ライフサイエンスコーパス: Ramachandran

1 Ramachandran criticizes Trivers' conjecture, arguing tha

2 Ramachandran et al. argued that ICC neurons of types V,

3 Ramachandran scores and other geometric indicators show

4 nstrate that this sensitivity results from a Ramachandran dihedral psi angle dependent coupling of th

5 aint gives rise to inaccessible regions in a Ramachandran plot.

6 Like a Ramachandran plot, clusters of residues appear at discre

7 ll in the standard alpha-helical region of a Ramachandran plot.

8 A graph not unlike a Ramachandran plot is presented illustrating the various

9 es can be depicted graphically to provide a 'Ramachandran'-type view of RNA global structure that can

10 rowly into two specific regions of the L-Ala Ramachandran map.

11 e relationship between Raman frequencies and Ramachandran dihedral angles of the polypeptide backbone

12 -acids side-chain charges within a motif and Ramachandran plots for each residue.

13 simulated annealing, and chemical shift and Ramachandran refinement.

14 ve game in order to investigate Trivers' and Ramachandran's conjectures.

15 ctures, based upon empirical metrics such as Ramachandran geometries and chi(1)/chi(2) distributions,

16 s for a statistical mapping of the available Ramachandran space of each amino acid in terms of confor

17 tions and during the transit process between Ramachandran basins, e.g., from the beta to the alpha re

18 The populations and transitions between Ramachandran basins are studied for combinations of the

19 can be mapped in two dimensions, as shown by Ramachandran, Sasisekharan, and Ramakrishnan almost half

20 oups based on the clusters from the complete Ramachandran data: nonpolar/beta-branched (Ile and Val),

21 e angle sampling based on neighbor-dependent Ramachandran probability distributions.

22 a van der Waals energy function and derived Ramachandran plots for each of the amino acids.

23 The sets of NMR derived Ramachandran angles are assembled in a set of test struc

24 this increase to be the result of different Ramachandran angle values in certain residues of the Abe

25 We lastly postulate that these different Ramachandran angle values could possibly be traced to th

26 e further illuminated in three-dimensional, "Ramachandran-type" plots that relate D-B and B-A torsion

27 its time-dependent sequences of discretized Ramachandran basins occupied by successive backbone resi

28 utions of main chain (Phi,Psi) angles (i.e., Ramachandran maps) of the 20 naturally occurring amino a

29 approximated as hard spheres, the eponymous Ramachandran plot demonstrated that steric clashes alone

30 rs, identification of possible model errors, Ramachandran-style conformational maps and classificatio

31 final structures of the dimer had favorable Ramachandran angles and a root-mean-square deviation of

32 als alternate between left- and right-handed Ramachandran angles, which also justifies the need for c

33 cribed by conformational angles resulting in Ramachandran plots.

34 In this issue, Ramachandran et al. report that mutations in the gene en

35 affect a peptide's conformational landscape (Ramachandran space).

36 advanced knowledge of the very broad native Ramachandran basin assignments.

37 To ensure the precision of Ramachandran plot comparisons, we applied a rigorous Bay

38 leophilic residue into a forbidden region of Ramachandran space.

39 e alpha-helical and extended beta-regions of Ramachandran space.

40 A residue's complete transit from one Ramachandran basin to another, however, occurs in a mann

41 Polysaccharides distorted the peptide Ramachandran angles consistent with the circular dichroi

42 to correlate structure and observed potency, Ramachandran-type plots were calculated for a series of

43 nformations, which we used to estimate a Psi Ramachandran angle energy landscape.

44 mperature dependence of the peptide bond Psi Ramachandran angle population distribution of a 21-resid

45 a method to estimate the distribution of Psi Ramachandran angles for these conformations, which we us

46 and calculate the free energy along the Psi Ramachandran angle secondary folding coordinate.

47 ndence of the amide frequencies on their Psi Ramachandran angles and hydrogen bonding enables us, for

48 The Ramachandran angles for the title compound are obtained

49 The Ramachandran scores and the stereochemical quality of th

50 ative Gibbs free energy landscapes along the Ramachandran Psi-coordinate of a mainly poly-Ala peptide

51 lts on the conformational equilibria and the Ramachandran Psi angle (un)folding Gibbs free energy lan

52 Because the Ramachandran conformations of GlyB20 and GlyB23 are ordi

53 Finally, inspired by the Ramachandran plot, we developed a plot of Sm versus Em (

54 uently use this information to determine the Ramachandran torsion angles phi and psi.

55 We describe a new method to estimate the Ramachandran Psi-angular distributions from amide III ba

56 ctures and a considerable improvement in the Ramachandran map statistics.

57 e PPII and right-handed helix troughs in the Ramachandran plot, which is part of the very heterogeneo

58 ional Gaussian distribution functions in the Ramachandran space pertaining to subensembles of polypro

59 Like the Ramachandran plot, the eta-theta plot is a valuable syst

60 an force in the extended chain region of the Ramachandran diagram, which broadens as the temperature

61 Further analysis of the Ramachandran dihedral angles (phi, psi) reveals that the

62 la)(n) conformers in the P(II) region of the Ramachandran map.

63 about residue occupancy in any region of the Ramachandran map.

64 oline II region to the helical region of the Ramachandran map.

65 unhindered by the chiral restrictions of the Ramachandran plane.

66 dihedral angles lie in the right side of the Ramachandran plot (alpha(L) region; phi 97 degrees).

67 handed alpha-helical region (L-alpha) of the Ramachandran plot are a potential indicator of structura

68 es of amino acids in specific regions of the Ramachandran plot are preferred at the functional sites

69 many residues lie in the beta-region of the Ramachandran plot, and molecular-dynamics simulations co

70 ning the extended and helical regions of the Ramachandran plot, and they detect a predominant average

71 roline (PPII) and the helical regions of the Ramachandran plot.

72 of residues in the disallowed regions of the Ramachandran plot.

73 s possible within the allowed regions of the Ramachandran space with only minor mutations to a known

74 eta-structure, and PPII-helix regions of the Ramachandran surface and that they "flicker" between the

75 aluation of pseudotorsional space and of the Ramachandran-like eta-theta plot.

76 ued our development of methods to relate the Ramachandran Psi-angle to the amide III band frequency.

77 The obtained values are very close to the Ramachandran coordinates of the polyproline II helix (PP

78 rently reporting on backbone sampling within Ramachandran substates, while a slower component (5-25 n