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1                                              SPA also significantly attenuated the growth of HPAF-II
2                                              SPA and the observed stable nonlinear spectral propagati
3                                              SPA inhibited CXCR2-mediated Ca(2+) mobilization and blo
4                                              SPA is known to be critical for proper assembly of the i
5                                              SPA loss-of-function phenotypes include excessive septat
6                                              SPA proteins are essential cofactors of COP1, but their
7                                              SPA proteins are not homologous at the primary sequence
8                                              SPA showed a capacity to appropriate circulating IgG, by
9                                              SPA uses a universal plasmid donor strain that contains
10                                              SPA versus PPA changes were significant at the SZ and TZ
11                                              SPA-1 localizes to the cytoplasm and to a lesser degree
12                                              SPA-LDA and PCA-LDA provided significantly better result
13                                              SPA-LN is optimized by maximizing both the affinity and
14                                              SPA-TT(2) elicited slightly higher, though not statistic
15 -induced proliferation-associated protein 1 (SPA-1), as a factor that interacts with Brd4.
16  (COP1) and SUPPRESSOR OF PHYTOCHROME A-105 (SPA)1 in vitro.
17 OMORPHOGENIC1 (COP1)/SUPPRESSOR OF phyA-105 (SPA) complex, which targets positive regulators of photo
18 1 and RUP2), and the SUPPRESSOR OF PHYA-105 (SPA) family as proteins copurifying with UVR8(W285A).
19                      SUPPRESSOR OF PHYA-105 (SPA) proteins are known to work in concert with COP1, an
20 the COP1-interacting SUPPRESSOR OF PHYA-105 (SPA) proteins in seedling and adult facets of the shade-
21 jection although BDNF had no effect on 0-24h SPA and aEE.
22     Circular dichroism revealed that a 29mer SPA peptide shifts from a random coil to a helix in a co
23      Under optimized conditions, the IGFBP-4 SPA was stable for up to 24h at room temperature and was
24 apture 125I-labeled hIL-5-bound Sf9 cells, a SPA was developed and used to measure hIL-5 high-affinit
25 y the silanized fiber surface thus forming a SPA layer, which would greatly enhance the proportion of
26 icacy and safety of sulcus implantation of a SPA-IOL, designed for both in-the-bag and sulcus positio
27 H inhibitors can be readily detected using a SPA with BMACP and that the effectiveness of inhibitors
28 i (ST) and S. enterica serotype Paratyphi A (SPA) isolates were included.
29  COP1 acts with SUppressor of phytochrome A (SPA) proteins.
30 e release of the virulence factor protein A (SPA) from a strain of community-associated methicillin-r
31 RA, the ability of staphylococcal protein A (SPA) to interact with and modulate cells of the monocyti
32                    Staphylococcal protein A (SPA) was used to modify the silanized fiber surface thus
33                        Surfactant protein A (SPA), a lung-specific collectin, stimulates macrophage c
34 put method called selective ploidy ablation (SPA).
35  of sinusitis-related subperiosteal abscess (SPA) of the orbit and their impact on patient outcomes u
36                  Slow population activities (SPAs) exist in the brain and have frequencies below ~5 H
37 rom increased spontaneous physical activity (SPA) and resting metabolic rate (RMR); and 3) if VMH BDN
38 nditure (EE), spontaneous physical activity (SPA), postintervention diet-induced thermogenesis (DIT),
39 sheep known as sheep pulmonary adenomatosis (SPA; ovine pulmonary carcinoma).
40  cover (MSSC) and the sum-product algorithm (SPA).
41 hm (GA), a successive projections algorithm (SPA) and nonlinear techniques (BP-ANN, back propagation
42            Successive projections algorithm (SPA) was used to select the most important wavelengths f
43 ction effect, self-parametric amplification (SPA), which manifests itself as optical spectrum narrowi
44 llant-impregnated microspheres, generates an SPA signal.
45 vity of compound 33 is 95 nM for eIF4E in an SPA binding assay.
