ライフサイエンスコーパス: RNA-binding domain

1 , which contains a conserved double-stranded RNA binding domain.

2 makes up almost the entirety of APO1, is an RNA binding domain.

3 cognition Motif (RRM) is the most ubiquitous RNA binding domain.

4 e common Cys(3)His zinc finger polyadenosine RNA binding domain.

5 nuclear pore protein Nup153 contains a novel RNA binding domain.

6 sociates relatively robustly with the Nup153 RNA binding domain.

7 -dimensional structure of a highly conserved RNA binding domain.

8 eat domains on either side of the C-terminal RNA binding domain.

9 eta is specifically targeted to mRNAs by its RNA binding domain.

10 ilar CCCH zinc fingers that form the primary RNA binding domain.

11 protein kinase R (PKR) independently of its RNA-binding domain.

12 was identified as a putative double-stranded RNA-binding domain.

13 ession through interactions with the Pumilio RNA-binding domain.

14 inal RNMT-activating domain and a C-terminal RNA-binding domain.

15 rginine-rich region, which overlaps with its RNA-binding domain.

16 to a response regulator (EutV) containing a RNA-binding domain.

17 K51A substitution in the Tat double-stranded RNA-binding domain.

18 ing that DUF860 is a previously unrecognized RNA-binding domain.

19 a novel Sec incorporation domain and an L7Ae RNA-binding domain.

20 omoting SECIS and eEFSec binding to the SBP2 RNA-binding domain.

21 hback) if Nanos is tethered via an exogenous RNA-binding domain.

22 on in humans, lies within a novel, bipartite RNA-binding domain.

23 ole of the N-terminal domain as an accessory RNA-binding domain.

24 otease activity or by the positively charged RNA-binding domain.

25 s suggest that EIAV Rev utilizes a bipartite RNA-binding domain.

26 as HicA (COG1724) contains a double-stranded RNA-binding domain.

27 aptation of both zinc fingers within the TTP RNA-binding domain.

28 through its RS domains but also through its RNA-binding domain.

29 RMs), the most prevalent class of eukaryotic RNA-binding domain.

30 1 US11 is a RNA-binding protein with a novel RNA-binding domain.

31 icing factors, in that they contain a single RNA-binding domain.

32 as identified within a 56 amino acid residue RNA-binding domain.

33 dopsis PUF protein that contains an atypical RNA-binding domain.

34 rotein contains two structurally independent RNA binding domains.

35 partners by the combinatorial use of several RNA binding domains.

36 one fold that is similar to that of RNP-type RNA binding domains.

37 motif (RRM), which is one of the most common RNA binding domains.

38 lectivity by ADAR1 and other proteins with Z-RNA binding domains.

39 PH (RPH) domains, one PNPase domain, and two RNA binding domains.

40 ins (RBPs), many of which lack characterized RNA binding domains.

41 n bind engineered proteins fused to specific RNA binding domains.

42 h proteins have CCCH type tandem zinc finger RNA-binding domains.

43 ences appended to their conserved PUF repeat RNA-binding domains.

44 e separate from the two pairs of zinc-finger RNA-binding domains.

45 Dicer proteins is related to double-stranded RNA-binding domains.

46 in that harbors two KH-type and one RGG-type RNA-binding domains.

47 e Dicer ribonuclease III and double-stranded RNA-binding domains.

48 ally based on a number of well-characterised RNA-binding domains.

49 st a therapeutic potential for SRSF1 and its RNA-binding domains.

50 ribosomal proteins via remodelling of their RNA-binding domains.

51 intramolecular interactions between the two RNA-binding domains.

52 to phosphorylate eIF2alpha even without its RNA-binding domains.

53 localization of oskar mRNA requires Staufen RNA binding domain 2, whereas prospero mRNA localization

54 RNA-binding domain 4 and the glycine/arginine-rich domai

55 alization mediated the binding of Miranda to RNA binding domain 5, suggesting that different Staufen

56 (zmSRp30, zmSRp31, and zmSRp32) contains two RNA binding domains, a signature sequence SWQDLKD, and a

57 lly, we also detect several proteins with an RNA-binding domain abundant in Apicomplexans (RAP domain

58 ray of octatricopeptide repeats (OPR) and an RNA-binding domain abundant in apicomplexans (RAP) domai

59 an unusual RNA-binding domain named RAP (for RNA-binding domain abundant in Apicomplexans), shared by

60 iven into an open conformation, exposing its RNA-binding domain, allowing RNA binding.

