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1 cytes, with proteins that negatively control Rous sarcoma oncogene cellular homolog (Src) activity.
2 at Y951 facilitates binding of VEGFR2 to the Rous sarcoma (Src) homology 2-domain of T cell-specific
3 totally unrelated late domain sequences from Rous sarcoma virus (contained in its p2b sequence) or eq
4 is virus integrase and bacterial recombinant Rous sarcoma virus (Prague A strain) integrase (approxim
5 resolution of a fragment of the integrase of Rous sarcoma virus (residues 49-286) containing both the
8 membrane binding, we fused the MA domains of Rous sarcoma virus (RSV) and HIV-1 to the chemically ind
9 the Gag protein; however, recent studies of Rous sarcoma virus (RSV) and human immunodeficiency viru
14 immunodeficiency virus type 1 (HIV-1) and of Rous sarcoma virus (RSV) are morphologically distinct wh
16 onducted to investigate the initial steps of Rous sarcoma virus (RSV) assembly by examining the assoc
20 d-state NMR (ssNMR) resonance assignments of Rous sarcoma virus (RSV) CA, assembled into hexamer tube
21 sembly incompetent by testing the ability of Rous sarcoma virus (RSV) CA-SP to assemble in vitro into
24 structure of the N-terminal domain (NTD) of Rous sarcoma virus (RSV) capsid protein (CA), with an up
26 an immunodeficiency virus type 1 (HIV-1) and Rous sarcoma virus (RSV) capsid proteins form a beta-hai
28 ence appears to be modular, as the unrelated Rous sarcoma virus (RSV) Env can be made Vpu sensitive b
30 this model, CA proteins from both HIV-1 and Rous sarcoma virus (RSV) form similar hexagonal lattices
31 We have identified an assembly-defective Rous sarcoma virus (RSV) Gag mutant that retains signifi
32 tudy in vitro-assembled, immature virus-like Rous sarcoma virus (RSV) Gag particles and have determin
39 of the NC domain in assembly of VLPs from a Rous sarcoma virus (RSV) Gag protein and have characteri
42 ously reported that nuclear transport of the Rous sarcoma virus (RSV) Gag protein is intrinsic to the
43 med spontaneously in vitro from fragments of Rous sarcoma virus (RSV) Gag protein purified after expr
44 ped three very small, modular regions of the Rous sarcoma virus (RSV) Gag protein that are necessary
48 een these two hypotheses, we made use of the Rous sarcoma virus (RSV) Gag protein, the PR of RSV IS i
51 eption was the 11-amino-acid p2b sequence of Rous sarcoma virus (RSV) Gag, which could fully restore
52 essential steps in understanding the chicken Rous sarcoma virus (RSV) genome association with a nonpe
53 elatively short, 82 nucleotide region of the Rous sarcoma virus (RSV) genome, called muPsi, was shown
56 t, the L domains of oncoretroviruses such as Rous sarcoma virus (RSV) have a more N-terminal location
58 Site-directed mutagenesis of recombinant Rous sarcoma virus (RSV) integrase (IN) allowed us to ga
59 nhanced when the serine at amino acid 124 of Rous sarcoma virus (RSV) integrase is replaced by alanin
62 we have examined whether the alpharetrovirus Rous sarcoma virus (RSV) is susceptible to inhibition by
63 proteins that specifically interact with the Rous sarcoma virus (RSV) L domain in vitro and in vivo.
65 taining the ts gene under the control of the Rous sarcoma virus (RSV) long terminal repeat (LTR) and
66 dogenous AAV promoters, p5 and p40, with the Rous sarcoma virus (RSV) long terminal repeat (LTR) and
67 eracts with the Schmidt-Ruppin strain of the Rous sarcoma virus (RSV) long terminal repeat (LTR) betw
70 CC-3' present on the noncoding strand of the Rous sarcoma virus (RSV) long terminal repeat (LTR) in a
71 eceptor (ecoR) cDNA under the control of the Rous sarcoma virus (RSV) long terminal repeat (LTR) prom
72 alovirus (CMV) immediate-early promoter, the Rous sarcoma virus (RSV) long terminal repeat, and the a
73 ts within the avian leukosis virus (ALV) and Rous sarcoma virus (RSV) LTR enhancers in a pattern iden
74 ssociation of HIV-1 Gag, as well as purified Rous sarcoma virus (RSV) MA and Gag, depends strongly on
75 in vitro flotation assay to directly measure Rous sarcoma virus (RSV) MA-membrane interaction in the
76 rted repeat (IR) within the U5 region of the Rous sarcoma virus (RSV) mRNA forms a structure composed
79 135-nucleotide (nt) direct repeats flank the Rous sarcoma virus (RSV) oncogene src and are composed o
80 virus-based vector LNCX, contain an internal Rous sarcoma virus (RSV) or cytomegalovirus (CMV) promot
81 ctivity compared with strong but nonspecific rous sarcoma virus (RSV) or cytomegalovirus promoters.
