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1 ion of the somatostatin analogue octreotide (Sandostatin).
2 e essential secondary structural features of sandostatin.
3 analog has a 2.4 times longer half-life than sandostatin.
4 rat SSTR5 compared to somatostatin[1-14] and sandostatin.
5 mes weaker binding affinity for mSSTR2b than sandostatin.
6 d6 and for other highly bioactive analogs of sandostatin.
7 rSSTR5 receptor selectivities as compared to sandostatin.
8  inhibition of growth hormone secretion than sandostatin.
9 (2)) related to somatostatin analogues (e.g. sandostatin) acting at somatostatin receptors, CTAP whic
10  of beta-VI turns and can be incorporated in sandostatin analogs maintaining the essential secondary
11 statin-like and opioid-like bioactivities of sandostatin analogs, the present investigation shows the
12       The metabolic stability of lanthionine-sandostatin and sandostatin have been studied in rat bra
13  proposed structures for the design of novel sandostatin-based conformationally restricted peptidomim
14 ected to refine the pharmacophore models for sandostatin bioactivities.
15               The structural modification of sandostatin by introducing a lanthionine bridge resulted
16 y diffraction investigations which show that sandostatin can adopt both the beta-sheet and the 3(10)
17 lic stability of lanthionine-sandostatin and sandostatin have been studied in rat brain homogenates.
18  bone, lung, or lymph nodes before and after Sandostatin LAR administration (P > 0.05).
19 2 mo, and the mean time gap between the last Sandostatin LAR injection and the second (68)Ga-DOTATATE
20 receiving long-acting repeatable octreotide (Sandostatin LAR) were included in the study.
21  values measured after the administration of Sandostatin LAR.
22 rmational analysis of a series of analogs of sandostatin (octreotide, D-Phe1-c[Cys2-Phe3-D-Trp4-Lys5-
23 ys7+ ++-Thr8-ol (disulfide bridged) known as sandostatin (or SMS 201-995 or octreotide) with both som
24   These results facilitate the design of new sandostatin peptidomimetics.
25                This is the initial report on sandostatin showing that attempts to explain all NMR dat
26 hesis of the thioether bridged analog (1) of sandostatin (SMS 201,995) and several lanthionine hexa-,

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