46 be2L3 (UbcH5a and UbcH7) established that an SPA motif in loop 7 of E2 is required for binding to CHI
47                In spatial ancestry analysis (SPA), we explicitly model the spatial distribution of ea
48 ssociated with Linear Discriminant Analysis (SPA-LDA) for simultaneous classification of the teas acc
49 ating that a proper balance between Brd4 and SPA-1 in G2 is required for cell division.
50 cence complementation revealed that Brd4 and SPA-1 interact with each other in the nucleus of living
51  on COL12 and show that COL12 binds COP1 and SPA proteins in vivo.
52  best results were obtained for U-PLS-DA and SPA-LDA with 76% and 80% accuracy.
53 ms evaluated were SIMCA, N- and U-PLS-DA and SPA-LDA.
54 methyleneanilinouracil by the filtration and SPA methods gave comparable results, but the SPA assay u
55 , carbon dioxide production, food intake and SPA were measured for 24h in an indirect calorimeter.
56 dixic acid and ciprofloxacin for both ST and SPA.
57  parallel urine samples collected by TUC and SPA were similar.
58 hyB disrupt the interaction between COP1 and SPAs, resulting in reorganization of the COP1/SPA comple
59 he substance P receptor (NK(1)R) antagonist (SPA) L-000760735 altered cortical expression of multiple
60 completeness of the superficial palmar arch (SPA) was present in 46%, the deep palmar arch was comple
61 ep zone [DZ]) and regions (subpistonal area [SPA] and peripistonal area [PPA]) were defined as region
62 sent here a new two-hybrid smart pool array (SPA) system in which, instead of individual activation d
63    We developed a scoring function (named as SPA-PP, specificity and affinity of the protein-protein
64  and urine collected by suprapubic aspirate (SPA), regardless of whether the subjects had urinary sym
65 onfirmed in a scintillation proximity assay (SPA) and a DEAE membrane-based assay for [(3)H]AAG bindi
66 l assay using scintillation proximity assay (SPA) beads and a scintillation plate counter.
67  (WGA)-coated scintillation proximity assay (SPA) beads to capture 125I-labeled hIL-5-bound Sf9 cells
68 avidin-coated scintillation proximity assay (SPA) beads, and after addition of homopolymeric A templa
69 rst validated scintillation proximity assay (SPA) binding method for quantitation of (3)H-labeled d-l
70  of a coupled scintillation proximity assay (SPA) for 3 KDMs: KDM1A (LSD1), KDM3A (JMJD1A), and KDM4A
71 A homogeneous scintillation proximity assay (SPA) for detection of RNA transcripts is described.
72 , homogeneous scintillation proximity assay (SPA) for DGAT.
73 96-well plate scintillation proximity assay (SPA) for measuring small molecule interactions at IGFBP-
74 gh-throughput scintillation proximity assay (SPA) for parathyroid hormone (1-84) (PTH) has been devel
75 e developed a scintillation proximity assay (SPA) for PARP.
76 l homogeneous scintillation proximity assay (SPA) for the study of DnaB-stimulated E. coli primase ac
77 AH) using the scintillation proximity assay (SPA) technology is described.
78  based on the scintillation proximity assay (SPA) technology that provides results equivalent to thos
79 s: the use of scintillation proximity assay (SPA) technology to measure aminoacyl-tRNA synthetase (aa
80 d optimized a scintillation proximity assay (SPA) to replace the more costly, wasteful and cumbersome
81             A scintillation proximity assay (SPA) was developed to detect phosphatidylinositol 3-kina
82 e developed a scintillation proximity assay (SPA) where use of biotinylated MACP (BMACP) allows the g
83 measured in a scintillation proximity assay (SPA)-based high-throughput screen using [gamma-(33)P]bio
84 leosomes in a scintillation proximity assay (SPA).
85 hy (IMAC) and scintillation proximity assay (SPA).
86 l homogeneous scintillation proximity assay (SPA).
