ライフサイエンスコーパス: RPP

1 RPP correction did not improve reproducibility for eithe

2 RPP microarrays were used to profile the phosphorylation

3 RPP microarrays, prepared using simple procedures and st

4 RPP was effective only when it was added before assembly

5 e archaeal RPR is associated with at least 4 RPPs, which function in pairs (RPP21-RPP29 and RPP30-POP

6 DCA did not affect RPP but normalized dP/dt in HYP.

7 therapy had significantly lower BP, HR, and RPP at 5 and 7 metabolic equivalents (METs) and peak exe

8 Significantly lower exercise BP, HR, and RPP levels are achieved with beta-blocker-based therapy

9 plasma membrane proteins per 5 minutes, and RPP suppressed 50% of production.

10 n of 34.6 +/- 2.77 nanomoles superoxide, and RPP inhibited 60% of production.

11 The four archaeal RPPs have eukaryotic homologs and function as heterodime

12 leavage results from the ability of archaeal RPPs to selectively increase the RPR's apparent rate of

13 tively, these results indicate that archaeal RPPs are able to compensate for structural defects in th

14 ing our previous finding that these archaeal RPPs function as two binary RPP complexes (POP5*RPP30 an

15 eriolar diameter decreased by 17% and 29% at RPP of 130 and 160 mmHg, respectively.

16 ap of this binary complex with the bacterial RPP and highlights their shared recognition of a phyloge

17 Moreover, POP5*RPP30, like the bacterial RPP, helps normalize the RPR's rates of cleavage of non-

18 air (RPP21-RPP29) had no effect; both binary RPP complexes significantly reduced the monovalent and d

19 t these archaeal RPPs function as two binary RPP complexes (POP5*RPP30 and RPP21*RPP29), we prepared

20 roxide, and production was suppressed 72% by RPP.

21 he possible inhibition of this activation by RPP.

22 RPR function might imply that their cognate RPPs provide the functional groups that make up the acti

23 ts on resistance mediated by seven different RPP (recognition of Peronospora parasitica) genes.

24 After stimulation with the HLA-B*0702/EBV(RPP) peptide, the production of IL-2, perforin, and gran

25 However, the magnitude of the HLA-B*0702/EBV(RPP)-specific and HLA-B*0702/CMV(TPR)-specific CD8(+) T

26 revalence of MS patients with HLA-B*0702/EBV(RPP)-specific CD8(+) T cells ex vivo.

27 yme B and the cytotoxicity of HLA-B*0702/EBV(RPP)-specific CD8(+) T cells were decreased.

28 nse mutants on resistance specified by eight RPP genes (for resistance to Peronospora parasitica) exp

29 artially ameliorated upon addition of either RPP pair.

30 ion compared with placebo and controlled for RPP was reduced by 22.3% on ranolazine 500 mg bid (p = 0

31 Current models for RPP action are derived from 7.2- to 16-A resolution stru

32 l RNase P comprises an RPR and at least four RPPs, which have eukaryal homologs and function as two b

33 omprises one catalytic RPR and at least four RPPs.

34 Despite substantially greater RPP increases relative to baseline during beta1-AR (HCF,

35 is increased by the hypoxia-induced fall in RPP rather than by an increase in renal sympathetic acti

36 hypoxia is predominantly due to the fall in RPP.

37 gulatory responses induced by an increase in RPP, and this response was not further impaired by papil

38 r breathing were mediated by the increase in RPP; neither plasma ANP nor renin activity change in the

39 Cold pressor test increased RPP similarly in both groups (53+/-26% versus 46+/-26%),

40 The increased RPP to the right kidney accounted for differences in ren

41 acterial pathogens than it is to other known RPP genes.

42 (beta1, 39%; beta2, 34%), despite the large RPP difference between the groups.

43 1,183 +/- 1857 mm Hg/min; 75.5 +/- 12.9 min, RPP and heart rate, respectively; systolic blood pressur

44 Hg/min; 151 +/- 19.1 mm Hg; 197 +/- 8.6 min; RPP, systolic blood pressure and heart rate, respectivel

45 Moreover, one pair of Mja RPPs (POP5-RPP30) enhanced k(obs) for the RPR-catalyzed

46 ction was estimated by adding 0.20 microg/ml RPP.

47 coincubated with and without 0.25 microg/ml RPP.

48 We first show the application of RPP microarrays to the study of signaling kinetics and p

49 We conclude that elevations of RPP contribute significantly to the fibrosis and epithel

50 ogen gene expression; (b) acute reduction of RPP for 3 h could stimulate renin gene expression in the

51 Reduction of RPP to 60 mmHg for 3 h in these animals had little effec

52 se-urethane anaesthetised rats, reduction of RPP to 60 mmHg for 3 h in vehicle or losartan-treated (5

53 Following reduction of RPP to 60 mmHg for 3 h, plasma renin activity was increa

54 not apparent during short-term reduction of RPP.

