ライフサイエンスコーパス: S. lugdunensis

1 S. lugdunensis binding to VWF, collagen, and endothelial

2 S. lugdunensis binds directly to VWF, which proved to be

3 S. lugdunensis is increasingly being recognized as a cau

4 S. lugdunensis is increasingly being recognized as a cau

5 S. lugdunensis IsdP was found to be iron regulated and c

6 S. lugdunensis may be an unrecognized yet infrequent cau

7 sis isolated in pure culture; 29 (94%) of 31 S. lugdunensis isolates were part of mixed nonpathogenic

8 identifying the reference strain and all 47 S. lugdunensis isolates without inappropriate amplificat

9 th antibiotics that may be effective against S. lugdunensis.

10 icaADBC homologues were found in all S. lugdunensis isolates tested, although the locus organ

11 ) of 500 isolates of CoNS were identified as S. lugdunensis.

12 itral valve endocarditis, were identified as S. lugdunensis.

13 osus, S. epidermidis, S. hominis, S. cohnii, S. lugdunensis, and S. haemolyticus, we identified an ap

14 say that is able to definitively distinguish S. lugdunensis from other staphylococci.

15 It remains unclear what factors enable S. lugdunensis to transition from a skin commensal to an

16 ion and the resulting release of VWF enabled S. lugdunensis to bind and colonize the heart valves.

17 he assay was both sensitive and specific for S. lugdunensis, correctly identifying the reference stra

18 ved between cadD and the cadB-like gene from S. lugdunensis, but no significant similarity was found

19 S. epidermidis, S. haemolyticus, S. hominis, S. lugdunensis, S. schleiferi, S. simulans, and S. warne

20 gether these findings offer insight into how S. lugdunensis fulfills its nutritional requirements whi

21 PNAG was not detected in S. lugdunensis extracts by immunoblotting with an anti-d

22 icaR was not detected in S. lugdunensis, but a novel open reading frame with puta

23 he genetic presence of icaADBC homologues in S. lugdunensis isolates, PNAG is not a major component o

24 hophysiologically relevant heme oxygenase in S. lugdunensis.

25 germ agglutinin showed a paucity of PNAG in S. lugdunensis biofilms, but abundant extracellular prot

26 To cause endovascular infections, S. lugdunensis requires mechanisms to overcome shear str

27 s species isolates (S. aureus, 211 isolates; S. lugdunensis, 3 isolates; and Staphylococcus spp., 444

28 In vivo adhesion of S. lugdunensis was evaluated in a mouse microvasculature

29 e laboratory and clinical characteristics of S. lugdunensis PJIs seen at the Mayo Clinic in Rochester

30 film formation properties of a collection of S. lugdunensis clinical isolates.

31 There were 28 episodes of S. lugdunensis PJIs in 22 patients; half of those patien

32 for the routine and timely identification of S. lugdunensis in the clinical microbiology laboratory.

33 se data indicate that nearly all isolates of S. lugdunensis are susceptible to narrow-spectrum antimi

34 wed to evaluate the clinical significance of S. lugdunensis isolation, the antimicrobial agents presc

35 Many types of S. lugdunensis infection, including native valve endocar

36 of the mesenteric circulation, VWF recruited S. lugdunensis to the vessel wall.

37 ining uncommon targets (e.g., Listeria spp., S. lugdunensis, vanB-positive Enterococci) were included

38 y to other coagulase-negative staphylococci, S. lugdunensis bound to VWF under flow, thus enabling it

39 Unique among the known Isd systems, S. lugdunensis contains a gene encoding a putative autol

40 es Staphylococcus aureus and CoNS other than S. lugdunensis and determines MecA-dependent resistance

41 In this study, we establish that S. lugdunensis expresses an iron-regulated IsdG-family h

42 hile invading host tissues and establish the S. lugdunensis Isd system as being involved in heme-iron

43 Our data suggest that the S. lugdunensis biofilm matrix contains proteinaceous fac

44 trains), for two Staphylococcus warneri, two S. lugdunensis, and two S. saprophyticus strains MICs we

45 In no case was S. lugdunensis isolated in pure culture; 29 (94%) of 31

46 The medical records of 62 patients from whom S. lugdunensis was isolated, including 31 penicillin-sus

47 This mechanism explains why S. lugdunensis causes more-aggressive infections, includ

48 face determinant (Isd) system encoded within S. lugdunensis.