ライフサイエンスコーパス: SNARE protein

1 erivative that cleaves SNAP23, a nonneuronal SNARE protein.

2 is a unique intracellular location for this SNARE protein.

3 5 (STX5), a member of the syntaxin family of SNARE proteins.

4 me degradation by disrupting the function of SNARE proteins.

5 ed at the end of the transmembrane domain of SNARE proteins.

6 ction between alpha-synuclein and any of the SNARE proteins.

7 ugh interactions with the syntaxin family of SNARE proteins.

8 rocessive unwinding mechanism to disassemble SNARE proteins.

9 ins in membrane fusion by directly acting on SNARE proteins.

10 r evolutionarily conserved structures in the SNARE proteins.

11 ric Golgi (COG) complex and with intra-Golgi SNARE proteins.

12 to neurons and specific cleavage of neuronal SNARE proteins.

13 c binding to nerve terminals and cleavage of SNARE proteins.

14 uires homotypic membrane fusion catalyzed by SNARE proteins.

15 Ca(2+) and through direct interactions with SNARE proteins.

16 rms and requires membrane integration of the SNARE proteins.

17 (SNARE) complexes between vesicle and Golgi SNARE proteins.

18 transmission by endoproteolytic cleavage of SNARE proteins.

19 nd R-SNARE and plasma membrane Qa, Qb and Qc SNARE proteins.

20 calcium channel function by interaction with SNARE proteins.

21 c1/Munc18 (SM) proteins to specific syntaxin SNARE proteins.

22 rm motility, calcium channel regulation, and SNARE proteins.

23 nimal model for membrane fusion, inspired by SNARE proteins.

24 LegC7/YlfA] functionally mimic glutamine (Q)-SNARE proteins.

25 ensitive-factor attachment protein receptor (SNARE) proteins.

26 ensitive factor attachment protein receptor (SNARE) proteins.

27 fusion protein-attachment protein receptors (SNARE) proteins.

28 ensitive factor attachment protein receptor (SNARE) proteins.

29 YP73, a member of the plant Syp7 subgroup of SNARE proteins [9] containing actin-binding domains, is

30 rough the regulation of NMDAR exocytosis via SNARE proteins, a family of proteins involved in vesicle

31 ys can be used to study the roles of various SNARE proteins, accessory proteins and effects of differ

32 ucleins (maintain functional conformation of SNARE proteins after complex disassembly).

33 lexin clamps otherwise spontaneous fusion by SNARE proteins, allowing neurotransmitters and other med

34 coupled to associations between F-actin and SNARE proteins, although the nature and function of thes

35 Fusion involves complex formation between SNARE proteins anchored to adjacent membranes.

36 f the BoNTs, termed A-G, which differ in the SNARE protein and/or site that is cleaved.

37 ficking through interactions with individual SNARE proteins and assembled SNARE complexes.

38 egregate cargo from source compartments, and SNARE proteins and associated factors that cause vesicle

39 sis particularly involving small G proteins, SNARE proteins and chaperone molecules.

40 an ENTH domain-containing protein that binds SNARE proteins and functions in vesicle trafficking; how

41 he plasma membrane (PM) in relation to other SNARE proteins and inhibition of exocytosis.

42 dylinositol 4,5-bisphosphate (PI(4,5)P2) and SNARE proteins and is proposed to promote SNARE protein

43 he internal distribution of fusion-competent SNARE proteins and limiting homotypic fusions among cont

44 n which direct interactions between specific SNARE proteins and PIP aquaporins modulate their post-Go

45 T to the surface by a mechanism dependent on SNARE proteins and protein kinase C-beta but independent

46 s containing elevated levels of the ER-Golgi SNARE proteins and Sly1p were less sensitive to PI(4)P i

47 Although SNARE proteins and tethering complexes mediate intracell

48 Individual SNARE proteins and the SNARE complex itself have been im

49 ific for UNC-64 Syntaxin-1, because 14 other SNARE proteins and two active zone markers were unaffect

50 ensitive factor attachment protein receptor (SNARE) proteins and cytoskeletal proteins.