61 Furthermore, expression of the SRSF1 RNA-binding domains alone can inhibit viral replication

62 ino acids), as well as either its N-terminal RNA-binding domain (amino acids 1 to 93) or C-terminal d

63 nspecific RNA binding by the double-stranded RNA binding domain, an interaction that is essential for

64 N proteins contain two structurally distinct RNA-binding domains, an unusual characteristic among RNA

65 Rsr is composed of two domains: a helical RNA binding domain and a mixed "von Willebrand factor A-

66 rements for recognition by the high affinity RNA binding domain and an independent N-terminal RNA int

67 e PKR constructs lacking the double-stranded RNA binding domain and bind to a basic region adjacent t

68 Deletion analysis of the sigmaNS RNA binding domain and G3BP1 RNA (RRM) and ribosomal (RG

69 The TERT RNA binding domain and N-terminal RNA interaction domain

70 valent interactions with the double stranded RNA binding domain and the basic region underlie the abi

71 he individually determined structures of the RNA binding domain and the effector domain from non-H5N1

72 istance distribution functions of the U2AF65 RNA binding domain and those either previously observed

73 ition of the small RNA substrate by multiple RNA binding domains and the methyltransferase domain in

74 The proteins have three RNA binding domains and two glycine-rich domains and loc

75 The US11 RNA-binding domain and < or =46 bases of selected RNA co

76 threonine kinase that contains an N-terminal RNA-binding domain and a C-terminal kinase domain.

77 ecific inhibition of translation through its RNA-binding domain and a region in the C-terminal domain

78 NS1 has two domains, an RNA-binding domain and an effector domain separated by a

79 lanogaster demonstrates how a well-conserved RNA-binding domain and cognate binding sequence have bee

80 An intact K homology domain 2 (KH2) RNA-binding domain and dephosphorylation of FMRP at S500

81 xport of M1 mRNA required both an intact NS1 RNA-binding domain and effector domain.

82 DLC-1 directly binds to FBF-2 outside of the RNA-binding domain and promotes FBF-2 localization and f

83 and contained nucleolar localization signal, RNA-binding domain and several phosphorylation sites.

84 d by RNA-binding proteins that consist of an RNA-binding domain and two reiterated phosphotransferase

85 6 shares a domain structure containing three RNA-binding domains and a divergent domain of unknown fu

86 It possesses three RNA-binding domains and is involved in the regulation of

87 losses and acquisitions of diverse putative RNA-binding domains and the acquisition of an Archaea-li

88 erminal region of the protein that lacks the RNA-binding domains and uridyltransferase activity of th

89 The SFPQ*NONO complex contains an RNA binding domain, and prior work has demonstrated dive

90 ction are homodimerization of its kinase and RNA-binding domains, and autophosphorylation at the resi

91 ng antiviral properties of this protein, the RNA-binding domains, and the minimal effects observed on

92 cture, with both zinc knuckle and cold shock RNA-binding domains, and were originally identified as r

93 other topoisomerases, contains a distinctive RNA-binding domain; and deletion of this domain diminish

94 nd that several arginines within the TAP and RNA binding domains are methylated in vivo.

95 Highly conserved amino acids of the duplex RNA-binding domain are required for processivity and nuc

96 he distal alpha-helix of the double-stranded RNA-binding domains are necessary to engage structural f

97 MBNL1 contains four zinc finger (ZF) RNA binding domains arranged in two pairs.

98 (AUAUAU) are specifically recognised by two RNA-binding domains arranged in tandem.

99 virions we identified the second of the two RNA-binding domains as a principal determinant of MHV pa

100 oteins within these bodies contain KH or RRM RNA-binding domains as well as low complexity (LC) seque

101 terferon-responsible promoter, has a Z-DNA/Z-RNA binding domain at its N-terminus.

102 analysis indicates that the two double stand RNA binding domains at the N-terminus of RHA are respons

103 o alpha-beta-beta-beta-alpha double-stranded RNA-binding domains at the N terminus and repeated argin

104 ated targets for a protein without canonical RNA-binding domains, Bfr1p.