87 intillation proximity high throughput assay (SPA) to identify inhibitors of DNA methyltransferases wa
88 tected only by sensitive solid-phase assays (SPAs) on renal transplant outcomes is unclear.
89 is based on a novel short peptide assembler (SPA) that assembles protein sequences from their constit
90  the form of synchronous plateau assemblies (SPAs) that are initiated by sparse groups of gap-junctio
91  These 24 residues comprise the SP assembly (SPA) domain, and we propose that neighboring SPA units i
92 ), databases, service provision assessments (SPAs), Demographic and Health Surveys, Multiple Indicato
93 cter, we identify 17 septal pore-associated (SPA) proteins that localize to the septal pore in rings
94  ecosystem model (the Soil-Plant-Atmosphere (SPA) model) were evaluated against measurements from two
95 n microscopy with single-particle averaging (SPA-SIM) approach to study the localization of all 18 SP
96 type of in vitro GABAergic, inhibition-based SPA exhibited by C57BL/6 murine hippocampus.
97 e compared to the solution-phase or off-bead SPA.
98                            Anti-TLR2 blocked SPA-induced production of TGFbeta.
99  increasing trend in enteric fever caused by SPA during the last 2 decades (P < .01).
100 suggest that cry2 stability is controlled by SPA and phyA, thus providing more information on the mol
101     Histone deacetylase activity measured by SPA was concordant with that determined via the traditio
102 , cell-surface ATP concentration measured by SPA-luc transiently reached approximately 1 microm indep
103 the regulation of innate immune responses by SPA with key roles for specific components of the extrac
104 y polyvinyl toluene-polyethyleneimine-coated SPA beads and quantified by counting by beta-scintograph
105 e signal upon binding to streptavidin-coated SPA beads.
106 ds, were even more effective than WGA-coated SPA beads for capturing the insect cells.
107  yellow-colored compounds, than conventional SPA beads or scintillation fluid (emitting at 400 to 480
108 dark by the synergistic actions of CUL4(COP1-SPA) E3 ubiquitin ligase and a subset of basic helix-loo
109             Here, we show that the CUL4(COP1-SPA) E3 ubiquitin ligase is necessary for the light-indu
110 EBF1/2), CUL3(LRB), CUL3(BOP), and CUL4(COP1-SPA)) that regulate PIF abundance both in dark and light
111 enic factor targeted for degradation by COP1/SPA, correlates temporally with the accumulation of phyA
112  the mechanism by which they inactivate COP1/SPA is still unknown.
113                       Light inactivates COP1/SPA, in part by excluding COP1 from the nucleus.
114  the Arabidopsis (Arabidopsis thaliana) COP1/SPA E3 ubiquitin ligase causes the degradation of multip
115  The Arabidopsis (Arabidopsis thaliana) COP1/SPA ubiquitin ligase is a central repressor that suppres
116                         We propose that COP1/SPA activity, via LONG HYPOCOTYL IN FR LIGHT1, is requir
117 r mechanism for the inactivation of the COP1/SPA complex by phyA- and phyB-mediated light perception.
118 PAs, resulting in reorganization of the COP1/SPA complex in planta.
119 pa mutants, thus demonstrating that the COP1/SPA complex is only required for elongation responses to
120 rs of COP1, but their exact role in the COP1/SPA complex is thus far unknown.
121                Phytochromes inhibit the COP1/SPA complex, leading to the accumulation of transcriptio
122 lated phyA from being recognized by the COP1/SPA complex.
123 cating that COL12 is a substrate of the COP1/SPA ubiquitin ligase.
124 ow R:FR, in a fashion that involves the COP1/SPA ubiquitination target LONG HYPOCOTYL IN FR LIGHT1 bu
125                       Appropriately designed SPA-IOL may be implanted in the ciliary sulcus during ph
126                                      Despite SPAs being prominent in several cortical areas and servi
127 atistical values also indicate that the DGAT SPA is a robust assay, with a Z' of more than 0.60 and a
128 n kinetic parameters determined by this DGAT SPA method agreed well with the values determined with t
129 gnificantly, levels of IgG anti-LPS than did SPA-TT(1) in these age groups.
