ライフサイエンスコーパス: SRT

1 SRT and ART produced similar toxicity and survival.

2 SRT are most frequently observed in myopic patients, and

3 SRT was detected as early as 2 h after HCMV infection of

4 SRTs were correlated with both the high-frequency (2-6 k

5 SRTs were measured for 65-dB SPL sentences presented in

6 Of the 35 eligible patients, 22 patients (13 SRT, nine RRT) participated in a battery of tests that i

7 cular abnormalities in 6 control eyes and 29 SRT eyes, of which 18 were attributed to radiation; howe

8 opening/protraction we observe B66 activity, SRT contractions, and spikes in B21 that can be eliminat

9 The earlier, successful adult SRT studies show comparatively good index values implyin

10 n estimate individual patient outcomes after SRT in the modern era.

11 the probability of disease progression after SRT in a multi-institutional cohort of 1,540 patients.

12 Overall treatment response after SRT was 72% (n = 71/99).

13 61% (n = 16/26) had treatment response after SRT.

14 obability of cancer control at 6 years after SRT for PSA-defined recurrence.

15 atal dysfunction can account for the DNM and SRT impairments produced by intralaminar lesions.

16 use were associated with DM, whereas EPE and SRT dose were not.

17 lso suggested dissimilar efficacy of ERT and SRT in correcting pre-existing pathologies in Fabry dise

18 These findings indicate that RSV and SRT do not induce analogous metabolic effects in vivo.

19 Moreover, RSV and SRT treatment elicit differential transcriptional effect

20 ochondrial genes in muscle with both RSV and SRT treatment.

21 of the caloric restriction mimetics RSV and SRT.

22 R, DM, CSM, and OS; androgen suppression and SRT doses > 68 Gy were associated with BcR; and age was

23 standing the mechanisms by which the TAD and SRT of IE62 contribute to the function of this essential

24 GS, EPE, SVI, surgical margins, ADT use, and SRT dose were associated with FFBF.

25 ith adjusted R(2) showed that ONL volume and SRT thickness significantly correlated with Snellen visu

26 trotemporal modulation (STM) sensitivity-and SRTs in noise was examined for 154 HI listeners fitted w

27 tion-only in participants with slow baseline SRTs.

28 variables in the model were PSA level before SRT (P < .001), prostatectomy Gleason grade (P < .001),

29 There was no difference in toxicity between SRT and ART.

30 s the common difference between CRT and both SRT and GNGRT, was associated with higher brain activati

31 n, but the increase in both [Ca2+]SR and [Ca]SRT as frequency increases to 1 Hz is blunted in HF.

32 buffering (by simultaneous [Ca2+]SR and [Ca]SRT measurement) showed no change in HF.

33 arcoplasmic reticulum (SR) Ca2+ content ([Ca]SRT).

34 Diastolic [Ca]SRT changes paralleled [Ca2+]SR, suggesting that SR volu

35 However, it is unknown whether low [Ca]SRT is manifest as reduced: (1) intra-SR free [Ca2+] ([C

36 Thus, reduced [Ca]SRT in HF is associated with comparably reduced [Ca2+]SR

37 [Ca](SRT), as measured by caffeine application, was progressi

38 eased steeply and nonlinearly with both [Ca](SRT) and [Ca](SR).

39 EC coupling can be correlated with both [Ca](SRT) and [Ca](SR).

40 the transient was inferred from I(Ca), [Ca](SRT), [Ca](i), and cellular buffering characteristics.

41 plasmic reticulum (SR) calcium content ([Ca](SRT)) and free SR [Ca] ([Ca](SR)) on the fraction of SR

42 Sarcoplasmic reticulum (SR) Ca content ([Ca](SRT)) in phospholamban knockout mice (PLB-KO) is because

43 ytosolic [Ca] ([Ca](i)) and SR Ca load ([Ca](SRT)) were assessed using fluo-4.

44 tually zero for a small, but measurable [Ca](SRT).

45 increases with [Ca2+]SRT, and for any [Ca2+]SRT is greater in HF versus control.

