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1 RNA binding motif protein 25 (RBM25) is a putative splic
2 RNA editing is an essential post-transcriptional process
3 RNA interference (RNAi) is known for its high catalytic
4 RNA interference suppression of NaSIPP in Nicotiana spp.
5 RNA molecules cause the proteins involved in the formati
6 RNA polymerase and ribosomes form a one-to-one complex w
7 RNA quality was also assessed.
8 RNA sequencing analysis was performed and 263 genes were
9 RNA sequencing confirmed that Hh-mediated transcription
10 RNA-binding proteins of the Musashi (Msi) have been impl
11 RNA-mediated interference has been one major approach fo
12 RNA-protein interactions are essential for proper gene e
13 RNA-seq analysis demonstrates differential gene expressi
14 RNA-seq analysis detected aberrant splicing in DONSON du
15 RNA-seq analysis of whole skin identified a larger numbe
16 RNA-seq and RT-qPCR identified potential downstream gene
19 h less than 50 copies per mL of plasma HIV-1 RNA at week 48 (by the US Food and Drug Administration s
21 Using a single-copy assay, we measured HIV-1 RNA levels in CSF and plasma specimens from 220 HIV-posi
22 virological suppression (<50 copies of HIV-1 RNA per mL) on a stable regimen for at least 6 months, C
23 of known and putative SSP genes based on 144 RNA sequencing data sets covering various stages of macr
27 iologic role of N(6)-methyladenosine (m(6)A) RNA modifications in mRNA requires an understanding of w
30 uding RNA structure analysis, RNA alignment, RNA annotation, RNA-protein interaction, ribosome profil
34 ific mouse reporter strains, we performed an RNA-seq screen, identifying tip- and stalk-enriched gene
36 NA biology including RNA structure analysis, RNA alignment, RNA annotation, RNA-protein interaction,
41 Here, we used shotgun proteomics, OxICAT and RNA-seq transcriptomics to analyse protein S-mycothiolat
42 gene circuits that combine DNA, protein, and RNA components have demonstrated a range of functions su
43 combined methods of genetics, proteomics and RNA biochemistry, we identified a core set of mRNA m(6)
45 ultiple neurite-targeted non-coding RNAs and RNA-binding proteins with potential regulatory roles.
46 atin immunoprecipitation with sequencing and RNA sequencing, we identify a novel B-lymphoid program f
47 a unique set of non-coding transcripts, and RNAs present at active centromeres are necessary for kin
48 characterization of previously un-annotated RNA transcripts expressed by the spirochete during murin
49 ure analysis, RNA alignment, RNA annotation, RNA-protein interaction, ribosome profiling, RNA-seq ana
51 t study, we test this hypothesis by applying RNA sequencing to CD4(+), CD8(+), and CD19(+) lymphocyte
53 rlies all secondary genomic analyses such as RNA sequencing (RNA-Seq), chromatin immunoprecipitation,
55 luding metabolism and cell cycle, as well as RNA- and protein-modifying enzymes that functionally div
57 technology is to ligate chromatin-associated RNAs (caRNAs) with their target genomic sequences by pro
61 r topoisomerase for mRNAs, and requires both RNA binding and catalytic activity to promote neurodevel
62 ic variability is evident between clones, by RNA-sequencing, and at the single-cell level, by RNA-FIS
63 Functional consequences were investigated by RNA studies and on the cellular level using immunofluore
64 sequencing, and at the single-cell level, by RNA-FISH, and is not attributable to differences in repr
67 nscriptomes of individual cells, single-cell RNA sequencing provides unparalleled resolution to study
68 ombine novel mouse reporters and single-cell RNA sequencing to reveal the heterogeneity in IL-4-induc
70 nd their microenvironments using single-cell RNA-seq from 11 primary colorectal tumors and matched no
72 (2017) demonstrate that endogenous circular RNAs may generate proteins, thereby expanding the eukary
73 gically, the steady-state levels of circular RNAs increased while expression of their associated line
74 as the functions of enhancer RNAs, circular RNAs and chemical modifications to RNA in cellular proce
76 zation of a novel long intergenic non-coding RNA with MyoD-regulated and skeletal muscle-restricted e
77 dentify multiple neurite-targeted non-coding RNAs and RNA-binding proteins with potential regulatory
79 cleotide germ line-specific small non-coding RNAs that have evolutionarily conserved function in mobi
80 MicroRNAs (miRNAs) are small, non-coding RNAs that play critical roles in the post-transcriptiona
81 ly important but not yet standard to combine RNA-centric data and analysis tools with other types of
83 he unbiased characterization of the complete RNA cargo, including both small- and long-RNAs, in a sin
85 Neuronal protein 3.1 (P311), a conserved RNA-binding protein, represents the first documented pro
89 gests that localization of the APC-dependent RNA subgroup is functionally important for cell migratio
90 ch to specifically mislocalize APC-dependent RNAs suggests that localization of the APC-dependent RNA
91 uencing (RNAseq), we found that host-derived RNAs, most prominently 5S ribosomal RNA pseudogene 141 (
