ライフサイエンスコーパス: RNA-dependent protein kinase

1 y modulating the activity of double-stranded RNA-dependent protein kinase.

2 se R-motif exons of the interferon-inducible RNA-dependent protein kinase.

3 veal the existence in nuclear extracts of an RNA-dependent protein kinase activity that hyperphosphor

4 S, was dependent on CD14 activity but not on RNA-dependent protein kinase and could be inhibited by a

5 igoadenylate synthetase, and double-stranded-RNA-dependent protein kinase as well as those coding for

6 investigated the role of the double-stranded RNA-dependent protein kinase gene (pkr) in the regulatio

7 feron-alpha --> upward arrow double-stranded RNA-dependent protein kinase --> downward arrow c-Myc --

8 eta mRNA was MyD88- and PKR (double-stranded RNA-dependent protein kinase)-independent, but TIRAP (To

9 n [IFN-beta], IFN-gamma, protein Mx1 GTPase, RNA-dependent protein kinase, inducible nitric oxide syn

10 PKR (double-stranded RNA-dependent protein kinase) is an important component

11 , so we monitored the activity of PERK [PKR (RNA-dependent protein kinase)-like ER kinase (EIF2AK3)],

12 c translation initiator factor 2alpha kinase RNA-dependent protein kinase-like ER kinase (PERK) allow

13 tx1 activated the proximal ER stress sensors RNA-dependent protein kinase-like ER kinase and inositol

14 led by the activation of ER stress-inducible RNA-dependent protein kinase-like ER-integral (PERK) eIF

15 e anti-viral response, e.g., double-stranded RNA-dependent protein kinase, myxovirus resistance prote

16 a and IL-18 - as well as the double-stranded-RNA-dependent protein kinase pathway and RNaseL pathway,

17 nd inhibit activation of the double-stranded RNA-dependent protein kinase PKR in cell-free systems, a

18 RNA-dependent protein kinase PKR is an important regulat

19 The double-stranded (ds) RNA-dependent protein kinase PKR is considered to play a

20 The interferon-induced RNA-dependent protein kinase PKR is found in cells in a

21 d autophosphorylation of the double-stranded RNA-dependent protein kinase PKR leading to phosphorylat

22 nterestingly, absence of the double-stranded RNA-dependent protein kinase PKR led to a profound defec

23 d to be effective in blocking binding to the RNA-dependent protein kinase PKR, a cytoplasmic dsRNA-bi

24 t a major effector of the C phenotype is the RNA-dependent protein kinase PKR.

25 ith the pathway regulated by double-stranded RNA-dependent protein kinase PKR.

26 rotein synthesis mediated by double-stranded-RNA-dependent protein kinase PKR.

27 in synthesis mediated by the double-stranded-RNA-dependent protein kinase PKR.

28 is study quantified constitutive and induced RNA-dependent protein kinase (PKR) activation in Fanconi

29 gamma, and the activation of double-stranded RNA-dependent protein kinase (PKR) and eukaryotic initia

30 Phosphorylation of double-stranded RNA-dependent protein kinase (PKR) and eukaryotic initia

31 through the increase of the double-stranded RNA-dependent protein kinase (PKR) and following inactiv

32 olyinosinic-polycytidylic acid activated the RNA-dependent protein kinase (PKR) and induced significa

33 specific adenosine deaminase (ADAR1) and the RNA-dependent protein kinase (PKR) are both interferon-i

34 RNase L and RNA-dependent protein kinase (PKR) are effectors of the

35 virus 1 (HSV-1) results in the activation of RNA-dependent protein kinase (PKR) but that the alpha su

36 tranded RNA, which activates double-stranded RNA-dependent protein kinase (PKR) by mimicking viral in

37 re, we provide evidence that double-stranded RNA-dependent protein kinase (PKR) can respond to nutrie

38 The depletion of double-stranded RNA-dependent protein kinase (PKR) from these MEFs resto

39 study, the role of the double-stranded (ds) RNA-dependent protein kinase (PKR) in macrophage activat

40 repressed expression of the double-stranded RNA-dependent protein kinase (PKR) in the promonocytic U

41 Double stranded RNA-dependent protein kinase (PKR) is a double stranded

42 The double-stranded (ds) RNA-dependent protein kinase (PKR) is a primary regulato

43 h herpes simplex virus 1 the double-stranded RNA-dependent protein kinase (PKR) is activated but phos

44 The RNA-dependent protein kinase (PKR) is activated by bindi

45 Although the double-stranded RNA-dependent protein kinase (PKR) is activated during H

46 The human double-stranded RNA-dependent protein kinase (PKR) is an important compo

47 The RNA-dependent protein kinase (PKR) is an interferon-indu

48 The RNA-dependent protein kinase (PKR) is an interferon-indu

49 The RNA-dependent protein kinase (PKR) is an interferon-indu

50 RNA-dependent protein kinase (PKR) is an interferon-indu

51 ed upon virus infection, the double-stranded RNA-dependent protein kinase (PKR) is best known for tri

52 The RNA-dependent protein kinase (PKR) is implicated in the

53 situation and show that the double-stranded RNA-dependent protein kinase (PKR) is involved in the lo

54 we provide evidence that the double-stranded RNA-dependent protein kinase (PKR) is not required for v

55 The RNA-dependent protein kinase (PKR) is regulated by the b

56 s in which the activation of double-stranded RNA-dependent protein kinase (PKR) is suppressed.

