalian genome by RNA polymerase II (Pol II) transcription.

98 find that 6mA is exclusively associated with RNA polymerase II (Pol II)-transcribed genes, but is not

99 template strand that block translocation of RNA polymerase II (Pol II).

100 cent transcripts in promoter-proximal paused RNA polymerase II (Pol II).

101 RNA polymerase II (Pol2) movement through chromatin and

102 A unique feature of RNA polymerase II (RNA pol II) is its long C-terminal ex

103 (ChIP) studies illustrated that M inhibited RNA polymerase II (RNAP II) recruitment to gene promoter

104 ssociated with genes actively transcribed by RNA polymerase II (RNAPII) and is catalyzed by Saccharom

105 nt and the accumulation of P-TEFb-associated RNA polymerase II (RNAPII) C-terminal domain (CTD)-Ser7

106 nitiation and regulation of transcription by RNA polymerase II (RNAPII) in eukaryotes rely on the tra

107 transcript elongation of subsets of genes by RNA polymerase II (RNAPII) in the chromatin context.

108 Release of promoter-proximally paused RNA polymerase II (RNAPII) is a recently recognized tran

109 RNA polymerase II (RNAPII) passes through the nucleosome

110 Given that the elongating RNA polymerase II (RNAPII) stalls at this well positione

111 7, regulates the mRNA elongation capacity of RNA polymerase II (RNAPII) through controlling the nucle

112 e coding strand of genes block elongation by RNA polymerase II (RNAPII).

113 vealed that nucleosomes impede elongation of RNA polymerase II (RNAPII).

114 t of PRC-bound genes actively transcribed by RNA polymerase II (RNAPII).

115 feration and migration, and to interact with RNA Polymerase II (RNAPII).

116 ortem brain, and pharmacologic modulation of RNA polymerase II activity altered repetitive element ex

117 We conclude that increased RNA polymerase II activity in ALS/FTLD may lead to incre

118 lement expression positively correlated with RNA polymerase II activity in postmortem brain, and phar

119 einitiation complex (PIC), which consists of RNA polymerase II and general transcription factors.

120 TFIID binds promoter DNA to recruit RNA polymerase II and other basal factors for transcript

121 ides, and coincide spatially with elongating RNA polymerase II and splicing components.

122 ntified transcriptome-wide binding sites for RNA polymerase II and the exosome cofactors Mtr4 (TRAMP

123 ive viral transcription by focal assembly of RNA polymerase II around Kaposi's sarcoma-associated her

124 In absence of HBV replication, RNA polymerase II associated with SALL4 exon1.

125 suppressed the initiation and elongation of RNA polymerase II at active genes genome-wide, with pron

126 mine the first room-temperature structure of RNA polymerase II at high resolution, revealing new stru

127 gatively impacts levels of promoter-proximal RNA polymerase II at protein-coding (pc) genes.

128 In metazoans, the pausing of RNA polymerase II at the promoter (paused Pol II) has em

129 al factories" decreased the pool of cellular RNA polymerase II available for cellular gene transcript

130 In addition, through its interaction with RNA Polymerase II C-terminal domain (CTD) and affecting

131 on elongation through phosphorylation of the RNA polymerase II C-terminal domain.

132 of higher-order chromatin structure data and RNA polymerase II ChIA-PET data from MCF-7 cells did not

133 RNA polymerase II contains a long C-terminal domain (CTD

134 RNA polymerase II contains a repetitive, intrinsically d

135 denylation factor SYDN-1, which inhibits the RNA polymerase II CTD phosphatase SSUP-72.

136 ive elongation factor (NELF) associates with RNA polymerase II during early elongation and causes RNA

137 troller for transcription activation through RNA polymerase II elongation at a subset of genomic piRN

138 Moreover, we demonstrate that altering the RNA polymerase II elongation rate in either direction co

139 RNA synthesis, transcription initiation and RNA polymerase II elongation.

140 Processive elongation of RNA Polymerase II from a proximal promoter paused state

141 n cryo-electron microscopy map of a Mediator-RNA polymerase II holoenzyme reveals that changes in the

142 scernable decrease in the elongating form of RNA polymerase II in either mutant.

