ライフサイエンスコーパス: RNAi

1 RNAi analysis revealed that knockdown of isoatp4056 expr

2 RNAi depletion studies confirmed that ESCRT-III proteins

3 RNAi expression in transgenic endosperm eliminated detec

4 RNAi knock-down of the transcriptional factor Relish2 ab

5 RNAi knockdown lines with less than 30% NBP35 protein su

6 RNAi knockdown of either Cbx3 or Med26 inhibits neural d

7 RNAi prodrugs are modified, self-delivering short interf

8 RNAi therapeutics offer a potential solution, as identif

9 RNAi-induced down-regulation of TbHrg in heme-limited cu

10 RNAi-mediated attenuation of Cav-1 expression reduced up

11 RNAi-mediated attenuation of p73 rescued the transcripti

12 RNAi-mediated attenuation of SMPD1 in human NSCLC cells

13 RNAi-mediated blockade of AKT, HSF1 or HuR is sufficient

14 RNAi-mediated gene silencing of il17a in fibrotic mice a

15 RNAi-mediated silencing of NR4A1 decreased expression of

16 RNAi-mediated silencing of SLC13A5 expression in two hum

17 We employed a RNAi screen simultaneously monitoring different populati

18 in the Drosophila optic lobe, and through a RNAi screen, they identify a transmembrane LRR protein-L

19 In addition, RNAi research on new fungal models has uncovered the rol

20 Although RNAi has revolutionized loss-of-function genetic experim

21 An RNAi suppressor screen identified survival of motor neur

22 In this study, we conducted an RNAi-based screen to identify druggable chromatin regula

23 CD44 was recently identified in an RNAi screen of blood group genes as a host factor for in

24 In an RNAi-based screen, we identified alphaSNAP (soluble NSF

25 ally study ERV repression, we carried out an RNAi screen in mouse embryonic stem cells (ESCs) and ide

26 We performed an RNAi-based screen of human lysine methyltransferases and

27 Through an RNAi screen in the developing Drosophila eye, we found t

28 We used an RNAi approach and radiotracer assays to explore which LR

29 sion of LRRC8 proteins was modified using an RNAi approach, and amino acid fluxes via VRAC were quant

30 with a mutant line for CG13646, and with an RNAi approach.

31 hose that limit the persistence of ancestral RNAi by, for example, employing negative feedback loops

32 splicing using pharmacological, genetic, and RNAi approaches demonstrates that this adaptive response

33 Cluster analysis, in situ hybridization and RNAi assays indicate that males likely use biogenic amin

34 Gene inactivation and RNAi-mediated knockdown of AtCPT7 eliminated leaf polypr

35 Here we show by microarray and RNAi that guanine nucleotide-binding protein subunit alp

36 ntroduce a genome-scale microcantilever- and RNAi-based approach to phenotype the contribution of > 1

37 s a public repository for small-molecule and RNAi screening data since 2004 providing open access of

38 w of the different classes of small RNAs and RNAi pathways in fungi and their roles in the defense of

39 els has uncovered the role of small RNAs and RNAi pathways in the regulation of diverse biological fu

40 Using gene targeting and RNAi, we showed that depletion of the nonsense-mediated

41 ation of host factors required for antiviral RNAi in Arabidopsis thaliana Using whole-genome sequenci

42 to et al. describe a mechanism for antiviral RNAi spreading that parallels mammalian adaptive immunit

43 -type ATPases as key components of antiviral RNAi.

44 lial cells and is regulated by the antiviral RNAi pathway of the host.

45 es deficient for components of the antiviral RNAi pathway, such as Dicer-related helicase 1 (DRH-1),

46 Our results suggest that the antiviral RNAi response not only inhibits vertical VSV transmissio

47 In contrast to transient therapies (such as RNAi), we show that ZNP delivery of sgRNA enables perman

48 f mass spectrometry, RNA-seq, enzyme assays, RNAi and phylogenomics in different non-model species.

49 c8 or the cyclin Crs1 suppresses UPD in both RNAi and mmi1 mutants.

50 that T. brucei, L. mexicana and a T. brucei RNAi morphology mutant have a range of shape asymmetries

51 -90% decrease in NOX1 expression achieved by RNAi produced a significant decline in ROS production an

52 regulating CDKN2A This idea was confirmed by RNAi-mediated suppression or genetic deletion of ETS1, w

53 Rif1 depletion by RNAi or gene deletion led to increased transcription and

54 in which NOX1 expression was knocked down by RNAi.