93 of using a single receptor target to develop RNA aptamers with dual activity for effectively blocking
94 hat recognizes U/AU-rich elements in diverse RNAs through two RNA-recognition motifs, RRM1 and RRM2,
96 izes RNA-functionalized AuNPs which form DNA-RNA heteroduplex structures through specific hybridizati
99 A biology, such as the functions of enhancer RNAs, circular RNAs and chemical modifications to RNA in
103 q, differential gene expression analysis for RNA-seq, nucleosome positioning for MNase-seq, DNase hyp
105 uorescence complementation (AiFC) method for RNA imaging by engineering a green fluorescence protein
106 cleavage is a likely point of regulation for RNA editing, we elucidated endonuclease specificity in v
107 ntified transcriptome-wide binding sites for RNA polymerase II and the exosome cofactors Mtr4 (TRAMP
110 mic sequences by proximity ligation, forming RNA-DNA chimeric sequences, which are converted to a seq
111 jects, GXD collects and integrates data from RNA in situ hybridization, immunohistochemistry, RT-PCR,
112 ing differentially expressed (DE) genes from RNA sequencing (RNAseq) studies is among the most common
113 irst time the dynamic connection between FTO RNA binding and demethylation activity that influences s
120 downstream analysis of large, heterogeneous RNA-Seq data sets and we demonstrate its use with data f
125 aviremic for 7.4 months, rebounding with HIV RNA of 36 copies/mL that rose to 59,805 copies/mL 6 days
126 ate local human immunodeficiency virus (HIV) RNA levels and the risk of sexual HIV transmission.
128 We describe opportunities and challenges in RNA structural modeling and design, as recently discusse
129 ruses, and papillomaviruses were detected in RNA-seq data, but proportions were similar (P = .73) acr
130 site dT, predicting frequent A-->G errors in RNA with rates of approximately 10(-4) The A-->C, G-->A,
131 important roles of co-opted host proteins in RNA virus replication have been appreciated for a decade
134 rent research areas of RNA biology including RNA structure analysis, RNA alignment, RNA annotation, R
135 ector portion of the RdDM pathway, including RNA POLYMERASE V (POL V), DOMAINS REARRANGED METHYLTRANS
137 s accumulation of untrimmed piwi-interacting RNA intermediates with 3' end extension, leading to seve
138 1 mutation in mice inhibits piwi-interacting RNA trimming and causes accumulation of untrimmed piwi-i
141 Transfection of Sirtuin-1 small interfering RNA prevented hnRNP F stimulation of Foxo3alpha and down
142 ility complex molecules by small interfering RNA targeting of class II transactivator can reduce the
144 anti-inflammatory drugs or small interfering RNAs (siRNAs) against COX-1 and COX-2, significantly red
145 ANCI (Nkx2.1-associated noncoding intergenic RNA)-Nkx2.1 gene duplex that is essential for buffering
146 ression of coding, noncoding, and intergenic RNAs in the mature mouse brain with RNA-Seq and validati
147 yladenosine (m(6)A) is an essential internal RNA modification that is critical for gene expression co
148 A receptor target (i.e. GluA1/2R) to isolate RNA aptamers that can potentially inhibit both AMPA and
149 roteins, nearly all essential domains of its RNA, and five stably associated auxiliary proteins.
152 down-regulation of P311 levels by lentiviral RNA interference reproduced the deficits seen in P311(-/
155 llectively, these data reveal that mammalian RNAs can harbor a 5' end modification distinct from the
156 in the 5'-untranslated regions of messenger RNA requires the temporal synchronization of RNA synthes
158 eric block ASO that binds the SMN2 messenger RNA and promotes exon 7 inclusion and thus increases ful
159 ive expression levels of four host messenger RNAs, was developed to discriminate critically ill adult
160 Safe and efficient delivery of messenger RNAs for protein replacement therapies offers great prom
166 te that L alone initiates synthesis on naked RNA and that P serves to enhance the initiation and proc
167 effector complexes to complementary nascent RNAs to initiate histone H3 lysine 9 di- and trimethylat
168 located in the intron of the long noncoding RNA (lncRNA) LINC00305 by searching the GWAS database.
174 dences have demonstrated that long noncoding RNAs (lncRNAs) play important roles in many human diseas
175 ally, sRNAs, originating from long noncoding RNAs, guide Argonaute-containing effector complexes to c
176 A bases are not only found in many noncoding RNAs but have also recently been identified in coding (m
177 The discovery of thousands of noncoding RNAs (ncRNAs) has expanded our view on mammalian genomes
178 gnation of more than 87 predicted "noncoding RNAs" to conventional mRNAs coded by protein-coding gene
179 rotein-coding sequences, producing noncoding RNAs, and even supporting evolution of new protein-codin
180 are evolutionarily conserved small noncoding RNAs that display important physiological effects throug
181 anges in the serum levels of these noncoding RNAs are observed in patients with asymptomatic high-gra
185 OTEIN6 (ORRM6) result in the near absence of RNA editing of psbF-C77 and the reduction in accD-C794 e
186 are dedicated to different research areas of RNA biology including RNA structure analysis, RNA alignm