143 g signals from transcriptional regulators to RNA polymerase II in eukaryotes.

144 The release of paused RNA polymerase II into productive elongation is highly r

145 matin occupancy of serine 2-unphosphorylated RNA polymerase II is increased, and that of topoisomeras

146 finding revealed that the exosomes increase RNA polymerase II loading onto the HIV-1 promoter in the

147 OUP-TFII was regulated by ensuring efficient RNA polymerase II machinery binding.

148 d kinetics of post-translational histone and RNA polymerase II modifications.

149 OCSs correlate with RNA polymerase II occupancy and active chromatin marks,

150 tome profiling, chromatin accessibility, and RNA polymerase II occupancy demonstrate that BTBD18 faci

151 By contrast, in HBV replicating cells RNA polymerase II occupancy of all SALL4 exons increased

152 chromatin immunoprecipitation (ChIP) assays RNA polymerase II occupancy of SALL4 gene, as a function

153 n be activated by decreasing the duration of RNA polymerase II pausing in the promoter-proximal regio

154 ion factors EBF1, EGR1 or MEF2C depending on RNA Polymerase II pausing.

155 acterium ND2006 (Lb) in plants, using a dual RNA polymerase II promoter expression system.

156 sses such as transcription factor occupancy, RNA polymerase II recruitment and initiation, nascent tr

157 pho-p65 or phospho-CREB and CBP bindings and RNA polymerase II recruitment to these promoters in mesa

158 ecome enriched at RA target genes to promote RNA polymerase II recruitment.

159 Fusing Set1 to RNA polymerase II results in H3K4me2 throughout transcri

160 e beta-tubulin (BenA), calmodulin (CaM), and RNA polymerase II second largest subunit (RPB2) genes.

161 increased binding of total and phospho-Ser2 RNA polymerase II specifically at the intron retained un

162 revisiae Spt6 binds the linker region of the RNA polymerase II subunit Rpb1 rather than the expected

163 Upon inhibiting RNA polymerase II termination via depletion of the cleav

164 y decreased recruitment of NF-kappaB p65 and RNA polymerase II to COX-2 and IL-8 promoters.

165 based mutagenesis reduced the recruitment of RNA polymerase II to ENL-target genes, leading to the su

166 tion of DNA replication per se or loading of RNA polymerase II to late promoters and subsequent reduc

167 merase II during early elongation and causes RNA polymerase II to pause in the promoter-proximal regi

168 in reduced binding of actively transcribing RNA polymerase II to the endogenous Asc gene, resulting

169 eneral cofactor required for essentially all RNA polymerase II transcription and is not consistent wi

170 The human Mediator complex regulates RNA polymerase II transcription genome-wide.

171 x has an essential role in the regulation of RNA polymerase II transcription in all eukaryotes.

172 d TFIID are alternative factors that promote RNA polymerase II transcription, with about 10% of genes

173 ve genes and disrupted recruitment of active RNA polymerase II, a property shared with pan-BETis that

174 to form mediator complexes, phosphorylating RNA polymerase II, and by its intrinsic histone acetyltr

175 that both enhancer classes are enriched for RNA Polymerase II, CBP, and architectural proteins but t

176 bed with 12 pure proteins (80 polypeptides): RNA polymerase II, six general transcription factors, TF

177 assembly of large protein complexes, such as RNA polymerase II, small nucleolar ribonucleoproteins an

178 plexes and recruit coactivator complexes and RNA polymerase II, thereby inducing transcription.

179 function of VIP proteins, components of the RNA polymerase II-associated factor 1 complex (Paf1c).

