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1 SUV cannot be used to quantify (18)F-fluoromethylcholine
2 SUV corrected for lean body mass (SUL and SULpeak) were
3 SUV is, however, associated with multiple sources of var
4 SUV measurements and rate of glucose uptake values were
5 SUV quantification of (18)F-FLT uptake in glioma had an
6 SUV quantification shows notable differences between (18
7 SUV ratios (affected disk/reference disk) were determine
8 SUV ratios (SUVRs) are used for relative quantification
9 SUV ratios (SUVRs) showed a strong correlation in tracer
10 SUV ratios and GM volumes were compared using regional a
11 SUV(max) was not related to plasma VEGF-A at all scan mo
12 SUVs and target-to-background ratios for the symptomatic
13 SUVs and the number of medullar lesions detected by (64)
14 SUVs at 60 min after tracer injection also correlated (r
15 SUVs for any RR were not significantly different over ti
16 SUVs from 60 to 120 min after injection derived from eac
17 at 6 mo (P = 0.014) and 12 mo (P = 0.0005); SUV maximal percentage change from baseline and clinical
18 6 mo (P = 0.0147) and 6-12 mo (P = 0.0053); SUV change at 6 mo and overall survival (P = 0.018); num
19 with regards to AC-CTref: for (18)F-FET (A)-SUVs as well as volumes of interest (VOIs) defined by a
20 positive/ HER2-negative cancers and absolute SUV(max) after two cycles of chemotherapy for HER2-posit
24 s 2.18 (IQR 2.00-2.65), and all cases had an SUV(max) greater than 1.6 (the threshold for defining ca
25 robe PET/CT imaging of HCC70 tumors shows an SUV of 0.32 +/- 0.03 for vehicle-, 0.50 +/- 0.01 for GDC
26 e PET/CT imaging of MDAMB468 tumors shows an SUV of 0.35 +/- 0.02 for vehicle- and 0.73 +/- 0.05 for
28 old had no significant influence, whereas an SUV threshold of 2.5 proved optimal for automated lesion
33 s a strong correlation in size (r= 0.98) and SUV (r= 0.91) and a moderate correlation in contrast (rh
34 -to-blood-pool SUV ratio was 59% higher, and SUV gradient was 51% higher, with good correlation betwe
36 h compartmental modeling parametric maps and SUV segmentations using simulations of clinically releva
38 n adaptive template registration method, and SUV ratio 3D-SSP values were computed using the pons and
39 expressing neuroendocrine tumors (NETs), and SUV measurements are suggested for treatment monitoring.
40 onal T1-weighted volumetric MR sequence, and SUV estimations were compared with CT AC for whole-image
42 binding potential ([Formula: see text]) and SUV ratio ([Formula: see text]) images were compared.
43 account for differences in lesion volume and SUV quantification between reconstruction algorithms.
44 sible tumor uptake of (68)Ga-NOTA-AE105, and SUVs were obtained from tumor lesions by manually drawin
49 retest studies have been performed to assess SUV repeatability, although a comparison of reports is c
50 VpeakW) was compared with that of an average SUV computed from the 40 hottest voxels, irrespective of
52 lue within a lesion (SUVmax) and the average SUV within a small volume of interest around the site of
53 to-background ratios; for (68)Ga-DOTANOC (B)-SUVs as well as VOIs defined by a 50% threshold for all
58 Across patients, the correlation between SUV and apparent diffusion coefficient was weak and nons
61 erature suggests that the difference between SUVs measured before and after treatment can be used to
63 ically low intrasubject variability in blood SUV and uptake time and the accordingly small deltaCF va
64 SUR compared with TRVSUVVariability in blood SUV and uptake time has been identified as a causal fact
65 antial for the level of variability in blood SUV and uptake time typically observed in the clinical c
66 computed as the ratio of tumor SUV to blood SUV and were uptake time-corrected to 75 min after injec
70 In order to determine the mean normal bone SUV, initially a 1-cm spheric volume of interest (VOI) w
73 se association was found between whole-brain SUV and reported cigarettes per day (P<0.05), but no sig
74 sed bone compartment reduced the whole-brain SUV estimation bias of Dixon-based PET/MR AC by 95% comp
75 CC values were higher for VTs than for brain SUVs, which were both moderate to high; however, lower I
76 kers and non-smokers differed in whole-brain SUVs (P=0.006) owing to smokers having 16.8% lower value
77 r uptake of [(18)F]6b in the olfactory bulb (SUV of 0.34 at 30 min pi) accompanied by a low uptake in
78 ulation in renal allografts as determined by SUVs on PET and diffusion restriction as determined by a
79 of interest were extracted and quantified by SUVs and by 2-tissue-compartment modeling for calculatio
