ライフサイエンスコーパス: RNA polymerase II

1 regulatory element for genes transcribed by RNA polymerase II.

2 ccessibility for transcription initiation by RNA polymerase II.

3 uired for the transcription of most genes by RNA polymerase II.

4 that Cuff prevents premature termination of RNA polymerase II.

5 the same time and place as transcription by RNA polymerase II.

6 in particular, contribute to the pausing of RNA polymerase II.

7 ation of the start site for transcription by RNA polymerase II.

8 d by binding defects to both nucleosomes and RNA polymerase II.

9 osphorylating the carboxy-terminal domain of RNA polymerase II.

10 and in the transcription of coding genes by RNA polymerase II.

11 minal domain (CTD) of the largest subunit of RNA polymerase II.

12 o the expression of all genes transcribed by RNA polymerase II.

13 associate with the core mediator complex of RNA polymerase II.

14 ike domain (PLD) to the C-terminal domain of RNA polymerase II.

15 recruited a significant fraction of cellular RNA polymerase II.

16 ted with Set1 (COMPASS) to promoter-proximal RNA polymerase II.

17 or (Inr), direct transcription initiation by RNA polymerase II.

18 ex, which regulates transcription pausing of RNA-polymerase II.

19 ve genes and disrupted recruitment of active RNA polymerase II, a property shared with pan-BETis that

20 Moreover, Piwi influences RNA polymerase II activities in Drosophila ovaries, like

21 ortem brain, and pharmacologic modulation of RNA polymerase II activity altered repetitive element ex

22 We conclude that increased RNA polymerase II activity in ALS/FTLD may lead to incre

23 lement expression positively correlated with RNA polymerase II activity in postmortem brain, and phar

24 ay decreased heterochromatin domains, a high RNA-polymerase II activity and enhanced c-Fos expression

25 ckdown of FoxA1 similarly reduced binding of RNA polymerase II and FoxO1.

26 einitiation complex (PIC), which consists of RNA polymerase II and general transcription factors.

27 We found that ChIP-seq data of RNA polymerase II and histone modifications were particu

28 erexpression of FOXC1 hinders recruitment of RNA polymerase II and increases histone H3K9 trimethylat

29 machinery allowing O-GlcNAc accumulation on RNA polymerase II and numerous chromatin factors includi

30 TFIID binds promoter DNA to recruit RNA polymerase II and other basal factors for transcript

31 EJ proteins form a multiprotein complex with RNA polymerase II and preferentially associate with the

32 ides, and coincide spatially with elongating RNA polymerase II and splicing components.

33 ere was a significantly reduced occupancy of RNA polymerase II and the essential mitotic transcriptio

34 ntified transcriptome-wide binding sites for RNA polymerase II and the exosome cofactors Mtr4 (TRAMP

35 al cancer cells as marked by the presence of RNA polymerase II and the histone marker H3K27Ac.

36 DG8 with the transcription machinery, namely RNA polymerase II and the PAF1 complex.

37 HepG2 cells significantly reduces binding of RNA polymerase II and the pioneer factors FoxA1/A2.

38 romatin reassembly in the wake of elongating RNA polymerase II and transcriptional elongation, thus r

39 Dynamic interactions between RNA polymerase II and various mRNA-processing and chroma

40 to form mediator complexes, phosphorylating RNA polymerase II, and by its intrinsic histone acetyltr

41 tes as a "speed bump" against advancement of RNA polymerase II, and temperature stress releases the b

42 be a master coordinator of transcription by RNA polymerase II, and this complex is recruited by tran

43 ive viral transcription by focal assembly of RNA polymerase II around Kaposi's sarcoma-associated her

44 We propose that the assembly of RNA polymerase II around viral episomes in the nucleus m

45 a, C/EBPalpha, PPARgamma), coactivator MED1, RNA polymerase II, as well as epigenome (H3K4me1/2/3, H3

46 In absence of HBV replication, RNA polymerase II associated with SALL4 exon1.

47 man cells is funneled through Integrator, an RNA polymerase II-associated complex.

