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1 hat form a TFIIF-related subcomplex in yeast RNA polymerase I.
2 that BLM interacts with RPA194, a subunit of RNA polymerase I.
3 the TATA-binding protein in transcription by RNA polymerase I.
4 e of the essential transcription factors for RNA polymerase I.
5 lar mechanisms that control transcription by RNA polymerase I.
6 at the rDNA because of a barrier imposed by RNA polymerase I.
7 segment analogue from a plasmid is driven by RNA polymerase I.
8 sically associated with Fob1 and subunits of RNA polymerase I.
9 not capable of forming a stable complex with RNA polymerase I.
10 out 0.5 microM CX-5461 (CX), an inhibitor of RNA polymerase I.
11 sites (BESs) by virtue of a multifunctional RNA polymerase I.
12 ng by Rrn3 is essential for transcription by RNA polymerase I.
13 o multicopy tandem arrays and transcribed by RNA polymerase I.
25 he primary sigma subunit of Escherichia coli RNA polymerase, is a negatively charged domain that affe
27 tif A that is conserved in all RNA-dependent RNA polymerases, is a key determinant of polymerase fide
28 rRNA transcription requires, in addition to RNA polymerase I, a single DNA-binding factor, transcrip
29 A polymerases: in particular two subunits of RNA polymerase I (A14 and A43) display genetic and bioch
30 ammalian homologues of two subunits of yeast RNA polymerase I, A34.5 and A49, that form a TFIIF-relat
32 aramutation1), which encodes a RNA-dependent RNA polymerase, is absolutely required for establishing
33 s a protein closely related to RNA-dependent RNA polymerases, is absolutely required for paramutation
34 eotide incorporation during transcription by RNA polymerase is accompanied by pyrophosphate formation
35 Incorporation of such compounds in RNA by RNA polymerase is accompanied by release of di- and trip
36 otein that participates in the regulation of RNA polymerase I activity and rRNA synthesis and therefo
37 nd Src can successfully rescue the defective RNA polymerase I activity induced by the loss of kindlin
39 To fully define the factors that control RNA polymerase I activity, biochemical analyses using pu
45 eterotrimeric viral PA/PB1/PB2 RNA-dependent RNA polymerase is an attractive target for a challenging
51 DEXH/D-box protein shown to function in both RNA polymerase I and polymerase II transcript metabolism
52 in Saccharomyces cerevisiae is performed by RNA polymerase I and regulated by changes in growth cond
53 titers in embryonated chicken eggs, between RNA polymerase I and RNA polymerase II transcription uni
54 was to bring together the world's experts on RNA polymerase I and RNA polymerase III to highlight and
55 ly, rDNA silencing required transcription by RNA polymerase I and the direction of spreading was cont
56 l is that Rrn3 functions as a bridge between RNA polymerase I and the transcription factors bound to
57 phosphorylation facilitates transcription by RNA polymerases I and II and has an unanticipated functi
59 ubunits of Arabidopsis thaliana multisubunit RNA polymerases I and III (abbreviated as Pol I and Pol
60 e Ninth International Biennial Conference on RNA Polymerases I and III (the "OddPols") was held on Ju
61 Eighth International Biennial Conference on RNA polymerases I and III (the 'Odd Pols') was held June
62 xpanding the usual topics on the advances in RNA polymerases I and III research to include presentati
66 ich was remedied by the addition of purified RNA polymerase I, and an anti-p31 serum completely block
67 Nevertheless, p31 cosedimented with purified RNA polymerase I, and RNA interferance-mediated silencin
68 Rrn3 interacts with the rpa43 subunit of RNA polymerase I, and treatment with cycloheximide inhib
69 onuclin deficiency in oocytes perturbed both RNA polymerase I- and II-mediated transcription, and ooc
72 se Ibeta complex and interacts directly with RNA polymerase I-associated transcription factor RRN3, w
74 verexpressed in some cancers, interacts with RNA Polymerase I, associates with active ribosomal RNA g
75 l domain of the alpha subunit (alpha-CTD) of RNA polymerase is at least partially dispensable for Rha
76 nuclease activity of influenza RNA-dependent RNA polymerase is attractive for the development of new
77 the synthesis of rRNA by inactivation of the RNA polymerase I basal transcription factor RRN3/TIF-IA.