55 and Smt3 (the SUMO isoform in Drosophila) by RNAi prevents Smo accumulation and alters Smo activity i

56 d that suppressing male NlPHF7 expression by RNAi led to decreases in body weight, soluble accessory

57 s in Kenya, and reducing FBN30 expression by RNAi makes mosquitoes more susceptible to P. berghei.

58 een Smo and Ulp1 because knockdown of Krz by RNAi attenuates Smo-Ulp1 interaction.

59 Reduction of H2AV levels by RNAi knockdown caused a milder phenotype that preserved

60 Targeting Rac1 signaling by RNAi, expression of the dominant-negative Rac1 (Rac1 DN)

61 the Drosophila ortholog of SOX5, Sox102F, by RNAi in various neuronal subtypes in Drosophila.

62 et of human tumors, and their suppression by RNAi caused a decrease in cancer cell survival and growt

63 rference (RNAi) is mediated by the canonical RNAi machinery and can lead to transcriptional silencing

64 i/shRNAs kill cancer cells through canonical RNAi by targeting the 3'UTR of critical survival genes i

65 In these cells, RNAi-mediated depletion or chemical inhibition of AURKA

66 Interestingly, CLIPA14 RNAi phenotypes and its infection-induced cleavage were

67 In addition, we compared RNAi technology to clustered regularly interspaced short

68 In this study, we designed a comprehensive RNAi strategy targeting the conserved domain of the PRSV

69 nificant locomotor phenotypes, and conducted RNAi with ubiquitous, pan-neuronal, or motor-neuronal Ga

70 endosomal escape, and cholesterol-conjugated RNAi triggers, which together result in HBV gene silenci

71 c and functional alterations induced by Coq2-RNAi.

72 tly of CoQ10, phenocopied the effect of Coq2-RNAi.

73 thione partially rescued the effects of Coq2-RNAi.

74 Here, we identified the ALB core RNAi genes including those coding for Dicer, Argonaute,

75 d with euchromatic transcription, and couple RNAi-mediated transcript degradation to the establishmen

76 Consistent with these data, RNAi knockdown of Sigma1 resulted in decreased AR levels

77 Both SUFC- and SUFD-deficient RNAi lines accumulated the same intermediate, suggesting

78 suggesting that the difficulty of detecting RNAi in virus-infected mammalian cells reflects the expr

79 n, were identified as hits in four different RNAi screens and we therefore studied their potential as

80 Insects exploit two different RNAi pathways to combat viral and transposon infection:

81 e major factors contributing to differential RNAi efficiency reported among insects.

82 The FlyRNAi database of the Drosophila RNAi Screening Center (DRSC) and Transgenic RNAi Project

83 fish, implying that most fish lack effective RNAi.

84 RNA locus, thereby attaining what has eluded RNAi and RNase H experiments: elimination of MRP RNA in

85 and CDKN2A protein expression, whereas ETS1 RNAi blocked this increase.

86 ely to have contributed to truncation of eve(RNAi) embryos.

87 odulate tissue-specific silencing by feeding RNAi in other invertebrates.

88 ells is not an obligatory feature of feeding RNAi in C. elegans.

89 Finally, RNAi-mediated down-regulation of host autophagy protein

90 Following RNAi-mediated knockdown, 15 of the genes modulated mitoc

91 and the lethal phenotype observed following RNAi-mediated silencing of the Trypanosoma brucei SODA o

92 lity phenotyping (Worminator), and dsRNA for RNAi for functional genomic studies that have revealed,

93 tumorigenesis offer novel opportunities for RNAi-mediated targeting of BTICs.

94 ding interactions with proteins required for RNAi activity and may be a promising modification for op

95 tion from H3K9me2 to H3K9me3 is required for RNAi-independent epigenetic inheritance of H3K9me domain

96 heterochromatin state that is sufficient for RNAi-dependent co-transcriptional gene silencing at peri

97 r development of translational, carrier-free RNAi-based cancer therapies.

98 Applying eUnaG in functional RNAi screens, we characterize l(2)03659 as a Drosophila

99 These data suggest that functional RNAi machinery exists in ALB and a potential RNAi-based

100 Furthermore, RNAi-mediated depletion of CIB1 in primary dopaminergic

101 otentiate the development of next-generation RNAi pathway-based therapeutics and promises to accelera

102 and screened for loss of fitness after 48 h RNAi.