48 function of VIP proteins, components of the RNA polymerase II-associated factor 1 complex (Paf1c).

49 Our data also revealed that RNA-polymerase-II-associated proteins like PAF1 and RTF1

50 suppressed the initiation and elongation of RNA polymerase II at active genes genome-wide, with pron

51 mine the first room-temperature structure of RNA polymerase II at high resolution, revealing new stru

52 ng active chromatin state and recruitment of RNA polymerase II at mutant TERT promoters.

53 gatively impacts levels of promoter-proximal RNA polymerase II at protein-coding (pc) genes.

54 EFb and thereby prevented phosphorylation of RNA polymerase II at Ser2 and productive elongation.

55 n, both FUS and TDP43 colocalize with active RNA polymerase II at sites of DNA damage along with the

56 In metazoans, the pausing of RNA polymerase II at the promoter (paused Pol II) has em

57 al factories" decreased the pool of cellular RNA polymerase II available for cellular gene transcript

58 TFIIH is a 10-subunit RNA polymerase II basal transcription factor with a dual

59 Increases in RNA polymerase II binding and mRNA abundances for Aqp2 f

60 ion experiments showed that the abundance of RNA polymerase II binding to the intron-less construct i

61 ssin treatment was associated with increased RNA polymerase II binding to the promoter proximal regio

62 ithin NuA4 to be important for both NuA4 and RNA polymerase II binding.

63 ion by recruiting Argonaute 2 and inhibiting RNA polymerase II binding.

64 In addition, through its interaction with RNA Polymerase II C-terminal domain (CTD) and affecting

65 The RNA polymerase II C-terminal domain phosphatase-like pro

66 ylglucosamine (O-GlcNAc) modification of the RNA polymerase II C-terminal domain was described 20 yea

67 on elongation through phosphorylation of the RNA polymerase II C-terminal domain.

68 pitation experiments revealed that the Ssu72 RNA polymerase II carboxyl-terminal domain phosphatase,

69 ifferent physiological signals manifested by RNA polymerase II carboxyl-terminal domain phosphorylati

70 A) silencing by inhibiting recombination and RNA polymerase II-catalyzed transcription in the rDNA of

71 that both enhancer classes are enriched for RNA Polymerase II, CBP, and architectural proteins but t

72 of higher-order chromatin structure data and RNA polymerase II ChIA-PET data from MCF-7 cells did not

73 Here, we analyze 85 RNA polymerase II chromatin immunoprecipitation (ChIP)-s

74 RNA polymerase II contains a long C-terminal domain (CTD

75 RNA polymerase II contains a repetitive, intrinsically d

76 Here we provide an overview of the RNA polymerase II core promoter in bilateria (bilaterall

77 denylation factor SYDN-1, which inhibits the RNA polymerase II CTD phosphatase SSUP-72.

78 orylation sites on the tandem repeats of the RNA polymerase II CTD.

79 or the regulated transcription of nearly all RNA polymerase II-dependent genes.

80 with PC4 and cofilin, which are involved in RNA polymerase II-dependent transcription.

81 y initiate transcription but generate paused RNA polymerase II downstream from the start site.

82 ive elongation factor (NELF) associates with RNA polymerase II during early elongation and causes RNA

83 Convergent transcription causes stalling of RNA polymerase II during transcription, which permits ER

84 3 binding, recruitment of BRG1, and enhanced RNA polymerase II elongation and SALL4 transcription.

85 troller for transcription activation through RNA polymerase II elongation at a subset of genomic piRN

86 ucleoprotein (snRNP) plays a central role in RNA polymerase II elongation control by regulating the a

87 zation of the enzyme O-GlcNAcase (OGA) as an RNA polymerase II elongation factor.

