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1 s, neurons cells from mice, and yeast cells (S. pombe).
2 plays a central role in zinc homeostasis in S. pombe.
3 d examining salt tolerance in sod2-deficient S. pombe.
4 activities between two different proteins in S. pombe.
5 confer salt tolerance when reintroduced into S. pombe.
6 sion yeasts Schizosaccharomyces kambucha and S. pombe.
7 ill be a valuable tool for future studies in S. pombe.
8 integrity and cellular stress resistance in S. pombe.
9 histone expression at the end of S phase in S. pombe.
10 quired for proper cell fate determination in S. pombe.
11 ences that contained 31% of the promoters of S. pombe.
12 en the CPC and the process of cytokinesis in S. pombe.
13 eb in mammals, and Tsc1/Tsc2 inhibit Rhb1 in S. pombe.
14 on similarly as an export carrier of mRNA in S. pombe.
15 tor 1 (Tbf1), a second TRF1/TRF2 ortholog in S. pombe.
16 nstream components of the meiotic pathway in S. pombe.
17 uble mutant generation in the fission yeast, S. pombe.
18 itotic DSB repair and crossover formation in S. pombe.
19 ity of cleaving nicked HJs during meiosis in S. pombe.
20 the hermes transposon from the housefly into S. pombe.
21 epair to ensure accurate nuclear division in S. pombe.
22 -NXT pathway, is required for mRNA export in S. pombe.
23 tial for efficient nuclear protein import in S. pombe.
24 y species and in heterochromatin assembly in S. pombe.
25 Rae1p is an essential mRNA export factor in S. pombe.
26 sulting from loss of Rho1 GTPase function in S. pombe.
27 , for the coordination of DNA replication in S. pombe.
28 E expansion required for "closed" mitosis in S. pombe.
29 REBP activation and low-oxygen adaptation in S. pombe.
30 terest in developing research projects using S. pombe.
31 osaccharomyces japonicus, unlike its role in S. pombe.
32 mitochondrial proteins in S. cerevisiae and S. pombe.
33 related mutant has only a mild phenotype in S. pombe.
34 oles for Smc5/6 are genetically separable in S. pombe.
35 were most homologous to molecules present in S. pombe (52% identical and 67% homologous for PCRan1 an
36 sis also identified 24 SNPs between ours and S. pombe 972h- strain yFS101 that was recently sequenced
37 ations and down-regulated WEE1 (WEE1 homolog-S. pombe), a kinase that blocks cell-cycle progression.
41 , the septation initiation network (SIN), in S. pombe act through an unknown mechanism to keep the ph
45 ASs) in two yeast species, S. cerevisiae and S. pombe Although >80% of the mRNA genes in each species
47 -modifying enzymes (a PtdIns(4)P-5-kinase in S. pombe and a PI-4-kinase in D. melanogaster) that inte
48 Whereas studies of Mre11 complex mutants in S. pombe and A. thaliana indicate that the complex has o
49 ghly active in inhibiting PCNA function both S. pombe and human cells and showed a high affinity for
50 tural differences are also conserved between S. pombe and humans, suggesting that the S. pombe struct
52 esolution map of transcription elongation in S. pombe and identify divergent roles for Spt4 in contro
53 nd process for crossover formation exists in S. pombe and is consistent with our finding that deletio
54 dated three functional repurposing events in S. pombe and mammalian cells and discovered that (1) two
56 duplication in Saccharomyces cerevisiae and S. pombe and PcpA, the anchor for gamma-TuSCs at the SPB
57 ous assays of recombination intermediates in S. pombe and provide new information on the mechanism of
58 er, our data indicate that APA mechanisms in S. pombe and S. cerevisiae are largely different: S. pom
59 n, a section on some key differences between S. pombe and S. cerevisiae is included for readers with
60 ighly purified factors between reconstituted S. pombe and S. cerevisiae transcription systems, we con
61 f the transcription mechanism differ between S. pombe and S. cerevisiae, but are conserved between S.
