ライフサイエンスコーパス: SECM

1 SECM images showing the presence of Pb (2+) and Cd (2+)

2 SECM imaging allowed the determination of different morp

3 SECM measurements of the patterned cells, performed with

4 SECM screening identified Pd(50)Co(50) (Pd/Co = 50:50, a

5 SECM-based CV is obtained under high mass-transport cond

6 SECM-based nanogap voltammetry in approximately 1 ppb-TO

7 A SECM tip generates a titrant from a reversible redox med

8 spots deposited onto glassy carbon (GC) as a SECM substrate.

9 adical ions in the microgap formed between a SECM probe and a transparent microsubstrate provides a d

10 This generated a SECM image that showed the electrocatalytic activity of

11 rent scanning electrochemical microscopy (AC-SECM) for simultaneous measurements of impedance and far

12 es will be presented along with combined AFM-SECM approach curves and imaging.

13 The thin insulation layer for combined AFM-SECM probes renders this fabrication technique particula

14 Characterization of PFE-insulated AFM-SECM probes will be presented along with combined AFM-SE

15 e - scanning electrochemical microscopy (AFM-SECM) imaging of topography and redox species diffusion

16 opy-scanning electrochemical microscopy (AFM-SECM) probes.

17 Overall, we demonstrate that Mt/AFM-SECM enables high throughput reading of dense nanoarrays

18 We show that the high resolution of Mt/AFM-SECM enables the electrochemical interrogation of severa

19 , operated in molecule touching mode (Mt/AFM-SECM), and of dense nanodot arrays, for designing an ele

20 ographical data under force control (QNM-AFM-SECM).

21 solvents, probes, and mediators) used in all SECM publications since 1989, irrespective of the applic

22 oducing two novel features into amperometric SECM tips based on the micropipet-supported interface be

23 An SECM approach curve of (ferrocenylmethyl)trimethylammoni

24 We used this new type of Ca(2+)-ISME as an SECM probe to quantitatively map the chemical microenvir

25 experiments, and (4) the construction of an SECM stage to avoid artifacts in SECM images.

26 xpansion and contraction of components of an SECM stage upon a temperature change and can be dramatic

27 a peak current response is obtained when an SECM tip is laterally scanned above an insulating nanoga

28 w to moderate scan voltammetry) and analyzes SECM data assuming simple ET kinetics at the substrate a

29 XRD, contact angle, SEM, AFM and SECM studies revealed that the surface of the metal was

30 RP1 were determined using flow cytometry and SECM, and our findings show that these parameters do not

31 implementation of HIC-SECM is described, and SECM feedback measurements in three-dimensional (3D) spa

32 rodes such as, e.g., in vivo experiments and SECM experiments.

33 Optical microscopy and SECM revealed that cells adapt to the underlying surface

34 CV at scan rates to 100 V/s and SECM indicated the reaction pathway involves ligand-coup

35 We used flat, polished nanoelectrodes as SECM tips to carry out feedback mode imaging of various

36 aging was also performed using nanopipets as SECM tips.

37 ive feedback as well as other modes, such as SECM approach curves performed at substrates displaying

38 ASV-SECM can thus be used to detect and study induced dissol

39 ion phenomena may relate to the observed ASV-SECM behavior.

40 In addition, a single ASV-SECM image is shown to produce unique concentration maps

41 tween SECM tip and substrate or collected at SECM substrate (e.g., an Au UME).

42 precise and accurate positioning of Hg-based SECM probes over any sample and enable the deployment of

43 l equations to optimize the coupling between SECM imaging and mass spectrometry detection.

44 e to form oxalate within the nanogap between SECM tip and substrate or collected at SECM substrate (e

45 The recessed geometry is noticeable also by SECM but is not obvious from a cyclic voltammogram.

46 observed both by fluorometric as well as by SECM measurements.

47 m, drug delivery, and toxicity assessment by SECM.