46 a2+]i and increase total SR Ca2+ load ([Ca2+]SRT) directly indicate the SR Ca2+ leak (before tetracai

47 X in this HF model have more impact on [Ca2+]SRT.

48 Diastolic SR Ca2+ leak increases with [Ca2+]SRT, and for any [Ca2+]SRT is greater in HF versus contr

49 At the same time, SR [Ca2+] ([Ca2+](SRT)) increased 20% (93+/-8 versus 108+/-6 micromol/L).

50 Key factors that determine [Ca2+](SRT) in intact ventricular myocytes include (1) the ther

51 y of the ryanodine receptor at higher [Ca2+](SRT).

52 L cytosol per second at physiological [Ca2+](SRT).

53 data suggest that the leak is steeply [Ca2+](SRT)-dependent, perhaps because of increased [Ca2+]i sen

54 leak) also increased nonlinearly with [Ca2+](SRT) with a steeper increase at higher load.

55 mallest replicator transcript, which we call SRT, and identify a single-sequence element essential to

56 Conclusion SRT outcomes are in part affected by factors associated

57 ients elicited clear delays in contralateral SRT in the paretic hand, whereas TMS applied to PMdIH of

58 plied to M1 led to substantial contralateral SRT delays in both groups.

59 ty-wide rRNA expression signatures at 20-day SRT: anaerobic-oxic-anoxic periods were the primary driv

60 robacter-like NOB, especially for the 40 day SRT sludge.

61 ates the loss of enhanced functions at 5-day SRT operation.

62 AMP decreased SRT-that is, improved inhibition-only in participants wi

63 ndrogen-deprivation therapy before or during SRT (P < .001), and lymph node metastasis (P = .019).

64 Early SRT at low PSA levels after RP is associated with improv

65 ividual gene loops by gene mutation enhances SRT synthesis.

66 stream catchments; (b) operation at extended SRT may enhance antibiotic removal, as shown for sulfame

67 hospitalized with acute respiratory failure, SRT compared with usual care did not decrease hospital L

68 10), 90% for PED (kappa = 0.78), and 79% for SRT (kappa = 0.53).

69 0.05 and 1.0 ng/mL, considered eligible for SRT at the time of PSMA.

70 D, and to identify possible risk factors for SRT.

71 n element differentiating CRT and GNGRT from SRT, was associated with higher brain activation in the

72 Patients were stratified by treatment group (SRT v RRT) and into younger (Y) and older (O) groups by

73 Both the 16-Gy and 24-Gy SRT arms received significantly fewer ranibizumab treatm

74 H-SRT was well tolerated and resulted in a median survival

75 a median survival time of 11 months after H-SRT, independent of re-operation or concomitant chemothe

76 Variables included age, surgery before H-SRT, time to first recurrence, reirradiation dose, inclu

77 sponse and should not be disqualified from H-SRT.

78 sociated with improvement in survival from H-SRT.

79 rmine the efficacy and toxicity profile of H-SRT alone or in addition to repeat craniotomy or concomi

80 o examine the efficacy and tolerability of H-SRT in recurrent HGG.

81 actionated stereotactic radiation therapy (H-SRT).

82 ients with recurrent HGG were treated with H-SRT (median dose, 35 Gy in 3.5-Gy fractions).

83 ation dose, inclusion of chemotherapy with H-SRT, and gross tumor volume (GTV).

84 cate differential expression of rRNA at high SRTs, which may further explain why high SRTs promote hi

85 igh SRTs, which may further explain why high SRTs promote higher rates of micropollutant biotransform

86 at model that closely approximated the human SRT, using intracranial self-stimulation to promote rapi

87 The interaction of the IE62 SRT with nucleolar-ribosomal protein EAP resulted in the

88 Although there was no significant change in SRT, BOLD activation was reduced in right cerebellum and

89 d poorly predicted accompanying increases in SRT.

90 er(s) best explains concomitant increases in SRT.

91 Initial bilateral facilitation occurred in SRT trials with slow RT.

92 ify plausible mechanisms for correlations in SRTs and RRTs.

93 gorithm was found to provide improvements in SRTs on the order of 6.5 to 11.0 dB across listening con

94 Subsequent management, including SRT, and most recent PSA were recorded using medical rec

95 EtOH increased SRTs-that is, impaired inhibition-at doses that did not

96 by a motor neuron (B66) and that B66-induced SRT contractions trigger centripetal spikes in B21.