130 drazide as a linker (SPA-TT(1)) or directly (SPA-TT(2)).
131 Instead, the spacer peptide assembly domain (SPA), a putative 24-residue helical sequence comprising
132 X-2 of nonsteroidal anti-inflammatory drugs, SPA successfully discriminates the drugs from the divers
133  and may be reflective of more AMR among DSA-SPA-positive patients.
134  and may be reflective of more AMR among DSA-SPA-positive patients.
135  was similar in the DSA-SPA-positive and DSA-SPA-negative groups (log-rank test=0.63, P=0.428).
136  was similar in the DSA-SPA-positive and DSA-SPA-negative groups (log-rank test=0.63, P=0.428).
137     Patients in the DSA-SPA-positive and DSA-SPA-negative groups received similar immunosuppression,
138     Patients in the DSA-SPA-positive and DSA-SPA-negative groups received similar immunosuppression,
139 tibodies detected by solid-phase assays (DSA-SPA) may contribute to the worse prognosis.
140 tibodies detected by solid-phase assays (DSA-SPA) may contribute to the worse prognosis.
141 19 patients, including 145 with isolated DSA-SPA.
142                         The influence of DSA-SPA on repeat renal transplantation outcomes has not bee
143                         The influence of DSA-SPA on repeat renal transplantation outcomes has not bee
144 ese studies suggest that the presence of DSA-SPA, despite a negative flow cytometry crossmatch result
145 hese included 62 patients with preformed DSA-SPA detected by Luminex at the time of transplantation.
146 hese included 62 patients with preformed DSA-SPA detected by Luminex at the time of transplantation.
147                Recipients with preformed DSA-SPA had higher rejection rates (54.8% vs. 34.8%, P=0.01)
148                Recipients with preformed DSA-SPA had higher rejection rates (54.8% vs. 34.8%, P=0.01)
149              This analysis suggests that DSA-SPA increases the overall risk of acute rejection but do
150              This analysis suggests that DSA-SPA increases the overall risk of acute rejection but do
151 ll allograft survival was similar in the DSA-SPA-positive and DSA-SPA-negative groups (log-rank test=
152 ll allograft survival was similar in the DSA-SPA-positive and DSA-SPA-negative groups (log-rank test=
153                          Patients in the DSA-SPA-positive and DSA-SPA-negative groups received simila
154                          Patients in the DSA-SPA-positive and DSA-SPA-negative groups received simila
155 7, P=0.02) as compared to those who were DSA-SPA-positive and FCXM-negative.
156 7, P=0.02) as compared to those who were DSA-SPA-positive and FCXM-negative.
157                      Recipients who were DSA-SPA-positive and flow cytometry crossmatch (FCXM)-positi
158                      Recipients who were DSA-SPA-positive and flow cytometry crossmatch (FCXM)-positi
159             BDNF increased SPA and EE during SPA (aEE) within 9h after injection although BDNF had no
160  These data support the proposal that the E2 SPA motif provides specificity for binding to CHIP, wher
161  studies, 46 HAI national surveys, and eight SPAs.
162 LTR poly(A) signal with a synthetic element (SPA) permits gene loop formation, suggesting that these
163 igh-throughput screening utilizing an ERbeta SPA-based binding assay.
164 pressed in both naturally and experimentally SPA-affected sheep.
165 RSA skin abscess all contained extracellular SPA.
166  safety profile and relative risks of [(18)F]SPA-RQ with 3 different methods of image analysis.
167 nce P antagonist-receptor quantifier ([(18)F]SPA-RQ) [2-fluoromethoxy-5-(5-trifluoromethyl-tetrazol-1
168 on of 192 +/- 7 MBq (5.2 +/- 0.2 mCi) [(18)F]SPA-RQ.