78 the fact that the vast majority of sigma(70)-RNA polymerase is bound by 6S RNA during stationary phas
79 romatin containing rRNA genes transcribed by RNA polymerase I but not with genes transcribed by RNA p
80 s inactivated Rrn3 not only dissociates from RNA polymerase I, but is not capable of forming a stable
82 observations suggest that treacle might link RNA polymerase I-catalyzed transcription and post-transc
83 (DSB) occurs and either a DNA polymerase or RNA polymerase is coming along, how do we save the train
84 red that Mybbp1a is associated with both the RNA polymerase I complex and the ribosome biogenesis mac
85 us recessive mutations in TAF1A, encoding an RNA polymerase I complex protein, were associated with m
87 ous study showed that during optimal growth, RNA polymerase is concentrated into transcription foci o
88 chanism of substrate loading in multisubunit RNA polymerase is crucial for understanding the general
89 uncover a role for topoisomerase IIalpha in RNA polymerase I-directed ribosomal RNA gene transcripti
90 box RNA helicase in the multistep process of RNA polymerase I-directed transcription of the ribosomal
95 ectly to the housekeeping holoenzyme form of RNA polymerase (i.e. sigma70-RNA polymerase in E. coli).
96 del that Spt4/5 may contribute to pausing of RNA polymerase I early during transcription elongation b
98 e transcription fidelity by Escherichia coli RNA polymerase: (i) enhanced suppression of nucleotide m
101 osition DksA in the secondary channel of the RNA polymerase is essential for the resistance of Salmon
102 by the nuclear-encoded mitochondrial poly(A) RNA polymerase, is essential for maintaining mitochondri
103 ation of transcription mediated by all three RNA polymerases is essential for c-Myc-driven proliferat
110 r with his presentation "Conservation of the RNA polymerase I, II and III transcription initiation ma
112 DNA locus containing transcription units of RNA polymerases I, II or III or an autonomous replicatio
113 did high levels of actinomycin D (to inhibit RNA polymerases I, II, and III) or alpha-amanitin (to in
114 s found in basal transcription machinery for RNA polymerases I, II, and III, pol II transcriptional e
115 ion in the shared Rpb6 subunit, assembled in RNA polymerases I, II, and III, that illuminated a new r
117 haebacterial RNA polymerases, the eukaryotic RNA polymerases I, II, and III, the nuclear-cytoplasmic
118 tic genomes is carried out by three distinct RNA polymerases I, II, and III, whereby each polymerase
120 ribosomal biogenesis through upregulation of RNA polymerases I-, II-, and III-dependent transcription
121 level, through the coordinate regulation of RNA polymerases I-III and downstream in the coordinate r
123 ies against topoisomerase I, centromere, and RNA polymerase I/III by immunoprecipitation and/or enzym
124 antly between groups (-1.2 years in the anti-RNA polymerase I/III group, +13.4 years in the anti-topo
126 d scleroderma in patients with antibodies to RNA polymerase I/III, which is distinct from scleroderma
128 he possibility that cross-regulation between RNA polymerases is important in maintaining normal cell
130 initiated research on rRNA transcription by RNA polymerase I in the yeast Saccharomyces cerevisiae.