103 inheritance of small RNAs and for heritable RNAi in worms, which typically persist for a finite numb

104 ents a powerful in vivo strategy to identify RNAi-based nanotherapeutics with potent gene silencing a

105 Seed-specific repression of AtCGS in RNAi seeds triggered the induction of genes operating in

106 had greater expression of genes involved in RNAi, Toll, Imd, and JAK-STAT pathways, but the majority

107 We summarize recent progress in RNAi-mediated insect pest control and discuss factors de

108 The metabolic rearrangements in RNAi seeds resulted in an altered sulfur-associated meta

109 Argonaute (Ago1), plays an important role in RNAi-mediated heterochromatinization.

110 However, variability in RNAi efficiency among insects is preventing the widespre

111 earch to identify reasons for variability in RNAi efficiency among thirty-seven (37) insects belongin

112 Depletion of mst using three independent RNAi lines expressed by a pan-muscular driver elicited c

113 Oral delivery failed to induce RNAi effects and we suggest this is attributable to degr

114 mperature-sensitive Gal80 molecule to induce RNAi-mediated depletion of dpp and characterise the spat

115 Expression of GFP-tagged POMP10 in inducible RNAi cell lines shows that its mitochondrial localizatio

116 By integrating RNAi screening data, we identify components of the shape

117 beta1-integrin(RNAi) animals formed small head blastemas with severe ti

118 or cells were mislocalized in beta1-integrin(RNAi) animals without significantly altered body-wide pa

119 l molecule that stimulates RNA interference (RNAi) and acts as a growth inhibitor selectively in canc

120 sect control methods using RNA interference (RNAi) are being developed.

121 The importance of RNA interference (RNAi) as a mammalian antiviral defense mechanism has bee

122 complementation system and RNA interference (RNAi) assays, we found that ESCRT-I and ESCRT-III comple

123 al targets for therapeutic RNA interference (RNAi) in both early and late presentations.

124 While the use of RNA interference (RNAi) in molecular biology and functional genomics is a

125 RNA interference (RNAi) in transgenic maize has recently emerged as an alt

126 fficient gene silencing by RNA interference (RNAi) in vivo requires the recognition and binding of th

127 RNA interference (RNAi) is a conserved eukaryotic mechanism that uses smal

128 RNA Interference (RNAi) is a potentially useful tool to correct the detrim

129 Such feeding RNA interference (RNAi) is best understood in the worm Caenorhabditis eleg

130 RNA interference (RNAi) is known for its high catalytic activity and targe

131 Nuclear RNA interference (RNAi) is mediated by the canonical RNAi machinery and ca

132 In arthropods, RNA interference (RNAi) is responsible for antiviral defense.

133 utants, laf6 and hmc1, and RNA interference (RNAi) lines with reduced SUFB expression.

134 d show that defects in the RNA interference (RNAi) machinery or in the YTH domain-containing RNA elim

135 sRNAs) associated with the RNA interference (RNAi) pathway.

136 fective in their antiviral RNA interference (RNAi) response, and is neither lethal nor vertically tra

137 signaling was modulated by RNA interference (RNAi) revealed that B cells were the primary target cell

138 We adapted pooled RNA interference (RNAi) screening technology for use in orthotopic patient

139 sis (Arabidopsis thaliana) RNA interference (RNAi) seeds with lower transcript expression of CYSTATHI

140 Plant-mediated RNA interference (RNAi) shows great potential in crop protection.

141 LN-PCSsc) is a long-acting RNA interference (RNAi) therapeutic agent that inhibits the synthesis of p

142 LN-GO1, an investigational RNA interference (RNAi) therapeutic targeting glycolate oxidase, to deplet

143 usiran, an investigational RNA interference (RNAi) therapy that targets antithrombin (encoded by SERP

144 we investigate the use of RNA interference (RNAi) to control two dipteran pests, Musca domestica and

145 The application of RNA interference (RNAi) to mammalian cells has provided the means to perfo

146 ical applications using an RNA interference (RNAi)-based approach.

147 RNA interference (RNAi)-based gene regulation platforms have shown promise

148 Large-scale RNA interference (RNAi)-based screens have identified nearly a thousand ca

149 The RNA interference (RNAi)-based therapeutic ARC-520 for chronic hepatitis B

150 The RNA interference (RNAi)-induced transcriptional silencing (RITS) complex,

151 anscriptional change using RNA interference (RNAi)-mediated knock-down of genes belonging to the cath

152 ne silencing together with RNA interference (RNAi).