180 or the regulated transcription of nearly all RNA polymerase II-dependent genes.

181 with PC4 and cofilin, which are involved in RNA polymerase II-dependent transcription.

182 and in the transcription of coding genes by RNA polymerase II.

183 o the expression of all genes transcribed by RNA polymerase II.

184 minal domain (CTD) of the largest subunit of RNA polymerase II.

185 associate with the core mediator complex of RNA polymerase II.

186 ike domain (PLD) to the C-terminal domain of RNA polymerase II.

187 recruited a significant fraction of cellular RNA polymerase II.

188 ted with Set1 (COMPASS) to promoter-proximal RNA polymerase II.

189 or (Inr), direct transcription initiation by RNA polymerase II.

190 regulatory element for genes transcribed by RNA polymerase II.

191 ex, which regulates transcription pausing of RNA-polymerase II.

192 exit of MKL, and sequestration of p65 at the RNA-polymerase-II foci.

193 Our data also revealed that RNA-polymerase-II-associated proteins like PAF1 and RTF1

194 BocaSR is transcribed by RNA polymerase III (Pol III) from an intragenic promoter

195 RNA polymerase III (Pol III) transcribes medium-sized no

196 is a class of retrotransposon transcribed by RNA polymerase III (Pol III).

197 RNA polymerase III (RNAPIII) components, including Rpc53

198 tRNAs, and other transcripts synthesized by RNA polymerase III and facilitates their maturation, whi

199 positive-sense genome and is transcribed by RNA polymerase III into a noncoding RNA of 140 nt.

200 mutations as gRNAs expressed from individual RNA polymerase III promoters.

201 osons evolutionarily derived from endogenous RNA Polymerase III RNAs.

202 We selected the BRF1 gene, which encodes an RNA polymerase III transcription initiation factor subun

203 of retrotransposons that are transcribed by RNA polymerase III, thus generating exclusively noncodin

204 of polyglutamine, MOAG-2/LIR-3 regulates the RNA polymerase III-associated transcription of small non

205 ncing, SINE-seq), which selectively profiles RNA Polymerase III-derived SINE RNA, thereby identifying

206 t ER was associated with a large fraction of RNA polymerase III-transcribed tRNA genes, independent o

207 ental single-molecule tracking (SMT) data of RNA polymerase in live Escherichia coli cells.

208 m of interaction between topoisomerase I and RNA polymerase in Mycobacterium tuberculosis and Mycobac

209 s are transcribed by the viral RNA-dependent RNA polymerase in the cell nucleus before being exported

210 t can be recapitulated by RNase treatment or RNA polymerase inhibition - and cause defects in heteroc

211 le the paralogous TFS4 evolved into a potent RNA polymerase inhibitor.

212 may be a frequent by-product of promiscuous RNA polymerase initiation at accessible chromatin and is

213 s a Tudor-like fold that is similar to other RNA polymerase interaction domains, including that of th

214 that the release of promoter-proximal paused RNA polymerase into elongation functions as a critical s

215 Bacterial RNA polymerase is able to initiate transcription with ad

216 nted that the binding of Fin and sigma(F) to RNA polymerase is mutually exclusive.

217 at the PB2 627 domain of the influenza virus RNA polymerase is not involved in core catalytic functio

218 inhibits a subset of metalloenzymes and that RNA polymerase is unlikely to be the primary target.

219 ost het-siRNAs depends on the plant-specific RNA polymerase IV (Pol IV), and ARGONAUTE4 (AGO4) is a m

220 lutinin-neuraminidase (HN) and RNA-dependent RNA polymerase (L) genes of the PIV5 genome [PIV5-RSV-F

221 P) is the main and essential cofactor of the RNA polymerase (L) of non-segmented, negative-strand RNA

222 rus 1) with a highly divergent RNA-dependent RNA polymerase missed by conventional BLAST searches, an

223 6 x 10(-6)), and human mitochondrial POLRMT (RNA polymerase mitochondrial) (2 x 10(-5)) indicate high

224 Experimentally, we could detect small viral RNA polymerase molecules, distributed randomly among bin

225 g organisms is accomplished by multi-subunit RNA polymerases (msRNAPs).

