ライフサイエンスコーパス: RNP

1 RNP delivery of BE3 confers higher specificity even than

2 RNP filaments were traced in three dimensions (3D), and

3 RNP granules are ribonucleoprotein assemblies that regul

4 RNP granules formed by ALS-linked mutant TDP-43 are more

5 RNP granules formed from wild-type TDP-43 show distinct

6 RNP was associated with the membrane whenever the M laye

7 RNP-disrupting mutations in Prp3 lead to U4/U6*U5 tri-sn

8 -type sialic acid receptors, and that pdm/09 RNP conferred the most robust polymerase activity to rea

9 erlying the dynamic equilibrium of the LAF-1 RNP complex.

10 Here, we show that TDP-43 RNP granules in axons of rodent primary cortical neurons

11 tes that the stabilized population of TDP-43 RNP granules in the proximal axon is less circular and s

12 nce of NS1, both in the context of segment 7 RNPs reconstituted by plasmid transfection and in mutant

13 Comparison of the derived +A RNP shape with that of the previously reported precursor

14 in (Cbf5 in yeast) at an early step of H/ACA RNP assembly and is subsequently displaced by the H/ACA

15 on with minimized hTR, indicating that H/ACA RNP assembly enhances endogenous hTR-TERT interaction.

16 s the position of CS domain in the pre-H/ACA RNP was calculated using the CSP data.

17 onale for human telomerase assembly as H/ACA RNP, we developed a minimized cellular hTR.

18 , proteins known to be present on additional RNP particles were identified, including Y box-binding p

19 After RNP IC stimulation of neutrophils, mitochondria become h

20 KMIP1 is a component of polyribosomes and an RNP translational regulatory complex that includes fragi

21 reas NP associates with viral RNA to form an RNP complex that associates with the cytoplasmic face of

22 te binding and catalytic (TBC) channel in an RNP reconstitution system.

23 ex coacervation and subsequently triggers an RNP charge inversion, which promotes disassembly.

24 eneral paradigm wherein the phenotype of an "RNP assembly disease" might be suppressed by inhibition

25 gRNP docking, pre-mRNA and RECC loading, and RNP formation with a short synthetic RNA duplex.

26 al particles and is positioned between M and RNP.

27 and phospho-regulates NP oligomerization and RNP assembly during infection.

28 se-driven exportin that carries proteins and RNPs from the nucleus to the cytoplasm.

29 t function to manipulate structured RNAs and RNPs.

30 Vaccination with irradiated anti-RNP (but not anti-tetanus toxoid) CD4(+) cells induced r

31 ay be important for the pathogenesis of anti-RNP lupus and other autoimmune diseases.

32 d the relevance of a conserved class of anti-RNP T cells to autoimmune disease expression and therapy

33 xoid) CD4(+) cells induced remission of anti-RNP-associated nephritis in >/= 80% of treated mice, eve

34 practical development of a standardized anti-RNP T cell vaccine preparation useful for multiple patie

35 Our data show that anti-RNP T cell selection induced a limited set of homologous

36 Fus is not required for APC-RNP localization but is required for efficient translati

37 Here, we show that APC-RNPs associate with the RNA-binding protein Fus/TLS (fus

38 rococcus furiosus (Pfu) RNase P, an archaeal RNP that catalyzes tRNA 5' maturation.

39 al base-pairing characteristics of Argonaute RNPs to bind mRNAs randomly in Drosophila, acting as an

40 ltiple RNA-protein assemblies referred to as RNP granules, which are thought to form through multiple

41 and virus particles, where N is assembled as RNPs.

42 a role for dual specificity phosphatases at RNP particles and suggest that hYVH1 may affect a variet

43 FXGs (Fragile X granules) are axonal RNPs present in a stereotyped subset of mature axons in

44 ally, we apply these advances to deliver BE3 RNPs into both zebrafish embryos and the inner ear of li

45 analysis also reveals a correlation between RNP localization within the viral particle and the forma

46 ce illustrating that M2-1 is located between RNP and M in isolated viral particles.

47 is mRNP from mitochondria lacking gRNA-bound RNP (gRNP) subcomplexes and identified REH2-associated c

48 We have shown that the p50-bound RNP catalytic core has a relatively low rate of tandem r

49 on sequencing of RNA isolated from the Cyt c-RNP complex reveals that 20 tiRNAs are highly enriched i

50 t 20 tiRNAs are highly enriched in the Cyt c-RNP complex.