51 ensitive factor attachment protein receptor (SNARE) proteins and lipid bilayer properties.

52 g of otoferlin C2 domains to target SNARE (t-SNARE) proteins and phospholipids.

53 icking requires membrane fusion, mediated by SNARE proteins, and upstream events that probably includ

54 ent state in which the N-terminal domains of SNARE proteins are assembled.

55 ing scorpion envenomation as both of these v-SNARE proteins are associated with zymogen granule membr

56 Although many SNARE proteins are available per vesicle, only one to th

57 only observe optimal lipid mixing when the t-SNARE proteins are coexpressed before purification.

58 In eukaryotic cells, multiple isoforms of SNARE proteins are expressed and are involved in distinc

59 SNARE proteins are the core elements but the proteins th

60 SNARE proteins are the core machinery to drive fusion of

61 SNARE proteins are the core of the cell's fusion machine

62 ensitive factor attachment protein receptor (SNARE) proteins are key players in cellular trafficking

63 ensitive factor activating protein receptor (SNARE) proteins are the main catalysts for membrane fusi

64 core membrane fusion machinery proteins, the SNARE proteins, are assisted by a group of regulatory fa

65 Here using plasma membrane-resident SNARE proteins as model, we show that hydrophobic mismat

66 Vesicular (v)- and target (t)-SNARE proteins assemble in SNARE complex to mediate memb

67 Vesicle fusion is mediated by an assembly of SNARE proteins between opposing membranes, but it is unk

68 SNARE protein binding by CAPS is novel and mediated by i

69 ctome in mouse brain, we identified not only SNARE proteins but also Munc-18-1 (stabilizes assembled

70 Complexins are unable to bind to monomeric SNARE proteins but bind with high affinity to ternary SN

71 Exocytosis depends on cytosolic domains of SNARE proteins but the function of the transmembrane dom

72 tosomal-associated protein of 25 kDa), a key SNARE protein, by immunocytochemistry with cell type-spe

73 Our study supports the idea that endosomal SNARE proteins can have functions unrelated to membrane

74 SNARE proteins catalyze many forms of biological membran

75 ensitive factor attachment protein receptor (SNARE) proteins catalyze membrane fusion events in the s

76 siologically, alpha-synuclein functions as a SNARE-protein chaperone that promotes SNARE-complex asse

77 y governed through light chain (LC) protease SNARE protein cleavage leading to a loss of neurotransmi

78 nd SNARE proteins and is proposed to promote SNARE protein complex assembly for vesicle docking and p

79 membrane is thought to involve the so-called SNARE protein complex.

80 ules be docked to the plasma membrane by the SNARE protein complex.

81 SNARE protein complexes are key mediators of exocytosis

82 e cells requires a priming step during which SNARE protein complexes assemble.

83 In regulated vesicle exocytosis, SNARE protein complexes drive membrane fusion to connect

84 irect interaction of LegC3 with the vacuolar SNARE protein complexes required for fusion.

85 icking by mediating disassembly and reuse of SNARE protein complexes, which facilitate fusion of vesi

86 ensitive factor attachment protein receptor (SNARE) protein complexes play essential roles in catalyz

87 n, probably via formation of distinct Munc18/SNARE-protein complexes.

88 ve factor (NSF) attachment protein receptor (SNARE) proteins comprise the minimal machinery that trig

89 ensitive factor attachment protein receptor (SNARE) proteins constitute the minimal machinery that ca

90 SNARE proteins-core machinery for membrane fusion-are in

91 new insight into the spatial organization of SNARE protein cycling during synaptic activity.

92 SNARE proteins direct membrane fusion events required fo

93 ensitive factor attachment protein receptor (SNARE) proteins drive membrane fusion by assembling into

94 eimide-sensitive factor attachment receptor (SNARE) proteins drive the fusion of synaptic vesicles to

95 which determines its interaction with other SNARE proteins during fusion, is largely unknown.