105 minimal RNA fragment that are key to Nup153 RNA-binding domain binding and demonstrated that the bin

106 Its N-terminal RNA-binding domain binds dsRNA.

107 estigated by NMR the dynamics of the CstF-64 RNA-binding domain, both free and bound to two GU-rich R

108 ristics, the X-ray structure of the U2AF(65) RNA binding domain bound to a Py tract composed of seven

109 ined four structures of an extended U2AF(65)-RNA-binding domain bound to Py-tract oligonucleotides at

110 RSF1 deletion mutants containing the protein RNA-binding domains but not the arginine serine-rich act

111 tructure, including the presence of putative RNA-binding domains, but to what extent they provide fun

112 family of RNA-binding proteins share similar RNA-binding domains by which they regulate the translati

113 in Dim2, providing another example where an RNA-binding domain can be repurposed for protein interac

114 In particular, the catalytic domain and the RNA-binding domain can move around a central hinge.

115 substrate and that removal of its KH and S1 RNA-binding domains can reduce enzyme processivity witho

116 Both the N-terminal domain (containing an RNA-binding domain characterized by the presence of five

117 ons, we detected a divergent double-stranded RNA-binding domain coinciding with the DUF283 of Dicer.

118 Three RNA-binding domains come together to form a clamp-like a

119 ally to mRNA targets using a single-stranded RNA-binding domain comprising eight Pumilio (PUM) repeat

120 e mRNA led to the conclusion that the Nup153 RNA binding domain confers a general affinity for single

121 Furthermore, we identified SON, a DNA/RNA-binding domain containing protein, as a novel NHR4-i

122 Here, we have used analogues of the TTP RNA-binding domain containing specific tryptophan substi

123 rotein contains two structurally independent RNA binding domains, designated the N-terminal domain (N

124 ere, the solution conformation of the U2AF65 RNA binding domain determined using small angle x-ray sc

125 RNA intermediate, and mutations in the pTRS1 RNA binding domain did not affect PKR binding or inhibit

126 located in a conserved TPNK sequence in the RNA binding domain, did not restore viability and histon

127 RNA translation or disrupting coat protein's RNA binding domain diminished replication.

128 RNA recognition to decipher how this unique RNA binding domain discriminates between potential targe

129 es, both of which required a double-stranded RNA-binding domain (dsRBD) and a functional helicase mot

130 specific interactions by its double-stranded RNA-binding domain (dsRBD) helix alpha1 to the tetraloop

131 odular enzymes with multiple double-stranded RNA binding domains (dsRBDs) and a catalytic domain.

132 The proteins harboring double-stranded RNA binding domains (dsRBDs) play diverse functional rol

133 Double-stranded RNA-binding domains (dsRBDs) are commonly found in modul

134 specific protein TRBP, whose double-stranded RNA-binding domains (dsRBDs) interact with the A-form ge

135 affinities of dsRNAs to PKR double-stranded RNA-binding domains (dsRBDs) were determined by isotherm

136 sts of proteins that possess double-stranded RNA-binding domains (dsRBDs).

137 LS) that overlaps one of its double-stranded RNA-binding domains (dsRBDs).

138 associates with E3 ubiquitin ligases bearing RNA-binding domains, Dzip3 and Mex3b, as well as with th

139 d to the way in which proteins with multiple RNA binding domains engage with target RNAs.

140 osophila CPEB functions independently of its RNA-binding domain for memory.

141 Three RNA-binding domains form an open funnel on one face of t

142 The CRM domain is a recently recognized RNA binding domain found in three group II intron splici

143 rming canonical eight-repeat crescent-shaped RNA-binding domains found in classical PUF proteins.

144 interactions are mapped to two, independent, RNA-binding domains from RNase E.

145 Proteins containing the STAR RNA-binding domain fulfill vital roles in RNA biogenesis

146 library of eight aptamers and corresponding RNA binding domains fused to partial fragments of fluore

147 Expression of FMRP lacking the RGG box RNA-binding domain had no effect on AMPAR levels.

148 y, whereas R84Q or V154S substitution in the RNA binding domain has no effect.

149 w of an important member of the RRM class of RNA-binding domains highlights the role of alternative s

150 structure of a ternary complex of human SLBP RNA binding domain, human 3'hExo, and a 26-nucleotide SL

151 RGG/RG domains are the second most common RNA binding domain in the human genome, yet their RNA-bi

152 polymerase (RNAP) beta subunit is a part of RNA binding domain in transcription complex.

153 The C-proximal motif within the N-terminal RNA binding domain in wheat eIF4B is required for intera

154 ins are the largest class of single-stranded RNA binding domains in the human proteome and play impor

155 recognition motif (RRM) is the most abundant RNA-binding domain in eukaryotes, and it plays versatile

156 rus expressing an NS1A protein containing an RNA-binding domain in which R38 is mutated to A.