81 No significant differences in cerebellar SUVs were found among cases with different amounts or ty
85 From the PET data, regional and composite SUV ratios (SUVRs) with and without PVEC were obtained.
87 -05270430 was fast, with peak concentration (SUVs of 1.5-1.8 in rhesus monkeys) achieved within 7 min
91 The key secondary objective was to correlate SUV with the proliferation marker Ki-67 at baseline and
93 variable (SUV; 14.5 vs 11.2; P = .05), delta SUV (10.3 vs 5.4; P = .02), and relative delta SUV (0.6
94 V (10.3 vs 5.4; P = .02), and relative delta SUV (0.6 vs 0.4; P = .02) were significantly higher in t
95 emoradiotherapy that demonstrates that delta SUV of less than 45% is associated with patients with re
96 analyses, the initial mean SUV, Deltamaximum SUV, and Deltatumor-to-background ratio demonstrated the
97 e the repeatability of (18)F-NaF PET-derived SUV imaging metrics in individual bone lesions from pati
98 significant differences in (18)F-FDG-derived SUVs were observed between different grades (P = 0.38).
101 ility and growth using DMPC-NP-SLBs and DMPC-SUVs, with and without BaP, as their sole carbon source.
102 cles (SUVs) or DMPC-NP-SLBs with excess DMPC-SUVs to support colloidal stability, when added to satur
103 d in 20 lung cancer lesions yielded for each SUV metric its mean value, relative measurement error, a
105 using SUVpeak Although changes in (18)F-FLT SUV after treatment cannot be directly interpreted as a
106 ificant associations included the following: SUV and prostate-specific antigen percentage change at 6
107 f SUVmax, the repeatability coefficients for SUV, SUVAUC, and SUVTBR were 26% (ICC, 0.95), 31% (ICC,
108 rmined using the Pearson coefficient (r) for SUV and size and the Spearman rank coefficient (rho) for
109 igorous protocol compliance, but in general, SUV is a highly repeatable imaging biomarker that is ide
111 er a proprietary software tool can harmonize SUV estimation sufficiently to provide consistent respon
113 F-FIMX uptake into the human brain was high (SUV = 4-6 in the cerebellum), peaked at about 10 min, an
116 of the needle to the focus with the highest SUV, as well as the mean difference between the maximum
117 aft function in one subject, whereas hotspot SUV was unchanged in subjects with stable graft function
118 ceptable SUV variability, the lowest bias in SUV was observed using an 8-min acquisition per bed posi