96 ensitive factor attachment protein receptor (SNARE) proteins during vesicle formation, and SNARE-medi

97 tion of a highly stable four-helix bundle of SNARE proteins embedded in the vesicle and target membra

98 eins with similar domains of plasma membrane SNARE proteins enhancing fusion of the two membranes to

99 ing microscopy between fluorescently labeled SNARE proteins expressed in cultured rat hippocampal neu

100 fusion involves the action of members of the SNARE protein family as well as Sec1/Munc18 (SM) protein

101 ntaxin-11 (Stx11), an atypical member of the SNARE protein family, is part of the cytolytic machinery

102 Syntaxin-1 is the central SNARE protein for neuronal exocytosis.

103 SNARE proteins form a complex that leads to membrane fus

104 Before fusion, SNARE proteins form complexes bridging the membrane foll

105 The SNARE proteins found in vesicle membranes have previousl

106 yntaxin17, thereby preventing these two host SNARE proteins from mediating autophagosome-lysome fusio

107 by Soluble NSF Attachment Protein Receptor (SNARE) proteins from granule and plasma membranes.

108 a novel, broadly applied mechanism governing SNARE protein function.

109 Our data suggest that SNARE proteins function during fusion primarily as force

110 y Lobe A of the COG complex and the purified SNARE proteins Gos1, Sed5 and Sft1.

111 Here, we characterize the Golgi SNARE protein, Gos28, and its role in rhodopsin (Rh1) tr

112 xin-8 mutant that cannot assemble with other SNARE proteins had virtually the same effect as wild-typ

113 Although multiple SNARE proteins have been implicated in cytotoxic granule

114 Synaptotagmin-1 and neuronal SNARE proteins have central roles in evoked synchronous

115 by soluble NSF attachment protein receptor (SNARE) proteins have been difficult to establish because

116 Here, we show that syntaxin 8 (MoSyn8), a Qc-SNARE protein homolog, also plays important roles in gro

117 ic granule exocytosis, the role of vesicular SNARE proteins, i.e., vesicle-associated membrane protei

118 Tomosyn, a soluble R-SNARE protein identified as a binding partner of the Q-S

119 Syntaxin 3 and 4 are apical and basolateral SNARE proteins important for the specificity of vesicle

120 Our results identify Gos28 as an essential SNARE protein in Drosophila photoreceptors and provide m

121 Munc13-1, CAPS1 binds to syntaxin-1, a key t-SNARE protein in neurosecretion.

122 Intracellular membrane fusion requires SNARE proteins in a trans-complex, anchored to apposed m

123 tudy of MoSyn8 advances our understanding of SNARE proteins in effector secretion which underlies the

124 een implicated in regulating the function of SNARE proteins in exocytosis, but their precise mode of

125 ngs demonstrate for the first time a role of SNARE proteins in HIV-1 assembly and release, likely by

126 e local interactions of fluorescently tagged SNARE proteins in live cells.

127 Botulinum neurotoxins (BoNTs) cleave SNARE proteins in motor neurons that inhibits synaptic v

128 potently inhibit exocytosis by sequestering SNARE proteins in nonfusogenic complexes.

129 interaction of positively charged regions in SNARE proteins in synaptic or secretory vesicle membrane

130 bilayers with positively charged regions in SNARE proteins in the plasma membrane lipid bilayer to f

131 ensitive factor attachment protein receptor (SNARE) proteins in cytotoxic lymphocytes.

132 osed for the transmembrane regions (TMRs) of SNARE proteins, including formation of channel-like tran

133 olemma, as the response was prevented by the SNARE protein inhibitor N-ethylmaleimide and the calcium

134 rescence microscopy, cell fractionation, and SNARE protein interaction studies that acinar cells cont

135 t can generate new biological insight of the SNARE protein interactions in plant cells.

136 thylmaleimide attachment protein receptor (t-SNARE) protein, interferes with VEGFR2 trafficking to th

137 mbly, with continuous generation of reactive SNARE-protein intermediates.

138 membrane (-v) SNARE and target membrane (t-) SNARE proteins into separate liposome populations.