97 is study examines the value of PSMA-informed SRT in improving treatment outcomes in the context of bi

98 Instead, SRT increases best correlated with delays in the onset o

99 The impact of dose-intensified SRT on QoL was minor, except for a significantly greater

100 Dose-intensified SRT was associated with low rates of acute grade 2 and 3

101 received standard-dose cranial irradiation (SRT) of 36 Gy would have a lower performance on standard

102 (RNA) analysis localized the 0.2- to 0.25-kb SRT to an apparently noncoding segment near the center o

103 For the left SRT, significant facilitation occurred on the right afte

104 Additionally, mean SRT decreased with decreasing SOA, revealing facilitatio

105 d no effect on SRT accumulation; however, no SRT was detected in RNA preparations from cycloheximide-

106 ing order: Y/SRT less than Y/RRT less than O/SRT less than O/RRT.

107 A single dose of SRT significantly reduces intravitreal injections over 2

108 A single dose of SRT significantly reduces ranibizumab retreatment for pa

109 Surprisingly, the beneficial effects of SRT on glucose homeostasis and of both compounds on ener

110 13), and 7 patients (31.8%) had a history of SRT or retinal detachment in the fellow eye (p = 0.13).

111 atectomy PSA levels that delay initiation of SRT.

112 Collectively, the location of SRT near the center of the oriLyt core region, its early

113 , we present the first mathematical model of SRT in a 3D lung structure to provide insight into answe

114 omogram we developed predicts the outcome of SRT and should prove valuable for medical decision makin

115 ding justifies a randomized imaging trial of SRT with or without (68)Ga-PSMA-11 PET/CT investigating

116 assays, the sequence immediately upstream of SRT functioned as a promoter responsive to HCMV infectio

117 ease the internal and ecological validity of SRT experiments and, ultimately, SRT's external validity

118 potential impact of (68)Ga-PSMA-11 PET/CT on SRT.

119 ibitor phosphonoformic acid had no effect on SRT accumulation; however, no SRT was detected in RNA pr

120 )Ga-PSMA-11 PET/CT implied a major impact on SRT planning in 52 of 270 patients (19%) with PCa early

121 At an optimal SRT between 0.5 and 1.3 days and tc of 15 min and ts of

122 ther metabolic tissues in response to RSV or SRT treatment.

123 d then randomly assigned to arm A (BCNU plus SRT), arm B (BCNU plus ART), arm C (cisplatin plus BCNU

124 U plus ART), arm C (cisplatin plus BCNU plus SRT), or arm D (cisplatin plus BCNU plus ART).

125 Pre-SRT PSA, GS, SVI, surgical margins, and ADT use were ass

126 Using a pre-SRT PSA cutoff </= 0.5 versus > 0.5 ng/mL, 5-year and 10

127 te was 56% overall, 71% for those with a pre-SRT PSA level of 0.01 to 0.2 ng/mL (n = 441), 63% for th

128 On multivariable analysis, pre-SRT PSA, GS, EPE, SVI, surgical margins, ADT use, and SR

129 thologic tumor stage, Gleason score, and pre-SRT PSA were associated with BcR, DM, CSM, and OS; andro

130 Each pre-SRT PSA doubling increased significantly the relative ri

131 The median pre-SRT PSA was 0.5 ng/mL (interquartile range, 0.3 to 1.1).

132 sensitivity was most critical in predicting SRTs for listeners < 65 years old or with HFA <53 dB HL.

133 prostate cancer (PCa) salvage radiotherapy (SRT) after radical prostatectomy are usually drawn in th

134 mogram of outcomes for salvage radiotherapy (SRT) following radical prostatectomy (RP) for prostate c

135 o describe outcomes of salvage radiotherapy (SRT) for men with detectable prostate-specific antigen (

136 This new rat SRT model clarifies the basal ganglia-limbic system dich

137 In total, 99 of 146 received SRT with a median follow-up after radiation treatment of

138 d Methods A total of 1,106 patients received SRT between January 1987 and July 2013, with median foll

139 ear survival rates for patients who received SRT (arms A and C) compared with ART (arms B and D) were

140 In men with a negative PSMA who received SRT, 85% (n = 23/27) demonstrated a treatment response,

141 In the Fabry mice receiving SRT but not ERT, BH4 deficiency was restored, concomitan

142 lthough stochastic accumulator models relate SRT increases to reduced rates of accumulation or increa

143 ffect target volume delineations for routine SRT.