57 red that viperin, ISG20, and double-stranded RNA-dependent protein kinase (PKR) noncytolytically inhi

58 The RNA-dependent protein kinase (PKR) plays an integral rol

59 The double-stranded (ds) RNA-dependent protein kinase (PKR) regulates protein syn

60 e interferon-inducible, double-stranded (ds) RNA-dependent protein kinase (PKR) regulates protein syn

61 N-terminal kinase (JNK) and double-stranded RNA-dependent protein kinase (PKR) to induce autophagy w

62 The gene encoding the interferon-inducible, RNA-dependent protein kinase (PKR) was isolated as lambd

63 Double-stranded RNA-dependent protein kinase (PKR), a ubiquitously expre

64 promotes the degradation of double-stranded RNA-dependent protein kinase (PKR), and it suppresses ho

65 d in an elevation in an IFN-responsive gene, RNA-dependent protein kinase (PKR), but not 2',5'-oligoa

66 the human eIF2alpha kinase, double-stranded-RNA-dependent protein kinase (PKR), impeded growth of S.

67 e proteasomal degradation of double-stranded RNA-dependent protein kinase (PKR), little is known abou

68 eIF-2alpha kinases including double-stranded RNA-dependent protein kinase (PKR), which has been recen

69 da7 induces andactivates the double-stranded RNA-dependent protein kinase (PKR), which leads to phosp

70 itro transcripts containing uridine activate RNA-dependent protein kinase (PKR), which then phosphory

71 the role of the ER resident protein kinase, RNA-dependent protein kinase (PKR)-like ER kinase (PERK)

72 ured cells due to their inability to prevent RNA-dependent protein kinase (PKR)-mediated inhibition o

73 ansgenic mouse strain in which double-strand RNA-dependent protein kinase (PKR)-mediated phosphorylat

74 on through activation of the double-stranded RNA-dependent protein kinase (PKR).

75 is mediated by activation of double-stranded RNA-dependent protein kinase (PKR).

76 protein synthesis involving double-stranded RNA-dependent protein kinase (PKR).

77 tor of P58(IPK), a cellular inhibitor of the RNA-dependent protein kinase (PKR).

78 optotic interferon-inducible double-stranded RNA-dependent protein kinase (PKR).

79 ation, suggesting a role for double-stranded RNA-dependent protein kinase (PKR).

80 slational arrest mediated by double-stranded-RNA-dependent protein kinase (PKR).

81 alpha by up-regulating the expression of the RNA-dependent protein kinase (PKR).

82 here we identify a role for double-stranded RNA-dependent protein kinase (PKR, also known as EIF2AK2

83 RNA-specific adenosine deaminase [ADAR1] and RNA-dependent protein kinase [PKR]) in a tissue-specific

84 rt that in HeLa cells, activation of a PERK (RNA-dependent protein kinase [PKR]-like ER kinase)-eIF2a

85 in vitro with and inhibits the IFN-induced, RNA-dependent protein kinase, PKR, and that NS5A interac

86 The antiviral RNA-dependent protein kinase, PKR, binds to viral double

87 plication indicated that the double-stranded RNA-dependent protein kinase, PKR, exerted some early an

88 -terminal region of the double-stranded (ds) RNA-dependent protein kinase, PKR, has been shown to med

89 is now apparent that the double-stranded (ds)RNA-dependent protein kinase, PKR, is a regulator of div

90 have shown recently that the double-stranded RNA-dependent protein kinase, PKR, is involved in transl

91 ctor 2 (eIF2alpha) by the interferon-induced RNA-dependent protein kinase, PKR, leads to inhibition o

92 y by the interferon-induced, double-stranded RNA-dependent protein kinase, PKR.

93 tRNA2-1 and down-regulate the phosphorylated RNA-dependent protein kinase (pPKR), whose activity has

94 ulated gene products such as double-stranded RNA-dependent protein kinase R (PKR), 2',5'-oligoadenyla

95 nctions of the IFN-inducible double-stranded RNA-dependent protein kinase R or PKR.

96 anslation arrest mediated by double-stranded RNA-dependent protein kinase R.

97 t restored in the absence of double-stranded RNA-dependent protein kinase, RNase L, or IFN-alpha/beta

98 pkr gene encoding the interferon-inducible, RNA-dependent protein kinase was isolated as lambda phag

99 The double-stranded RNA-dependent protein kinase was not essential for DC ma

100 PKR is a doubled-stranded RNA-dependent protein kinase which is implicated in the