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1 SRM 1950 is the first reference material developed speci
2 SRM 1950 Metabolites in Human Plasma is intended to have
3 SRM 612 (Trace Elements in Glass) was also analyzed desp
4 SRM 972a was developed in collaboration with the Nationa
5 SRM detection provides the relative quantitation of each
6 SRM domains are then polarized by the microtubule-depend
7 SRM polarization requires F-actin but not the F-actin or
8 al certified reference materials (SRM 1568a, SRM 1570a, CRM 7503-a, BC211 and IPE-120) were analysed
9 ients undergoing active surveillance for 957 SRMs indicates that the majority grew during observation
13 hese methods, biologists have begun adopting SRM to address a wide range of questions in many types o
14 ation outcome was best predicted by advanced SRM stage (hazard ratio, 4.89; P<0.0001) and diabetes me
17 ing risks of mortality, all patients with an SRM should be considered for a biopsy when the results m
20 Hg and Pb in NIST SRM 1547 peach leaves and SRM 1573a tomato leaves reference materials and three he
22 dard reference materials (BCR-482 Licken and SRM 1573a Tomato Leaves) and spiked real food and herb s
23 st, SRM 1650b Diesel Particulate Matter, and SRM 2975 Diesel Particulate Matter (Industrial Forklift)
26 accessory olfactory bulb stimulation before SRM acquisition blocked long-term SRM, supporting the in
28 quential analysis of fractionated eluates by SRM (SAFE-SRM), to plasma from cancer patients and disco
29 ent of these proteins in nuclear extracts by SRM permitted the reproducible quantification of 42% of
32 s Proteotypic Predictor, to select candidate SRM transitions when no previous mass spectrometry evide
33 proteome and its use in selecting candidate SRM peptides to establish assays for use in determining
36 enges are addressed to effectively correlate SRM with other microscopy techniques, including light mi
37 also discuss the application of correlative SRM to materials characterization and single-molecule re
39 ed an antibody-independent deep-dive SRM (DD-SRM) approach that capitalizes on multidimensional high-
45 eveals that the correlation between dimethyl-SRM and SID-SRM is within 0.3-33% variation, demonstrati
48 developed an antibody-independent deep-dive SRM (DD-SRM) approach that capitalizes on multidimension
49 asurements of diagnostic product ions during SRM transitions by ratiometric comparisons with stable i
50 an Particulate Matter, SRM 1649b Urban Dust, SRM 1650b Diesel Particulate Matter, and SRM 2975 Diesel
52 ssociation-selected reaction monitoring (ETD-SRM) was developed to investigate isoAsp sites in MUPs.
53 to selected reaction monitoring experiments (SRM) as it may result in a gain in selectivity in detect
54 fort highlights the development of the first SRM for reduced nicotine and reduced tobacco-specific ni
58 e that experimental conditions optimized for SRM 955c (caprine blood) are not valid for human blood s
70 r the highly selected reaction monitoring (H-SRM) mode, the detection limit of O(2)-edT, N(3)-edT, an
71 thmias (failed ablations) occurred at higher SRM stages with 28 of 133 (21.0%) in stage I, 40 of 140
73 The performance was compared with two IA SRM methods which were recently validated for individual
75 ved to be equivalent to the gold-standard ID-SRM in terms of sensitivity (1-10 ppm), accuracy, and pr
78 actions of interest, significantly improving SRM sensitivity by approximately 5 orders of magnitude w
81 ologists navigate through common pitfalls in SRM specimen preparation and optimization of image acqui
82 ecently we have made significant progress in SRM sensitivity for enabling quantification of low nanog
83 and conventional liquid chromatography (LC)-SRM (45 min gradient) showed that the long-gradient sepa
84 r multiplexing capacity than conventional LC-SRM due to an increase in average peak widths (~3-fold)
87 omatography selected reaction monitoring (LC-SRM) analyses of low-abundance peptides spiked into a hi
88 omatography-selected reaction monitoring (LC-SRM) approach that we demonstrate is capable of quantita
91 metry using selected reaction monitoring (LC/SRM-MS) holds great promise for targeted protein analysi
95 of >0.99 was observed for the results of LG-SRM and enzyme-linked immunosorbent assay (ELISA) measur
100 nt selection of target fractions via on-line SRM monitoring of internal standards, and fraction multi
101 st that the proposed oxygen and LLL12 loaded SRMs provide a promising drug delivery strategy for more
102 which hurdles still need to be taken to make SRM a robust and more accurate method for sFLC measureme
107 : Management options for small renal masses (SRMs) include excision, ablation, and active surveillanc
111 ST) new protein standard reference material (SRM 8671) is becoming the benchmark molecule against whi
114 constitute NIST Standard Reference Material (SRM) 1720 Northern Continental Air, were certified by NI
115 and Technology Standard Reference Material (SRM) 1950, "Metabolites in Frozen Human Plasma", against
116 total sulfur in Standard Reference Material (SRM) 2682c Subbituminous Coal (nominal mass fraction 0.5
117 ) has developed Standard Reference Material (SRM) 972a Vitamin D Metabolites in Frozen Human Serum as
118 tion of a glass standard reference material (SRM) and the Al layer as reference, the deviations betwe
119 tobacco filler Standard Reference Material (SRM) has been issued by the National Institute of Standa
120 has developed a Standard Reference Material (SRM) to support technology development in metabolomics r
122 in a house dust standard reference material, SRM 2585, demonstrating their environmental relevance.