88 several lines of evidence showing that slow RNA polymerase II elongation increases both cotranscript

89 Moreover, we demonstrate that altering the RNA polymerase II elongation rate in either direction co

90 RNA synthesis, transcription initiation and RNA polymerase II elongation.

91 undance of the active/elongating form of the RNA polymerase-II enzyme (RNAPII-Ser2P), together with C

92 ed state among paused, initiating eukaryotic RNA polymerase II enzymes.

93 a "non-canonical" form of RdDM dependent on RNA polymerase II expression to initiate and re-establis

94 We found that RNA polymerase II expression-dependent forms of RdDM fun

95 exit of MKL, and sequestration of p65 at the RNA-polymerase-II foci.

96 trotransposons, begins with transcription by RNA polymerase II followed by reverse transcription and

97 eneral transcriptional machinery required by RNA polymerase II for the initiation of eukaryotic gene

98 Processive elongation of RNA Polymerase II from a proximal promoter paused state

99 5'-3' gene looping previously described for RNA polymerase II genes.

100 LR2A, which encodes the catalytic subunit of RNA polymerase II, hijack this essential enzyme and driv

101 n cryo-electron microscopy map of a Mediator-RNA polymerase II holoenzyme reveals that changes in the

102 TREX is loaded on nascent RNA transcribed by RNA polymerase II in a splicing-dependent fashion; howev

103 ncy of GR, the p65 subunit of NF-kappaB, and RNA polymerase II in airway epithelial cells treated wit

104 scernable decrease in the elongating form of RNA polymerase II in either mutant.

105 The C-terminal domain (CTD) of RNA polymerase II in eukaryotes is comprised of tandemly

106 g signals from transcriptional regulators to RNA polymerase II in eukaryotes.

107 ation by confiscation of a limited supply of RNA polymerase II in infected cells.IMPORTANCE B cells i

108 role of a previously ill-defined species of RNA polymerase II in regulating transcription.

109 H3 trimethylated at lysine 27 (H3K27me3) and RNA polymerase II in wild-type and piwi mutant ovaries d

110 wnregulated CDK7-mediated phosphorylation of RNA polymerase II, indicative of transcriptional inhibit

111 ugh recruitment of co-activators such as the RNA polymerase II-interacting Mediator complex.

112 tor protein) is an unconventional prefoldin, RNA polymerase II interactor that functions as a transcr

113 The release of paused RNA polymerase II into productive elongation is highly r

114 RNA polymerase II is engaged with promoter regions prior

115 matin occupancy of serine 2-unphosphorylated RNA polymerase II is increased, and that of topoisomeras

116 We propose that transcription by RNA polymerase II is tuned to optimize the efficiency an

117 The RNA polymerase II largest subunit C-terminal domain cons

118 finding revealed that the exosomes increase RNA polymerase II loading onto the HIV-1 promoter in the

119 miR-200 overexpression induced RNA polymerase II localization and reduced Zeb2 and Snai

120 tive SINE elements residing within annotated RNA Polymerase II loci.

121 cally links enhancer-bound activators to the RNA polymerase II machinery at the core promoter.

122 OUP-TFII was regulated by ensuring efficient RNA polymerase II machinery binding.

123 transcription factor TFIIH and initiation of RNA polymerase II mediated transcription.

124 RNA polymerase II mediates the transcription of all prot

125 d kinetics of post-translational histone and RNA polymerase II modifications.

126 OCSs correlate with RNA polymerase II occupancy and active chromatin marks,

127 H3K4me3, and H3K27me3, DNA methylation, and RNA polymerase II occupancy and perform transcriptome an

128 tome profiling, chromatin accessibility, and RNA polymerase II occupancy demonstrate that BTBD18 faci

129 By contrast, in HBV replicating cells RNA polymerase II occupancy of all SALL4 exons increased

130 chromatin immunoprecipitation (ChIP) assays RNA polymerase II occupancy of SALL4 gene, as a function

131 Although dexamethasone treatment reduced RNA polymerase II occupancy of TNF targets such as IL8 a

132 Furthermore, RNA polymerase II occupancy was decreased only under con

133 ablation of FHL2 facilitates recruitment of RNA polymerase II on the TGF-beta1 promoter, suggesting

134 ese genes and controls the loading of active RNA polymerase II onto these promoters.

