ライフサイエンスコーパス: Rho GTPase-activating protein

1 tion by Y. pseudotuberculosis YopE, a potent Rho GTPase activating protein.

2 1, a kinesin-6 motor, and CYK-4/MgcRacGAP, a Rho GTPase-activating protein.

3 ssociation of intronic variants in ARHGAP15 (Rho GTPase-activating protein 15; rs4662344-T: P=1.9 x 1

4 that the cortical development gene Slit-Robo Rho GTPase-activating protein 2 (SRGAP2) duplicated thre

5 on control protein 42) and Srgap2 (SLIT-ROBO Rho GTPase-activating protein 2).

6 e 12 (MMP12)/MMP13, catenin alpha3 (CTNNA3), rho GTPase-activating protein 24 (ARHGAP24), angiopoieti

7 ll spreading through its interaction partner Rho GTPase-activating protein 29 (ArhGAP29), a GTPase ac

8 cating mutations in the terminal exon of the Rho GTPase-activating protein 31 gene, ARHGAP31, which e

9 nested within intron 1 of the gene encoding Rho GTPase activating protein 6 (ARHGAP6).

10 lated a putative mouse ortholog of the human Rho GTPase activating protein 8, ARHGAP8.

11 oxicity was demonstrated to be linked to its Rho GTPase activating protein activity.

12 on, migration, and proliferation through its Rho GTPase-activating protein activity and focal adhesio

13 Here, we demonstrate that the Rho-GTPase-activating protein alpha2-chimaerin is specif

14 f Pseudomonas aeruginosa that possesses both Rho GTPase-activating protein and ADP-ribosyltransferase

15 Deleted in Liver Cancer 1 (DLC1) encodes a Rho-GTPase activating protein and is a candidate 8p tumo

16 comprising the Cdc42-interactor IQGAP1, the Rho GTPase-activating protein ARHGAP10, and the integrin

17 3D spheroids of human cells, we identify the Rho GTPase activating protein ARHGAP18 as an effector of

18 emonstrated that selective expression of the Rho GTPase-activating protein ARHGAP42 in smooth muscle

19 (CaV2.2) were induced by TNF, whereas Vav2, Rho GTPase-activating protein, calcium channel voltage-d

20 hat through its domain structure, SRGAP2A, a Rho-GTPase-activating protein, can co-regulate excitator

21 Two related Rho GTPase-activating proteins, DLC-1 (deleted in liver

22 The Rho GTPase-activating protein DLC1 is a tumor suppressor

23 Residues 96 to 232 comprise a Rho GTPase activating protein domain, while residues 233

24 uronal diacylglycerol-binding protein with a Rho GTPase-activating protein domain that inactivates Ra

25 Homeostatic sleep control requires the Rho-GTPase-activating protein encoded by the crossveinle

26 ion of the actin cytoskeleton independent of Rho GTPase-activating protein function, and ExoT was sub

27 The N-terminus (residues 1-232) is a Rho GTPase activating protein (GAP) domain, while the C-

28 The N terminus possesses a Rho GTPase-activating protein (GAP) activity, whereas th

29 ends on interactions with CYK-4/MgcRacGAP, a Rho GTPase-activating protein (GAP) domain containing pr

30 we show that, contrary to expectations, the Rho GTPase-activating protein (GAP) domain of CYK-4 prom

31 ribosyltransferase domain and an N-terminal Rho GTPase-activating protein (GAP) domain.

32 interacts with the PDZ binding motif of the Rho GTPase-activating protein (GAP) Myosin-9A.

33 Deleted in Liver Cancer 1 (DLC1) is a RHO GTPase-activating protein (GAP) that negatively regu

34 One effector, YopE, functions as a Rho GTPase-activating protein (GAP).

35 f in the Src homology 3 (SH3) domain of p115 Rho GTPase-activating protein (GAP).

36 two-hybrid method, we identified a family of Rho GTPase-activating proteins (GAP) from Arabidopsis, t

37 Bem2p is a Rho-GTPase activating protein (GAP) previously shown to

38 The SYD-1 protein contains PDZ, C2 and rho-GTPase activating protein (GAP)-like domains, and is

39 P190A and p190B Rho GTPase activating proteins (GAPs) are essential gene

40 so present in the p190 family of cytoplasmic Rho GTPase activating proteins (GAPs).

41 ain of Robo interacts with a novel family of Rho GTPase activating proteins (GAPs).

