ライフサイエンスコーパス: Rad51 recombinase

1 the beta-isoform of BCCIP in relation to the RAD51 recombinase.

2 ated DNA synthesis from a D-loop made by the Rad51 recombinase.

3 s recombination (HR), where it regulates the RAD51 recombinase.

4 sis of DNA double strand break repair by the Rad51 recombinase.

5 s recombination requires the function of the RAD51 recombinase.

6 duct and examining its interactions with the Rad51 recombinase.

7 gle-stranded DNA and (ii) stimulation of the RAD51 recombinase.

8 d repair, presumably in conjunction with the Rad51 recombinase.

9 shown here to promote D-loop formation with Rad51 recombinase.

10 ed Pir51, that strongly interacts with human Rad51 recombinase.

11 n vivo, HsRad54 protein interacts with human Rad51 recombinase.

12 erlapping chromosomal foci with the DMC1 and RAD51 recombinases.

13 es of both the bacterial RecA and eukaryotic Rad51 recombinases.

14 The Rad51 recombinase, a member of the RAD52 group of recomb

15 Thus, Rad52 functions as a co-factor for the Rad51 recombinase, acting specifically to overcome the a

16 trated that Y54 phosphorylation enhances the RAD51 recombinase activity by at least two different mec

17 homologous recombination (HR) by regulating RAD51 recombinase activity.

18 , XRCC2, and XRCC3) that share homology with RAD51 recombinase and are known as the RAD51 paralogs ar

19 and the functional interactions of PCNA with Rad51 recombinase and DNA polymerase (Pol) delta, Pol et

20 s to demonstrate that human RECQL5 binds the Rad51 recombinase and inhibits Rad51-mediated D-loop for

21 s at DNA damage sites concomitantly with the RAD51 recombinase and is retained after RAD51 disassembl

22 function through interactions with the human Rad51 recombinase and play a crucial role in the homolog

23 rtantly, Rdh54 physically interacts with the Rad51 recombinase and promotes D-loop formation by the l

24 Moreover, we find that poleta interacts with RAD51 recombinase and RAD51 stimulates poleta-mediated D

25 BRCA2 protein interacts directly with the RAD51 recombinase and regulates recombination-mediated D

26 oreover, Rad52 physically interacts with the Rad51 recombinase and serves as a mediator in the Rad51-

27 avelled, in that key HR proteins such as the RAD51 recombinase and the tumour suppressors BRCA1 and B

28 al accessory protein that interacts with the RAD51 recombinase and this interaction fluctuates during

29 4 (PTD4)], inhibited subnuclear assembly of RAD51 recombinase, and sensitized Chinese hamster ovary

30 BLM is known to form a complex with the RAD51 recombinase, and to act upon DNA intermediates tha

31 recombination (HR) reactions mediated by the RAD51 recombinase are essential for DNA and replication

32 tional repair of double-stranded DNA breaks, RAD51 recombinase assembles as a nucleoprotein filament

33 The Rad51 recombinase assembles on DNA to execute homologous

34 recombination (HR); assisting the loading of RAD51 recombinase at DNA double-strand breaks.

35 n cancer cells, phosphorylates the essential Rad51 recombinase at serine 14 (S14) during the cell cyc

36 sDNA from replication protein A (RPA) to the RAD51 recombinase during DNA break and replication fork

37 Homologous DNA recombination (HR) by the RAD51 recombinase enables error-free DNA break repair.

38 AD51AP1 helps maintain genomic integrity via RAD51 recombinase enhancement.

39 The RAD51 recombinase facilitates DNA joint formation during

40 s recombination relies on the formation of a Rad51 recombinase filament that forms on single-stranded

41 st likely through an ability to displace the Rad51 recombinase from DNA.

42 pacity, and a co-dominant-negative effect on RAD51 recombinase function.

43 Yeast Rad51 recombinase has only minimal ability to form D loo

44 Removing Rhp51, the Rad51 recombinase homologue, suppresses the slowing defe

45 is to supercoil DNA, and cooperates with the Rad51 recombinase in DNA joint formation.

46 cancer suppressor protein BRCA2 controls the RAD51 recombinase in reactions that lead to homologous D

47 ase activity and functions together with the Rad51 recombinase in the D-loop reaction.

48 The RAD51 recombinase interacts directly with the breast can

49 We report here that the Rad51 recombinase is cleaved in mammalian cells during t

50 re resected normally, but the loading of the RAD51 recombinase is defective.

51 Homologous recombination catalyzed by the RAD51 recombinase is essential for maintaining genome in

52 The human Rad51 recombinase is essential for the repair of double-

53 elicase activity and the ability to displace Rad51 recombinase, it was unclear which functions were r

54 -ABL1 (nonmutated and T315I mutant) promoted RAD51 recombinase-mediated unfaithful homeologous recomb

55 is a distinctive activity of Rad52; neither Rad51 recombinase nor the yeast Rad52 paralog Rad59 has

56 s homologous recombination by nucleating the Rad51 recombinase onto replication protein A-coated sing

57 The RAD51 recombinase plays a central role in homologous rec

58 e are two BIR pathways, one dependent on the Rad51 recombinase protein and one Rad51 independent; the

59 ess to identify the times for the loading of Rad51 recombinase protein onto the DSB ends at MAT, the

60 We wondered if Rad51 recombinase (Rad51), a factor that escorts replica

61 We propose that the Dmc1/Rad51 recombinases require Hop2 to distinguish homologou

62 is analysis between mutants defining Rrp1/2, Rad51 (recombinase), Swi5 and Rad57 (HR-mediators) plus

63 ns multiple copies of a motif that binds the Rad51 recombinase (the BRC repeat), and the C terminus c

64 ance of genome stability by interacting with RAD51 recombinase through its C-terminal domain.

65 e for Mek1 in inhibiting the activity of the Rad51 recombinase through phosphorylation of its binding

66 ase is known to dismantle nucleofilaments of Rad51 recombinase to prevent spurious recombination even

67 nd that it functions in conjunction with the Rad51 recombinase to repair damaged telomeres via the al

68 omologous recombination in eukaryotes is the RAD51 recombinase, which forms helical nucleoprotein fil