153 alternative to transgenic RNA interference (RNAi).

154 c and p53-elevated phenotypes, we used IP6K2 RNAi and the pan-IP6K inhibitor, N2-(m-trifluorobenzyl),

155 We identified homologs of key RNAi genes in the genomes of some of these insects and s

156 Notably, in cells lacking RNAi components or Mmi1, UPD is associated with the unti

157 Mechanistically, RNAi-mediated attenuation of DUSP4 activated the ERK and

158 thiourea (IR415), which blocked HBx-mediated RNAi suppression indicated by the GFP reporter assay.

159 reproductive fitness through plant-mediated RNAi, demonstrating the feasibility of reproductive RNAi

160 expressed in the germline and that mediates RNAi through piRNAs.

161 MELK RNAi and small-molecule inhibitors of MELK block the pro

162 Moreover, RNAi-mediated knockdown of YY1 in GC cells significantly

163 orm with the capacity to channel multiplexed RNAi schemes to address the challenges posed by tumor he

164 e that 7C1 nano-encapsulation of multiplexed RNAi is a viable BTIC-targeting strategy when delivered

165 monstrate a method for production of a novel RNAi scaffold, packaged within Qbeta virus-like particle

166 potent suppressors of morc-1(-) and nuclear RNAi mutant phenotypes.

167 eins act together with the piRNA and nuclear RNAi pathways to silence repetitive elements and prevent

168 Without MORC-1 and nuclear RNAi, MET-1-mediated encroachment of euchromatin leads t

169 ires repression of MET-1 activity at nuclear RNAi targets.

170 tead requires both maternal germline nuclear RNAi and chromatin-modifying activity.

171 t silencing is dependent on germline nuclear RNAi factors and post-transcriptional mechanisms.

172 Further analysis of nuclear RNAi and morc-1(-) mutants revealed a progressive, met-1

173 c silencing does not require somatic nuclear RNAi but instead requires both maternal germline nuclear

174 To prove that nuclear RNAi occurs and modulates transcription in human cells,

175 ve characterized the dynamics of the nuclear RNAi process in living human cells.

176 ive-cell imaging to detect and track nuclear RNAi transcriptional repression in single living human c

177 A method enables pharmacokinetic analysis of RNAi triggers, elucidates potential metabolic processing

178 This combination of RNAi scaffold design with Qbeta VLP packaging is demonst

179 a suppressor of host defenses consisting of RNAi-based silencing of viral genes.

180 tes nanotechnology developed for delivery of RNAi for human therapeutics to use in crop protection as

181 as become transformative for the delivery of RNAi therapeutics as well as other classes of investigat

182 nt implications in the efficient delivery of RNAi therapeutics in vitro and in vivo.

183 microRNA (miRNA)-like off-target effects of RNAi are far stronger and more pervasive than generally

184 at segregates on- from off-target effects of RNAi.

185 Techniques in preclinical evaluation of RNAi-based nanoconjugates have yet to allow for optimiza

186 ilamentous fungi, the protective function of RNAi in the maintenance of genome integrity is well know

187 The implementation of RNAi technology into the clinical practice has been sign

188 To characterize the kinetics of RNAi trigger delivery and 5-phosphorylation of guide str

189 MM that was synthesized in rosette leaves of RNAi plants significantly contributed to the accumulatio

190 Golgi structure, indicating a limitation of RNAi-based depletion.

191 e is in turn required for the recruitment of RNAi to chromatin to promote the amplification of sRNA.

192 ion of highly effective viral suppressors of RNAi.

193 Under the salt stress, the T3 of RNAi plants showed significant higher resistance.

194 iPIP2;3) were significantly changed in T3 of RNAi plants.

195 le, examination of the leaves from the T3 of RNAi transformants indicated reduction of cell expansion

196 Mechanistic investigations based on RNAi or CRISPR approaches implicated the RNA binding pro

197 In the current work, mutation or RNAi-mediated knockdown in the stellate cells of the tub

198 Overexpression or RNAi-mediated knockdown of neuroligins, respectively, ca

199 Mibefradil treatment or RNAi-mediated attenuation of Cav3.2 was sufficient to in

200 1, Ino80C, or NC2 by anchor away in yeast or RNAi in mESCs leads to near-identical transcriptome phen

201 protein amount, which was inhibited by p300 RNAi.