124 alidated using certified reference materials SRM 1570A (spinach leaves) with satisfactory and compati
128 ns of disposing of specified risk materials (SRM) or animal mortalities potentially infected with pri
129 dry whole air standard reference materials (SRMs 1720 and 1721) and the NIST Traceable Reference Mat
130 four powdered standard reference materials (SRMs) fused in lithium borate glasses: two sediments as
132 udy were SRM 1648a Urban Particulate Matter, SRM 1649b Urban Dust, SRM 1650b Diesel Particulate Matte
133 , randomly distributed sterol-rich membrane (SRM) domains form at the plasma membrane, independent of
137 d LLL12 in stimuli responsive microdroplets (SRMs) by a gas-driven coaxial flow focusing (CFF) proces
138 reservoirs, sulfate reducing microorganisms (SRM) produce hydrogen sulfide which is toxic, explosive,
139 respiratory sulfate reducing microorganisms (SRM), and no study has systematically and quantitatively
141 of super-resolution fluorescence microscopy (SRM) opened an unprecedented vista into nanoscopic lengt
144 The rise of super-resolution microscopy (SRM) over the past decade has drastically improved the r
148 used the fugacity-based small-region model (SRM) to calculate predicted environmental concentrations
149 This novel spectral resonance modulator (SRM) shows great potential in an ultrafast compressive s
150 s method using selected reaction monitoring (SRM) aimed at quantitative profiling of the stoichiometr
151 MS assay using selected reaction monitoring (SRM) allows simultaneous quantitation of five molecular
152 SI MS/MS) with selected reaction monitoring (SRM) and quantitation by high mass accuracy analysis of
153 oduce a set of selected reaction monitoring (SRM) assays for the systematic measurement of 464 protei
154 ion (HRMS) and selected reaction monitoring (SRM) based mass spectrometric detection to quantify a po
156 ort the use of selected reaction monitoring (SRM) for tracking proteolysis induced by human apoptotic
157 time-triggered selected reaction monitoring (SRM) in positive electrospray ionization (ESI) mode.
160 that utilizing selected reaction monitoring (SRM) mass spectrometry allows researchers to confirm pro
161 f principle, a selected reaction monitoring (SRM) mass spectrometry-based methodology was applied to
163 ometry (MS) in Selected Reaction Monitoring (SRM) mode is proposed for in-depth characterisation of m
164 re detected in selected reaction monitoring (SRM) mode, and transition m/z 874.3 --> 778.3 was used f
168 n SPROX using selective reaction monitoring (SRM) on a triple quadrupole mass spectrometer (QQQ-MS).
169 he upcoming LC-selected reaction monitoring (SRM) technique which combines high technical accuracy wi
170 erences in the selected reaction monitoring (SRM) transition of the signature peptide due to the incr
171 ing different selective reaction monitoring (SRM) transitions or adding more labeling positions.
172 Similarly to selected reaction monitoring (SRM), peptides can be quantified from DIA data using tar
173 is the use of selected reaction monitoring (SRM), where the areas under the curve (AUCs) of peptides
174 performed by selective reaction monitoring (SRM), while the presence of a product ion at m/z 355, sp
175 ere describe a selected reaction monitoring (SRM)-based approach for the discovery and validation of
176 We applied selected reaction monitoring (SRM)-based proteomics, profiling 43 proteins in serum pr
177 rt an extended selected reaction monitoring (SRM)-based strategy to reproducibly and quantitatively m
182 teomics (e.g., selected reaction monitoring, SRM) is emerging as an attractive alternative to immunoa
186 l protein identification technology (MudPIT)-SRM, taking advantage of the robust online strong cation
191 sis of LGC 6010 Hard drinking water and NIST SRM 1573a Tomato leaves standard reference materials.
194 -611) low level bromide in groundwater, NIST SRM 1568b Rice Flour, and SRM 1632 bituminous coal.