62 ing the distinct initiation patterns between S. pombe and S. cerevisiae, but rather, these patterns a
65 ucleosome-excluding sequences functioning in S. pombe and S. octosporus, and binding sites for trans-
66 nscriptional interference are shared between S. pombe and the highly divergent budding yeast Saccharo
67 r and Tc5 elements by horizontal transfer in S. pombe (and humans) is accompanied by alteration of th
72 cts affect but do not deplete nucleosomes in S. pombe, and they prefer special rotational positions w
73 species approximately 350 million years ago, S. pombe appears to have evolved less rapidly than S. ce
80 cts the kinase activity and stability of the S. pombe Aurora B homologue, Ark1, colocalizes with know
82 gamma-H2A/X phosphate is likely conserved in S. pombe Brc1 and human Mdc1 genome maintenance proteins
83 iated heavy metal detoxification not only in S. pombe but also in some invertebrates while at the sam
84 ng is highly predictable by A/T frequency in S. pombe but not in S. cerevisiae, suggesting that the g
85 rved biological pathways that are present in S. pombe, but not S. cerevisiae, and will enable a compr
90 us by the FEAR network and Cdk1, whereas the S. pombe CDC14-like phosphatase Clp1p (also known as Flp
96 A damage sites could provide a mechanism for S. pombe cells to arrest at G(2)/M boundary in response
99 osynthesis is selectively blocked in mutated S. pombe cells, their ability to acquire exogenous hemin
103 vious studies have suggested that functional S. pombe centromeres lack regularly positioned nucleosom
107 proteome-wide binary protein interactome for S. pombe, comprising 2,278 high-quality interactions, of
112 nitiator Dpb11 (ortholog of human TopBP1 and S. pombe Cut5), and the multifunctional nuclease/helicas
114 s of tRFs for eight species: R. sphaeroides, S. pombe, D. melanogaster, C. elegans, Xenopus, zebra fi
115 e switch-activating protein Sap1 is a GRF in S. pombe, demonstrating the general applicability of our
116 rticle outlines the way in which interest in S. pombe developed and spread from Europe to Japan, Nort
121 ound with mutations affecting the same gene, S. pombe erf2 (sp-erf2), encoding sp-Erf2, a palmitoyltr
124 An alanine scan of 11 conserved positions of S. pombe Fcp1 identifies Thr(174), Tyr(237), Thr(243), a
125 have observed the growth characteristics of S. pombe for N=100 cells to determine the growth phenoty
126 the Cdc14-family phosphatase, called Clp1 in S. pombe, from being sequestered and inhibited in the nu
127 e than cells lacking zwf1 We propose that in S. pombe Gcd1 and Idn1 act together to shunt glucose int
128 hese studies reveal that convergent genes in S. pombe generate overlapping transcripts in the G1 phas
129 nts, we identified Cdc48-binding proteins in S. pombe, generating a list of many previously unknown p
131 26 heptamer sequence occurs in the wild-type S. pombe genome approximately 300 times, but it has been
136 APA features of higher species, and Pab2 in S. pombe has a different role in APA regulation than its
138 mbe and S. cerevisiae are largely different: S. pombe has many of the APA features of higher species,
139 major motor involved in ring contraction in S. pombe." Here, we show that most of the differences ob
141 MT-1 suppresses the Cd2+ hypersensitivity of S. pombe hmt-1 mutants and localizes to the vacuolar mem
145 alian XPG (also known as ERCC5) and ERCC1 in S. pombe homologues Rad13 and Swi10 and biochemical inte
146 together with previous observations made for S. pombe homologues tea1p and tea3p, they have broad imp
150 thaliana OXS3 to enhance stress tolerance in S. pombe, indicating a role in stress tolerance for the
151 nes are better conserved between the yeasts, S. pombe interactions are significantly better conserved
152 r data argue that trans-histone crosstalk in S. pombe involves direct enhancement of Set1C methyltran
153 orter linker length previously identified in S. pombe is due to a preponderance of nucleosomes separa
162 ponse, we show that modest overexpression of S. pombe los1(+) (also known as Xpo-t), encoding the nuc
163 subtilis lumazine synthase (Ki 2.6 microM), S. pombe lumazine synthase (Ki 0.16 microM), M. tubercul
165 These results suggest that PDE activity in S. pombe may be coordinately regulated with adenylate cy
169 at Mal3 makes a distinctive footprint on the S. pombe microtubule lattice and that unlike mammalian m
170 tice and that unlike mammalian microtubules, S. pombe microtubules do not show the longitudinal latti
171 stituted dynamically unstable single isoform S. pombe microtubules with full length Alp14/TOG and Alp
173 is I and to suppress merotelic attachment in S. pombe mitosis, and crosslinking rDNA repeats to aid r
174 of Rab-GTPase activity is a property of the S. pombe MOP essential for the initiation of membrane fo
176 sufficient for polar cell extension, but in S. pombe, MTs are in addition required for the establish
177 n approach to directly select for long-lived S. pombe mutants from a random DNA insertion library.