202 Phe, and decreased PhCAT2 expression in PAL-RNAi transgenic plants resulted in 1.6-fold increase in

203 onally important Tat cofactors, we performed RNAi knockdowns of sixteen previously identified Tat int

204 orientations to construct recombinant plant RNAi vectors.

205 This is the first study to employ in planta RNAi approach to target the Rs-cps gene for the control

206 To evaluate the effect of in planta RNAi on the control of this nematode, a specific fragmen

207 Employing pooled RNAi and yeast two-hybrid screenings, we report that the

208 RNAi machinery exists in ALB and a potential RNAi-based method could be developed for controlling thi

209 ell death generally prefigured Dermestes PRG RNAi-mediated cuticle defects, an organized region with

210 Although prior RNAi studies reported prevalent lethality among young ge

211 -microRNA hairpins after splicing, producing RNAi effectors not processed by Drosha.

212 of regulatory mechanisms: those that prolong RNAi inheritance through amplification and maintenance o

213 se orientations to construct the recombinant RNAi vector.

214 of green fluorescent protein (GFP)-reported, RNAi-mediated silencing in a HepG2/GFP-shRNA RNAi sensor

215 at cancer cells re-express PIWIL3 to repress RNAi through miRNAs and thus open a new opportunity for

216 emonstrating the feasibility of reproductive RNAi as a management tool for western corn rootworm.

217 ese results provide a strategy for restoring RNAi to zebrafish and reveal unanticipated opposing effe

218 loped novel mouse models allowing reversible RNAi-based control of Ikaros expression in established B

219 is abolished in ROP-deficient rop2 rop6 ROP4 RNAi plants.

220 cancer subtypes, we conducted a large-scale RNAi screen in which viability effects of mRNA knockdown

221 detrimental effects of faulty genes; several RNAi are undergoing clinical evaluation in various disea

222 RNAi-mediated silencing in a HepG2/GFP-shRNA RNAi sensor line.

223 Simultaneous RNAi gene silencing of ClAQP1 and ClGlp1 significantly r

224 sirt2 RNAi also phenocopies mir-92a overexpression.

225 imultaneously targeted by endosperm-specific RNAi.

226 to enable a genome-wide mesodermal-specific RNAi screen and discovered 39 factors in mesodermal cell

227 Using tissue-specific RNAi-mediated knockdown, we showed that Fmr1 plays a cel

228 d to be significantly downregulated in SPL13 RNAi silencing plants.

229 Here we provide evidence for successful RNAi in EAB, and demonstrate the development of a rapid

230 ight, the laf6 and hmc1 mutants and the SUFB RNAi lines accumulated higher levels of the chlorophyll

231 ut this was not observed in hmc1 or the SUFB RNAi lines, nor was it complemented by SUFB overexpressi

232 when the virus-encoded function to suppress RNAi was disrupted.

233 how that flies have a sophisticated systemic RNAi-based immunity mediated by macrophage-like haemocyt

234 involved in dsRNA transport and the systemic RNAi.

235 n dsRNA are sufficient to trigger non-target RNAi effects.

236 Through a targeted RNAi screen examining the relevance of selected TRIM pro

237 shift in our focus from a single technology (RNAi) and model species (Drosophila) to the application

238 that SmgGDS localizes in nucleoli, and that RNAi-mediated depletion of SmgGDS in cancer cells disrup

239 We further demonstrated that RNAi-mediated ABHD5 silencing promotes, whereas ectopic

240 This study demonstrates that RNAi silencing of a member of the Bone Morphogenetic Pro

241 We discovered that RNAi is less effective in zebrafish at least partly beca

242 ouse xenograft models of DCIS, we found that RNAi-mediated silencing of NEMO increased tumor invasion

243 Here we report that RNAi-mediated suppression of Oryza sativa GRXS17 (OsGRXS

244 We demonstrate for the first time that RNAi prodrugs (siRNNs) targeting Plk1, can enter pediatr

245 The RNAi pathway provides both innate immunity and efficient

246 The RNAi scaffold is a general utility chimera that contains

247 The RNAi-mediated depletion of UBF diminishes nucleolar loca

248 i assembles upon co-expression of CP and the RNAi scaffold in E. coli.