132 of RNA-DNA hybrid sequence by multi-subunit RNA polymerases is involved in transcription regulation
134 n that transcription of the ribosomal DNA by RNA polymerase I is a major target for cellular regulati
135 e data suggest that transcription of rRNA by RNA polymerase I is linked to rRNA processing and matura
138 ition, overexpression of the protein reduces RNA polymerase I loading on endogenous rRNA genes as rev
140 absence of CRP, suggesting that contact with RNA polymerase is maintained throughout the transcriptio
141 In bacteria, promoter identification by RNA polymerase is mediated by a dissociable sigma factor
142 R2rp1, controls DNA repair and repression of RNA polymerase I-mediated expression immediately adjacen
143 nd to the nucleolus of the cell, the site of RNA polymerase I-mediated ribosomal RNA (rRNA) transcrip
144 studies, the signaling pathways that control RNA polymerase I-mediated rRNA production are not well u
150 and PAF53 copurify with that fraction of the RNA polymerase I molecules that can function in transcri
153 nt mutation in the second largest subunit of RNA polymerase I near the active center of the enzyme th
155 at the PB2 627 domain of the influenza virus RNA polymerase is not involved in core catalytic functio
161 lpha subunit (alpha CTD) of Escherichia coli RNA polymerase is often involved in transcriptional regu
162 contrast to mRNAs, rRNAs are transcribed by RNA polymerase I or III and are not believed to be polya
163 ion in nucleotide levels or the depletion of RNA polymerase I or III subunits generates a cell cycle
164 ted that the phosphorylation of either yeast RNA polymerase I or mammalian Rrn3 regulates the formati
167 ar termination of transcription catalyzed by RNA polymerase I (pol I) and arrest of replication forks
168 Although rRNA transcriptional control by RNA polymerase I (Pol I) and associated factors is well
172 sted that after each round of transcription, RNA polymerase I (Pol I) dissociates into subunits that
173 ological change is accompanied by release of RNA polymerase I (Pol I) from the nucleolus and inhibiti
174 WI/SNF also plays a role in transcription by RNA polymerase I (Pol I) in Saccharomyces cerevisiae.
175 FA), which is essential for transcription by RNA polymerase I (Pol I) in the parasite Trypanosoma bru
176 hosphatase activity of Cdc14 is required for RNA polymerase I (Pol I) inhibition in vitro and in vivo
178 roliferation; thus, transcription of rRNA by RNA polymerase I (Pol I) is an important target for the
181 isiae's Upstream Activating Factor (UAF), an RNA polymerase I (pol I) specific transcription stimulat
182 somal RNA (rRNA) is transcribed from rDNA by RNA polymerase I (Pol I) to produce the 45S precursor of
184 genes (TCOF1, POLR1C and POLR1D) involved in RNA polymerase I (Pol I) transcription account for more
186 a nucleolar protein that associates with the RNA polymerase I (Pol I) transcription machinery to supp
187 oximal unique sequence located downstream of RNA polymerase I (Pol I) transcription, but fails to ent
188 tudy reveals that the selective inhibitor of RNA polymerase I (Pol I) transcription, CX-5461, effecti
191 the rDNA promoter through interactions with RNA polymerase I (Pol I), and to a pair of DNA replicati
193 laboratory demonstrated the critical role of RNA polymerase I (Pol I)-associated factor PAF53 in mamm
195 ucleolar DEAD/DEAH-box helicases involved in RNA polymerase I (Pol I)-mediated transcriptional activi
196 d UBF) is thought to function exclusively in RNA polymerase I (Pol I)-specific transcription of the r
197 To study the effect of CpG methylation on RNA polymerase I (pol I)-transcribed rRNA genes, we cons
198 can sleeping sickness, TbISWI down-regulates RNA polymerase I (Pol I)-transcribed variant surface gly
210 contrast, nascent pre-mRNA synthesized by T7 RNA polymerase is quantitatively assembled into the nons
212 ation, functioning in core promoter binding, RNA polymerase I recruitment, and UBF stabilization and
214 Although UBF1 has been shown to activate RNA polymerase I-regulated genes, the function of UBF2 h
215 th RNA polymerase II (with beta-catenin) and RNA polymerase I-regulated promoters suggest an explanat
216 A levels were measured along with markers of RNA polymerase I regulatory factors and regulators of pr
217 also displayed a down-regulation of several RNA polymerase I- related factors, consistent with termi
218 during mitotic growth and G0 entry, and (ii) RNA polymerase I release prevents heterochromatin format
220 Ribosomal RNA transcription mediated by RNA polymerase I represents the rate-limiting step in ri
221 The dissociable sigma subunit of bacterial RNA polymerase is required for the promoter-specific ini
222 Its interaction with the alpha-subunit of RNA polymerase is required for transcriptional induction
223 terminal domain (ATD) of yeast mitochondrial RNA polymerase is required to couple transcription to tr
226 ntly related member of the T7-like family of RNA polymerases, is responsible for transcription of the
227 e demonstrate a link between the dynamics of RNA polymerase I (RNA Pol I) assembly and transcriptiona
230 stronically transcribed by a multifunctional RNA polymerase I (RNAPI) from a short promoter that is l
232 or mammalian Rrn3 regulates the formation of RNA polymerase I.Rrn3 complexes that can interact with t
233 f the polymerase I and SL1 complexes and the RNA polymerase I-specific transcription initiation facto
234 the DFC of the nucleolus, as defined by the RNA polymerase I-specific upstream binding factor and th
236 tailed pattern of the blockage suggests that RNA polymerase is sterically hindered by H-DNA and has d
237 hown to occur cotranscriptionally, while the RNA polymerase is still actively engaged with the chroma
240 etween the locus encoding the second largest RNA polymerase I subunit and a lysine tRNA gene [i.e., R
242 cleolar disassembly started with the loss of RNA polymerase I subunits from the fibrillar centers.