48 ntermediate Sn(III) species was confirmed by SECM(3-), where the Sn(III) generated at the Au tip was

49 of GTC on cancer cells could be confirmed by SECM, and the presented study shows an alternative appro

50 The DMA(*+) intermediate is detected by SECM, where the DMA(*+) generated at the ca. 500 nm radi

51 ver, extracting intracellular information by SECM is challenging, since it requires redox species to

52 he aqueous phosphate buffer/SLG interface by SECM, in both generation/collection (G/C) and feedback m

53 lity of the NPCs is successfully measured by SECM and theoretically analyzed.

54 of living fibroblast cells, was monitored by SECM approach curves and through imaging of the uptake a

55 and the roof permeability can be obtained by SECM using a small probe molecule, ferrocenemethanol (Fc

56 tive tool for visualizing cell properties by SECM.

57 rgest determined for a substrate reaction by SECM.

58 ogen peroxide production was also studied by SECM.

59 g of an open SICM barrel, and a solid carbon SECM electrode enabled correlation of surface activity w

60 In each case, SECM images, obtained at increasing times, show a gradua

61 rication of scanning probe tips that combine SECM with atomic force microscopy (AFM) to perform measu

62 al devices supplementing existing commercial SECM instruments.

63 proof-of-concept is demonstrated by coupling SECM with matrix-assisted laser desorption/ionization ma

64 k is placed in the emission path of our dual SECM/optical microscope, generating a double helix point

65 In addition, a solid-state dual SECM pH probe was used to correlate the release of calci

66 t to avoid electrochemical tip damage during SECM experiments, and (4) the construction of an SECM st

67 nism for measuring the tip-sample gap during SECM experiments, it also enables facile tip alignment a

68 es under the conditions of positive feedback SECM.

69 ly shaped carbon paste UMEs, appropriate for SECM measurements and micrometer to nanometer gap experi

70 In this Article, the theory is developed for SECM current vs distance curves obtained with a disk-sha

71 on microscopy (TEM) of quartz nanopipets for SECM imaging of single solid-state nanopores by using na

72 The suitability of the probes for SECM-SICM imaging is demonstrated by both feedback-mode

73 the disk electrode (RG values) suitable for SECM experiments.

74 dopamine is a well-adapted redox system for SECM in feedback mode and in unbiased conditions.

75 The isothermal chamber is useful for SECM and, potentially, for other scanning probe microsco

76 confirmed and kinetically characterized from SECM toward an insulating substrate, with promising pote

77 fouled electrode surface was determined from SECM approach curves, allowing a comparison of insulatin

78 and experimental high speed constant height SECM imaging.

79 establish a kinetic "map" of constant-height SECM scans, free of topography contributions.

80 HIC-SECM combines a hopping imaging mode, in which data are

81 itous in chemistry and allied areas, and HIC-SECM opens up the possibility of detailed flux visualiza

82 Moreover, because HIC-SECM utilizes an oscillating probe, alternating current

83 act-scanning electrochemical microscopy (HIC-SECM) is introduced as a powerful new technique for the

84 The implementation of HIC-SECM is described, and SECM feedback measurements in thr

85 diffusion layer was studied by hydrodynamic SECM in the substrate generation/tip collection (SG/TC)

86 ionally, preliminary studies of hydrodynamic SECM imaging of a 2 mm Pt disk electrode surface in the

87 in quiescent solution show that hydrodynamic SECM offers attractive complementary information.

88 The hydrodynamic SECM system integrates a high-precision stirring device

89 ction of an SECM stage to avoid artifacts in SECM images.

90 The interest of catechol in SECM as a sensitive redox mediator is exemplified by mon

91 encapsulate ultramicroelectrodes employed in SECM, is also found to be important and affects the volt

92 the approach curve and probe scan methods in SECM.

93 Time-lapse SECM imaging revealed a suitable window of 30 min to com

94 often lose a current response or give a low SECM feedback in current-distance curves.

