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4 odeoxyuridine incorporation studies of adult SGZ in four independent mouse lines showed that Tctex-1:
6 to its exclusive restriction to the SVZ and SGZ or, for instance, to the inadequacy of the methods u
7 neural stem cells (NSC) in both the SVZ and SGZ that are capable of self-renewal and long-term neuro
11 SVZ, but not in contralateral SVZ or either SGZ, in both young adult (3-month-old) and aged (24-mont
13 ll survival in the granular cell layer (GCL)/SGZ was observed in young animals and a slight augmentat
15 However, the total number of hippocampal SGZ-derived new neurons was reduced bilaterally; in cont
16 , in a dose-dependent manner, BrdU+ cells in SGZ in 3xTgAD mice and restored SGZ proliferation to nor
20 path stimulation resulted in an increase in SGZ mitotic activity similar to that seen with pilocarpi
22 CD44-expressing NSCs isolated from the mouse SGZ are self-renewing and capable of differentiating int
23 ny in nestin-CreER(T2)/R26R-YFP mice: 97% of SGZ stem-like cells (GFAP/Sox2 with radial glial morphol
24 of neurogenesis (via FACS and microarray of SGZ stem and progenitor cells) suggested the involvement
25 pment identified a highly overlapping set of SGZ-enriched genes, which can be divided based on tempor
26 self-administration enhanced the survival of SGZ BrdU cells, and methamphetamine seeking during protr
27 and T-maze and had a fewer number of 2-h-old SGZ BrdU cells than nondrug and I-ShA rats, suggesting t
30 -immunopositive (+) neurons in the posterior SGZ and a normal number of adult-generated BrdU+ neurons
32 rty-eight h after irradiation, proliferating SGZ cells were reduced by 93-96%; immature neurons were
35 cal and electron microscopy demonstrate that SGZ astrocytes form baskets that hold clusters of D cell
38 eptor 4-dependent depletion of IPCs from the SGZ and suggest further pharmacological strategies to pr
41 ggest that p21 restrains neurogenesis in the SGZ and imipramine-induced stimulation of neurogenesis m
42 ntly expressed in the nuclei of cells in the SGZ and is colocalized with NeuN, a marker for neurons.
44 lecular control of adult neurogenesis in the SGZ and SVZ, focusing on the role of specific transcript
45 ations of label-retaining cells exist in the SGZ and that Noggin overexpression increases their numbe
46 on and maturation of progenitor cells in the SGZ by enhancing GABA release, at least in part, from PV
49 igestion in wild type NSC cultures or in the SGZ induces increased NSC proliferation, and CD44-null a
50 differentiation, and HA accumulation in the SGZ may contribute to reductions in neurogenesis that ar
51 3 months, basal level of BrdU+ cells in the SGZ of 3xTgAD mice was significantly lower relative to n
52 ssed by a significant number of cells in the SGZ of adult mice in vivo and ex vivo, including postmit
56 tes to NSC maintenance in SVZ but not in the SGZ, and that this is regulated by the biallelic express
57 mber of adult-generated BrdU+ neurons in the SGZ, suggesting an enduring impact of CSA regardless of
67 port that astrocytes in areas outside of the SGZ and SVZ of adult mice express high levels of ephrin-
71 We propose that localized hypoxia within the SGZ contributes to the neurogenic microenvironment and d
72 n of IPCs away from hypoxic zones within the SGZ might result in oxidative damage, thus triggering ce
73 Notch1 iKO mice had similar numbers of total SGZ YFP+ cells 13 and 30 d post-TAM but had significantl
74 pic oGCL cells were still rare compared with SGZ proliferating cells, emphasizing that the primary ch
75 the dentate subgranular proliferative zone (SGZ), an area known to contain neuronal precursor cells.
76 positive stem cells in the subgranular zone (SGZ) and granular cell layer of the dentate gyrus compar
77 nitor cells located in the subgranular zone (SGZ) as well as their derivatives including doublecortin
79 genesis in the hippocampal subgranular zone (SGZ) is involved in learning and memory throughout life
81 erentiation of hippocampal subgranular zone (SGZ) neuroblasts, and the dendritic arborization of adul
84 endogenous Tctex-1 at the subgranular zone (SGZ) of dentate gyrus, ventricular/subventricular zone o
86 two discrete regions, the subgranular zone (SGZ) of the dentate gyrus and the subventricular zone (S
87 continue to be born in the subgranular zone (SGZ) of the dentate gyrus in the hippocampus of adult ma
90 ricular zone (SVZ) and the subgranular zone (SGZ) of the dentate gyrus, express high levels of FGFR-2
93 adult neurogenesis in the subgranular zone (SGZ) of the dentate gyrus; however, the mechanism underl
94 ricular zone (SVZ) and the subgranular zone (SGZ) of the hippocampal dentate gyrus (DG), where VEGFR2
95 l precursor cells from the subgranular zone (SGZ) of the hippocampal dentate gyrus and alterations in
96 re neuronal markers in the subgranular zone (SGZ) of the hippocampal dentate gyrus and the forebrain
97 eurogenic potential of the subgranular zone (SGZ) of the hippocampal dentate gyrus is likely to be re
98 two restricted areas, the subgranular zone (SGZ) of the hippocampus and the subventricular zone (SVZ
101 enesis were evident in the subgranular zone (SGZ) of wild-type (WT) mice (nestin-CreER(T2)/R26R-YFP/N
105 nesis in the dentate gyrus subgranular zone (SGZ), but it is unknown if stress-induced changes in neu
107 genesis in the hippocampal subgranular zone (SGZ), to reverse learning and memory deficits in 3-month
108 adult neurogenesis in the subgranular zone (SGZ), was regulated by cocaine self-administration (CSA)
109 cular zone (V-SVZ) and the subgranular zone (SGZ), with signaling pathways that control the behavior
118 uration in the hippocampal subgranular zone (SGZ); these cells can be identified by the expression of
119 and granule cell layer, or subgranule zone (SGZ), is an area of active proliferation within the adul
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