139 eimide-sensitive factor attachment receptor (SNARE) proteins into a parallel four-helix bundle to dri

140 42 targeted the GHRH receptor and depleted a SNARE protein involved in GH exocytosis, vesicle-associa

141 Thus, the fusogenic F protein resembles SNARE proteins involved in vesicle fusion by having wate

142 mammalian horizontal cells along with other SNARE proteins is consistent with vesicular exocytosis.

143 domain, but whether Munc13-4 interacts with SNARE proteins is unknown.

144 al-associated protein of 25 kDa (SNAP-25), a SNARE protein, is functionally relevant to PKC-dependent

145 binding is specific for a subset of exocytic SNARE protein isoforms and requires membrane integration

146 s exocytotic processes mediated by different SNARE protein isoforms, we systematically analyzed the i

147 lexin binding are regulated by the different SNARE protein isoforms.

148 plexes composed of different combinations of SNARE protein isoforms.

149 ed of exocytosis, but total vesicle numbers, SNARE protein levels, and postsynaptic densities remaine

150 Evaluation of SNARE protein localization in activated platelets using

151 Syntaxin 3 (Stx3), a SNARE protein located and functioning at the apical plas

152 endent on the formation of complexes between SNARE proteins located at the target membrane and on tra

153 thesize that taste cell synapses utilize the SNARE protein machinery syntaxin, SNAP-25, and synaptobr

154 ow that lipid-anchored STX11 and its cognate SNARE proteins mainly support exchange of lipids but not

155 We hypothesize that SNARE proteins mediate fusion events at the chlamydial i

156 In platelets, SNARE proteins mediate the membrane fusion events requir

157 to represent the cytotoxic granule vesicular SNARE protein mediating exocytosis in mice.

158 SNAP-25 is a Q-SNARE protein mediating exocytosis of neurosecretory ves

159 in 1/SNAP-25 as the ubiquitous and essential SNARE proteins mediating multiple fusion events on neuro

160 Among SNARE proteins mediating synaptic vesicle fusion, syntax

161 resynaptic compartments, but does not cleave SNARE proteins nor impair spontaneous neurotransmitter r

162 hat otoferlin interacts with two main target-SNARE proteins of the hair-cell synaptic complex, syntax

163 The stimulatory effect of the SNARE protein on the endocytosis of the channel was abol

164 However, discrete effects of SNARE proteins on synaptic function have been difficult

165 sential processes require the interaction of SNARE proteins on vesicle and cell membranes, as well as

166 erlin and synaptotagmin bind membrane fusion SNARE proteins, only otoferlin interacts with the L-type

167 r vesicle-associated membrane protein type v-SNARE proteins (or synaptobrevins) reveals characteristi

168 ng is driven by the assembly of heterologous SNARE proteins orchestrated by the binding of Sec1/Munc1

169 SNARE proteins play a critical role in intracellular mem

170 SNARE proteins play a crucial role in intracellular traf

171 SNARE proteins play indispensable roles in membrane fusi

172 ensitive factor attachment protein receptor (SNARE) proteins play a major role in membrane fusion and

173 SNARE proteins promote membrane fusion by forming a four

174 issociation times and interaction energy for SNARE protein-protein interactions.

175 um-sensitive scaffolding protein, localizing SNARE proteins proximal to the calcium channel so as to

176 pends on endosomal fusion events mediated by SNARE proteins, Rab-GTPases, and multisubunit tethering

177 How and in what form interacting SNARE proteins reach their sites of action is virtually

178 Vesicle SNARE (v-SNARE) proteins reconstituted into giant vesicles ( appr

179 Our results indicate the locus of SNARE protein recycling in presynaptic terminals and rev

180 document a postsynaptic action of this major SNARE protein relevant to synaptic plasticity.

181 lar junction by cleaving SNAP-25, one of the SNARE proteins required for exocytosis.

182 livery of large stoichiometric quantities of SNARE proteins required for forming the partitioning mem

183 n at least three respects: 1) The density of SNARE proteins required for fusion in vitro is substanti

184 re highly potent toxins that cleave neuronal SNARE proteins required for neurotransmission, causing f

185 interactions of CAPS with each of the three SNARE proteins required for vesicle exocytosis.