144 is equivalent to survival using standard RT (SRT).

145 (RT) needed to inhibit a response (Stop RT [SRT]), relative to the time taken to execute a simple re

146 that progressed to a further retinal tear/s (SRT) during follow-up.

147 ticipants received 16 Gray, 24 Gray, or sham SRT.

148 d right and left thumb extensions in simple (SRT), choice (CRT) and go/no-go auditory RT paradigms.

149 e describe thermoplastic processing of squid SRT via hot extrusion of fibres, demonstrating the poten

150 Resveratrol (RSV) and SRT1720 (SRT) elicit beneficial metabolic effects and are postula

151 In summary, the splicing-based RNA tagging (SRT) method provides a convenient and robust tool to pro

152 The serial reaction time task (SRT) is a sequence learning example of human nondeclarat

153 the prevalence of subsequent retinal tears (SRT) in patients with a PVD, and to identify possible ri

154 The robust sucker ring teeth (SRT) from squid and cuttlefish are one notable exception

155 n other systems suggest the possibility that SRT plays a role in initiating or regulating HCMV lytic-

156 responsible for this behaviour and show that SRT consist of semi-crystalline polymers, whereby heat-r

157 RNA ligase-mediated 3'-RACE showed that SRT is not polyadenylated and has heterogeneous 3' ends

158 upstream of a reporter gene, suggesting that SRT is the product of a discrete transcription unit.

159 The SRT is believed to be impaired by basal ganglia, not lim

160 The SRT of IE62 interacted with the nucleolar-ribosomal prot

161 pital LOS was 10 days (IQR, 6 to 17) for the SRT group and 10 days (IQR, 7 to 16) for the usual care

162 For the SRT group, the median (interquartile range [IQR]) days o

163 tamen increased choice response time for the SRT task.

164 , STM sensitivity significantly improved the SRT prediction (DeltaR(2 )= .13; total R(2 )= .44).

165 There were higher scores at 6 months in the SRT group for the SPPB score (difference, 1.1 [95% CI, 0

166 Patients in the SRT group received daily therapy until hospital discharg

167 assays showed that the VZV IE62 lacking the SRT trans-activated the early VZV ORF61 promoter at only

168 mbic system pathology does in fact leave the SRT unimpaired.

169 fore behavioral training, performance of the SRT task concurrently with the secondary task elicited a

170 Here, we developed a rodent model of the SRT task to examine the specific roles of the hippocampa

171 g, subjects had automated performance of the SRT task.

172 When the serine and acidic residues of the SRT were replaced with Ala, Leu, and Gly, trans-activati

173 Subjects performed the SRT task during two functional magnetic imaging sessions

174 These results suggest that the SRT plays an important role in VZV viral gene expression

175 nder the self-paced condition than under the SRT condition.

176 When the SRT of IE62 was replaced with the SRT of equine herpesvi

177 When the SRT of IE62 was replaced with the SRT of equine herpesvirus 1 (EHV-1) IEP, its trans-activ

178 icating that the IE62 TAD functions with the SRT of HSV-1 ICP4 to trans-activate viral promoters.

179 orm the eye-hand SOA task and analyzed their SRTs and RRTs.

180 -mechanically based statistical rate theory (SRT) expression for the evaporation flux and applying a

181 the generality of strong reciprocity theory (SRT) is limited by the existence of anonymous spontaneou

182 Salvage radiation therapy (SRT) may eradicate locally recurrent cancer, but studies

183 dose-intensified salvage radiation therapy (SRT) of the prostate bed.

184 mediated ERT or substrate reduction therapy (SRT) for 6 months.

185 Surfactant replacement therapy (SRT) involves instillation of a liquid-surfactant mixtur

186 the variance in speech-reception thresholds (SRTs) for hearing-impaired (HI) listeners fitted with in

187 Speech reception thresholds (SRTs) were measured using a Coordinate Response Measure

188 entified severe refractory thrombocytopenia (SRT) early in life as a major risk factor for poor outco

189 ents under self-paced, simple reaction time (SRT) and choice reaction conditions (CRT).