135 PR) single guide RNAs (sgRNAs) from a single RNA polymerase II or III transcript in Drosophila.

136 pendent and is mediated through reduction of RNA polymerase II pause release.

137 rovide new insights into the contribution of RNA polymerase II pausing in mammalian gene regulation a

138 n be activated by decreasing the duration of RNA polymerase II pausing in the promoter-proximal regio

139 many proteins, and mechanisms, ranging from RNA Polymerase II pausing to cotranscriptional histone m

140 tion between one specific enhancer state and RNA Polymerase II pausing, linking transcription regulat

141 tes inclusion of weak upstream exons through RNA polymerase II pausing, whereas 5-methylcytosine evic

142 ion factors EBF1, EGR1 or MEF2C depending on RNA Polymerase II pausing.

143 acts with transcription initiation-competent RNA polymerase II phosphorylated at Ser-5 in a DNA templ

144 Here we employ a set of RNA Polymerase II (Pol II) activity mutants to determine

145 changes are suppressed by the inhibition of RNA polymerase II (Pol II) activity.

146 oding genes in eukaryotes are transcribed by RNA polymerase II (Pol II) and introns are removed from

147 During mitosis, RNA polymerase II (Pol II) and many transcription factor

148 ge preinitiation complex (PIC) that includes RNA polymerase II (Pol II) and the general transcription

149 genes there was constitutive association of RNA polymerase II (Pol II) and the general transcription

150 alyses have uncovered a high accumulation of RNA polymerase II (Pol II) at the 5' end of genes.

151 The dynamics of the RNA polymerase II (Pol II) backtracking process is poorl

152 nitiation, the TFIIH-kinase Kin28/Cdk7 marks RNA polymerase II (Pol II) by phosphorylating the C-term

153 Phosphorylation of the RNA polymerase II (Pol II) C-terminal domain (CTD) regul

154 orylates the termination factor PCF11 on its RNA polymerase II (Pol II) C-terminal domain (CTD)-inter

155 n between mRNA synthesis and the dynamics of RNA Polymerase II (Pol II) clusters at a gene locus.

156 te the degradation of Rpb1, a subunit of the RNA polymerase II (Pol II) complex, and therefore hamper

157 The transcription cycle of RNA polymerase II (Pol II) correlates with changes to th

158 n (ChIP) and chemical inhibitor studies that RNA polymerase II (Pol II) elongation is important for e

159 RNA polymerase II (pol II) encounters numerous barriers

160 acts upstream of promoter-proximally paused RNA polymerase II (Pol II) formation (likely at the step

161 Live cell imaging of mammalian RNA polymerase II (Pol II) has previously relied on rand

162 omatin immunoprecipitation of histone H3 and RNA polymerase II (Pol II) in mutants lacking single or

163 facilitate ubiquitylation and degradation of RNA polymerase II (pol II) in response to multiple stimu

164 ctors, which utilize P-TEFb to phosphorylate RNA polymerase II (Pol II) in response to stimuli.

165 rs promoter-proximal accumulation/pausing of RNA polymerase II (Pol II) independently of its capping

166 Transcription by RNA polymerase II (Pol II) is a complex process that req

167 Promoter-proximal pausing by RNA polymerase II (Pol II) is a key rate-limiting step i

168 Transcription by RNA polymerase II (Pol II) is dictated in part by core p

169 The transcription cycle of RNA polymerase II (Pol II) is regulated at discrete tran

170 Ongoing transcription by cellular RNA polymerase II (Pol II) is required for viral mRNA sy

171 Transcription by RNA polymerase II (Pol II) is required to produce mRNAs

172 association of DSIF and NELF with initiated RNA Polymerase II (Pol II) is the general mechanism for

173 Elongation of RNA polymerase II (Pol II) is thought to be an important

174 e identification and characterization of the RNA polymerase II (Pol II) kinase Cdk12 as a factor that