186 supernatants, indicating that extracellular SNARE proteins retain their ability to bind one another.

187 ensitive factor attachment protein receptor (SNARE) proteins, Sec17p, Sec18p, the Rab Ypt7p, and the

188 The SNARE protein Sec22 contains a signal that binds the COP

189 Here we monitored interactions of the R-SNARE protein Sec22 through a cysteine scanning approach

190 fection there is noncanonical pairing of the SNARE protein Sec22b on ER-derived vesicles with plasma

191 unit Sec6 directly bound the plasma membrane SNARE protein Sec9 in vitro and that Sec6 inhibited the

192 een the Sec6 subunit and the plasma membrane SNARE protein Sec9.

193 We have previously characterized two SNARE proteins, secretory protein (MoSec22) and vesicle-

194 nown whether transmembrane domains (TMDs) of SNARE proteins serve mechanistic functions that go beyon

195 studies have indicated that the gene for the SNARE protein SNAP-25 is a candidate susceptibility gene

196 is by enzymatically cleaving the presynaptic SNARE protein SNAP-25, which results in lasting inhibiti

197 SPalpha) functions as a co-chaperone for the SNARE protein SNAP-25.

198 age-dependent redistribution of the synaptic SNARE proteins SNAP-25, syntaxin-1 and synaptobrevin-2,

199 Inhibiting the function of two key SNARE proteins, SNAP-25 and syntaxin 4, also eliminated

200 for FcepsilonRI-triggered association of the SNARE protein SNAP23 with the SGs.

201 aptotagmin-1 (Syt-1) and indirectly with the SNARE proteins SNAP25 and Syntaxin (Stx-1).

202 ensitive factor attachment protein receptor (SNARE) proteins soluble N-ethylmaleimide-sensitive facto

203 dding (COPII) detected by the packaging of a SNARE protein (soluble N-ethylmaleimide-sensitive attach

204 ng exocytosis, directly interacts with the t-SNARE protein Sso2.

205 ect is mediated by the binding of Mig-6 to a SNARE protein STX8, a protein known to be required for l

206 c domain (BoNT E) in complex with SNAP-25 (a SNARE protein) substrate peptide Arg(180)-Ile(181)-Met(1

207 However, insertion of early endosomal SNARE proteins suffices to convert liposomes into traffi

208 The previously reported interactions with SNARE proteins suggested the involvement of septins in e

209 py (EM) studies indicated that the vesicular SNARE protein synaptobrevin (syb) was dispensable for do

210 The neuronal vesicular SNARE protein synaptobrevin 2 (syb2) is anchored in the

211 In contrast, C2F did not bind the vesicle SNARE protein synaptobrevin-1 (VAMP-1).

212 In contrast, the R-SNARE protein synaptobrevin-2/VAMP2 contributes to both

213 Neurotransmitter release is mediated by the SNARE proteins synaptobrevin II (sybII, also known as VA

214 e factor attachment protein (SNAP) receptor (SNARE) proteins synaptobrevin 2, syntaxin-1A, and SNAP-2

215 Moreover, a juxtamembranous mutation in the SNARE-protein synaptobrevin-2, which presumably impairs

216 cally, alpha-synuclein directly bound to the SNARE-protein synaptobrevin-2/vesicle-associated membran

217 sm by alpha-latrotoxin requires the synaptic SNARE-proteins synaptobrevin/VAMP and SNAP-25, and, at l

218 ors; and the exocytosis machinery, including SNARE proteins (synaptobrevin, SNAP25, and syntaxin), is

219 The TMD of the SNARE protein synaptobrevin2/VAMP2 contains two highly c

220 eading candidate for such a regulator is the SNARE protein syntaxin 1A (Syn1A), previously found to i

221 direct interaction with PI3P, rhodopsin, and SNARE protein syntaxin 3.

222 n secretory dysfunction, we identified the t-SNARE protein Syntaxin 4 as a target of modification by

223 demonstrate the involvement of a CAL-binding SNARE protein syntaxin 6 (STX6) in this process.