243 hSpagh also bound the free RPA194 subunit of RNA polymerase I, suggesting a general role in assemblin
245 only known eukaryote with a multifunctional RNA polymerase I that, in addition to ribosomal genes, t
247 The twisting of DNA due to the movement of RNA polymerases is the basis of numerous classic experim
249 odulates rDNA structures in association with RNA polymerase I to facilitate RNA polymerase I-mediated
252 important function of nucleolin is to permit RNA polymerase I to transcribe nucleolar chromatin.
253 ved in the transcriptional regulation of the RNA polymerase I transcribed variant surface glycoprotei
255 h a variety of cellular processes, including RNA polymerase I transcription and cell cycle progressio
256 reates a chromatin environment permissive to RNA polymerase I transcription and nascent rRNA processi
257 localization of this complex requires active RNA polymerase I transcription and the small ubiquitin-l
258 a reverse genetics system in which the eight RNA polymerase I transcription cassettes for viral RNA s
262 how that nucleolar SmgGDS interacts with the RNA polymerase I transcription factor upstream binding f
265 we evaluate the exchange kinetics of several RNA polymerase I transcription factors and nucleosome co
266 and second, coevolution of IGS sequence with RNA polymerase I transcription factors may lead to speci
268 ransduction, while a just-published study of RNA polymerase I transcription has implicated polymeric
271 ng a putative Rrn11p homolog, SpRrn11h, bear RNA polymerase I transcription initiation factor activit
272 Knowledge of the role of components of the RNA polymerase I transcription machinery is paramount to
274 ase I, we demonstrated that nucleolin allows RNA polymerase I transcription of chromatin templates in
275 related to nucleolar chromatin structure and RNA polymerase I transcription regulation, rRNA processi
276 cleophosmin (NPM/B23), RNA helicase DDX5 and RNA polymerase I transcription termination factor (TTF-I
277 pose that topoisomerase IIalpha functions in RNA polymerase I transcription to produce topological ch
283 role of integrin signaling in regulation of RNA polymerase I transcriptional activity and shed light
284 re we provide original evidence showing that RNA polymerase I transcriptional activity is tightly con
286 inhibits a subset of metalloenzymes and that RNA polymerase is unlikely to be the primary target.
287 ion of the same set of genes by two types of RNA polymerases is unprecedented for a bacteriophage.
290 cleolin localizes primarily to nucleoli with RNA polymerase I, we demonstrated that nucleolin allows
292 site Trypanosoma brucei is a multifunctional RNA polymerase I which, in addition to synthesizing rRNA
293 in a complex that regulates the activity of RNA polymerase I, which controls the rate of ribosomal R
295 tion of a TCOF1-NOLC1 platform that connects RNA polymerase I with ribosome modification enzymes and
296 genes (PAGs), these being co-transcribed by RNA polymerase I with the procyclin surface antigen gene
297 ion assays, we found that the association of RNA polymerase I with the promoter and the coding region
299 aptamers were transcribed at high levels by RNA polymerase I without any additional promoter being i
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