175 The carboxy-terminal domain (CTD) of the RNA polymerase II (Pol II) large subunit cycles through

176 trap optical tweezers to study single yeast RNA polymerase II (Pol II) molecules transcribing along

177 n of this mechanism unexpectedly showed that RNA polymerase II (Pol II) occupancy changes at FLC did

178 diated PRC eviction occurs in the absence of RNA polymerase II (Pol II) occupancy, transcription, and

179 minal domain (CTD) of the largest subunit of RNA polymerase II (Pol II) orchestrates dynamic recruitm

180 RNA polymerase II (Pol II) pauses downstream of the tran

181 on P-TEFb recruitment and the regulation of RNA polymerase II (Pol II) pausing.

182 5' end of those genes with promoter-proximal RNA polymerase II (Pol II) pausing.

183 OGA is physically associated with the known RNA polymerase II (pol II) pausing/elongation factors SP

184 The promoter-proximal pausing of RNA polymerase II (Pol II) plays a critical role in regu

185 In parallel, Brd4 temporally controls RNA polymerase II (Pol II) processivity during transcrip

186 Gene expression in metazoans is regulated by RNA polymerase II (Pol II) promoter-proximal pausing and

187 While the nucleosome positioning at RNA polymerase II (pol II) promoters has been extensivel

188 Transcription activation involves RNA polymerase II (Pol II) recruitment and release from

189 Active NL genes with higher RNA polymerase II (Pol II) recruitment levels tend to di

190 iption is regulated at many steps, including RNA polymerase II (Pol II) recruitment, transcription in

191 RNA Polymerase II (Pol II) regulatory cascades involving

192 described 20 years ago, the function of this RNA polymerase II (pol II) species is not known.

193 Rpb9 is a conserved RNA polymerase II (pol II) subunit, the absence of which

194 tory step in gene expression, which requires RNA polymerase II (pol II) to escape promoter proximal p

195 In eukaryotes, RNA polymerase II (pol II) transcribes all protein-codin

196 The RNA polymerase II (Pol II) transcription elongation fact

197 Termination of RNA polymerase II (Pol II) transcription is an important

198 tisense RNAs are a mechanistic by-product of RNA polymerase II (Pol II) transcription or biologically

199 RNA polymerase II (Pol II) transcription termination by

200 ) are generated from the mammalian genome by RNA polymerase II (Pol II) transcription.

201 ator plays an integral role in activation of RNA polymerase II (Pol II) transcription.

202 Termination of Saccharomyces cerevisiae RNA polymerase II (Pol II) transcripts occurs through tw

203 RNA polymerase II (pol II) utilizes a complex interactio

204 eal globally elevated levels of transcribing RNA Polymerase II (Pol II) within genes in both species.

205 atin reorganization surrounding transcribing RNA polymerase II (Pol II), and using asymmetric nucleos

206 n that directly binds the largest subunit of RNA polymerase II (pol II), Rpb1, in response to phospho

207 By profiling the genome-wide binding of RNA polymerase II (Pol II), TaDa can also identify trans

208 D) plays a central role in the initiation of RNA polymerase II (Pol II)-dependent transcription by nu

209 t a robust genome-wide approach for studying RNA polymerase II (Pol II)-mediated transcription in hum

210 RNA polymerase II (Pol II)-transcribed genes embedded wi

211 find that 6mA is exclusively associated with RNA polymerase II (Pol II)-transcribed genes, but is not

212 that regulates promoter-proximal pausing by RNA polymerase II (Pol II).

213 ly characterized interaction between p53 and RNA polymerase II (Pol II).

214 ple general transcription factors (GTFs) and RNA polymerase II (Pol II).

215 template strand that block translocation of RNA polymerase II (Pol II).

216 cent transcripts in promoter-proximal paused RNA polymerase II (Pol II).

