ライフサイエンスコーパス: SFT

1 SFT (stimulator of Fe transport) is a novel transport pr

2 SFT and SP influenced cotton domestication and are ideal

3 SFT expression did not enhance levels of HeLa cell surfa

4 SFT expression was not affected by iron.

5 SFT has six predicted transmembranous domains and a func

6 SFT is the first component of the mammalian Fe membrane

7 SFT promises to advance the goal of full automation in i

8 SFT would be acceptable for use in larger studies.

9 SFT-mediated transport has properties defined for transf

10 The 1-SST, 1-FFT and 6-SFT genes had correlated expression patterns in our whea

11 nd sucrose:fructan 6-fructosyltransferase (6-SFT) were clustered together with multiple copies of vac

12 ncluding LA, flower with fewer leaves via an SFT-dependent pathway, suggesting that miR319-sensitive

13 isplacement plethysmography body density and SFT methods showed positive (overestimating) constant bi

14 splacement plethysmography body density, and SFT ranging from a mean +/- SD of 29.5 +/- 13.2 kg via 4

15 The gene expression of DMT1, HFE, and SFT did not fully correlate with the functional response

16 lated with gene expression of DMT1, HFE, and SFT in an experimental model of human absorptive enteroc

17 amined and gene expression of DMT1, HFE, and SFT was measured.

18 demonstrate that iron transport mediated by SFT is itself an iron-dependent process.

19 Transport mediated by SFT was inhibitable by diethylenetriaminepentaacetic aci

20 nvolved in cellular iron assimilation called SFT or Stimulator of Fe Transport.

21 When stably expressed in HeLa cells, SFT was found to stimulate the uptake of both transferri

22 is patients therefore suggests that enhanced SFT expression contributes to the etiology of this iron

23 th control cells and cells stably expressing SFT displayed reduced Fe uptake as well; levels of trans

24 rin-bound Fe by HeLa cells stably expressing SFT was time- and temperature-dependent; both the rate a

25 at a ferrireductase activity is required for SFT function in Fe3+ transport and that Cu depletion red

26 Higher SFT performance resulted in greater recruitment of right

27 f these agents in angiosarcoma, EHE, and HPC/SFT are poorly understood.

28 ally low, several angiosarcoma, EHE, and HPC/SFT patients demonstrated response or durable disease st

29 ain patients with angiosarcoma, EHE, and HPC/SFT, but more studies are needed to confirm these findin

30 d as a potentially promising regimen for HPC/SFT.

31 rials will not only improve treatment of HPC/SFT but will also lead to a new paradigm of personalized

32 olecular pathogenesis and aberrations of HPC/SFT is needed to determine optimal therapeutic agents.

33 to the relatively insensitive nature of HPC/SFT to radiotherapy and cytotoxic chemotherapy, new ther

34 al features, diagnosis, and treatment of HPC/SFT.

35 mangiopericytoma/solitary fibrous tumor (HPC/SFT) spectrum of tumors, focusing on the histopathologic

36 mangiopericytoma/solitary fibrous tumor (HPC/SFT).

37 sis of multicolor, tissue-microarray images, SFT correctly found the overlap of markers with known su

38 ntracellular iron by desferrioxamine impairs SFT transport and iron-binding functions.

39 NAB2-STAT6 fusion proteins was confirmed in SFT, and the predicted fusion products harbor the early

40 ted cells suggests a critical role for Cu in SFT function.

41 e-binding studies reveal that the ability of SFT to bind and mediate transport of extracellular iron

42 To test this hypothesis, the ability of SFT to directly mediate Fe2+ import was examined.

43 or Fe uptake was unaffected by expression of SFT (5.6 versus 5.1 microM measured for control), the Vm

44 Although expression of SFT enhanced Fe2+ uptake by HeLa cells, Cu depletion did

45 The failure of SFT expression to stimulate Fe uptake above basal levels

46 r characterize the structure and function of SFT, we studied this human factor in rodent BHK cells.

47 slation inhibitory element and inhibition of SFT expression in Xenopus oocytes was found to be reliev

48 the iron chelator desferrioxamine, levels of SFT mRNA increase in an actinomycin D-sensitive manner.

49 AB2-STAT6 as the defining driver mutation of SFT and provide an example of how neoplasia can be initi

50 The 3' untranslated region of SFT contains a translation inhibitory element and inhibi

51 Thus, homeostatic regulation of SFT expression not only ensures that sufficient levels o

52 ated the effects of Cu (copper) depletion on SFT function.

53 account for the influence of Cu depletion on SFT-mediated Fe uptake.

54 ort the concept that classic pleuropulmonary SFT and deep-seated HPC are separate entities that share

55 exposed to high levels of iron down-regulate SFT expression in a time-dependent and reversible fashio

56 tif may play an important role in regulating SFT activity through interaction with intracellular iron

57 Based on the relationships, SFT identifies segments belonging to background regions;

58 with the corresponding aligned PAR1 residues SFT 220-222.

59 loop 5 antibodies recognize and bind surface SFT.

60 Naming Test (BNT) and Semantic Fluency Test (SFT), neuropsychological measures of semantic retrieval,

61 ion Test (COWAT), and Semantic Fluency Test (SFT).

62 Both vacancy-type stacking fault tetrahedra (SFT) and interstitial loops coexist in the same region,

63 Previous studies demonstrated that SFT (Stimulator of Fe Transport) facilitates both transf

64 y and immunofluorescence data and found that SFT performed well over multiple, diverse image characte

65 The observation that SFT oligomerizes, along with other structural and mechan

66 The unexpected observation that SFT transcript levels are up-regulated in hemochromatosi

67 Kyte-Doolittle analysis suggests that SFT has six transmembrane-spanning segments.

68 roblast, and smooth muscle cell types of the SFT.

69 t area (AFA) and subcutaneous fat thickness (SFT) were measured using T1-weighted axial slices at the

70 nt fat mass estimated by skinfold thickness (SFT) measurements at 4 body sites at 3-5 d, 6 wk, and 4

71 e data, called Segment and Fit Thresholding (SFT).

72 A stimulator of Fe transport (SFT) was identified by functional expression cloning in

73 MT1), HFE, and stimulator of iron transport (SFT) are transmembrane proteins that have been implicate

74 le of the florigen gene SINGLE FLOWER TRUSS (SFT) and two mutations affecting a bZIP transcription fa

75 w the FLOWERING LOCUS T/SINGLE FLOWER TRUSS (SFT)-like and TERMINAL FLOWER1/SELF-PRUNING (SP)-like ge

76 h a highly malignant solitary fibrous tumor (SFT) enrolled in our clinical sequencing program called

77 woman with recurrent solitary fibrous tumor (SFT)/hemangiopericytoma was enrolled in a clinical seque

78 nitiating events in solitary fibrous tumors (SFT).

79 kg via 4-compartment to 39.1 +/- 11.7 kg via SFT.

80 her protein terminus does not interfere with SFT function in nontransferrin-bound iron uptake.