51 released Cyt c in a ribonucleoprotein (Cyt c-RNP) complex.

52 Cas9 RNP electroporation caused up to approximately 40% of ce

53 Cas9 RNP-mediated HDR in HEK293T, human primary neonatal fibr

54 These results establish Cas9 RNP technology for diverse experimental and therapeutic

55 ol for combined Cas9 ribonucleoprotein (Cas9 RNP)-mediated gene editing and lentiviral transduction t

56 Cas9 RNPs allowed ablation of CXCR4, a coreceptor for HIV ent

57 Importantly, Cas9 RNPs paired with homology-directed repair template oligo

58 s9:single-guide RNA ribonucleoproteins (Cas9 RNPs).

59 uencing of a target site confirmed that Cas9 RNPs generated knock-in genome modifications with up to

60 seq datasets for 60 human RBPs and RIP-ChIP (RNP immunoprecipitation-microarray) data for 69 yeast RB

61 and donor templates, we show that combining RNP and AAV donor delivery increases the efficiency of g

62 Here, we demonstrate that combining RNP delivery with naturally recombinogenic adeno-associa

63 However, combining RNPs with transgene-containing donor templates for targe

64 n of grk mRNA in a translationally competent RNP complex that contains the translational activator Oo

65 l component of the viral RNA genome complex (RNP).

66 genome and form a ribonucleoprotein complex (RNP) together with viral polymerase.

67 ein N to form the ribonucleoprotein complex (RNP).

68 Ribonucleoprotein immune complexes (RNP ICs), inducers of NETosis, require mitochondrial rea

69 RNA-protein complexes (RNPs) formed by the hepatitis delta virus RNAs and prote

70 y structured RNAs and RNA-protein complexes (RNPs) in many essential cellular processes.

71 of specific noncoding RNA-protein complexes (RNPs) in vivo, we developed comprehensive identification

72 achinery, large ribonucleoprotein complexes (RNPs) composed of the viral polymerase, genomic RNA and

73 The ribonucleoprotein complexes (RNPs) formed by these RNAs with the virus-encoded protei

74 e remodeling of ribonucleoprotein complexes (RNPs), allowing formation of native RNA structure or pro

75 The factors controlling RNP bodies and connections to RNA regulation are unclear

76 Our methodology, designated as CRISPR RNP Electroporation of Zygotes (CRISPR-EZ), enables high

77 ment of new protein synthesis by cytoplasmic RNP granules in axon terminals, where RNP granules regul

78 colocalized with Gag and YB-1 in cytoplasmic RNP complexes.

79 general role for these types of cytoplasmic RNP granules in the survival of G0-like resting cells.

80 aenorhabditis elegans oogenesis, cytoplasmic RNPs can transition among diffuse, liquid, and solid sta

81 nents reveals that PRPF8 depletion decreases RNP complex formation at most splice sites in exon-intro

82 ering measurements, and no increase in Delta%RNP is observed in the presence of either FLAG octapepti

83 used to estimate that a 1% increase in Delta%RNP observed in SPRM corresponds to the incorporation of

84 nto the 220 nm HNPs was an increase in Delta%RNP of 0.15%, corresponding to the absorption of 10000 m

85 The value of Delta%RNP increased linearly from 1.04 +/- 0.04 to 2.10 +/- 0.

86 noparticle SPRM reflectivity response, Delta%RNP, was measured.

87 We show that ATP-dependent RNP remodeling by Vasa facilitates transfer of 5' sliced

88 Which model describes RNP granules in living cells is still unclear.

89 protein (RNP) granule components and disrupt RNP granule function.

90 nally and, remarkably, structurally distinct RNPs, telomerase, and RNases P/MRP from unrelated progen

91 ile liquid-liquid phase separation may drive RNP granule assembly, the mechanisms underlying their su

92 te immune response, the interactions of each RNP subunit with retinoic acid-inducible gene I protein

93 ed extensive PTBP1-modulated changes in exon RNP composition.

94 e that during early stages of splicing, exon RNP complexes are highly dynamic with many proteins fail

95 rupture, promoting fusion pore widening for RNP release.

96 wever, primary transcription from pre-formed RNPs deposited by infecting particles is unaffected.