182 E1-Sup1 cells depend on the late cytokinetic S. pombe myosin II isoform, Myp2p, a non-essential prote
183 e localization to nuclei and mitochondria in S. pombe, neither of the S. cerevisiae homologs, nor hum
184 rs of low oxygen adaptation, we screened the S. pombe nonessential haploid deletion collection and id
187 revisiae, A/T-rich sequences are enriched in S. pombe nucleosomes, particularly at +/-20 bp around th
191 formation of stable protein-DNA complexes at S. pombe origins of replication involves binary interact
195 ogether, results reported here revealed that S. pombe possesses an unexpected pathway for heme assimi
199 of S. pombe profilin and homology models of S. pombe profilin bound to actin show how the two profil
202 an bind and unwind both DNA and RNA, but the S. pombe protein is not essential and has not been demon
204 cterized fungal proteins, including a second S. pombe protein that is not functionally redundant with
205 ere, we isolate a previously uncharacterized S. pombe protein through association with the Cdc14 phos
206 at one of the AT-STUbLs least related to the S. pombe protein, AT-STUbL4, has acquired a plant-specif
209 minished for Atl1 R69A and R69F mutants, and S. pombe R69A and R69F mutants are more sensitive toward
210 verified utility by C-terminally tagging the S. pombe rad4 and swi1 genes with yEGFP and the yEGFP de
215 dition to the endoribonuclease Dcr1, RNAi in S. pombe requires two interacting protein complexes, the
217 emperature-sensitive and knockout strains of S. pombe, respectively, further verified the functions o
219 ns identified here as subject to skipping in S. pombe reveals high sequence conservation and perfect
220 isome component C20orf43/RTF2 (homologous to S. pombe Rtf2) must be removed for fork restart to be op
225 , Pidoux et al. and Williams et al. identify S. pombe Scm3 as the proximate factor in the Cnp1/CENP-A
226 romeric nucleosomes, the dynamic behavior of S. pombe Scm3 suggests that it acts as a Cnp1 assembly/m
229 Taken together, our results suggest that the S. pombe septins participate redundantly in one or more
233 s in each species were found to display APA, S. pombe showed greater 3' UTR size differences among AP
235 erevisiae SIR2 gene can function in place of S. pombe sir2(+), suggesting overlapping deacetylation s
236 ith single-particle averaging to localize 14 S. pombe SPB components and regulators, determining both
237 e first comprehensive molecular model of the S. pombe SPB, resulting in structural and functional ins
245 ed mmd4 in a screen of temperature-sensitive S. pombe strains for aberrant mitochondrial morphology a
246 SVs in the genomes of a worldwide library of S. pombe strains, including duplications, deletions, inv
247 cript levels in wild-type and zfs1-deficient S. pombe strains; those elevated in the zfs1-deficient s
250 een S. pombe and humans, suggesting that the S. pombe structure may be a good surrogate for that of t
252 s observed in B. subtilis, S. cerevisiae and S. pombe, such as the tendency of FRS to increase from t
255 ntriguingly, unlike their human counterpart, S. pombe SWIRM complex contains neither a histone deacet
257 ken together, these results suggest that the S. pombe system described here can be employed for compa
259 eotide consisting of two conserved hexameric S. pombe telomere repeats, d(GGTTACGGTTAC), with an affi
262 the heterogeneous spacers that occur between S. pombe telomeric repeats, and it also has implications
267 is a TOG-family microtubule polymerase from S. pombe that tracks plus ends and accelerates their gro
268 ify a pause in early elongation, specific to S. pombe, that requires the conserved elongation factor
269 at for two distant yeasts (S. cerevisiae and S. pombe), the only other organisms comprehensively exam
273 hat sla1(+) regulates AAM mRNA production in S. pombe through its effects on nuclear tRNA processing
274 tch from proliferation to differentiation in S. pombe through the dynamic and opposing activities of
276 shu1(+) that encodes a protein that enables S. pombe to take up extracellular heme for cell growth.
280 phy reveals that microtubules assembled from S. pombe tubulin have predominantly B-lattice interproto
283 s could completely substitute for the native S. pombe TZF domain, as determined by measurement of tar
285 of protein SUMOylation, and we identified an S. pombe Ulp2/Smt4 homolog that, when overexpressed, red
286 -specific transcriptome of the fission yeast S. pombe under multiple growth conditions using a novel
289 reas both species divide in the middle, only S. pombe uses the anillin Mid1 as a primary nucleus-deri
290 SINaTRA by predicting synthetic lethality in S. pombe using S. cerevisiae data, then identify over on
291 ters abolishes phytochelatin accumulation in S. pombe vacuoles and abrogates (35)S-PC(2) uptake into
292 are lethal in S. cerevisiae, they are not in S. pombe We show that the lethality of a temperature-sen
293 rgosterol with respect to wild-type Dap1p in S. pombe, we find that Dap1pY138F expression is still su
294 a genome-wide approach in the fission yeast S. pombe, we have found that Dcr1, but not other compone
295 nes suggests Tf1 may improve the survival of S. pombe when cells are exposed to environmental stress.
296 port a novel mechanism for oxygen-sensing in S. pombe, whereby the 2-OG-Fe(II) dioxygenase Ofd protei
298 mouse, rat, mouse-ear cress, fruit fly, the S. pombe yeast, the E. coli bacterium and the M. jannasc
300 in techniques, we replaced the TZF domain of S. pombe Zfs1 with the equivalent domains from human TTP
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