95 Here, we employed the T-UME to measure SECM approach curves and showed remarkable approach capa

96 m S. epidermidis conditioned culture medium (SECM), but not similar preparations from other bacteria,

97 chemical-scanning ion conductance microcopy (SECM-SICM) has been used to map the electroactivity of s

98 of the scanning electrochemical microscope (SECM) can be used to sensitively probe and alter the mix

99 The scanning electrochemical microscope (SECM) equipped with a nanometer-sized tip was recently u

100 in the scanning electrochemical microscope (SECM) for surface patterning with the spatial resolution

101 on the scanning electrochemical microscope (SECM) operating in a transient feedback mode for the det

102 ip of a scanning electrochemical microscope (SECM) perpendicular to the substrate in a sinusoidal fas

103 used as scanning electrochemical microscope (SECM) probes because of their inherent fast response tim

104 ith the scanning electrochemical microscope (SECM) to carry out spatially resolved electrochemical ex

105 A scanning electrochemical microscope (SECM) was used to arrange two microelectrodes face-to-fa

106 in the scanning electrochemical microscope (SECM), it can be precisely positioned at the sampling lo

107 in the scanning electrochemical microscope (SECM).

108 in the scanning electrochemical microscope (SECM).

109 mode of scanning electrochemical microscopy (SECM) allows for spatially resolved detection of a nanog

110 Scanning electrochemical microscopy (SECM) allows imaging and analysis of a variety of biolog

111 d using scanning electrochemical microscopy (SECM) and fluorescence microscopy.

112 ed from scanning electrochemical microscopy (SECM) and generator-collector experiments, as well as an

113 ng) for scanning electrochemical microscopy (SECM) and have determined their sensitivity to glucose a

114 noscale scanning electrochemical microscopy (SECM) and neurochemical analysis inside single cells.

115 ty with Scanning Electrochemical Microscopy (SECM) and obtain conductivity maps of heterogeneous subs

116 tion of scanning electrochemical microscopy (SECM) and scanning electrochemical cell microscopy (SECC

117 aces by scanning electrochemical microscopy (SECM) and to probe molecules present or generated at the

118 mode of scanning electrochemical microscopy (SECM) and voltammetric methods.

119 CV) and scanning electrochemical microscopy (SECM) approach curves and imaging.

120 ) using scanning electrochemical microscopy (SECM) as an alternative to the widely used rotating ring

121 Scanning electrochemical microscopy (SECM) can map surface characteristics, record catalyst a

122 te that scanning electrochemical microscopy (SECM) can quantitatively and noninvasively track multidr

123 se as a scanning electrochemical microscopy (SECM) chemical probe to quantitatively map the microbial

124 de on a scanning electrochemical microscopy (SECM) configuration and was used to record approach curv

125 ed in a scanning electrochemical microscopy (SECM) configuration, and their use for both approach cur

126 typical scanning electrochemical microscopy (SECM) configuration.

127 mode of scanning electrochemical microscopy (SECM) coupled with linear voltammetry is proposed as a w

128 hod for scanning electrochemical microscopy (SECM) employing fast-scan anodic stripping voltammetry (

129 odes by scanning electrochemical microscopy (SECM) enables voltammetric measurement of ultrafast elec

130 SV) and scanning electrochemical microscopy (SECM) experiments.

131 ed with scanning electrochemical microscopy (SECM) for in situ spectroscopic detection of electrochem

132 gulated scanning electrochemical microscopy (SECM) has been associated with Raman microspectrometry i

133 ecades, scanning electrochemical microscopy (SECM) has been extensively employed for topographic imag

134 Scanning electrochemical microscopy (SECM) has been widely used for the electrochemical imagi

135 des and scanning electrochemical microscopy (SECM) have recently been used to measure kinetics of sev

136 ted for scanning electrochemical microscopy (SECM) imaging of molecular microarrays.

137 use of scanning electrochemical microscopy (SECM) in determining the heterogeneous electron transfer

138 obe for scanning electrochemical microscopy (SECM) in order to map pH over a platinum ultramicroelect

139 ed with scanning electrochemical microscopy (SECM) in order to provide both spectroscopic and electro

140 FM with scanning electrochemical microscopy (SECM) in PFT mode, thereby offering spatially correlated

141 llowing scanning electrochemical microscopy (SECM) in positive feedback mode at a close distance, whi

142 ted for scanning electrochemical microscopy (SECM) in the tip generation-substrate collection (TG-SC)

143 ME) for scanning electrochemical microscopy (SECM) investigations of any substrate.

144 tor for scanning electrochemical microscopy (SECM) investigations was evaluated in the challenging si

145 noscale scanning electrochemical microscopy (SECM) is a powerful scanning probe technique that enable

146 Scanning electrochemical microscopy (SECM) is a powerful tool that enables quantitative measu

147 Scanning electrochemical microscopy (SECM) is a rising technique for the study of energy stor

148 ips for scanning electrochemical microscopy (SECM) is a slow and cumbersome task that often results i

149 Scanning electrochemical microscopy (SECM) is an electroanalytical scanning probe technique c

150 mode of scanning electrochemical microscopy (SECM) is demonstrated.