157 e ASCH superfamily are likely to function as RNA-binding domains in contexts related to coactivation,

158 Our results demonstrate that the RNA binding domain is a critical regulator of both cytok

159 The PSP-1 RNA binding domain is required for its colocalization wi

160 c analyses revealed that the single-stranded RNA-binding domain is exclusively found in Prp3 ortholog

161 genes and that the thyroid hormone receptor RNA-binding domain is important for this enhancement.

162 e protein to p62/SQSTM1, suggesting that the RNA-binding domain is responsible for the subcellular lo

163 ion provided by the regions flanking the PUF RNA-binding domain is unknown.

164 TENR contains a double-stranded RNA binding domain, is localized to the nucleus, and is

165 c finger domain, which is the protein's main RNA binding domain, is most important for SG recruitment

166 tein), which contains three double-stranded, RNA-binding domains, is an integral component of a Dicer

167 e domain of RNase R, devoid of all canonical RNA-binding domains, is sufficient for this activity.

168 antages over classic methods for determining RNA-binding domains: it produces proteome-wide, high-res

169 NCL RNA-binding domain K429 was critical for ATP and EBNA1 b

170 two zinc knuckles and between the N-terminal RNA binding domains (KH and QUA2 domains) and the first

171 ine the roles of selected amino acids in the RNA binding domain, known as the tandem zinc finger (TZF

172 ge benchmark of 212 RNA binding and 6761 non-RNA binding domains (leave-one-out cross-validation).

173 t stem loop of kor mRNA 5'-UTR through a new RNA-binding domain located in its amino terminus.

174 hile intensity of the CLIP signal, number of RNA-Binding domains, location of the binding site on the

175 re domain of eIF4G plus an adjacent probable RNA-binding domain mediate translation initiation.

176 nds were known functional domains (e.g., DNA/RNA-binding domains), most were uncharacterized.

177 ndent termination functions of specific NusA-RNA binding domain mutants revealed an existence of Rho-

178 xpression through the function of an unusual RNA-binding domain named RAP (for RNA-binding domain abu

179 data, we were able to construct an isolated RNA-binding domain (Nop-RBD) that folds correctly as dem

180 LARP6 has a distinctive bipartite RNA binding domain not found in other members of the La

181 er, is abolished by a mutation either in the RNA binding domain of 3CD(pro), 3C(pro)R84S/I86A, or by

182 step toward RNA recognition, we utilized the RNA binding domain of argonaute, implicated in RNA inter

183 The RNA binding domain of heterogeneous nuclear ribonucleopr

184 The C- terminal KH3 domain but not the RNA binding domain of ICP27 is required for its specific

185 functional integrity of the highly conserved RNA binding domain of NS1.

186 Minicores lack significant portions of the RNA binding domain of p21 core.

187 fection, focusing on the contribution of the RNA binding domain of the NS1 protein.

188 A genetically encoded system based on the RNA binding domain of the Pumilio and FBF (PUF) proteins

189 pecific high-affinity interaction between an RNA binding domain of trimeric N and the panhandle is re

190 our results reveal that the N-terminal Z-DNA/RNA binding domain of vaccinia virulence factor E3, whic

191 te of GRIA2 Furthermore, the double-stranded RNA binding domains of ADAR3 are required for repression

192 Our data suggest that the RNA binding domains of eIF4G provide the S. cerevisiae e

193 sid (N) protein that harbors two independent RNA binding domains of known structure, but poorly chara

194 somal particles requires the double-stranded RNA binding domains of NF90, while depletion of NF45 and

195 The first two RNA binding domains of nucleolin were sufficient for hig

196 Furthermore, we showed that the RNA binding domains of Su(s) are important for this effe

197 We test the method on the RNA binding domains of three important regulators of RNA

198 ainst antigenic peptides residing within the RNA-binding domain of 70 kDa.

199 by mutation of a key residue in the putative RNA-binding domain of AID impairs recruitment of AID to

200 e discovery of a cyclic peptide mimic of the RNA-binding domain of BIV Tat protein based on a designe

201 This activity is dependent on the RNA-binding domain of Boule and a conserved DAZ (deleted

202 longin-binding domain of VHL with a specific RNA-binding domain of HuR (RRM1) is important for the de

203 Here, we present crystal structures of the RNA-binding domain of Lassa virus NP in complex with ssR

204 de-acridine conjugates using portions of the RNA-binding domain of N protein (11- and 22- residue pep

205 We found that the RNA-binding domain of NCL participates in binding to p53

206 nce coding regions and is facilitated by the RNA-binding domain of NS1, which can associate with ER m

207 The minimal RNA-binding domain of NS5A consists of residues 2005 to

208 The RNA-binding domain of PUF proteins typically consists of

209 The conserved RNA-binding domain of Pumilio was thought to be sufficie

210 we report the crystal structure of the DNA-/RNA-binding domain of Pur-alpha in complex with ssDNA.

