ライフサイエンスコーパス: Rho guanine nucleotide exchange factor

1 in vivo by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor.

2 ther focal adhesion-associated proteins, and Rho guanine nucleotide exchange factors.

3 of G proteins, most prominently, G12/13, to Rho guanine nucleotide exchange factors.

4 within this family and between Vav and other Rho-guanine nucleotide exchange factors.

5 Rho guanine nucleotide exchange factor 11 (ARHGEF11), lo

6 ARHGEF11, which encodes the Rho guanine nucleotide exchange factor 11, was analyzed

7 ease (Capn1), protein kinase (Cdc42bpb), and Rho guanine nucleotide exchange factor 2 (Arhgef2) that

8 i2 and the Rho GTPase proteins Rhophilin and Rho guanine nucleotide exchange factor 3 (ARHGEF3).

9 Expression of ARHGEF4 (Rho guanine nucleotide exchange factor 4) is restricted

10 tment enhanced the protein expression of the Rho guanine nucleotide exchange factor ARHGEF1, MLC20 ,

11 An example is the Rho guanine nucleotide exchange factor, ARHGEF3, which w

12 ants, Plexin-B2 transgenic mice defective in Rho guanine nucleotide exchange factor binding are viabl

13 Vav1 is an hematopoietic-specific Rho guanine nucleotide exchange factor coupling tyrosine

14 teractions between endogenous GPR124 and the Rho guanine nucleotide exchange factors Elmo/Dock and in

15 complex formed of atypical and conventional Rho guanine nucleotide exchange factors for Rac and Cdc4

16 alian Trio is a multifunctional, multidomain Rho guanine nucleotide exchange factor (GEF) closely rel

17 or regulating the Wnt pathway: activity of a Rho guanine nucleotide exchange factor (GEF) encoded by

18 The Rho guanine nucleotide exchange factor (GEF) GEF-H1 cont

19 essed in COS-7 cells coprecipitates with the Rho guanine nucleotide exchange factor (GEF) Lbc.

20 aling a crucial role of the CD98hc/integrins/Rho guanine nucleotide exchange factor (GEF) leukemia-as

21 illin accumulation at the cleavage furrow is Rho guanine nucleotide exchange factor (GEF)(Pbl)-depend

22 LARG (leukemia-associated Rho guanine nucleotide exchange factor (GEF)), PDZ-RhoGE

23 Additionally, Rho guanine nucleotide exchange factor (GEF)-H1 transloc

24 ression inhibits Galpha12/13-, Galphaq-, and Rho guanine nucleotide exchange factor (GEF)-induced ser

25 The G-protein-mediated Rho guanine nucleotide exchange factor (GEF)-Rho GTPase

26 a(13) is increased by the N terminus of p115 Rho guanine nucleotide exchange factor (GEF).

27 udy, we show that son of sevenless 1 (SOS1), rho guanine nucleotide exchange factor (GEF)1 (ARHGEF1),

28 Rho is activated by members of the Rho guanine-nucleotide exchange factor (GEF) family; how

29 Here, we identified a homologue of Rho-guanine nucleotide exchange factor (GEF) in Caenorha

30 ators of Rho family small GTPases, pebble (a Rho guanine nucleotide exchange factor [GEF]) and RhoGAP

31 nalysis revealed that microtubule-associated Rho guanine nucleotide exchange factor, GEF-H1, particip

32 tudies, we placed Nod1 in a complex with the Rho-guanine nucleotide exchange factor Gef2.

33 Here, we identify the Vav family of Rho guanine nucleotide exchange factors (GEFs) as critic

34 Rho guanine nucleotide exchange factors (GEFs) compose a

35 AP12 and FcRgamma utilizes the Vav family of Rho guanine nucleotide exchange factors (GEFs) for proce

36 used a consensus sequence for Dbl domains of Rho guanine nucleotide exchange factors (GEFs) to search

37 Rho GTPases, activated by Rho guanine nucleotide exchange factors (GEFs), are cons

38 We show that Kalirin and Trio, homologous Rho guanine nucleotide exchange factors (GEFs), which in

39 ng protein and a member of the Dbl family of Rho guanine nucleotide exchange factors (GEFs).