217 ucers and their relationship to transcribing RNA polymerase II (Pol2) could provide new insights abou

218 RNA polymerase II (Pol2) movement through chromatin and

219 tudy, we identified carboxyl-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (SCP

220 te, 52-protein, 2.5 million dalton, Mediator-RNA polymerase II pre-initiation complex (Med-PIC) was a

221 structure and promoter recruitment of poised RNA polymerase II preinitiation complex (RNAPII PIC), wh

222 of nucleosome sliding activity or changes in RNA polymerase II processivity.

223 in wild-type and mutant yeast cells in which RNA polymerase II promoter escape is blocked, allowing d

224 acterium ND2006 (Lb) in plants, using a dual RNA polymerase II promoter expression system.

225 non-coding RNA hyperproduction from cryptic RNA polymerase II promoters; (ii) alterations in recombi

226 cient binding to DNA templates, facilitating RNA polymerase II recruitment and frequent reutilization

227 sses such as transcription factor occupancy, RNA polymerase II recruitment and initiation, nascent tr

228 pho-p65 or phospho-CREB and CBP bindings and RNA polymerase II recruitment to these promoters in mesa

229 sor complex to de-acetylate H3K9 and repress RNA polymerase II recruitment.

230 ecome enriched at RA target genes to promote RNA polymerase II recruitment.

231 hock-induced genes and does so by increasing RNA polymerase II release from promoter-proximal pause.

232 lymerase in cycling and quiescent cells: (i) RNA polymerase II release mediates heterochromatin forma

233 Fusing Set1 to RNA polymerase II results in H3K4me2 throughout transcri

234 A unique feature of RNA polymerase II (RNA pol II) is its long C-terminal ex

235 in an interactome predominantly comprised of RNA Polymerase II (RNA Pol II) transcriptional machinery

236 is essential for transcription initiation by RNA polymerase II (RNA pol II) via direct interaction wi

237 ng the General Transcription Factors (GTFs), RNA polymerase II (RNA pol II), co-activators, co-repres

238 f recent studies detailing the mechanisms of RNA polymerase II (RNA Pol II)-based transcriptional ini

239 Eukaryotic gene expression requires that RNA Polymerase II (RNAP II) gain access to DNA in the co

240 (ChIP) studies illustrated that M inhibited RNA polymerase II (RNAP II) recruitment to gene promoter

241 nactive clusters based on the enrichment for RNA polymerase II (RNAPII) and H3K9me3, respectively.

242 is a conserved protein that colocalizes with RNA polymerase II (RNAPII) and has been shown to be impo

243 ssociated with genes actively transcribed by RNA polymerase II (RNAPII) and is catalyzed by Saccharom

244 Interestingly, MLL2 interacts with RNA polymerase II (RNAPII) and RECQL5, and, although MLL

245 IS-only sites) are, on average, enriched for RNA polymerase II (RNAPII) binding and histone retention

246 nt and the accumulation of P-TEFb-associated RNA polymerase II (RNAPII) C-terminal domain (CTD)-Ser7

247 (H3K4me3) in transcriptional events such as RNA polymerase II (RNAPII) elongation and alternative sp

248 nitiation and regulation of transcription by RNA polymerase II (RNAPII) in eukaryotes rely on the tra

249 transcript elongation of subsets of genes by RNA polymerase II (RNAPII) in the chromatin context.

250 Release of promoter-proximally paused RNA polymerase II (RNAPII) is a recently recognized tran

251 l histone modifications (H3K4me3, H2A.Z) and RNA polymerase II (RNAPII) occupancy.

252 RNA polymerase II (RNAPII) passes through the nucleosome

253 B) is a BRCA1-binding protein that regulates RNA polymerase II (RNAPII) pausing and transcription elo

254 es are at promoters that have high levels of RNA polymerase II (RNAPII) stalling and DNA accessibilit

255 Given that the elongating RNA polymerase II (RNAPII) stalls at this well positione

256 7, regulates the mRNA elongation capacity of RNA polymerase II (RNAPII) through controlling the nucle

257 Termination of RNA polymerase II (RNAPII) transcription is associated w

258 RNA polymerase II (RNAPII) undergoes structural changes

259 ion of the carboxyl-terminal-domain (CTD) of RNA polymerase II (RNAPII) with stimulation of TOP1 abov

260 t of PRC-bound genes actively transcribed by RNA polymerase II (RNAPII).

