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1 ion of the somatostatin analogue octreotide (Sandostatin).
2 e essential secondary structural features of sandostatin.
3 analog has a 2.4 times longer half-life than sandostatin.
4 rat SSTR5 compared to somatostatin[1-14] and sandostatin.
5 mes weaker binding affinity for mSSTR2b than sandostatin.
6 d6 and for other highly bioactive analogs of sandostatin.
7 rSSTR5 receptor selectivities as compared to sandostatin.
8 inhibition of growth hormone secretion than sandostatin.
9 (2)) related to somatostatin analogues (e.g. sandostatin) acting at somatostatin receptors, CTAP whic
10 of beta-VI turns and can be incorporated in sandostatin analogs maintaining the essential secondary
11 statin-like and opioid-like bioactivities of sandostatin analogs, the present investigation shows the
13 proposed structures for the design of novel sandostatin-based conformationally restricted peptidomim
16 y diffraction investigations which show that sandostatin can adopt both the beta-sheet and the 3(10)
17 lic stability of lanthionine-sandostatin and sandostatin have been studied in rat brain homogenates.
19 2 mo, and the mean time gap between the last Sandostatin LAR injection and the second (68)Ga-DOTATATE
22 rmational analysis of a series of analogs of sandostatin (octreotide, D-Phe1-c[Cys2-Phe3-D-Trp4-Lys5-
23 ys7+ ++-Thr8-ol (disulfide bridged) known as sandostatin (or SMS 201-995 or octreotide) with both som
26 hesis of the thioether bridged analog (1) of sandostatin (SMS 201,995) and several lanthionine hexa-,
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