190 ls in the setting of a simple reaction time (SRT) paradigm performed with the hand contralateral to t

191 testing subjects in a serial reaction time (SRT) task under both single-task and dual-task condition

192 pendently manipulated: simple reaction time (SRT) task, go/no-go reaction time (GNGRT) task, and choi

193 during acquisition of serial reaction time (SRT) tasks.

194 elating variations in saccade reaction time (SRT) to variations in such parameters as baseline, rate

195 memory, and self-paced serial reaction time (SRT), a measure of intentional response speed.

196 s-finger tapping (FT), simple reaction time (SRT), and four-choice reaction time (4CRT)-twice during

197 omitant increases in saccadic reaction time (SRT).

198 A version of the serial response time (SRT) task was developed, in which the locations of targe

199 (MLSS) concentrations, solid retention time (SRT) and dissolved oxygen (DO) concentrations), two full

200 th (40-50 days) and a solids retention time (SRT) that allows establishment of L-GLDA degraders (>15

201 es and analogues, (ii) solid retention time (SRT), (iii) fractions sorbed onto solids, and (iv) dynam

202 D typically results in loss of VA over time, SRT is associated with relatively well-preserved VA over

203 perated at different solids residence times (SRT) or feeding frequencies.

204 5 degrees C at short solids retention times (SRT; 0.24-2.8 days), hydraulic contact times (tc; 8 and

205 eye-hand movements, saccade reaction times (SRTs) and reach reaction times (RRTs) are correlated in

206 s with 10 and 40 day solids retention times (SRTs), complete nitrification was accomplished after a l

207 s per day and at two solids retention times (SRTs).

208 e bioreactor) at two solids retention times (SRTs): 20 and 5 days.

209 sue innervated by B21, the subradula tissue (SRT), is innervated by a motor neuron (B66) and that B66

210 , subretinal fluid (SRF), subretinal tissue (SRT), and pigment epithelial detachments (PEDs) at week

211 bretinal fluid (SRF), and subretinal tissue (SRT).

212 ial detachment [PED], and subretinal tissue [SRT]).

213 ng mechanical ventilation were randomized to SRT (n=150) or usual care (n=150) from October 2009 thro

214 fossa on PSMA, 81% (n = 29/36) responded to SRT.

215 tifies men into a high treatment response to SRT (negative or fossa-confined PSMA) versus men with po

216 fined PSMA) versus men with poor response to SRT (nodes or distant-disease PSMA).

217 endently predictive of treatment response to SRT and stratifies men into a high treatment response to

218 ostatectomy have a long-term PSA response to SRT when treatment is administered at the earliest sign

219 clinical variables and treatment response to SRT.

220 e median (7.4 mm(3)) were more responsive to SRT, with 3.9 PRN injections versus 7.1 in comparable sh

221 Total SRT volume was reduced by an average of 0.07 mm(3) at mo

222 Our data show that the serine-rich tract (SRT) of VZV IE62, which is well conserved within the alp

223 ctivation domain (TAD), a serine-rich tract (SRT), and binding domains for USF, TFIIB, and TATA box b

224 s the previously identified early transcript SRT, two adjacent but nonoverlapping, roughly 200-bp del

225 referred to as Ssu72-restricted transcripts (SRTs).

226 ll benefit from salvage radiation treatment (SRT).

227 These two SRTs were used to influence the rates of micropollutant

228 validity of SRT experiments and, ultimately, SRT's external validity.

229 condition, actual RTs were longer than under SRT, but APAs were more similar to those under self-pace

230 ) of patients with a negative PSMA underwent SRT whereas 55% (33/60) did not.

231 ings but may be positively affected by using SRT at lower PSA levels, including reductions in BcR, DM

232 terize the clinical features associated with SRT formation against those eyes with non-subsequent ret

233 95% CI, 40% to 56%) of patients treated with SRT alone at PSA levels of 0.50 ng/mL or lower were dise

234 prostate-specific antigen (PSA) treated with SRT with or without concurrent androgen-deprivation ther

235 ologic test scores in the following order: Y/SRT less than Y/RRT less than O/SRT less than O/RRT.