249 NA or pre-siRNA as proper substrates for the RNAi pathway.

250 nalysis confirmed that the expression of the RNAi apparatus could repress expression of the CesA gene

251 promoters, which may facilitate therapeutic RNAi applications where delivery vector space is limitin

252 Through RNAi and analysis of an insertion mutant, we identified

253 get gene for managing BPH population through RNAi.

254 f western corn rootworm reproduction through RNAi by targeting two reproductive genes, dvvgr and dvbo

255 with mass spectrometry and a high throughput RNAi screen.

256 TmCactin RNAi significantly decreased the survival rates of larva

257 Furthermore, TmCactin RNAi significantly reduced the expression of seven antim

258 luorescent sense strand PNA probe binding to RNAi duplex guide strands was coupled with anion exchang

259 sential noncoding RNAs that are resistant to RNAi and RNase H-based degradation.

260 We propose that specific toxic RNAi-active sequences present in the genome can kill can

261 RNAi Screening Center (DRSC) and Transgenic RNAi Project (TRiP) at Harvard Medical School and associ

262 Currently, transgenic RNAi-based control has focused on suppression of genes t

263 eneration and characterization of transgenic RNAi lines of the obligate CAM species Kalanchoe fedtsch

264 in the sense or antisense strands triggered RNAi-mediated gene silencing with efficiencies comparabl

265 We found that upon RNAi mediated depletion of EMILIN-1 in primary calvarial

266 s tissues and developmental stages, and used RNAi-based methods to generate knockdown phenotypes of A

267 y in conjunction with S-RNase, and then used RNAi to test whether they also function in S-RNase-indep

268 Using RNAi and overexpression of wild-type and ALS-associated

269 Using RNAi and tracer endocytosis as a functional read-out, we

270 Using RNAi perturbations, we found that blastodermal fates cou

271 Using RNAi screening for defects in Caenorhabditis elegans anc

272 Using RNAi screening in Drosophila cells, we identify many cor

273 osomes in the bloodstream was assessed using RNAi target sequencing (RITseq) and compared to growth i

274 es were tested in the Drosophila heart using RNAi-based gene silencing.

275 Finally, studies using RNAi-rescue systems in human cells revealed that intact

276 h as HAND2-AS1, were further validated using RNAi-based loss-of-function assays.

277 Therapeutic targeting of CcnE1 in vivo using RNAi is feasible and has high antifibrotic activity.

278 dependent kinase in honey bees, we utilized RNAi to reduce their expression in vivo and determined t

279 changes in histone and DNA modifications via RNAi-mediated recruitment of chromatin-modifying enzymes

280 Inhibition of PKM2 via RNAi or chemical inhibitors may be a highly effective ap

281 We show that down-regulation via RNAi of a single head patterning gene-orthodenticle-indu

282 MAGUK removal via RNAi-mediated knockdown in the CA1 hippocampal region in

283 technology for the development of anti-viral RNAi delivery systems against influenza virus infection.

284 We assessed lncRNA function via an in vivo RNAi screen in a model of acute myeloid leukemia.

285 We investigated this by inducing in vivo RNAi vector-based knockdown of MCT8 in neural progenitor

286 The VLP-RNAi assembles upon co-expression of CP and the RNAi sca

287 on of GFP expression in human cells with VLP-RNAi.

288 When RNAi-treated nematodes succeeded in infecting the plant,

289 ics identified 16 new IRF5 interactors while RNAi-mediated knockdown found 43 regulators of the TLR7-

290 sets include published data from genome-wide RNAi and CRISPR screens, interactome proteomics and phos

291 A previous genome-wide RNAi screen for suppressors of clozapine-induced develop

292 cally with ubc-18 in an unbiased genome-wide RNAi screen in C. elegans These two E2s have nonoverlapp

293 In recent years genome-wide RNAi screens have revealed hundreds of cellular factors

294 Here, we use a genome-wide RNAi-synthetic lethal screen and transcriptomic profilin

295 A recent kinome-wide RNAi screen with 176 individual bloodstream form Trypano

296 Using unbiased kinome-wide RNAi screening followed by thorough validation, we ident

297 nocking down the ecdysone receptor gene with RNAi resulted in an increased production of winged offsp

298 can persistently coexist in a protozoan with RNAi activity and how these two entities work to maintai

299 , SPL5, and SPL9, is upregulated in CmNF-YB8-RNAi plants, while expression of the microRNA, cmo-MIR15

300 enesis of "conserved, essential" and "young, RNAi-lethal" genes and broadly confirmed the lethality o