97 he translocation of longer 3' UTR mRNAs from RNPs to polysomes correlated with the production of new

98 PP21RPP29 and POP5RPP30) revealed functional RNP intermediates en route to the RNase P enzyme, but pr

99 Aub is a central component of germ granule RNPs, which house mRNAs in the germ plasm, and interacti

100 des insight into the formation of hantavirus RNP and provides an understanding of the evolutionary co

101 s NP, furthering the knowledge of hantavirus RNP formation, revealing the relationship between hantav

102 f RNA to N promotes the formation of helical RNPs, which are a characteristic hallmark of many negati

103 RNA silencing through binding of these host RNP proteins was not identified for this viral suppresso

104 and importin alpha, which is crucial for IAV RNP nuclear translocation.

105 s found to interact with NP component of IAV RNPs during early stages of infection.

106 40 resulted in reduced nuclear import of IAV RNPs, diminished viral polymerase function and attenuate

107 Our data imply that Drosophila Imp RNPs may function as cytoplasmic mRNA assemblages that e

108 GeoCas9 provides the foundation for improved RNP delivery in vivo and expands the temperature range o

109 des an NP that plays essential roles both in RNP formation and in multiple biological functions.

110 To address a proviral role for N(pro) in RNP granules, we investigated whether N(pro) affected RN

111 new functions of poly(A) tail regulation in RNP dynamics.

112 DEAD box RNA helicases play central roles in RNP biogenesis.

113 rter 3' UTRs became increasingly enriched in RNPs from pachytene spermatocytes to round spermatids, a

114 nd the enrichment of shorter 3' UTR mRNAs in RNPs coincided with newly synthesized miRNAs that target

115 h precision tracking reveals that individual RNPs within a population undergo either diffusive, or hi

116 fold protein to gain molecular insights into RNP granule structure and assembly.

117 cesses that can create an influx of RNA into RNP granules, such as transcription, can spatiotemporall

118 g sites, which, therefore, are targeted into RNPs for enrichment and delayed translation.

119 uctural properties of active group II intron RNP particles (+A) isolated from its native host using a

120 monstrate that the disordered regions of key RNP granule components and the full-length granule prote

121 ystem to express and purify highly active L1 RNP complexes from human suspension cell culture and cha

122 d RNAs [L1, Alu and SINE-VNTR-Alu (SVA)], L1-RNPs are enriched with cellular mRNAs, which have PPs in

123 process for the nuclear export of very large RNPs and protein aggregates.

124 es, and the core infectious viral machinery (RNP and polymerase) was present inside the intercellular

125 es, and the core infectious viral machinery (RNP and polymerase) was present inside the intercellular

126 dary structure in the formation of a minimal RNP and visualized the structure of this RNP using atomi

127 use, semiliquid, or solid states to modulate RNP sorting and exchange in the Caenorhabditis elegans o

128 ghout myocyte differentiation into myotubes, RNP immunoprecipitation (RIP) analysis indicated that AU

129 tron microscopy (EM) visualization of native RNPs extracted from the virions revealed that a monomer-

130 s on the Paramyxovirinae subfamily of native RNPs, indicating that it closely represents one-turn in

131 vity in transcription assays that require no RNP assembly.

132 D small (nucleolar) ribonucleoproteins [s(no)RNPs] catalyze 2'-O-methylation, one rRNA modification t

133 majority of genes promote or suppress normal RNP body assembly, dynamics, or metabolism.

134 enables the unbiased identification of novel RNP granule components, paving the way towards an unders

135 he ability of its four heterogeneous nuclear RNP-K-homology (KH) domains to physically associate with

136 ssociated huge protein) and U7 small nuclear RNP (snRNP) are HLB components that participate in 3' pr

137 trans-splicing, which binds U1 small nuclear RNP (snRNP) through strong base-pairing with U1 snRNA.

138 The 7SK small nuclear RNP (snRNP), composed of the 7SK small nuclear RNA (snRN

139 By using an assay to ectopically nucleate RNP granules, we further establish that RNP granule form

140 ge of patients showed a reduction in area of RNP and a lower percentage showed an increase in area of

141 wer percentage showed an increase in area of RNP compared with subsequent periods of ranibizumab PRN

142 ependent reading center measured the area of RNP on fluorescein angiograms obtained in the phase 3 RI

143 showed reduction or increase in the area of RNP.

144 n repressors induce an intrinsic capacity of RNP components to coassemble into either large semiliqui

145 One class of RNP granules consists of P bodies, which consist of nont

146 demonstrate that RNA, a primary component of RNP granules, can modulate the phase behavior of RNPs by

147 ZBP1 is a component of RNP transport particles and is known for its role in the

148 action likely contributes to the fluidity of RNP droplets.