224 eptor (SNARE)-mediated process, and that the SNARE protein syntaxin binds directly to Kv2.1 channels.

225 smitter release and requires that the target-SNARE protein syntaxin-1 switches from a closed to an op

226 The core SNARE protein syntaxin-1a (syn1a) was expressed by murin

227 The endosomal SNARE protein syntaxin-8 interacts with the acid-sensiti

228 the enigmatic protein Munc18 that binds the SNARE protein Syntaxin.

229 Y1 is known to interact with the ER-specific SNARE proteins Syntaxin 17 and 18, however only Syntaxin

230 Furthermore, the SNARE proteins syntaxin 1A and SNAP-25 were unable to mo

231 direct interaction between dysferlin and the SNARE proteins syntaxin 4 and SNAP-23.

232 chment protein receptor (SNARE) complexes by SNARE proteins syntaxin-1 (Stx1), synaptosomal-associate

233 between the neuronal SM protein Munc18-1 and SNARE proteins syntaxin-1 and SNAP-25 (25 kDa synaptosom

234 overns neurotransmitter release includes the SNARE proteins syntaxin-1, SNAP-25 and synaptobrevin, wh

235 AMPAR exocytosis, we demonstrate that the Q-SNARE proteins syntaxin-3 and SNAP-47 are required for r

236 r of accessibility of the target membrane (t-SNARE) protein syntaxin 4 to participate in SNARE core c

237 ensitive factor attachment protein receptor (SNARE) protein syntaxin-1 adopts a closed conformation w

238 ensitive factor-attachment protein receptor (SNARE) protein syntaxin-1 exhibits two conformations tha

239 ensitive factor attachment protein receptor (SNARE) protein Syntaxin-1.

240 e factor attachment protein (SNAP) receptor (SNARE) proteins syntaxin-1, SNAP-25, and synaptobrevin/V

241 c18-1 protein and its binding partner, the t-SNARE-protein Syntaxin-1, by approximately 30% and decre

242 ilamellar vesicles containing preassembled t-SNARE proteins (syntaxin 1.SNAP-25), we determined how M

243 ensitive factor attachment protein receptor (SNARE) proteins (syntaxin, synaptosomal-associated prote

244 (i) stabilizing and trafficking the central SNARE protein, syntaxin-1 (i.e. chaperoning function), b

245 Exogenous expression of other homologous SNARE proteins, syntaxin 2/3/4 and SNAP-23, which are re

246 n activity-dependent redistribution of the t-SNARE proteins, SYNTAXIN and SNAP-25, away from neurotra

247 ed for mammalian regulated exocytosis: three SNARE proteins, syntaxin, SNAP-25, and synaptobrevin, an

248 to evaluate the contribution of the neuronal SNARE protein Syntaxin1 (Stx1) in vesicle docking, primi

249 ation of both Atg9 and the autophagy-related SNARE protein syntaxin17 with the autophagosome remained

250 interacts with a closed conformation of the SNARE protein syntaxin1a (Syx1a) and with an assembled S

251 ng full-length and truncation mutants of the SNARE proteins syntaxin1A, SNAP-25B, and synaptobrevin2,

252 The SNARE protein syntaxin4 (Stx4) is involved in the format

253 Here we report that the SNARE protein SYP121 (SYR1/PEN1), which mediates vesicle

254 urthermore, we show that the target membrane SNARE protein SYX-5 colocalizes with a constitutively ac

255 Tomosyn is a 130-kDa cytosolic R-SNARE protein that associates with Q-SNAREs and reduces

256 it was shown that PI(4,5)P2and syntaxin 1, a SNARE protein that catalyzes regulated exocytosis, form

257 ically modifying LCs to target a nonneuronal SNARE protein that extends therapeutic potential for tre

258 d that Bves directly interacts with VAMP3, a SNARE protein that facilitates vesicular transport and s

259 ceptions, such as SNAP-25, a neuron-specific SNARE protein that is essential for synaptic vesicle rel

260 aining vesicles and binds to syntaxin 4, a t-SNARE protein that regulates fusion of transport vesicle

261 s that Syn-2 could function as an inhibitory SNARE protein that, when relieved, could promote exocyto

262 hand-off" in channel control between the two SNARE proteins that is woven together with vesicle fusio

263 ensitive factor attachment protein receptor (SNARE) protein that is known to participate in the regul

264 e-attached (t-SNARE) and vesicle-attached (v-SNARE) proteins that zipper together to form a coiled-co

265 thought to act primarily through one type of SNARE protein, the syntaxins.