226 driven by a single-subunit, factor-dependent RNA polymerase (mtRNAP).

227 anscriptome-wide epimutations resulting from RNA polymerase mutants and oxidative stress.

228 rase I (TopoI-CTDs) and the beta' subunit of RNA polymerase of M. smegmatis in the absence of DNA.

229 erring steric hindrance on the RNA-dependent RNA polymerases of diverse positive-stranded RNA viruses

230 dentified 12 primary miRNAs with significant RNA polymerase pausing alterations after JQ1 treatment;

231 The activity of plastid-encoded RNA polymerase (PEP) and the expression of genes partici

232 ive histone mark H3K9me2 and by reduction in RNA polymerase Pol II occupancy.

233 r profile suggesting their capacity to stall RNA polymerase (Pol) II and trigger transcription-couple

234 For transcription through chromatin, RNA polymerase (Pol) II associates with elongation facto

235 phospho-Ser 2 carboxy-terminal domain (CTD) RNA polymerase (Pol) II formation on the promoters of IR

236 MAF1 is a conserved negative regulator of RNA polymerase (pol) III and intracellular lipid homeost

237 Initiation of gene transcription by RNA polymerase (Pol) III requires the activity of TFIIIB

238 rkable in having two additional multisubunit RNA polymerases, Pol IV and Pol V, which synthesize nonc

239 ry in humans consists of three proteins: the RNA polymerase (POLRMT) and two accessory factors, trans

240 G is to enhance transcription elongation and RNA polymerase processivity.

241 Rifampicin, which inhibits bacterial RNA polymerase, provides one of the most effective treat

242 n Nicotiana attenuata, specific RNA-directed RNA polymerase (RdR1) and the Dicer-like (DCL3 and DCL4)

243 and-mouth disease virus (FMDV) RNA-dependent RNA polymerase (RdRp) (3D(pol)) catalyzes viral RNA synt

244 ication of the viral siRNAs by RNA-dependent RNA polymerase (RdRP) 1 (RDR1) and RDR6 and of the endog

245 poration fidelity of the viral RNA-dependent RNA polymerase (RdRp) is important for maintaining funct

246 nds the COL1A2 enhancer and is essential for RNA polymerase recruitment, without affecting JunB bindi

247 the cores of both ribosomal subunits enhance RNA polymerase ribozyme (RPR) function, as do derived ho

248 The unexpected ability of an RNA polymerase ribozyme to copy RNA into DNA has ramific

249 A highly evolved RNA polymerase ribozyme was found to also be capable of

250 ide-analog inhibitor that inhibits bacterial RNA polymerase (RNAP) and exhibits antibacterial activit

251 Here we show that RNA polymerase (RNAP) and the ribosome of Escherichia co

252 ought to involve direct interactions between RNA polymerase (RNAP) and the translational machinery.

253 s an accessible rut site promotes pausing of RNA polymerase (RNAP) at a single Rho-dependent terminat

254 S531 of Escherichia coli RNA polymerase (RNAP) beta subunit is a part of RNA bind

255 During transcription initiation, RNA polymerase (RNAP) binds to promoter DNA, unwinds pro

256 id and selective inhibition of the bacterial RNA polymerase (RNAP) by the 7 kDa T7 protein Gp2.