119 PERCIST suggest a threshold of 30% change in SUV to define partial response and progressive disease.
120 re better correlated with PCR than change in SUV(max) (AUC, 0.78; P = .11) or change in TLG (AUC, 0.6
121 ologic response vary by phenotype: change in SUV(max) or TLG are most adequate for TNBCs and ER-posit
122 e number of malignant lesions and changes in SUV on follow-up Na(18)F PET/CT significantly correlate
123 ting for the absence of group differences in SUV and distribution volume (VT) estimated with an arter
125 ess than 1.5 cm showed a greater increase in SUV from GeminiTF to DigitalTF than those lesions 1.5 cm
127 ative methods including percentage change in SUVs, lean body mass-corrected (SUL) SULpeak, SULmax, an
131 Baseline PET imaging parameters, including SUV, proliferative volume, or metabolic tumor volume, di
132 h PET/MRI examinations, lead to inconsistent SUV measurements in serial studies, which may affect the
134 int-spread function (PSF) modeling increases SUVs significantly in tumors but only moderately in the
135 uantifying heterogeneity, image intensities (SUVs) are typically resampled into a reduced number of d
136 , simplified methods were evaluated-that is, SUVs and tumor-to-blood ratios (TBR)-for several scan in
139 s thoracic organ motion and increases lesion SUV, detectability, and delineation, thus potentially af
140 sponse assessment, the reliability of lesion SUVs, notably their test-retest stability, thus becomes
141 Lesion quantity, mean and maximum lesional SUV, z score, and percentage of affected bone volume are
144 atients with furosemide presented with lower SUV and radioactivity concentration within the urinary b
149 d for 18 organs in all patients, and maximum SUV and mean SUV were recorded for all the identified ma
150 The association of risk factors and maximum SUV of (64)Cu-DOTATATE was found driven by body mass ind
154 ss than 5%; 28 parameters, including maximum SUV, showed variation with a COV in the range of 5%-10%.
155 2 representative lesions, the lesion maximum SUV was 36% higher with DigitalTF than with GeminiTF, le
159 l as the mean difference between the maximum SUV in the whole lesion and at the needle tip, was calcu
161 ns in all patients, and maximum SUV and mean SUV were recorded for all the identified malignant lesio
164 ng-characteristic analyses, the initial mean SUV, Deltamaximum SUV, and Deltatumor-to-background rati
166 better predictive value for percentage mean SUV (P = 0.02) and similar prediction for peak SUV (P =
168 ivity level, and errors in the reported mean SUV ranged from -1.6% to 100% for a region with controll
171 tumor lesions in 22 patients, with a median SUV(max) (maximum standardized uptake value) of 6.9 (ran
173 calculated as the percentage mean myocardial SUV change between 0 and 5 min and 15 and 20 min after r
175 nalyses were conducted for the assessment of SUV variations between PETA and PETBImage artifacts were
177 orrection for uptake time the correlation of SUV measures and TLG between the 60- and 90-min data sig
183 with background uptake, the average bias of SUVs in background volumes of interest was 2.4% +/- 2.5%
184 pituitary gland; and for (18)F-FDG (C)-RD of SUVs of the whole brain and 10 anatomic regions segmente
185 elf at 40 min, resulting in several types of SUVs: SUV, SUVAUC, and SUVTBR The test-retest repeatabil
186 R2-positive phenotype, absolute SUV(max) (or SUV(peak)) values at PET imaging after two cycles of che
187 t group differences in pseudoreference VT or SUV, excepting whole-brain VT, which was higher in cLBP
191 tative (18)F-fluoromethylcholine parameters (SUV, MTV, and total uptake in the lesion) were approxima
194 a change of >/=30% decrease in (18)F-FDG PET SUV given a true decrease of 40%) and specificity (proba
196 lTF than with GeminiTF, lesion-to-blood-pool SUV ratio was 59% higher, and SUV gradient was 51% highe
197 4 h after injection, but tumor-to-blood-pool SUV ratios increased with time after injection (P = 0.04
198 at motile bacteria could successfully propel SUVs and LUVs with a velocity of 28 mum s(-1) and 13 mum
202 correction (AC), and inaccurate radiotracer SUV estimation can limit future PET/MR clinical applicat
203 %CI, 0.97-0.99; Delta = 0.44), and reference SUV (spleen: ICC, 0.81; Delta = 1.10; liver: ICC, 0.79;
206 5.6% and 6.6%, respectively, and scan-rescan SUV variations were within +/-20% in 95% of the cases.
211 n distribution volume ratio (DVR) and static SUV ratio (SUVR) using the cerebellum as a reference tis
212 of the studies are analyzed using the static SUV ratio (SUVR) approach because of its simplicity.
