ライフサイエンスコーパス: Reston

1 Texas, and the Philippines in 1996 (subtype Reston).

2 ines and Reston, Virginia, isolates [subtype Reston]).

3 es, Sudan and Cote d'Ivoire, as well as from Reston, a strain thought to be nonpathogenic in humans,

4 With the exception of Reston and Lloviu viruses, filoviruses (marburgviruses,

5 athepsin B, while the ebolaviruses Sudan and Reston and Marburg virus are not.

6 e differences in human pathogenicity between Reston and the other four ebolavirus species.

7 IgM capture assay detected anti-EBO (subtype Reston) antibodies in the sera of 5 of 5 experimentally

8 f a human who was infected with EBO (subtype Reston) during a postmortem examination of an infected m

9 mong the filoviruses characterized thus far, Reston Ebola virus (REBOV) is the only Ebola virus that

10 interaction, Zaire, mouse-adapted Zaire, and Reston Ebola virus VP24s displayed similar capacities to

11 The exception is the species Reston Ebola virus, which has not been associated with h

12 roteins from Zaire, mouse-adapted Zaire, and Reston Ebola viruses for interaction with all six member

13 brary against Zaire, Sudan, Ivory Coast, and Reston Ebola viruses.

14 The emergence of Reston ebolavirus (REBOV) in domestic swine in the Phili

15 ells infected with Zaire Ebolavirus (ZEBOV), Reston Ebolavirus (REBOV), and Marburgvirus (MARV), usin

16 e syndrome, have now been discovered to host Reston ebolavirus (REBOV).

17 us (EBOV), Bundibugyo ebolavirus (BDBV), and Reston ebolavirus (RESTV) belong to the same genus but e

18 raced back only within the last 50 years for Reston ebolavirus and Zaire ebolavirus species and sugge

19 re, but more slowly progressive illness; and Reston Ebolavirus caused mild disease that was late in o

20 divided into five distinct species, of which Reston ebolavirus is uniquely nonpathogenic to humans.

21 al structures of the dsRNA-binding domain of Reston ebolavirus VP35.

22 GP from Reston ebolavirus, a nonpathogenic species in humans, sh

23 Marburg marburgvirus, Tai Forest ebolavirus, Reston ebolavirus, Sudan ebolavirus, Zaire ebolavirus, a

24 0(-4) nucleotide substitutions/site/year for Reston ebolavirus.

25 are known: Zaire, Sudan, Cote d'Ivoire, and Reston ebolavirus.

26 la virus (subsequently identified as subtype Reston) infection among cynomolgus monkeys imported from

27 In April 1996, Ebola virus (subtype Reston) infection was identified in another group of cyn

28 equirements, put in place after the original Reston outbreak in 1989-1990, were effective for detecti

29 emented since the first Ebola virus (subtype Reston) outbreak appeared to work well.

30 thogenic in humans, apes, and monkeys, Ebola Reston (REBOV) is pathogenic only in monkeys.

31 Brassica napus (cultivar Reston) seed proteins were analyzed at 2, 3, 4, 5, and 6

32 GP derived from the Reston strain of virus, which causes disease in nonhuman

33 et of recombinant surface glycoproteins from Reston, Tai Forest, Bundibugyo, Zaire, Sudan, and Marbur

34 confocal microscope (Tandem Scanning Corp., Reston, VA).

35 [subtype Zaire] and the 1989 Philippines and Reston, Virginia, isolates [subtype Reston]).

36 ed conference on this topic that occurred in Reston, Virginia.

37 Ebola virus (EBOV) and Reston virus (RESTV) are members of the Ebolavirus genus

38 Both Ebola virus (EBOV) and Reston virus (RESTV) cause disease in nonhuman primates,

39 ns, ranging from asymptomatic infections for Reston virus (RESTV) to severe disease with fatal outcom

40 ndibugyo virus (BDBV), Tai Forest virus, and Reston virus (RESTV).

41 bolavirus genus, Bundibugyo virus (BDBV) and Reston virus (RESTV).

42 Herein we show that Ebola Reston virus glycoprotein (ResGP) is efficiently incorpo

43 rus, respectively and (iv) antibodies to the Reston virus GP for which no antibodies have been report

44 novel hosts, and only a few SDPs distinguish Reston virus VP24 from VP24 of other Ebolaviruses, human

45 c of an ebolavirus nonpathogenic for humans (Reston virus) and that of an ebolavirus with lower letha

46 n virus, Tai Forest virus, Bundibugyo virus, Reston virus, and Marburg virus and differentiated betwe

47 Since Reston virus, the only non-human pathogenic Ebolavirus s

48 a fascicularis) infected with Ebola (subtype Reston) virus in a US-registered quarantine facility.

49 Reston viruses are the only Ebolaviruses that are not pa

50 This is of concern since Reston viruses circulate in domestic pigs and can infect

51 ll nine Ebolavirus proteins that distinguish Reston viruses from the four human pathogenic Ebolavirus

52 VP24 of other Ebolaviruses, human pathogenic Reston viruses may emerge.

53 t react to the Ebola, Sudan, Bundibugyo, and Reston viruses.

54 ly neutralizes Ebola, Sudan, Bundibugyo, and Reston viruses.