187 Characterizing the binding behaviors of RNA-binding proteins (RBPs) is important for understandi
189 XR1P) is a member of the fragile X family of RNA-binding proteins, which includes FMRP and FXR2P.
194 to investigate the biophysical mechanisms of RNA folding and unfolding, its interactions with ligands
195 n fragmentation and chemical modification of RNA, rendering it less suitable for analysis by techniqu
202 RNA requires the temporal synchronization of RNA synthesis and ligand binding-dependent conformationa
204 of these modifications and a dynamic view of RNA structure changes with increased numbers of 2-5-link
205 function to be obtained, the availability of RNAs containing this modification at defined positions t
206 tome analysis, an unbiased approach based on RNA sequencing of resistant subclones, to discover the m
207 sequencing confirmed the effect of hDBR1 on RNA splicing, and metabolite profiling supported the obs
208 fluorescence protein (GFP)-mimicking turn-on RNA aptamer, Broccoli, into two split fragments that cou
211 agnostic (CRISPR-Dx), providing rapid DNA or RNA detection with attomolar sensitivity and single-base
212 Loss-of-function mutations in ORGANELLE RNA RECOGNITION MOTIF PROTEIN6 (ORRM6) result in the nea
221 measurements reveal rapid changes in protein-RNA interactions within 1 min following stress impositio
224 -derived RNAs, most prominently 5S ribosomal RNA pseudogene 141 (RNA5SP141), bound to RIG-I during in
225 its, enable bacterial and archaeal ribosomal RNA gene sequences to be followed across multiple studie
226 or many positive-sense single-stranded RNA (+RNA) viruses including human pathogens hepatitis C virus
227 interaction between positive-strand RNA [(+)RNA] viruses and cellular membranes that contribute to t
228 gh-resolution crystal structures of the same RNA duplex containing four and eight 2-5-linkages at dif
234 ary genomic analyses such as RNA sequencing (RNA-Seq), chromatin immunoprecipitation, and ribosome pr
235 g exome sequencing, whole-genome sequencing, RNA-seq, ChIP-seq, targeted sequencing and single-cell w
236 increased binding of total and phospho-Ser2 RNA polymerase II specifically at the intron retained un
237 t need in rapid, reliable detection of short RNA regions which could open up new opportunities in tra
239 uses, paving the way for delineating similar RNA-RNA interactions that govern assembly of other segme
242 mation was associated with low levels of SIV RNA in the brain as shown by in situ hybridization, and
243 chanism of action and show that mobile small RNAs generate sharply defined domains of target gene exp
247 ed protein fold found in several plus-strand RNA viruses that binds to the small molecule ADP-ribose.
248 e on the interaction between positive-strand RNA [(+)RNA] viruses and cellular membranes that contrib
249 ctor for many positive-sense single-stranded RNA (+RNA) viruses including human pathogens hepatitis C
251 R-Cas13a as a flexible platform for studying RNA in mammalian cells and therapeutic development.
258 novel method (RS3D) that can assimilate the RNA secondary structure information, small-angle X-ray s
259 nt idea of pseudoalignment introduced in the RNA-Seq context is highly applicable in the metagenomics
260 f RBPs, including the binding effects of the RNA helicase MOV10 on mRNA degradation, the potentially
261 lustrate that the secondary structure of the RNA molecule-and its absence-plays an essential role in
262 polymerase responsible for synthesis of the RNA primers that are elongated by the replicative DNA po
264 eraction between a peripheral element of the RNA that forms a T-loop module and a subset of nucleotid
265 hat the act of transcription rather than the RNA product itself is functionally important in many cas
267 raction with a combinatorial approach to the RNA folding problem in order to compute all possible non
269 3 mRNA to a shorter ALE isoform of which the RNA, rather than an encoded protein, is critical for the
275 novel, computationally tractable approach to RNA-ligand kinetics, we overcome the two main difficulti
276 applying a gradient-based coarse graining to RNA-ligand systems and solving the process in a pseudo-f
281 d changes in the keratinocyte transcriptome, RNAs isolated from undifferentiated and differentiated c
282 at SIDT1 and SIDT2 not only do not transport RNA, but they are involved in cholesterol transport.
284 ng suggests that the folding path of twister RNA requires proper orientation of the substrate prior t
285 AU-rich elements in diverse RNAs through two RNA-recognition motifs, RRM1 and RRM2, and post-transcri
287 each case, we analyzed gene expression using RNA sequencing and assessed differences between conditio
288 d this, we investigated transcriptomes using RNA-seq and amino acid levels with N treatment in tea (C
292 specific interactions between Gag and viral RNA are required for the enhancement of particle product
293 vious hypothesis that specific dimeric viral RNA-Gag interactions are the nucleation event of infecti
294 hich included detection of hepatitis D virus RNA among anti-hepatitis D virus seropositive participan
300 al proposed that an interaction between Xist RNA and Lamin B receptor (LBR) is necessary and sufficie
301 centiles for the time until the loss of ZIKV RNA detection were 14 days (95% confidence interval [CI]
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