266 oxins (BoNTs) are zinc proteases that cleave SNARE proteins to elicit flaccid paralysis by inhibiting

267 ctivating syntaxin-4 (STX-4) to bind cognate SNARE proteins to form a SNARE complex that mediates exo

268 opportunities for in vitro investigations of SNARE proteins to improve our understanding of their rol

269 e neurotoxins are zinc proteases that cleave SNARE proteins to inhibit synaptic vesicle fusion to the

270 ate that syntaxin 1 and SNAP-25 cooperate as SNARE proteins to support neuron survival.

271 is essential for eukaryotic life, requiring SNARE proteins to zipper up in an alpha-helical bundle t

272 pulling the transmembrane regions (TMRs) of SNARE proteins together, thus allowing their TMRs to for

273 The surface density of SNARE proteins turns out to be the most critical paramet

274 Here we show that the v-SNARE protein Vamp-7 is associated with Lamp-1(+) lysoso

275 our results reveal that B-cells rely on the SNARE protein Vamp-7 to promote the local exocytosis of

276 Fusion is mediated by trans complexes of the SNARE proteins VAMP-2, syntaxin-1, and SNAP-25 that brid

277 ytes, where it interacts with a post-Golgi v-SNARE protein, VAMP1, and acetylated microtubules.

278 COOH of nephrin interacts with the vesicular SNARE protein VAMP2 in vitro and ex vivo (using yeast-2

279 The vesicle SNARE proteins VAMP2 (vesicle associated membrane protei

280 from DA-IPC varicosities, but the vesicular SNARE protein, vamp2, was present in a fraction of those

281 mission, whereas the structurally homologous SNARE protein VAMP4 selectively maintains bulk Ca(2+)-de

282 L1 precursor homotypic fusion depends on the SNARE protein VAMP7 together with partner SNAREs.

283 The SNARE protein Vamp7B was mislocalized and enriched on th

284 on process is mediated by a conserved set of SNARE proteins: vesicular synaptobrevin and plasma membr

285 w mutant allele of VTI11 that implicates the SNARE protein VTI11 in homotypic fusion of protein stora

286 The SNARE protein vti1a is proposed to drive fusion of intra

287 s or to liposomes containing PI(4,5)P2 and Q-SNARE proteins was mainly dimer.

288 Studies with recombinant SNARE proteins were used to determine the specific cleav

289 a Rab GTPase, a large Rab effector complex, SNARE proteins which can form a 4-helical bundle, and th

290 ng to SNAREs and the Habc domain of the Vam3 SNARE protein, which may explain its function during fus

291 , the HIV-1 glycoprotein 41 and the synaptic SNARE proteins, which involved transitions between two a

292 nderlying initial plasma membrane contact by SNARE proteins, which subsequently become palmitoylated

293 cles with the plasma membrane is mediated by SNARE proteins, which transfer a force to the membranes.

294 ve fusion (NSF) attachment protein receptor (SNARE) proteins, which promote fusion of synaptic vesicl

295 We site-specifically labeled recombinant SNARE proteins with a FRET donor and acceptor before mic

296 ely charged amino acids of secretory vesicle SNARE proteins with similar domains of plasma membrane S

297 rified fraction selectively cleave essential SNARE proteins within exocrine pancreatic tissue.

298 se flaccid paralysis through the cleavage of SNARE proteins within motor neurons.

299 elicit flaccid paralysis through cleavage of SNARE proteins within peripheral neurons.

300 Vesicular and target membrane-localized SNARE proteins zipper up into an alpha-helical bundle th