211 ce of the binding of oligonucleotides to the RNA-binding domain of Rho protein (rho130).

212 Point mutations in the S1 RNA-binding domain of RNase E (rne-1 and rne-3071) lead

213 panied by phylum-specific alterations in the RNA-binding domain of Srp54, the SRP protein subunit tha

214 cally dependent on the third double-stranded RNA-binding domain of Staufen1 and shuttling of Staufen1

215 result re-establishes the RRM as the primary RNA-binding domain of the hnRNP C tetramer and provides

216 A with an affinity comparable to that of the RNA-binding domain of the Tat protein and inhibited prot

217 ACT and TRBP suggest that the two N-terminal RNA-binding domains of each protein confer the observed

218 ments that correspond to the two independent RNA-binding domains of FMRP, in addition to the binding

219 mine whether the observed variability in the RNA-binding domains of four plant PUFs results in a pref

220 icing factors by combining sequence-specific RNA-binding domains of human Pumilio1 with functional do

221 UMP domain, which appears to be unrelated to RNA-binding domains of known structure.

222 tion of N was shown to depend on both of the RNA-binding domains of N, as well as on the serine- and

223 cherichia coli, we identified two additional RNA-binding domains of nsp3.

224 n calorimetry experiments confirmed that the RNA-binding domains of PKR are sufficient and necessary

225 nsion also enables the identification of the RNA-binding domains of RBPs.

226 s work describes the interactions of the two RNA-binding domains of the nucleocapsid protein of a mod

227 port the hypothesis that the double-stranded RNA-binding domains of this family of proteins are impor

228 t the altered amino acids are located in the RNA-binding domains of two complex THOC2 structures, pot

229 ding of dsRNA to two dsRBDs (double-stranded RNA binding domains) of PKR modulates its own kinase act

230 The presence of putative RNA-binding domains on the Rpb7 subunit and the position

231 Plant eIF4B contains three RNA binding domains, one more than reported for mammalia

232 nding proteins (RBPs): i.e. those with known RNA binding domains or otherwise implicated in RNA funct

233 oreover, Top3beta mutants lacking either its RNA-binding domain or catalytic residue fail to promote

234 unctional category 'RNA-binding', have known RNA-binding domains or have orthologs identified in mamm

235 etry, we have identified the double-stranded RNA-binding domain protein Blanks to be an siRNA- and ds

236 ear RNase III Drosha and the double-stranded RNA-binding domain protein DGCR8 (DiGeorge syndrome crit

237 peptide transduction domain-double-stranded RNA-binding domain (PTD-DRBD) fusion protein.

238 SRp38 contains an N-terminal RNA binding domain (RBD) and a C-terminal RS domain comp

239 terogenous ribonucleoprotein A18 (hnRNP A18) RNA Binding Domain (RBD) and the arginine, glycine (RGG)

240 mplex between a fragment of 23S rRNA and the RNA binding domain (RBD) of the Bacillus subtilis DbpA p

241 Previous studies have identified an RNA binding domain (RBD) within TERT, which includes thr

242 To further define the boundaries of the RNA binding domain (RBD), several peptides were synthesi

243 d that hnRNPC binds to uPAR mRNA through its RNA binding domain (RBD).

244 TDP-43 possesses two RNA binding domains (RBD) and a glycine-rich C terminus

245 nal protein with two distinctive domains, an RNA-binding domain (RBD) and an effector domain (ED) sep

246 ry site/segment (IRES)-the question of which RNA-binding domain (RBD) binds to which sites on the IRE

247 ues from both chains, namely residues in the RNA-binding domain (RBD) from one chain, and residues in

248 Here, we show that the RNA-binding domain (RBD) of SRSF1 optimally binds to dec

249 tical lysine residue (K41) in the N-terminal RNA-binding domain (RBD).

250 PSF also contains two RNA-binding domains (RBD) that form a complex with a non

251 6 A in the free RNA, to 58 A when N-terminal RNA binding domains (RBD1) of U1A are bound, and to 53 A

252 In addition, OV20.0 binds directly to the RNA binding domains (RBDs) of PKR, and this interaction

253 hibitory interactions between the kinase and RNA binding domains (RBDs), but the structural details o

254 biology, containing a diversity of canonical RNA binding domains (RBDs).