169                                       A FabH SPA adaptable to high-throughput screening should facili
170 HDA-2 histone deacetylase-associated factor, SPA-19.
171 ct classification rate) were 96% and 98% for SPA-LDA and PLS-DA, respectively, indicating that the NI
172        We have uncovered a novel pathway for SPA-stimulated macrophage chemotaxis where SPA stimulati
173 dium, suggesting a COP1-independent role for SPA proteins.
174 ad a 33% sensitivity and 86% specificity for SPA incompleteness with a cutoff value of >10 seconds an
175               We show that COP1 and the four SPA genes are essential for hypocotyl and leaf petiole e
176 GABAergic interneurons as they progress from SPAs to GDPs marks the emergence of synapse-driven netwo
177                                     Further, SPA-releasing chemokines were present in mouse skin lesi
178 is method, a Saccharomyces cerevisiae genome SPA increases yeast two-hybrid screening efficiency by a
179 [gamma-(33)P]biotin-11 GTP as substrate (GTP-SPA); the format is sensitive, accurate, robust, and com
180                   The performance of the GTP-SPA and RNA assays was tested against a panel of commerc
181                                       Hence, SPA proteins are necessary for the light-controlled chan
182 fulness in the SS condition and a 19% higher SPA (P = 0.003).
183               In particular, for hippocampal SPAs to occur, we predict that individual fast-spiking i
184 cover mechanisms responsible for hippocampal SPAs.
185            Our results show that hippocampal SPAs are an emergent phenomenon in which the "slowness"
186 ntify characteristics underlying hippocampal SPAs.
187 , to membranes is cooperative and identifies SPA as a major factor that controls this cooperativity.
188        [3H]Inositol phosphates bound to IMAC-SPA beads through the strong interaction of their phosph
189      The classification models were based in SPA-LDA (Linear Discriminant Analysis coupled with Succe
190  examined the role of HA, RHAMM, and CD44 in SPA-stimulated macrophage chemotaxis.
191              A single amino acid mutation in SPA that abrogates assembly in vitro dramatically reduce
192 red affinity tags that are often required in SPA, and is capable of detecting either radiolabeled RNA
193           Most of the amino acid residues in SPA could not be mutated individually without abrogating
194 neurons are engaged more in GDPs and less in SPAs.
195 dividual involvement of GABAergic neurons in SPAs is correlated to their temporal origin.
196 olved in GDPs, interneurons participating in SPAs possess immature intrinsic properties, receive syna
197                               BDNF increased SPA and EE during SPA (aEE) within 9h after injection al
198 ke and increasing EE consequent to increased SPA and RMR, suggesting that the VMH is an important sit
199                               Interestingly, SPA markedly increased apoptosis but moderately decrease
200  of a single-piece-acrylic intraocular lens (SPA-IOL) in the ciliary sulcus during phacoemulsificatio
201 T) with adipic acid dihydrazide as a linker (SPA-TT(1)) or directly (SPA-TT(2)).
202  Staphylococcus aureus protein A-luciferase (SPA-luc) was bound to endogenous antigens on primary hum
203 ng antibody blockade and murine macrophages, SPA-stimulated macrophage chemotaxis was dependent on TL
204                      In primary macrophages, SPA-stimulated TGFbeta production was dependent on TLR2,
205                  We developed a novel method SPA (SPecificity and Affinity) based on our funneled ene
206      Comparable IC(50) values of 160 microM (SPA) and 125 microM were also obtained with the antibiot
207                IC(50) values of 15.2 microM (SPA) and 24.8 microM were obtained with iodoacetamide an
208  of nucleic acid-ligand interactions, namely SPA-LN.
209 SPA) domain, and we propose that neighboring SPA units in a Gag hexamer coalesce to form a six-helix
210                                   This novel SPA has been validated and demonstrated to be simple, se
211 periencing flow degenerate in the absence of SPA-19, suggesting that eddy-trapped nuclei function to
212 teraction, Brd4 enhanced Rap GAP activity of SPA-1.