149 n and suggest a morphoregulatory function of RNP granules during health and disease.

150 Here, we identified 66 modifiers of RNP solids induced by cgh-1 mutation.

151 vely, these findings suggest new pathways of RNP modification that control large-scale coassembly and

152 om sham at month 6 halted the progression of RNP and resulted in improvement in both CRVO and BRVO.

153 GF, which then contributes to progression of RNP and thus worsening of ischemia.

154 ser showed significantly less progression of RNP compared with patients treated with ranibizumab PRN.

155 romote improvement and reduce progression of RNP compared with PRN injections.

156 to ranibizumab PRN may reduce progression of RNP in patients with BRVO, but a statistically significa

157 proteins that promote RNA rearrangements of RNP complexes including the spliceosome and ribosome.

158 f the PGL RNase activity expands the role of RNP granule assembly proteins to include enzymatic activ

159 to gain insight into the potential roles of RNP subunits in the modulation of the host's innate immu

160 Thus, we propose that the material state of RNP granules is flexible and that the solid state of yea

161 Trypanosomes have several types of RNP granules, but lack most of the granule core componen

162 , paving the way towards an understanding of RNP granule function.

163 ial RNA processing reactions in a variety of RNP bodies.

164 Atomic force microscopy analysis of RNPs formed in vitro revealed complexes in which the HDV

165 granules, can modulate the phase behavior of RNPs by controlling both droplet assembly and dissolutio

166 analysis of protein and RNA constituents of RNPs, we identify extensive cross-regulatory and hierarc

167 The subunits were in excess of RNPs (e.g. approximately 1150 hTR and approximately 500

168 Electron microscopy of RNPs released from virions shows them capable of forming

169 Studying the in vitro responses of RNPs to microtubule-associated proteins (MAPs) and micro

170 Despite the central role of RNPs during infection, the factors dictating where and w

171 consistent with a model in which subsets of RNPs include mRNA and protein products from the same gen

172 Visualization of RNPs by atomic force microscopy indicated that the RNA i

173 ional heterogeneity and yielding insights on RNP assembly.

174 fferences appear to be tuned to their RNA or RNP substrates and their specific roles.

175 s numerous dynamic membrane-less organelles, RNP granules, enriched in RNA and RNA-binding proteins c

176 ACA proteins, but other eukaryotes use other RNP assembly pathways.

177 t of satBaMV via the fibrillarin-satBaMV-P20 RNP complex in phloem-mediated systemic trafficking.

178 sequestered in ribonucleoprotein particles (RNPs) and thus subjected to delayed translation.

179 A cargos of the ribonucleoprotein particles (RNPs) that form the substrate for axonal translation.

180 is packed into ribonucleoprotein particles (RNPs) where RNA binding proteins ensure mRNA silencing a

181 tion machinery, ribonucleoprotein particles (RNPs), and stress granules.

182 n ribosomal and ribonucleoprotein particles (RNPs), indicating a translational role in virus particle

183 sembly of H/ACA ribonucleoprotein particles (RNPs).

184 , RNAs exist as ribonucleoprotein particles (RNPs).

185 RNA and form L1-ribonucleoprotein particles (RNPs).

186 tivity rather than its total copy number per RNP, responsible for this effect.

187 gradients of polarity proteins can position RNP granules during development by using RNA competition

188 ge of patients with an increase in posterior RNP from baseline at months 30 and 36, whereas the 2 ran

189 patients who showed an increase in posterior RNP from baseline increased over time in all 3 groups, b

190 The percentage of patients with no posterior RNP decreased in the sham group between baseline and mon

191 s findings that the loosely packed precursor RNP undergoes a dramatic conformational change as it com

192 ng polymerase maturation into active progeny RNPs.

193 urprisingly, polyadenylation factors promote RNP coassembly in vivo, suggesting new functions of poly

194 granules are non-membrane bound RNA-protein (RNP) assemblies that form when translation initiation is

195 RNA structures and facilitating RNA-protein (RNP) complex assembly in vivo.

196 Cellular RNA-protein (RNP) granules are ubiquitous and have fundamental roles

197 RNA-protein (RNP) granules have been proposed to assemble by forming

198 nism for assembling liquid-like RNA/protein (RNP) bodies and other membrane-less organelles.

199 otein kinase C (PKC) family members regulate RNP assembly.