151 form of scanning electrochemical microscopy (SECM) is described.

152 mode of scanning electrochemical microscopy (SECM) is extended to the in situ quantification of adsor

153 Scanning electrochemical microscopy (SECM) is increasingly applied to study and image live ce

154 CM) and scanning electrochemical microscopy (SECM) measurements is demonstrated to have powerful new

155 died by scanning electrochemical microscopy (SECM) on single-layer graphene (SLG).

156 y using scanning electrochemical microscopy (SECM) permits measurement of heterogeneous standard elec

157 IS) and scanning electrochemical microscopy (SECM) techniques were employed in the characterization o

158 thod of scanning electrochemical microscopy (SECM) that can be used to separate multireactional elect

159 A new scanning electrochemical microscopy (SECM) tip positioning method that allows surface topogra

160 e) as a scanning electrochemical microscopy (SECM) tip to detect silver ion and explore Ag+ toxicity

161 Scanning electrochemical microscopy (SECM) tips with rounded glass insulation around the meta

162 e apply scanning electrochemical microscopy (SECM) to demonstrate quantitatively that the electroacti

163 try and scanning electrochemical microscopy (SECM) to determine the radius and the effective depth of

164 ent for scanning electrochemical microscopy (SECM) to enable quasi-steady-state voltammetry of rapid

165 tion of scanning electrochemical microscopy (SECM) to enable the in situ, real-time, and quantitative

166 tip in scanning electrochemical microscopy (SECM) to obtain a two-dimensional image of the local NO

167 ing and scanning electrochemical microscopy (SECM) to probe quorum sensing (QS)-mediated communicatio

168 e apply scanning electrochemical microscopy (SECM) to quantitatively study the permeability of the NP

169 tion of scanning electrochemical microscopy (SECM) to the measurement of the ion-selective permeabili

170 d using scanning electrochemical microscopy (SECM) toward different insulating surfaces such as glass

171 Scanning electrochemical microscopy (SECM) using Hg/Pt UMEs showed that the steady-state amal

172 noscale scanning electrochemical microscopy (SECM) using three-dimensional super-resolution fluoresce

173 Scanning electrochemical microscopy (SECM) was employed as a sensitive tool to investigate th

174 robe in scanning electrochemical microscopy (SECM) was evaluated for the determination of the absolut

175 Scanning electrochemical microscopy (SECM) was used for the study of electrogenerated chemilu

176 try and scanning electrochemical microscopy (SECM) were developed to independently evaluate the elect

177 CV) and scanning electrochemical microscopy (SECM) were used to investigate the reduction of Sn(IV) a

178 perform scanning electrochemical microscopy (SECM) with nanometer-scale resolution.

179 tion of scanning electrochemical microscopy (SECM) with single-bounce attenuated total reflection Fou

180 tate by scanning electrochemical microscopy (SECM) with ultramicroelectrodes using the tip generation

181 In scanning electrochemical microscopy (SECM), an approach curve performed in feedback mode invo

182 , e.g., scanning electrochemical microscopy (SECM), cannot be used as a robust alternative yet becaus

183 mode of scanning electrochemical microscopy (SECM), extending the number of applications of SECM in e

184 s using scanning electrochemical microscopy (SECM).

185 ry, and scanning electrochemical microscopy (SECM).

186 mode of scanning electrochemical microscopy (SECM).

187 ing and scanning electrochemical microscopy (SECM).

188 se with scanning electrochemical microscopy (SECM).

189 time by scanning electrochemical microscopy (SECM).

190 back in scanning electrochemical microscopy (SECM).

191 d using scanning electrochemical microscopy (SECM).

192 such as scanning electrochemical microscopy (SECM).