195 e determination of As, Cd, Hg and Pb in NIST SRM 1547 peach leaves and SRM 1573a tomato leaves refere
197 ternational standard reference material NIST SRM 977 (delta(81)BrSMOB = -0.65 +/- 1.1 per thousand, 1
199 d using a certified reference material (NIST SRM 1643e) and groundwater sample analysis, indicating t
200 Technology Standard Reference Material (NIST SRM) 2779 Gulf of Mexico crude oil by GC coupled to vacu
201 lyses of certified reference materials (NIST SRM 1515 Apple leaves, IAEA 336 Lichen, GBW 07605 Tea).
202 nalysing certified reference materials; NIST SRM 1515 Apple leaves, IAEA-336 Lichen and GBW-07605 Tea
203 o that of the bone mineral component of NIST SRM 1486 (bone meal), as determined by powder X-ray diff
205 , we have performed global profiling of NIST SRM 1950, "Metabolites in Human Plasma", using GC-MS, LC
206 the certified values in the analysis of NIST SRM 955c (Caprine Blood) Level 3 and the certified human
208 ully applied to different food samples (NIST SRM 2976 mussel tissue, pepper, ginger, wheat flour, red
210 5)Tl/(203)Tl ratio of a sample from the NIST SRM 997 Tl isotope standard in parts per 10(4)) versus 1
211 identical within experimental errors to NIST SRM 2779, demonstrating that Marlin crude is an appropri
212 n a certified reference material, viz., NIST SRM 1640a natural water, which was found to be in good a
214 roposed method was evaluated by analysing of SRM Apple Leaves 1515 certified reference material.
215 y of the method was evaluated by analysis of SRM 1573a with good agreement compared to the certified
216 e method was investigated by the analysis of SRM and the recovery of analytes from various spiked foo
219 er, play major roles in the consolidation of SRM, but these roles are different in each structure vis
224 identify potent and selective inhibitors of SRM, quantitatively ranked the selectivity and potency o
228 of reviews on the fundamental principles of SRM and the remarkable achievements made with these meth
230 irectional hearing, but the possible role of SRM, or whether such specializations exhibit limitations
232 These results demonstrate the utility of SRM-based targeted proteomics to guide the identificatio
235 odified from those utilized for the previous SRM, and all three approaches now incorporate chromatogr
237 rate that the CFF process is able to produce SRMs with uniform size distribution, large oxygen loadin
238 left atrial (LA) wall structural remodeling (SRM) and stratify patients who are likely or not to bene
239 nalysis of fractionated eluates by SRM (SAFE-SRM), to plasma from cancer patients and discovered two
241 rtified Reference Materials (marine sediment SRM 1944, fish tissue 1947, and loamy soil CRM 962-50) a
242 MFP) was not known previously as a selective SRM inhibitor, but has promising characteristics includi
243 caused by the digestion and a less selective SRM transition of the signature peptide as compared to u
247 the correlation between dimethyl-SRM and SID-SRM is within 0.3-33% variation, demonstrating the accur
251 ctive reaction monitoring-mass spectrometry (SRM-MS) is sufficiently sensitive to detect latent HIV r
252 ptimized and finally a sensitive streamlined SRM based analytical method for allergens detection in i
254 w that the lipolytic factor ABHD5 suppresses SRM-dependent spermidine production in TAMs and potentia
255 cally, ABHD5 suppresses spermidine synthase (SRM)-dependent spermidine production in macrophages by i
256 we present can be readily adapted to target SRM in diverse environments and similar strategies could
258 e mice impaired the persistence of long-term SRM but had no effect on sociability and preference for
261 ion before SRM acquisition blocked long-term SRM, supporting the involvement of LTD in the MeA in for
265 is crucial for the persistence of long-term SRM.SIGNIFICANCE STATEMENT Oxytocin receptors (OXTRs) ar
271 on to this trend was the loss of PsbO in the SRM analysis, which highlights the necessity of validati
273 ditions suggests that the performance of the SRM increases when worst-case conditions are replaced by
274 he approach by demonstrating that two of the SRM-identified factors, Mot3 and Azf1, are required for
275 ntermediate precision analyses show that the SRM 1950 profiling is reproducible enough to consider th
276 ng, the results presented here show that the SRM strategy developed for multibiomarker measurement pa
277 tion of a single residue (Ser293) within the SRM is critical for Slimb binding and ubiquitination.
283 holds or improve localization accuracy, thus SRM does not operate in this range of spatial separation
285 The specific contribution of the MeA to SRM formation and the specific actions of oxytocin in th
290 ounds and identified previously unrecognized SRM selective inhibitors and synergistic interactions be
293 th conventional lipidomic quantitation using SRM scans on a triple quadrupole (QqQ) mass analyzer, (2
294 cialization has lowered the barrier to using SRM and the awarding of the Nobel Prize has drawn attent
295 The four materials used in the study were SRM 1648a Urban Particulate Matter, SRM 1649b Urban Dust
296 ion of stable isotope labeling combined with SRM can overcome many of the current potential analytica
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