42 ding proteins are subjected to regulation by Rho GTPase-activating proteins (GAPs) in the course of t

43 y which is further stimulated by a family of Rho GTPase-activating proteins (GAPs).

44 Here we show that ArhGAP30, a Rho GTPase-activating protein, is a pivotal regulator fo

45 These results suggest that a Rho GTPase-activating protein may have a positive input

46 with exception of the Crossveinless-c (Cv-c) Rho GTPase-activating protein, most effectors exert litt

47 ty defect of macrophages lacking the RhoGAP (Rho GTPase-activating protein) myosin IXb (Myo9b).

48 d that the Rho GTPase and its regulator p190 Rho-GTPase-activating protein (p190 RhoGAP) also play an

49 anism involves p120 catenin interaction with Rho GTPase activating protein (p190RhoGAP), leading to p

50 Rho GTPase activating proteins promote the intrinsic GTP

51 These include adaptor molecules (SOCS, Rho-GTPase activating protein, RAB35), kinases (MEK kina

52 Residues 96-232 comprise the Rho GTPase activating protein (Rho GAP) domain, whereas

53 Residues 96-233 comprise the Rho GTPase-activating protein (Rho GAP) domain, while re

54 (deleted in liver cancer 1), which encodes a Rho GTPase-activating protein (Rho-GAP), is a potent tum

55 AP3, a member of the Slit-Robo sub-family of Rho GTPase-activating proteins (Rho GAPs), controls acti

56 ends on its presence at focal adhesions, its Rho-GTPase activating protein (Rho-GAP) function, and it

57 Oligophrenin-1 (OPHN1) encodes a Rho-GTPase-activating protein (Rho-GAP) whose loss of fu

58 Oligophrenin-1 (OPHN1) encodes a Rho-GTPase-activating protein (Rho-GAP) whose loss of fu

59 neurons require Crossveinless-c, a specific Rho-GTPase-activating protein (Rho-Gap), to alter their

60 Genome-wide analyses of Rho GTPase activating protein (RhoGAP) function in Droso

61 in of Pseudomonas aeruginosa with N-terminal Rho GTPase-activating protein (RhoGAP) and C-terminal AD

62 DLC-1 encodes a Rho GTPase-activating protein (RhoGAP) and negative regu

63 9, and S567) in the DLC1 tumor suppressor, a Rho GTPase-activating protein (RhoGAP) associated with f

64 Residues 96-219 include the Rho GTPase-activating protein (RhoGAP) domain, and resid

65 p200 RhoGAP, a member of the Rho GTPase-activating protein (RhoGAP) family, was previ

66 Our laboratory isolated a novel rho GTPase-activating protein (rhoGAP) gene named ARHGAP

67 REN1 encodes a novel Rho GTPase-activating protein (RhoGAP) required for rest

68 The DLC1 gene encodes a Rho GTPase-activating protein (RhoGAP) that functions as

69 BPGAP1 is a Rho GTPase-activating protein (RhoGAP) that regulates ce

70 Activated Rac1 binds directly to p190B Rho GTPase-activating protein (RhoGAP), a major modulato

71 rmed cells, ERK5 induced the expression of a Rho GTPase-activating protein (RhoGAP), RhoGAP7/DLC-1, v

72 binding to Mg(2+), and k(cat) values of the Rho GTPase-activating protein (RhoGAP)-catalyzed reactio

73 cell, which might install platforms allowing Rho-GTPase-activating protein (RhoGAP) activity to be fo

74 gh Fog and RhoGEF2, but rather by inhibiting Rho GTPase activating proteins (RhoGAPs).

75 The Rho GTPase-activating proteins (RhoGAPs) are a family of

76 RHO GTPase-activating proteins (RHOGAPs) are one of the

77 GTP-bound RHO proteins are down-regulated by RHO GTPase-activating proteins (RHOGAPs).

78 eleted in liver cancer genes (DLC1-3) encode Rho-GTPase-activating proteins (RhoGAPs) whose expressio

79 e in vitro and in vivo, whereas mutations in rho-GTPase-activating protein showed the same phenotype

80 et genes, including Arhgap1, which encodes a RHO GTPase activating protein that was required for tumo

81 Here we report that oligophrenin-1, a Rho-GTPase activating protein that is absent in a family

82 at target the tumor suppressor gene DLC-1 (a Rho GTPase-activating protein), which is frequently dele

83 e have demonstrated that MEKK1 binds to p115 Rho GTPase-activating protein, which has GTPase-activati