ライフサイエンスコーパス: RPL10

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1 r MSCI-mediated transcriptional silencing of Rpl10.

2 elix 95 region being adjacent to the protein Rpl10.

3 nexpected and may suggest a nuclear role for Rpl10.

4 PL10s differentially contribute to the total RPL10 activity in the male gametophyte.

5 understand the molecular interaction between Rpl10 and Nmd3.

6 Yeast Rpl10 belongs to the L10e family of ribosomal proteins.

7 Mutations in LSG1 or RPL10 blocked Nmd3-GFP shuttling into the nucleus and ex

8 ion of RPL10L prevents the death of cultured RPL10-deficient somatic cells, and Rpl10l-promoter-drive

9 ated that Arabidopsis (Arabidopsis thaliana) RPL10 genes are involved in development and translation

10 tions in the nucleus have been described for RPL10 in different organisms.

11 10l-promoter-driven transgenic expression of Rpl10 in spermatocytes restores spermatogenesis and fert

12 ating intersubunit rotation originating from rpL10 in the core of the large subunit (LSU) through bot

13 oop in the essential yeast ribosomal protein rpL10 is a central controller of this process.

14 In the large (60 S) subunit, Rpl10 is positioned in a cleft between the central protu

15 We have shown previously that Rpl10 is required for the release of the Crm1-dependent

16 The RIBOSOMAL PROTEIN L10 (RPL10) is an integral component of the eukaryotic riboso

17 es transcription of a ribosomal protein L10 (Rpl10)-like gene and the cell cycle inhibitor p27, and i

18 The rpL10 loop is also involved in Sdo1p recruitment, sugges

19 tural and biochemical effects, suppressed an rpL10 mutant, re-establishing rotational equilibrium.

20 e three AtRPL10 genes can complement a yeast RPL10 mutant.

21 Moreover, the characterization of double rpl10 mutants indicates that the three AtRPL10s differen

22 ing that the block in 60S export in lsg1 and rpl10 mutants results indirectly from failing to recycle

23 and the block in 60S export in both lsg1 and rpl10 mutants was also suppressed by mutant Nmd3 protein

24 ystal and solution structures of prokaryotic Rpl10 orthologs.

25 the dominant LSG1 mutant also traps a mutant Rpl10 protein that does not normally bind stably to the

26 new evidence about the nonredundant roles of RPL10 proteins in Arabidopsis.

27 We also found that mutant Rpl10 proteins were engineered to be unable to bind to t

28 Here, this paradox is explored using the rpL10-R98S (uL16-R98S) mutant yeast model of the most co

29 In this paper, we show that a loop of Rpl10 that embraces the P-site transfer ribonucleic acid

30 ried out an extensive mutational analysis of Rpl10 to identify mutations that would allow us to map a

31 nd translocation of the downstream component RPL10 to the nucleus, where it interacts with a newly id

32 pl10l expression compensates for the lack of Rpl10, which exhibits a broad expression pattern but is

33 y of Rpl10l, a murine autosomal retrogene of Rpl10 with testis-specific expression, disturbs ribosome

34 p is not necessary for stable interaction of Rpl10 with the ribosome, suggesting that it plays a dyna

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