215 40 min, resulting in several types of SUVs: SUV, SUVAUC, and SUVTBR The test-retest repeatability of
216 t level that, after docking of the templated-SUVs to supported lipid bilayers (SBL), one to two pairs
217 igation of simplified approaches showed that SUV curves normalized to patient weight, and injected tr
225 thods were evaluated: (1) R(D), dividing the SUV range into D equally spaced bins, where the intensit
227 The clinical data showed an increase in the SUV estimates for SFS-RR images up to 34% for peak SUV a
229 ng parameters were assessed by measuring the SUV and coefficient of variation in different regions (a
230 subjects with elevated 95% percentile of the SUV (SUV95) were more likely to develop symptomatic RP (
231 reflect treatment effects than those of the SUV, and accordingly there is a need to compute parametr
232 35), which was significantly higher than the SUV, 2.7 (interquartile range, 1.6-3.8), of the thyroid
233 t was a standardized static uptake time (the SUV from 60 to 65 min was selected for all scans), the s
234 The best repeatability was found using the SUV metrics of the averaged PERCIST target lesions (repe
235 y, precentral gyrus) was normalized with the SUV from candidate pseudoreference regions (i.e., occipi
244 LINDE to blood cells and peripheral tissues, SUV is not a sufficient surrogate of VT from 2-tissue-co
250 erferon-alpha induced a mean change in tumor SUV(max) of -47.0% (range, -84.7 to +20.0%; P < 0.0001)
252 SURs were computed as the ratio of tumor SUV to blood SUV and were uptake time-corrected to 75 mi
253 ed with careful attention to protocol, tumor SUV has a within-subject coefficient of variation of app
262 nkey revealed moderate initial brain uptake (SUV, 1.9 at 1 min after injection) with a rapid washout.
263 rats revealed moderate initial brain uptake (SUV, approximately 1.5 at 1 min after injection) and rap
264 ll measures of carotid artery/plaque uptake (SUV) and greater than 0.6 in almost all measures of targ
265 mors showed focal (89)Zr-bevacizumab uptake (SUVs at 144 h after injection were 1.0-6.7), whereas no
266 iple sources of variability, and to best use SUV for response assessment, an understanding of the rep
267 FDG uptake and diffusion were measured using SUV and apparent diffusion coefficient, and correlation
268 5-point score) or semiquantitatively (using SUV and DeltaSUV) predicted both PFS and OS (P < 0.01 fo
270 ruction using the standardized uptake value (SUV) and the metabolic volume as metrics for quantificat
272 miscalculation of standardized uptake value (SUV) in PET images can be caused by inappropriate attenu
273 Change in hotspot standardized uptake value (SUV) predicted loss of graft function in one subject, wh
274 24-mo florbetapir standardized uptake value (SUV) ratio (SUVR) changes; to relate those changes to 24
277 (6 x 5 cm with a standardized uptake value [SUV] of 14), a 1.3-cm subcutaneous nodule in the left th
278 form of maximum standardized uptake values (SUV(max)) and uptake volumes before and after treatment
280 re obtained, and standardized uptake values (SUV) were calculated for major organs including brain, h
284 early change in standardized uptake values (SUVs) of 3'deoxy-3'-(18)F-fluorothymidine ((18)F-FLT) us
286 Whole-brain standardized uptake values (SUVs) were determined, and analysis of variance was perf
288 The mean prestandardized uptake variable (SUV; 14.5 vs 11.2; P = .05), delta SUV (10.3 vs 5.4; P =
290 L-serine] (DOPS) small unilamellar vesicles (SUVs) dramatically enhances the aggregation rate of alph
291 C in the form of small unilamellar vesicles (SUVs) or DMPC-NP-SLBs with excess DMPC-SUVs to support c
293 The most common reasons for failure were SUV outside specifications, incomplete submission, and u
294 ion, we have established ranges beyond which SUV differences are likely due to legitimate biologic ef
295 arameters derived from kinetic analysis with SUV ratio (SUVR) calculated over different imaging time
296 There was a significant association with SUV(max) and C-reactive protein (r=0.58, p=0.04) and qua
299 tatic scans as the percentage of voxels with SUVs more than 3 SDs from the mean values obtained for s
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