213                  Moreover, administration of SPA in the early stages of disease substantially allevia
214 RV from an animal with a spontaneous case of SPA (JSRV(21)) and showed that it harbors an infectious
215 tide substrate, ATP ([33P]ATP in the case of SPA), and tyrosine kinase in a 96-well assay format.
216 ameter changes in the entire sample depth of SPA versus PPA were found for delta1/2 (T1rho, 14% +/- 1
217             Here, we examined the effects of SPA in ductal pancreatic cancers that express multiple G
218                 In addition, the efficacy of SPA as a therapeutic agent was evaluated in murine colla
219            Furthermore ectopic expression of SPA-1 and Brd4 redirected subcellular localization of th
220  characterized the structure and function of SPA.
221 fication with PCT and sulcus implantation of SPA-IOL designed for both in-the-bag and sulcus position
222                           The performance of SPA-LN validates the development strategy and provides a
223 n the nucleus in the absence and presence of SPA proteins, indicating that SPA proteins are not requi
224  that this novel dual-inhibitory property of SPA could be of significant therapeutic value in pancrea
225               To unravel a potential role of SPA proteins in COP1 nucleocytoplasmic partitioning, we
226                    Consistent with a role of SPA proteins in phytochrome A (phyA) signaling, a phyA m
227   Thus we describe the tertiary structure of SPA in the presence of sodium dodecylsulfate micelles at
228 hese turns juxtapose the N- and C-termini of SPA and may form the basis of this peptide's unique abil
229                     The benchmark testing of SPA shows the best performance against 16 other popular
230 o found that several lectins, when coated on SPA beads, were even more effective than WGA-coated SPA
231 lasma membrane localization was dependent on SPA.
232 3+), Lu(3+), and Sc(3+), were immobilized on SPA beads via metal chelate and utilized as affinity lig
233 eformed DSAs, defined by positive results on SPA but negative complement-dependent cytotoxicity and f
234                            Accordingly, only SPA-TT(2) was evaluated in the 2- to 4-year-old children
235 chrome B (phyB) interact with SPA1 and other SPA proteins.
236 axis was dependent on TLR2 but not the other SPA receptors examined.
237                                 We apply our SPA method to a European and a worldwide population gene
238 -Arg(1), D-Trp(5,7,9), Leu(11)] substance P (SPA) belongs to a family of peptides including antagonis
239                                         PARP-SPA can be readily adapted to a 96-well format for autom
240 t formed in the reaction binds to polylysine SPA beads, producing a signal that is measured in a TopC
241 the Rap1-specific GTPase-activating protein, SPA-1, or inactivated form of Rap1 (N17Rap1) blocked pho
242 ), including JIA, SLE, CEL, T1D, UC, CD, PS, SPA and CVID, attributable to common genomic variations
243 o streptavidin-coated polyvinyltoluene (PVT) SPA microbeads and using [(125)I]IGF-1 as the endogenous
244 ound) and a chiral spirophosphoric acid ((R)-SPA) in an asymmetric N-H insertion reaction.
245 lling transition states wherein a chiral (R)-SPA protonates a dirhodium-bound enol intermediate.
246 ears requiring surgery for sinusitis-related SPA has remained a minority (15%-32.5%), without a clear
247 nts</=18 years of age with sinusitis-related SPA treated from 2002 to 2012; comparable cohorts from e
248 he cell membrane of CA-MRSA, and the related SPA-releasing chemokine CXCL10 bound to both cell wall a
249 evidence that the light signaling repressors SPA proteins contribute to COP1-mediated phyA degradatio
250 in biosynthesis in vegetative shade requires SPA function.
251 h singlet oxygen to damage oxidant-sensitive SPA components.
252 udied the morphophysiological fate of single SPA cells as a function of development.