55 current model for the mechanism of action of RPPs proposes that drug release is indirect and achieved

56 d from 7.2- to 16-A resolution structures of RPPs bound to vacant or nontranslating ribosomes.

57 l than the minor reductions in heart rate or RPP, suggesting that ranolazine's beneficial mechanism o

58 y the recognition of Peronospora parasitica (RPP)2 (At) locus in Arabidopsis accession Columbia (Col-

59 ance (Recognition of Peronospora parasitica [RPP]) gene products triggers localized cell death (a hyp

60 ctions are studied by Real Physical Picture (RPP) model.

61 espite significant progress in cloning plant RPP genes and characterizing essential plant components

62 ent basal MABP and renal perfusion pressure (RPP) from falling after addition of Losartan and to keep

63 died the impact of renal perfusion pressure (RPP) on the development of renal injury in this model.

64 influence of acute renal perfusion pressure (RPP) reduction on renin release, renal renin and angiote

65 V were absent when renal perfusion pressure (RPP) was prevented from rising during air breathing by u

66 step increases in renal perfusion pressure (RPP).

67 Baseline rate-pressure product (RPP) (6559+/-1590 versus 7144+/-1157 bpmxmm Hg) and MBF

68 % to 26% reduction in rate pressure product (RPP) and impaired dP/dt versus SHAM (P<0.05).

69 , heart rate (HR) and rate-pressure product (RPP) at maximal and submaximal workloads were assessed.

70 nt depression and the rate-pressure product (RPP) during exercise to determine whether ranolazine's m

71 similar increases in rate-pressure product (RPP) in smokers and nonsmokers.

72 5 and 5 minutes for a rate-pressure product (RPP) less than 20% baseline.

73 lso normalized to the rate.pressure product (RPP).

74 ventricular systolic blood pressure product (RPP).

75 urements were made of rate-pressure product (RPP=LV developed pressure x heart rate), phosphorus-cont

76 ly downregulated by an RPE-generated protein RPP.

77 The bacterial RNase P protein (RPP) aids RNase P RNA (RPR) catalysis by promoting subst

78 c RNase P RNA (RPR) and one RNase P protein (RPP), have helped understand the pleiotropic roles (incl

79 veloped a multiplexed reverse phase protein (RPP) microarray platform for simultaneous monitoring of

80 tinal pigment epithelial protective protein (RPP) was described, which suppresses the superoxide gene

81 R) and a varying number of RNase P proteins (RPPs): 1 in bacteria, at least 4 in archaea and 9 in euk

82 Ribosome protection proteins (RPPs) confer resistance to tetracycline by binding to th

83 Ribosome protection proteins (RPPs) confer tetracycline resistance by binding to the r

84 Robustified projection pursuit (RPP) was used for statistical analysis using RNA as a su

85 method using robustified projection pursuit (RPP).

86 30 and RPP21*RPP29), we prepared recombinant RPP pairs from three archaea and established interchange

87 the "Trp-cage" peptide (NLY IQW LKD GGP SSG RPP PS).

88 ne essential RNA (RPR) and protein subunits (RPPs) numbering one in bacteria, and at least four in ar

89 ver, the number of RNase P protein subunits (RPPs) varies from 1 in bacteria to 9 or 10 in eukarya.

90 nucleotide C1054 of the 16S rRNA, such that RPP action uses Pro509, rather than Y506/Y507, to direct

91 The RPP and ST-segment depression were assessed before start

92 ectively), despite comparable changes in the RPP (P = NS).

93 ercise despite an additional increase in the RPP.

94 yo-electron microscopy reconstruction of the RPP TetM in complex with a translating ribosome at 3.9-A

95 Here we report a cryo-EM structure of the RPP TetM in complex with the 70S ribosome at 7.2-A resol

96 rug-binding site induced upon binding of the RPP to the ribosome.

97 d it had weak-to-intermediate effects on the RPP genes.

98 renal arteries; during the same period, the RPP to the right kidney rose to 164 +/- 8 mmHg.

99 MBF normalized to the RPP (derived from the ratio of MBF ([milliliters per gra

100 of salt-induced hypertension over 2 wk, the RPP to the left kidney was maintained at control levels

101 t necessary for resistance mediated by these RPP genes.

102 1-2/ndr1-1 background, suggesting that these RPP genes operate additively through EDS1, NDR1 and as-y

103 bidopsis genes following activation of three RPP genes directed against the pathogenic oomycete Peron

104 of MBF ([milliliters per gram per minute] to RPP [beats per minute times millimeters of mercury] time

105 WT control mice exhibited typical RPP-dependent vasoconstriction that was significantly at

106 n groups (48+/-36% versus 48+/-28%), whereas RPP again increased similarly in the 2 groups (59+/-30%