193 time by scanning electrochemical microscopy (SECM).

194 ores by scanning electrochemical microscopy (SECM).

195 ions of scanning electrochemical microscopy (SECM).

196 ing and scanning electrochemical microscopy (SECM).

197 tips in scanning electrochemical microscopy (SECM).

198 time by scanning electrochemical microscopy (SECM).

199 ICM and scanning electrochemical microscopy (SECM).

200 died by scanning electrochemical microscopy (SECM).

201 on with scanning electrochemical microscopy (SECM).

202 FM) and scanning electrochemical microscopy (SECM).

203 ally by scanning electrochemical microscopy (SECM).

204 chemical microscopy-atomic force microscopy (SECM-AFM) have been batch-fabricated, and their applicat

205 rming a scanning electrochemical microscopy-(SECM) like approach of a Pt microelectrode (ME), which w

206 during Ru(bpy)(3)(2+) mediated feedback mode SECM experiments.

207 are suitable for quantitative feedback mode SECM experiments.

208 olymer depositions induced via feedback mode SECM using a 25 mum Pt disk ultramicroelectrode (UME).

209 mparable to those obtained in recent nanogap/SECM experiments.

210 enabled us to successfully build a nanoscale SECM, which can be utilized to map the electrocatalytic

211 turized more readily to facilitate nanoscale SECM imaging.

212 e and hardware instrumentation for nanoscale SECM are explicitly explained including (1) the LabVIEW

213 task to quantitatively understand nanoscale SECM images, which requires accurate characterization of

214 ) to allow images to be acquired in a normal SECM time frame.

215 ct was relevant in vivo as administration of SECM to mice decreased susceptibility to infection by GA

216 Herein, we demonstrate the advantage of SECM-based nanogap voltammetry to assess the cleanness o

217 CM), extending the number of applications of SECM in electrocatalysis.

218 The powerful combination of SECM with cyclic voltammetry (CV) at a gold substrate re

219 ntracellular content through the coupling of SECM with immunoassay strategies for the detection of sp

220 Hg-based probes allow the extension of SECM investigations to ionic processes, but the risk of

221 e electrochemically investigated by means of SECM.

222 ve was recorded in negative feedback mode of SECM and revealed the contact point of the ME and WE on

223 d pH was carried out using the SG/TC mode of SECM to demonstrate the utility of this technique in det

224 ith the tip currents in the feedback mode of SECM.

225 the substrate in the proposed MD-SC mode of SECM.

226 CM tip to the substrate in the TG-SC mode of SECM.

227 This finding demonstrates the usefulness of SECM in quantitative studies of MRP1 inhibitors and sugg

228 0 peer-reviewed publications have focused on SECM, including several topical reviews.

229 ons demonstrate the unique capability of our SECM chemical probes for studying real-time metabolic in

230 y sample and enable the deployment of CV-PAS SECM as an analytical tool for traditionally challenging

231 al focus with a single, precisely positioned SECM nanostructure.

232 y confirming the reliability of quantitative SECM imaging at the nanoscale level.

233 The quantitative SECM image of single nanopores allows for the determinat

234 High-resolution SECM images of ferrocenemethanol (FcMeOH) oxidation, ben

235 rk demonstrates the value of high-resolution SECM-SICM for low-current amperometric imaging of nanosy

236 o proof-of-concept applications in the TG-SC SECM modality are described.

237 One-directional lateral scan SECM was used as a rapid and reproducible tool for simul

238 One-directional y-scan SECM measurements showed the unique spatial mapping of h

239 e ions is enabled by using the ion-selective SECM tips based on the micropipet- or nanopipet-supporte

240 vel photoelectrocatalytic materials, several SECM-based techniques have been developed, aiming on the

241 By SI-SECM, independent titrations of surface Co(III) and Co(I

242 hemical microscopy surface interrogation (SI-SECM) in the cyclic voltammetry mode was successfully us

243 tion scanning electrochemical microscopy (SI-SECM), fine and accurate control of the delay time betwe

244 tion scanning electrochemical microscopy (SI-SECM).