83 virus (EIAV) is functionally homologous with Rous sarcoma virus (RSV) p2b and human immunodeficiency
84 ent of Gag in in vivo and in vitro assembled Rous sarcoma virus (RSV) particles and to compare these
85 However, in the presence of budding HIV-1 or Rous sarcoma virus (RSV) particles, some glycoproteins,
87 mmunodeficiency virus type 1 (HIV-1) PTAP or Rous sarcoma virus (RSV) PPPY L domain in the p9 protein
88 t the enzymatic and structural properties of Rous sarcoma virus (RSV) PR are exquisitely sensitive to
89 pHyde gene under the control of a truncated Rous sarcoma virus (RSV) promoter (AdRSVpHyde) was gener
90 he cDNA for human iNOS was cloned behind the Rous sarcoma virus (RSV) promoter to create adenovirus (
94 enzyme, resulting in a highly active mutant Rous sarcoma virus (RSV) protease that displays many cha
95 ld be initiated by electroporation of cloned Rous sarcoma virus (RSV) proviral DNA into the developin
96 Expression of the Gag-Pol polyprotein of Rous sarcoma virus (RSV) requires a -1 ribosomal framesh
100 inding site in the 5' untranslated region of Rous sarcoma virus (RSV) RNA play an integral role in mu
101 ing element in the 3' untranslated region of Rous sarcoma virus (RSV) RNA was found to promote Rev-in
103 a mouse monoclonal antibody directed against Rous sarcoma virus (RSV) subgroup A Env that will be use
104 produce milligram quantities of the soluble Rous sarcoma virus (RSV) synaptic complex that is kineti
105 describes new mutations in the CA protein of Rous sarcoma virus (RSV) that were designed to test whet
106 In chick embryo fibroblasts transformed by Rous sarcoma virus (RSV) the tyrosine phosphorylation of
107 V), feline immunodeficiency virus (FIV), and Rous sarcoma virus (RSV) to critically address the role
109 ne transport, the multidomain Gag protein of Rous sarcoma virus (RSV) undergoes importin-mediated nuc
111 discovery from Ray Erikson's group that the Rous sarcoma virus (RSV) v-Src-transforming protein had
112 ol vector containing a constitutively active Rous sarcoma virus (RSV) viral promoter driving the luci
114 y reactions with purified CA proteins of the Rous sarcoma virus (RSV) were used to define factors tha
118 HIV-1, Moloney murine leukemia virus (MLV), Rous sarcoma virus (RSV), and human T-cell lymphotropic
119 human immunodeficiency virus type 1 (HIV-1), Rous sarcoma virus (RSV), and Mason-Pfizer monkey virus
120 articles of the prototypic avian retrovirus, Rous sarcoma virus (RSV), by using scanning transmission
122 ton Rous recovered a virus, now known as the Rous sarcoma virus (RSV), from a chicken sarcoma, which
124 osed based on the existence of MA mutants in Rous sarcoma virus (RSV), murine leukemia virus, human i
128 , a Gammaretrovirus, and the Alpharetrovirus Rous sarcoma virus (RSV), were susceptible to inhibition
129 eplication-competent shuttle vector based on Rous sarcoma virus (RSV), with alternate retroviral PPTs
130 the utility of the system, we developed new Rous sarcoma virus (RSV)-based replication-incompetent v
131 tween the PBS and the CA dinucleotide of the Rous sarcoma virus (RSV)-derived vector RSVP(A)Z to matc
132 the endogenous polypurine tract (PPT) of the Rous sarcoma virus (RSV)-derived vector RSVP(A)Z was rep
135 eplication-defective adenoviral vectors [Adv.Rous sarcoma virus (RSV)-nf] representing three families
136 vector encoding a peptide inhibitor of PKA [Rous sarcoma virus (RSV)-protein kinase A inhibitor (PKI
138 the robustly induced enzymatic activities in Rous sarcoma virus (RSV)-transformed chicken cells.
140 ng a well-established retroviral model-avian Rous sarcoma virus (RSV)-we analyzed changes in an RSV v
149 iruses containing the cellular receptors for Rous sarcoma virus (Tva) or ecotropic murine leukemia vi
151 chicken embryo fibroblasts (CEF) infected by Rous sarcoma virus against a confluent background of uni
152 roviruses that undergo type C morphogenesis, Rous sarcoma virus and human immunodeficiency virus, whi
154 s containing TATA and/or initiator elements, Rous sarcoma virus and thymidine kinase promoters in BeW
155 peat (DR) sequences flanking the src gene in Rous sarcoma virus are essential posttranscriptional con
156 e experiments reported here, using the avian Rous sarcoma virus as a model system, further define the
159 that allowed for the first-time formation of Rous sarcoma virus CA into structures resembling authent
162 of charged amino acids on the surface of the Rous sarcoma virus capsid protein in the assembly of app
163 ed sequence similarity, the structure of the Rous sarcoma virus capsid protein is similar to the stru
164 ences that exist in the C-terminal domain of Rous sarcoma virus capsid relative to the other capsid p
165 on of baby hamster kidney fibroblasts by the Rous sarcoma virus causes a significant increase in the
168 unodeficiency virus type 1, visna virus, and Rous sarcoma virus exhibited different target site prefe
169 o- deficiency virus type 1, visna virus, and Rous sarcoma virus exhibited distinct preferences for wa
170 here that while deletion of the NC domain of Rous sarcoma virus Gag abolishes formation and budding o
178 purified, slightly truncated version of the Rous sarcoma virus Gag protein, Delta MBD Delta PR, and
179 rescence correlation spectroscopy-to examine Rous sarcoma virus Gag-Gag and -membrane interactions in
180 gion, Mpsi, from the 5' leader region of the Rous sarcoma virus genome that is sufficient to direct t
182 0 amino acid residue capsid protein from the Rous sarcoma virus has been determined by NMR methods.