200 fluenza virus exploits host PKCs to regulate RNP assembly, a step required for the transition from pr

201 Here, we show that regulated RNP factor interactions drive transitions among diffuse,

202 Consistent with its role in regulating RNP assembly, knockout of PKCdelta impairs virus infecti

203 the widespread existence of auto-regulatory RNPs.

204 nts defective for the formation of a related RNP complex, the Processing body.

205 Confirming previous reports, RNPs with N truncations lacking the carboxyl-terminal 43

206 liquid-like phase-separated state resembling RNP granules.

207 to be surface-exposed significantly restores RNP bioactivity.

208 Ribonucleoprotein (RNP) granules are enriched in specific RNAs and RNA-bind

209 tivity of all possible 16 ribonucleoprotein (RNP) complexes (PB2, PB1, PA, NP) between CIV-H3N2 and p

210 ase holoenzyme contains a ribonucleoprotein (RNP) catalytic core and additional proteins that modulat

211 nomes when delivered as a ribonucleoprotein (RNP) complex.

212 dent on RNA structure and ribonucleoprotein (RNP) complex formation.

213 eting functional RNAs and ribonucleoprotein (RNP) complexes to genomic loci.

214 promote RNA cleavage and ribonucleoprotein (RNP) removal.

215 o mediate aspects of anti-ribonucleoprotein (RNP) autoimmunity, and are a potential target of therapy

216 V RNA appears to exist as ribonucleoprotein (RNP) complex composed of P20 and fibrillarin, whereas Ba

217 deliver BE3 and HF-BE3 as ribonucleoprotein (RNP) complexes into mammalian cells, establishing DNA-fr

218 ding RNAs best studied as ribonucleoprotein (RNP) guides in RNA modification.

219 anscriptionally assembled ribonucleoprotein (RNP) complexes.

220 llowing injection of Cas9 ribonucleoprotein (RNP) complexes in the hippocampus, striatum and cortex.

221 ciates with the condensed ribonucleoprotein (RNP) complex.

222 ing of the grk-containing ribonucleoprotein (RNP) complexes once they have reached their destination

223 shows that the Evf2-DLX1 ribonucleoprotein (RNP) contains the SWI/SNF-related chromatin remodelers B

224 apsid protein (N) to form ribonucleoprotein (RNP) complexes that are substrates for RNA synthesis and

225 pressor Nanos (Nos) forms ribonucleoprotein (RNP) particles that are dendritically localized in Droso

226 ough its participation in ribonucleoprotein (RNP) complexes for splice-site recognition, branch-point

227 Intracellular ribonucleoprotein (RNP) granules are membrane-less droplet organelles that

228 VLPs) in intracytoplasmic ribonucleoprotein (RNP) complexes.

229 re, affinity-purified MRP ribonucleoprotein (RNP) from HeLa cells cleaves the human pre-rRNA in vitro

230 which qualify as neuronal ribonucleoprotein (RNP) granules and concentrate multivalent proteins and m

231 identified nonmembranous ribonucleoprotein (RNP) granules.

232 modulate the presence of ribonucleoprotein (RNP) complexes in SGs are poorly understood.

233 n is an efficient RNA- or ribonucleoprotein (RNP)-based delivery method for the CRISPR-Cas system, wi

234 The nucleolus and other ribonucleoprotein (RNP) bodies are membrane-less organelles that appear to

235 They trap other ribonucleoprotein (RNP) granule components and disrupt RNP granule function

236 elivery of Cas9-guide RNA ribonucleoprotein (RNP) complexes.

237 The stable ribonucleoprotein (RNP) complex formed between the Lactococcus lactis group

238 ometry of a multi-subunit ribonucleoprotein (RNP) complex assembled in a solution containing Mg(2+).

239 Telomerase is the ribonucleoprotein (RNP) enzyme that elongates telomeric DNA to compensate f

240 rotein (M), M2-1, and the ribonucleoprotein (RNP).

241 ates of proteins underlie ribonucleoprotein (RNP) granules and nuclear RNA-binding protein assemblies

242 lizing a yet unidentified ribonucleoprotein (RNP) complex that is critical to the specificity of thes

243 condensation of the viral ribonucleoprotein (RNP) core with the matrix protein (M) during budding fro

244 interacts with the viral ribonucleoprotein (RNP) in a putative priming stage; at this stage, the int

245 Accordingly, viral ribonucleoprotein (RNP) reconstitution assays show that a viral polymerase

246 How and where ribonucleoprotein (RNP) transport granules that support this synthetic acti

247 Ribonucleoproteins (RNPs) can form liquid or solid aggregates, but control a

248 Ribonucleoproteins (RNPs) often coassemble into supramolecular bodies with r

249 ctively called EVs), and ribonucleoproteins (RNPs).