40 The activation of Rho GTPases is governed by Rho guanine nucleotide exchange factors (GEFs).

41 In multicellular organisms, Rho-guanine nucleotide exchange factors (GEFs) and Rho G

42 are members of a newly identified family of Rho-guanine nucleotide exchange factors (GEFs) exhibitin

43 r phosphomimetic substitution did not affect Rho guanine nucleotide exchange factor, GTPase activatin

44 The Vav family of Rho guanine nucleotide exchange factors is thought to or

45 al7), a postsynaptic density (PSD)-localized Rho-guanine nucleotide exchange factor, is important for

46 ulated DC-SIGN signaling was mediated by the Rho guanine nucleotide-exchange factor LARG and led to i

47 Leukemia-associated Rho guanine nucleotide exchange factor (LARG) was origin

48 We have identified that leukemia-associated Rho guanine nucleotide exchange factor (LARG), also know

49 ator of RhoA activity is leukemia-associated Rho guanine nucleotide exchange factor (LARG).

50 Leukemia-associated Rho guanine-nucleotide exchange factor (LARG) belongs to

51 The leukemia-associated Rho-guanine nucleotide exchange factor (LARG) also assoc

52 Kalirin-7 (Kal7), a Rho guanine nucleotide exchange factor localized to the

53 ulence through activities such as mimicry of Rho guanine nucleotide exchange factors (Map and EspM),

54 Increasing evidence reveals that kalirin, a Rho-guanine nucleotide exchange factor, modulates PSD-95

55 pendent membrane recruitment of p115-RHOGEF (RHO guanine nucleotide exchange factor, molecular weight

56 There are a large number of Rho guanine nucleotide exchange factors, most of which h

57 Our data indicate that the Rho guanine nucleotide exchange factor Net1 binds to CAR

58 vity is dependent on an interaction with the Rho guanine nucleotide exchange factor p114RhoGEF but is

59 Galpha12 and Galpha13, are stimulated by the Rho guanine nucleotide exchange factor p115 RhoGEF.

60 The Rho guanine-nucleotide exchange factor p190RhoGEF (Rgnef

61 This remodeling required RHGF-1, a PDZ-Rho guanine nucleotide exchange factor (PDZ-RhoGEF) that

62 Rho guanine-nucleotide exchange factor (Pebble)-depleted

63 All Dbl family Rho guanine nucleotide exchange factors possess an invar

64 activation of RhoA through interaction with Rho guanine nucleotide exchange factor proteins.

65 INTERPRETATION: AKAP13 is a Rho guanine nucleotide exchange factor regulating activa

66 to the RGS-like (RGL) domain of a family of Rho guanine nucleotide exchange factors (RGL-RhoGEFs) th

67 exchanger) family (P-Rex1 and P-Rex2) of the Rho guanine nucleotide exchange factors (Rho GEFs) activ

68 Rho guanine nucleotide exchange factors (Rho GEFs) and R

69 Rho guanine nucleotide exchange factors (Rho GEFs) trans

70 ein kinase A (PKA) and D (PKD) and an active Rho-guanine nucleotide exchange factor (Rho-GEF) domain.

71 ents recruitment of both Plk1 itself and the Rho guanine nucleotide exchange factor (RhoGEF) Ect2 to

72 The Rho guanine nucleotide exchange factor (RhoGEF) Trio pro

73 Human ARHGEF11, a PDZ-domain-containing Rho guanine nucleotide exchange factor (RhoGEF), has bee

74 tains several signaling domains, including a rho-guanine nucleotide exchange factor (rhoGEF) domain a

75 gulator of G protein signaling homology (RH) Rho guanine nucleotide exchange factors (RhoGEFs) (p115R

76 re a mass spectrometric approach to identify Rho guanine nucleotide exchange factors (RhoGEFs) activa

77 s recently been demonstrated that Dbl family Rho guanine nucleotide exchange factors (RhoGEFs) can se

78 the phospholipase C (PLC)-beta isozymes and Rho guanine nucleotide exchange factors (RhoGEFs) relate

79 re known to directly activate three distinct rho guanine nucleotide exchange factors (rhoGEFs) that c

80 arrays form in response to prepatterning by Rho guanine nucleotide exchange factors (RhoGEFs), a fam

81 t the role of their upstream regulators, the Rho guanine nucleotide exchange factors (RhoGEFs).

82 ular effector enzymes, which include various Rho guanine nucleotide exchange factors (RhoGEFs).

83 Rho guanine-nucleotide exchange factors (RhoGEFs) activa

84 Net1 is a nuclear Rho guanine nucleotide exchange factor that is specific

85 Kalirin-7 (Kal7) is a Rho-guanine nucleotide exchange factor that is localized

86 Thus, Rho guanine nucleotide exchange factors, the activators

87 Moreover, upon clustering of ICAM-1, the Rho-guanine nucleotide exchange factor Trio activates Ra