183 structure of the three-domain integrase from Rous sarcoma virus in complex with viral and target DNAs
184 contrast, CEF cultures heavily infected with Rous sarcoma virus in the same medium underwent pervasiv
185 plasmid acceptor, purified bacterium-derived Rous sarcoma virus integrase (IN), and a host cell DNA-b
186 ogous positions in visna virus integrase and Rous sarcoma virus integrase changed the target site pre
187 ous studies revealed that truncated forms of Rous sarcoma virus integrase containing two of the three
189 ct of the retroviral M domain from the avian Rous sarcoma virus is defined and its solution structure
192 binding chicken Y-box protein that promotes Rous sarcoma virus long terminal repeat (RSV LTR)-driven
193 ilar to the levels observed in vivo with the Rous sarcoma virus long terminal repeat constitutive pro
194 tained human factor IX (hFIX) cDNA driven by Rous sarcoma virus long terminal repeat in the E1 region
195 antibiotic-resistance gene was driven by the Rous sarcoma virus long terminal repeat or the herpes si
199 us, all of the functions associated with the Rous sarcoma virus MA sequence must be contained within
202 the site phosphorylated by gamma-PAK in the Rous sarcoma virus nucleocapsid protein NC in vivo and i
203 ngeable late assembly domains carried by the Rous sarcoma virus p2b protein and human immunodeficienc
205 er of cis-acting sequences within the RNA of Rous sarcoma virus play a role in preserving a large poo
207 coli lacZ reporter gene under control of the Rous sarcoma virus promoter and mammalian RNA processing
208 cloned into a pMAMneo vector containing the Rous sarcoma virus promoter and the neomycin resistance
209 r carrying the cDNA for C/EBPalpha driven by Rous sarcoma virus promoter elements (AdCEBPalpha) or a
210 which sig-mEndo expression was driven by the Rous sarcoma virus promoter had moderately high serum le
211 ls from the beta-galactosidase gene when the Rous sarcoma virus promoter is used to drive transgene e
212 riptional control of a constitutively active Rous sarcoma virus promoter was regulated identically to
214 as an inducible HIV-1 genome controlled by a Rous sarcoma virus promoter with lac operator sequences.
219 ervative substitutions in this region of the Rous sarcoma virus protein were lethal due to a severe d
226 e 3' splice site in the BPV-1 late pre-mRNA, Rous sarcoma virus src pre-mRNA, human immunodeficiency
227 As also found for other retroviruses, the Rous sarcoma virus structural protein Gag is necessary a
228 he negative regulator of splicing (NRS) from Rous sarcoma virus suppresses viral RNA splicing and is
229 ng (NRS) is a long cis-acting RNA element in Rous sarcoma virus that contributes to unspliced RNA acc
230 a mutant of the viral matrix (MA) protein of Rous sarcoma virus that disrupts viral RNA dimerization.
231 to as antisense, can inhibit replication of Rous sarcoma virus through hybridization to viral RNA.
235 natural or mutated 5' leader sequences from Rous sarcoma virus were expressed in avian cells in the
238 quenced a small segment of the 3' end of the Rous sarcoma virus, just inside the poly(A) tail, at the
239 of four promoters (dihydrofolate reductase, Rous sarcoma virus, long terminal repeat, or cytomegalov
243 gate Gag protein structure and processing in Rous sarcoma virus, the prototype of the avian sarcoma a
244 e used cryo-electron tomography to visualize Rous sarcoma virus, the prototypic alpharetrovirus.
245 e-bound nonreceptor tyrosine kinase Src from Rous sarcoma virus, these interactions are mediated by a
247 ses, including the prototypic oncoretrovirus Rous sarcoma virus, were synthesized on cytosolic riboso
249 We have constructed and characterized a Rous sarcoma virus-based retroviral vector with the host
251 is tyrosine-phosphorylated when expressed in Rous sarcoma virus-infected chicken embryo fibroblasts (
252 1 is shown to transcriptionally activate the Rous sarcoma virus-long terminal repeat promoter, which
253 nducible, constitutively expressed reporter, Rous sarcoma virus-luciferase (RSV-LUC); nor does it blo
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