250 Cas9 system delivered as ribonucleoproteins (RNPs).

251 ociated with cytoplasmic ribonucleoproteins (RNPs) containing the RNA-binding protein Imp.

252 Such ribonucleoproteins (RNPs) can facilitate the high-fidelity introduction of s

253 anner and stabilized the ribonucleoproteins (RNPs) with a family of polypeptides bearing different ar

254 roup II introns into a dynamic, protein-rich RNP machinery.

255 Several RNP body regulators repress translation of mRNA subsets,

256 li, consistent with the role of CBs in small RNP assembly.

257 Eukaryotic box C/D small nucleolar (sno)RNPs catalyse the site-specific 2-O-methylation of ribos

258 are mostly mediated by small nucleolar (sno)RNPs during ribosome production.

259 Cell type-dependent expression of specific RNP types with distinct mRNA cargos, such as FXGs, prese

260 g filamentous nucleocapsid-helix structures (RNPs).

261 However, many such RNP bodies contain internal subcompartments, and the mec

262 he endogenous levels of the human telomerase RNP and its two key components, human telomerase RNA (hT

263 eate RNP granules, we further establish that RNP granule formation does not depend on amyloid-like ag

264 orly understood, one reason for this is that RNP granule purification has not yet been achieved.

265 We report that RNP granule formation is associated with increased neuri

266 We show that RNP granule formation leads to a >30-fold increase in th

267 The RNP complexes contain proteins and mRNAs involved in RNA

268 The RNP core comprises the negative-sense genomic RNA comple

269 ulate tandem repeat synthesis and bridge the RNP catalytic core, Teb1, and the p75 subunit of the hol

270 interactions with multiple host factors, the RNP subunits play vital roles in replication, host adapt

271 positions in the RNA remained dynamic in the RNP.

272 ther, our data provide new insights into the RNP rearrangements and extensive exchange of proteins th

273 al proteins that modulate the ability of the RNP catalytic core to elongate telomeres.

274 ting that ATP may promote disassembly of the RNP complex.

275 esents one-turn in the building block of the RNP helices.

276 in turn has limited the capabilities of the RNP-mediated genome editing toolbox.

277 mation of conical cores, suggesting that the RNP helps drive conical core assembly.

278 th a small CA sheet that associates with the RNP to form the core base, followed by polymerization of

279 hts into the quaternary arrangement of these RNP complexes in solution, an important step to understa

280 th the RNA and protein compositions of these RNP complexes.

281 g an essential role in the assembly of these RNP granules.

282 gates, but control and consequences of these RNP states in living, developing tissue are poorly under

283 e similarities, the data indicate that these RNP complexes are independently assembled and that this

284 These RNPs, consisting of approximately 2,600 protomers of nuc

285 Neither the structures of these RNPs nor the RNA features required to form them have bee

286 mal RNP and visualized the structure of this RNP using atomic force microscopy.

287 oupled with RNA binding, could contribute to RNP granule assembly in vivo through promoting phase sep

288 ch shifts the factors to the non-translating RNP fraction and is consistent with membrane association

289 p4 interacts with the functionally active U3 RNP; this particle, called the small-subunit (SSU) proce

290 helicase segregated a Prp3-Prp31-Snu13-U4/U6 RNP into an intact Prp31-Snu13-U4 snRNA particle, free P

291 ndensed phases driven by the IDRs of various RNP body proteins, including FUS, DDX4, and HNRNPA1.

292 essed as part of a biologically active viral RNP.

293 P-RNA complex is the building block of viral RNP.

294 y ribonucleoprotein (cRNP) and progeny viral RNP (vRNP) synthesis.

295 the primary target of nucleozin is the viral RNP, not NP, and this work also provides proof of the pr

296 , leading to IFN gene expression after viral RNPs (vRNPs) are released into the cytosol and are recog

297 PB1, and PA genomic RNAs suggests that viral RNPs are susceptible to cleavage by RNase L.

298 lasmic RNP granules in axon terminals, where RNP granules regulate local RNA metabolism and translati

299 ro at at least one site used in cells, while RNP isolated from cells with CRISPR-edited MRP loci lose

300 er proteins that sequester these ends within RNPs, and with end modification pathways that protect th