257 RNA polymerase (RNAP) expedites the recognition of DNA d

258 s globally regulate transcription by binding RNA polymerase (RNAP) holoenzyme and competing with prom

259 ss I TAC containing a CAP dimer, a sigma(70)-RNA polymerase (RNAP) holoenzyme, a complete class I CAP

260 paratus is closely related to the eukaryotic RNA polymerase (RNAP) II system, while archaeal genomes

261 The Escherichia coli RNA polymerase (RNAP) is a multisubunit protein complex

262 The mycobacteria RNA polymerase (RNAP) is a target for antimicrobials aga

263 tistep transcription process, the elongating RNA polymerase (RNAP) is dislodged from the DNA template

264 Mtb RNA polymerase (RNAP) is the target of the first-line an

265 Bacterial RNA polymerase (RNAP) requires sigma factors to recogniz

266 perinfection by coliphage lambda by stalling RNA polymerase (RNAP) translocation specifically on lamb

267 We demonstrate that MglA-SspA, which binds RNA polymerase (RNAP), also interacts with the C-termina

268 hich results from the RpoB S531L mutation in RNA polymerase (RNAP), has become a growing problem worl

269 te transcription via direct interaction with RNA polymerase (RNAP), we deep sequenced an E. coli geno

270 The bacterial RNA polymerase (RNAP), which catalyzes transcription, ca

271 a factors confer promoter specificity to the RNA polymerase (RNAP).

272 pin adjacent to a weak RNA-DNA hybrid within RNA polymerase (RNAP).

273 logs of beta and beta' subunits of bacterial RNA polymerase (RNAP).

274 transcription initiation by Escherichia coli RNA polymerase (RNAP; alpha2betabeta'omegasigma(70)), we

275 The secondary channel (SC) of multisubunit RNA polymerases (RNAPs) allows access to the active site

276 Single-subunit RNA polymerases (RNAPs) are present in phage T7 and in m

277 Evolution-related multisubunit RNA polymerases (RNAPs) carry out RNA synthesis in all d

278 The active site of multisubunit RNA polymerases (RNAPs) is highly conserved from humans

279 All cellular RNA polymerases (RNAPs), from those of bacteria to those

280 d's ability to preferentially act on stalled RNA polymerases (RNAPs).

281 Gene transcription is carried out by RNA polymerases (RNAPs).

282 of the nuclear encoded genes for chloroplast RNA polymerases RPOTp and RPOTmp suggests that the hormo

283 ilis is governed by a cascade of alternative RNA polymerase sigma factors.

284 sage suppression of essential genes encoding RNA polymerase subunits and chromosome cohesion complex

285 l domain (NGN) binds at the central cleft of RNA polymerase surrounded by the beta' clamp helices, th

286 tural protein 5B (NS5B) is the RNA-dependent RNA polymerase that catalyzes replication of the hepatit

287 Accordingly, a mutation in RNA polymerase that diminished the impact of AT-rich DNA

288 present a generative, probabilistic model of RNA polymerase that fully describes loading, initiation,

289 by providing examples of (i) selection of T7 RNA polymerases that recognize orthogonal promoters and

290 re we determined the crystal structure of an RNA polymerase, the bacterial enzyme from Thermus thermo

291 omotes transcription mediated by all nuclear RNA polymerases, thereby acting as a positive modifier o

292 from the NusG family bind to the elongating RNA polymerase to enable synthesis of long RNAs in all d

293 etylation that promotes the accessibility of RNA polymerases to the gene promoters.

294 heterogeneity features predicted activity of RNA polymerase transcription (AUC = 0.62, p=0.03) and in

295 non-template strand reduces the yield of T7 RNA polymerase transcription by more than an order of ma

296 g ribozymes and tRNA could be expressed from RNA polymerase type II (pol II) promoters such as generi

297 ector portion of the RdDM pathway, including RNA POLYMERASE V (POL V), DOMAINS REARRANGED METHYLTRANS

298 on DOMAINS REARRANGED METHYLASE 2 (DRM2) and RNA polymerase V (Pol V), two main actors of RNA-directe

299 omes at several tested loci, indicating that RNA polymerase V-related functions are impaired in the p

300 RNA-directed DNA methylation (RdDM) through RNA Polymerase V.