253                                         Some SPA proteins form aggregates at the septal pore, and in
254 including [D-Arg(1),D-Trp(5,7,9),Leu(11)]SP (SPA) are broad-spectrum G protein-coupled receptor (GPCR
255                                Subsequently, SPAs are replaced by synapse-driven giant depolarizing p
256                             We conclude that SPA proteins have a dual role: (1) they are required for
257 The remarkable performance demonstrates that SPA has significant potential applications in identifyin
258                   Thus, we hypothesized that SPA proteins could also play a role in cry2 degradation.
259 nd presence of SPA proteins, indicating that SPA proteins are not required for nuclear localization o
260 eature of the results presented here is that SPA markedly reduced tumor-associated angiogenesis in th
261 ailed study of chemokine CXCL9 revealed that SPA release occurred through a post-translational mechan
262                        Our results show that SPA, a broad-spectrum GPCR antagonist attenuates tumor g
263 isons with other scoring functions show that SPA-PP performs remarkably on both predictions of bindin
264 ell line as our model system, we showed that SPA inhibited multiple neuropeptide-induced Ca(2+) mobil
265 fetime imaging microscopy analyses show that SPAs and phytochromes colocalize and interact in nuclear
266                                          The SPA algorithm is based on informed traversals of a de Br
267                                          The SPA format is easily adapted to high-throughput screenin
268                                          The SPA used an antibody to couple glutathione-S-transferase
269 sembled VLPs showed strong protection at the SPA region, consistent with a higher-order structure.
270 SPA methods gave comparable results, but the SPA assay uses less radioactive label, is less time-cons
271 tibodies in the recipient, identified by the SPA, even in the presence of a negative flow cytometry c
272 V2 MAbs were thoroughly dissociated from the SPA layer by treatment with urea, and recombined to the
273 proximity to the scintillant embedded in the SPA beads, thereby allowing the radioactivity to be quan
274 s using intact CHO-Dukx/5-HT(6) cells in the SPA format was similar to data obtained from a filtratio
275  and rank order of potencies obtained in the SPA format were consistent with published filtration dat
276  that the effectiveness of inhibitors in the SPA is comparable to that obtained using MACP and a stan
277 , as determined by Z'=0.81+/-0.017, make the SPA format amenable to automation and higher throughput;
278 s were associated with incompleteness of the SPA (P=0.001 and P=0.001).
279 ive, sensitive high-throughput nature of the SPA format has advanced our knowledge of isoform-specifi
280               Although incompleteness of the SPA is common, digital blood supply is always preserved
281               Finally, incompleteness of the SPA is not associated with a loss of upper-extremity fun
282 hese findings demonstrate the utility of the SPA technique to introduce plasmids into the haploid gen
283         In addition, we demonstrate that the SPA-to-GDP transition is paralleled by a remarkable matu
284 y treatment with urea, and recombined to the SPA layer on the sensor surface for repeated immunoassay
285 hen detected through an interaction with the SPA beads.
286                                         This SPA method has also been successfully used to probe RNA-
287                                         This SPA uses the specific interactions of [3H]R(+)-methanand
288 K(m) of 7.1 microM was determined using this SPA with the Streptomyces glaucescens FabH.
289                                        Thus, SPA-PP is a promising quantification of protein-protein
290  RHAMM(-/-) mice had decreased chemotaxis to SPA, TGFbeta1, and HA.
291 2(-/-) mice failed to migrate in response to SPA but responded normally to TGFbeta1 and HA, effects t
292  and CD44(-/-) mice had similar responses to SPA, whereas those from RHAMM(-/-) mice had decreased ch
293               As proof of principle, we used SPA to transfer plasmids containing wild-type and mutant
294 e of monomer nucleosomes as substrates using SPA technology could lead to more robust screening assay
295                            Association of VH-SPA with Z22VL-SPA restored both the effects of single s
296 r SPA-stimulated macrophage chemotaxis where SPA stimulation via TLR2 drives JNK- and ERK-dependent T
297         A role for these RapGAPs, along with SPA-1, as tumor suppressors has been demonstrated.
298 xtremity dysfunction was not associated with SPA incompleteness (P=0.77).
299 as well as three hydrophilic residues within SPA.
300             Association of VH-SPA with Z22VL-SPA restored both the effects of single substitutions an

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