261 feration and migration, and to interact with RNA Polymerase II (RNAPII).

262 e coding strand of genes block elongation by RNA polymerase II (RNAPII).

263 vealed that nucleosomes impede elongation of RNA polymerase II (RNAPII).

264 e beta-tubulin (BenA), calmodulin (CaM), and RNA polymerase II second largest subunit (RPB2) genes.

265 ar large subunit (LSU) of ribosomal DNA, the RNA polymerase II second-largest subunit (RPB2), and the

266 bed with 12 pure proteins (80 polypeptides): RNA polymerase II, six general transcription factors, TF

267 assembly of large protein complexes, such as RNA polymerase II, small nucleolar ribonucleoproteins an

268 increased binding of total and phospho-Ser2 RNA polymerase II specifically at the intron retained un

269 For many genes, RNA polymerase II stably pauses before transitioning to

270 revisiae Spt6 binds the linker region of the RNA polymerase II subunit Rpb1 rather than the expected

271 tyrosyl-DNA-phosphdiesterase, and TAF12, an RNA polymerase II TATA-box binding factor, cause CIN whe

272 as established a role of base J in promoting RNA polymerase II termination in Leishmania spp. where t

273 Upon inhibiting RNA polymerase II termination via depletion of the cleav

274 plexes and recruit coactivator complexes and RNA polymerase II, thereby inducing transcription.

275 RNA polymerase II therefore navigates hundreds of base p

276 e super-enhancer signature and elongation of RNA polymerase II through the Hand2 enhancer locus.

277 y decreased recruitment of NF-kappaB p65 and RNA polymerase II to COX-2 and IL-8 promoters.

278 based mutagenesis reduced the recruitment of RNA polymerase II to ENL-target genes, leading to the su

279 complex, which results in the recruitment of RNA polymerase II to initiate transcription.

280 tion of DNA replication per se or loading of RNA polymerase II to late promoters and subsequent reduc

281 merase II during early elongation and causes RNA polymerase II to pause in the promoter-proximal regi

282 in reduced binding of actively transcribing RNA polymerase II to the endogenous Asc gene, resulting

283 normal recruitment of the initiating form of RNA polymerase II to the promoter.

284 gene activity by direct association with an RNA polymerase II-transcribed gene.

285 eneral cofactor required for essentially all RNA polymerase II transcription and is not consistent wi

286 nd found a positive correlation between both RNA polymerase II transcription and mRNA degradation wit

287 The evolutionarily conserved RNA polymerase II transcription factor D (TFIID) complex

288 The human Mediator complex regulates RNA polymerase II transcription genome-wide.

289 x has an essential role in the regulation of RNA polymerase II transcription in all eukaryotes.

290 scription factor TFIID is a key component of RNA polymerase II transcription initiation.

291 tion prevents the enrichment of Mediator and RNA polymerase II transcription machinery, but not that

292 d role of CKII and FACT in the regulation of RNA polymerase II transcription through chromatin via ph

293 d TFIID are alternative factors that promote RNA polymerase II transcription, with about 10% of genes

294 conserved coactivator complex essential for RNA polymerase II transcription.

295 somerase 1 (Top1) as a positive regulator of RNA polymerase II transcriptional activity at pathogen-i

296 f translation-competent mRNA is dependent on RNA polymerase II transcripts being modified by addition

297 bp2 on mRNA and stabilization of a subset of RNA polymerase II transcripts.

298 ChIP-Seq quantification of binding sites for RNA polymerase II was combined with RNA-Seq quantificati

299 A significant portion of cellular RNA polymerase II was trapped in these factories and ser

300 ntial mitotic transcription factor FoxM1 and RNA polymerase II were found to occupy the cyclin B1 gen