245 The use of SI-SECM allowed access to a reaction that would otherwise b

246 The rapid switching SI-SECM has been implemented in a substrate generation-tip

247 has been measured by the rapid switching SI-SECM.

248 ay control up to ca. 1 mus, enhancing the SI-SECM to be competitive in the time domain with the decay

249 In previous applications of the SI-SECM, the resolution in the control of tdelay has been l

250 Significantly, SECM-based CV will be useful for the in situ characteriz

251 quipment was found to be adequate for simple SECM measurements under hindered diffusion conditions.

252 Comparison of experimental and simulated SECM approach curves, images, and tip voltammograms enab

253 remarkable approach capability for a nm-size SECM probe.

254 based on forced convection during high speed SECM imaging.

255 A steady-state SECM diffusion problem with a pair of disk ultramicroele

256 This probe geometry enables successful SECM-SICM imaging on features as small as 180 nm in size

257 The SECM approach curves depend on the substrate bias and st

258 The SECM configuration makes it possible to observe in the s

259 The SECM methodology also demonstrates how dissolved oxygen

260 The SECM tip, which generated a constant formic acid flux, w

261 For quantitative analysis, the SECM approach curves using dopamine could simply be char

262 itive feedback between the substrate and the SECM microelectrode tip.

263 a Hg/Au film UME, which were utilized as the SECM tips.

264 positive feedback signal was observed at the SECM electrode, and the topographical channel compared w

265 The extracellular ROS level detected at the SECM tip was found to be similar to the intracellular RO

266 dation of a Fe(II) species, generated at the SECM tip, under conditions in which SLG shows slow inter

267 r environment, thiodione was detected by the SECM tip at levels of 140, 70, and 35 microM upon exposu

268 = d/a and d is the distance traveled by the SECM tip, was observed in both systems (e.g., I(T)(L) =

269 Therefore, this strategy can be used for the SECM investigation of cell topography or the passive tra

270 From the SECM study Hg shows n close to 2, whereas Pt and Pd80Co2

271 eflection is qualitatively detected from the SECM tip current measurement and a quantitative estimate

272 NI) was deposited electrochemically from the SECM tip side until it bridged the two electrodes.

273 his aim, adherent cells were analyzed in the SECM feedback mode in three different conditions: (i) al

274 The well-defined stirring of the SECM electrolyte results in steady state diffusion layer

275 A finite element simulation of the SECM image was performed to assess quantitatively the sp

276 ent particle to the insulating sheath of the SECM tip extends this technique to nonfluorogenic electr

277 The scanning tip of the SECM was replaced by a fiber optic connected to a xenon

278 k generation-collection configuration of the SECM.

279 cts of reversible reactant adsorption on the SECM response.

280 structured Pd hydride films deposited on the SECM tip.

281 Overall, the SECM results correlate well with the fluorescence result

282 g (1) the LabVIEW code that synchronizes the SECM tip movement with the electrochemical response, (2)

283 current responses and also reveals that the SECM images of 100 nm diameter Si3N4 nanopores are enlar

284 rt the amounts of this adsorbate through the SECM feedback response.

285 ioning control without risking damage to the SECM probe, we implement cyclic voltammetry probe approa

286 e positioning of target cells underneath the SECM sensor.

287 ifferent cancer progression stages using the SECM substrate generation-tip collection mode.

288 th spatial and temporal resolution using the SECM tip.

289 system by carrying out experiments with the SECM and light-detecting apparatus inside an inert atmos

290 from the local perturbation induced with the SECM tip to the substrate in the TG-SC mode of SECM.

291 roduction above single cancer cells with the SECM.

292 divided by the electrode radius), and their SECM feedback approach curves were studied in solutions

293 Thus, SECM kinetic measurements, particularly in a nanogap con

294 probes for bulk measurements extends also to SECM studies, where the disc geometry facilitates small

295 In other words, it is a practical guide to SECM.

296 The extension of the model to SECM-induced transfer is considered and it is shown that

297 eatment, as evidenced by the analysis of TPM-SECM approach curves (current-distance characteristics).

298 chamber to be detected and quantified using SECM.

299 - and microelectrodes to soft surfaces using SECM for a rapid and more convenient characterization an

300 uantification of the conductivity of GO with SECM.