255 It has four RNA-binding domains (RBDs), but although the contacts wi

256 l region of the protein contains four tandem RNA-binding domains (RBDs), of which the first two are r

257 hin 529 HeLa cell RBPs, discovering numerous RNA-binding domains (RBDs).

258 Moreover, each RNA binding domain requires dimerization for binding act

259 ical separation of the Sec incorporation and RNA-binding domains revealed that they are able to funct

260 ut fungi, with divergent and distinctive PUF RNA binding domains, RNA-recognition motifs (RRMs), and

261 CELF proteins contain two adjacent RNA binding domains (RRM1 and RRM2) near the N-terminus

262 ft assays using a bacterially expressed PUM2 RNA binding domain showed specific binding using wild ty

263 The NMR structure of its RNA-binding domain shows two unusually compact RNA recog

264 creased the activity of the eIF4B C-terminal RNA-binding domain specifically.

265 Solving the RNA-binding domain structures revealed the canonical NS1

266 N-terminal Nab2 domain is distinct from its RNA binding domains suggesting Nab2 could bind Gfd1 and

267 86% success rate in its application to SCOP RNA binding domain superfamily (Structural Classificatio

268 lity shift assays using the recombinant TEP1 RNA-binding domain (TEP1-RBD) demonstrate that it binds

269 cognition specificity and define a novel p65 RNA binding domain that initiates telomerase holoenyzme

270 ' end of the exon specify FMRP's RGG box, an RNA binding domain that interacts with G-quartet motifs.

271 ricopeptide repeat (PPR) proteins include an RNA binding domain that provides site specificity.

272 ain, wheat eIF4B contains a novel N-terminal RNA binding domain that requires a short, lysine-rich co

273 trolled Mre11 abundance through a C-terminal RNA binding domain that selectively and directly binds M

274 idine Tract Binding Protein (PTBP1) has four RNA binding domains that each binds a short pyrimidine e

275 example to the repertoire of plant-specific RNA binding domains that emerged as a product of nuclear

276 ified and mutated several residues in the S1 RNA-binding domain that are important for interacting wi

277 ivity are mediated by sequences flanking the RNA-binding domain that bind specific molecular partners

278 ontains the PUA domain, a recently described RNA-binding domain that is found in several tRNA and rRN

279 in with a THUMP domain, an ancient predicted RNA-binding domain that is widespread in all kingdoms of

280 Mutations in the RNA-binding domains that inhibit RNA binding also affect

281 NF90 has additional double-stranded RNA-binding domains that likely mediate its association

282 ine in a conserved TPNK sequence in the SLBP RNA binding domain, thereby dissociating SLBP from the h

283 dopsis Fip1 protein were found to contain an RNA-binding domain; this domain correlated with an intac

284 izes different surfaces of its alpha-helical RNA-binding domain to recognize several low-affinity bin

285 be processive enzymes by attaching a duplex RNA-binding domain to the RNase H region.

286 binding protein that harbors three canonical RNA-binding domains, two KH-type and one RGG box.

287 ncanonical poly(A) polymerase that lacks the RNA-binding domain typical of the canonical nuclear poly

288 hereas a deletion mutant containing only the RNA binding domains was devoid of activity.

289 (MHV), we constructed mutants in which each RNA-binding domain was replaced by its counterpart from

290 and RNA interactions of the wild-type U2AF65 RNA binding domain were compared with those of U2AF65 va

291 EBNA1's N-terminal 100 aa and NCL's RNA-binding domains were critical for EBNA1/NCL interact

292 erved RNA recognition motif and a C-terminal RNA binding domain, wheat eIF4B contains a novel N-termi

293 PKR contains an N-terminal double-stranded RNA binding domain, which consists of two tandem double-

294 lian and viral mRNAs also interact with this RNA-binding domain with functional consequences to their

295 on, it correctly identified 31 of 75 unbound RNA-binding domains with 92% accuracy and 65% precision

296 e effector domain from non-H5N1 strains, the RNA binding domain within H5N1 NS1 exhibits modest struc

297 Mutations in the predicted RNA binding domains within PES4 alter the stability of t

298 We identified a RNA-binding domain within the C-terminus of RbgA that is

299 nstrate that its three previously elucidated RNA binding domains work together to provide eIF4F with

300 ch extends over a distance of 180 A from its RNA binding domain, wraps around the core domain consist