ライフサイエンスコーパス: Schaffer

1 Schaffer collateral axons form excitatory synapses that

2 Schaffer collateral synapses on CA2 neurons are distinct

3 Schaffer collateral-CA1 tetanic long-term potentiation d

4 Schaffer-collateral long-term potentiation (LTP) was imp

5 y ramifying in the pyramidal cell layer; (2) Schaffer collateral/commissural pathway-associated inter

6 whenever tested (n = 5; 1 basket cell and 4 Schaffer-associated interneurons), were abolished by the

7 we measure this replenishment rate at active Schaffer collateral terminals by determining the maximum

8 ed transcripts in rat hippocampus 3 hr after Schaffer-CA1 LTP induction in vivo, we identified a neur

9 voltage and calcium signals in spines after Schaffer collateral synapse stimulation.

10 ium to block synaptic transmission, allowing Schaffer-collateral axon fiber volleys to be recorded fr

11 path-dentate gyrus granule cell, CA3-CA3 and Schaffer collateral-CA1 synapses without effects at moss

12 of anterior piriform (olfactory) cortex, and Schaffer-commissural synapses were studied in slices of

13 d activation of entorhinal cortical (EC) and Schaffer collateral (SC) inputs to hippocampal CA1 pyram

14 Maynard Smith's infinite population ESS and Schaffer's finite population ESS.

15 imulation in the hippocampal mossy fiber and Schaffer collateral pathways.

16 e dendrites were unlabeled, mossy fibers and Schaffer collaterals in the hippocampal formation, baske

17 l CA1 neurons through the perforant path and Schaffer collateral synapses, respectively.

18 n excitatory inputs, the perforant path, and Schaffer collaterals during theta and non-theta behavior

19 at the CA3 recurrent collateral synapses and Schaffer collateral-CA1 synapses, but not at the mossy f

20 terneuron, the so-called 'basket cells' and 'Schaffer collateral-associated' cells, which innervate s

21 At Schaffer collateral synapses, the induction of long-term

22 At Schaffer collateral-CA1 synapses in the hippocampus, pre

23 (AMPA)-type glutamate receptors (AMPARs) at Schaffer collateral to CA1 synapses in postischemic hipp

24 nylglycine (DHPG) was markedly attenuated at Schaffer collateral-CA1 synapses of mice lacking caveoli

25 This occurred both at Schaffer collateral-CA1 synapses and at CA3-CA3 synapses

26 ficits and specific synaptic dysfunctions at Schaffer collateral to CA1 synapses.

27 NMDA receptor-dependent LTP was enhanced at Schaffer collateral-CA1 pyramidal cell synapses.

28 s of both AMPAR and NMDAR currents evoked at Schaffer collateral synapses.

29 Although CB1Rs are also expressed at Schaffer-collateral excitatory terminals, long-term plas

30 e of cleft glutamate concentrations found at Schaffer collateral synapses.

31 ly disrupted, revealing hyperexcitability at Schaffer collateral-CA1 synapses and depression of mossy

32 nd chemically induced NMDAR-dependent LTD at Schaffer collateral synapses but did not affect potentia

33 stores each prevent the induction of LTD at Schaffer collateral-CA1 synapses.

34 GluR-dependent long-term depression (LTD) at Schaffer collateral to CA1 pyramidal synapses of the hip

35 erm depression of synaptic strength (LTD) at Schaffer collateral-CA1, commissural/associational-CA3 a

36 lectively required for those forms of LTP at Schaffer collateral synapses that recruit a presynaptic

37 LTP at Schaffer collateral-CA1 pyramidal cell synapses remained

38 show normal synaptic transmission and LTP at Schaffer collateral-CA1 synapses, and have no deficits i

39 idylinositol 3-kinase (PI3-kinase) in LTP at Schaffer collateral/commissural fiber-CA1 synapses in ra

40 aCaMKII is essential for induction of LTP at Schaffer commissural-CA1 synapses in vivo, but is not re

41 equent threshold for the induction of LTP at Schaffer-commissural synapses through a reduction in the

42 mpal slices, long-term potentiation (LTP) at Schaffer collateral fiber synapses onto CA1 pyramidal ce

43 to modulate long-term potentiation (LTP) at Schaffer collateral-CA1 hippocampal synapses.

44 we show that long-term potentiation (LTP) at Schaffer collateral-CA1 synapses is greatly enhanced in

45 late-phase long-term potentiation (L-LTP) at Schaffer collateral/commissural fiber-CA1 synapses in ra

46 of synaptic transmission was not observed at Schaffer collateral-CA1 synapses, while the submaximal t

47 rences in short- and long-term plasticity at Schaffer collateral (SC) synapses in the dorsal and vent

48 on activity-dependent synaptic plasticity at Schaffer collateral and perforant path synapses in the h

49 ates the induction of synaptic plasticity at Schaffer collateral synapses and hippocampal-dependent l

50 arget cell-specific short-term plasticity at Schaffer collateral synapses in which the activation of

51 II mGlu receptors to synaptic plasticity at Schaffer collateral-CA1 synapses in acute slices of adul

52 uates activity-driven synaptic plasticity at Schaffer collateral-CA1 synapses.

53 f excitatory postsynaptic field potential at Schaffer collateral/commissural fiber-CA1 synapses showe

54 d the induction of long term potentiation at Schaffer collateral synapses.

55 anced induction of long term potentiation at Schaffer-collateral synapses in area CA1 of the hippocam

56 y visualize presynaptic vesicular release at Schaffer collateral-CA1 excitatory synapses in hippocamp

57 ing up the majority of glutamate released at Schaffer collateral-commissural synapses in the hippocam

58 r a potential aspartate-mediated response at Schaffer collateral synapses in organotypic hippocampal

59 the rapidly recycling vesicle pool (RRP) at Schaffer collateral terminals in field CA1 of rat hippoc

60 ansmission and spine density specifically at Schaffer collateral synapses in the stratum radiatum (SR

61 (LTP) induced by theta burst stimulation at Schaffer collateral synapses in the hippocampus.

62 m potentiation (LTP) of synaptic strength at Schaffer collateral synapses has largely been attributed

63 erm depression (LTD) of synaptic strength at Schaffer collateral-CA1 synapses by simultaneously eleva

64 Physiological studies at Schaffer collateral-CA1 synapses uncovered a synaptic fu

65 at perforant path synapses is lower than at Schaffer collateral inputs.

66 eurons, deficits in synaptic transmission at Schaffer collateral synapses, and blunted plasticity and

67 n the strength of excitatory transmission at Schaffer collateral-CA1 cell synapses of the hippocampus

68 -term depression of synaptic transmission at Schaffer collateral-CA1 synapses.

69 tors induces LTD of synaptic transmission at Schaffer collateral-CA1 synapses.

70 ave been shown to potentiate transmission at Schaffer collateral-commissural synapses on CA1 pyramida

71 ansmission and plasticity were unaffected at Schaffer CA1 synapses in mutant mice.

72 Glutamate spillover is observed between Schaffer collateral fiber synapses onto CA1 pyramidal ce

73 ase across a range of Pr at synapses between Schaffer collaterals (SCs) and CA1 pyramidal cells in ac

74 amatergic or GABA-ergic transmission between Schaffer collaterals and CA1 neurons in rat hippocampal

75 cilitated glutamatergic transmission between Schaffer collaterals and CA1 neurons indicated that in a

76 c currents, evoked in CA1 principal cells by Schaffer collateral stimulation, were detected in hippoc

77 amate receptor (mGluR) stimulation either by Schaffer collateral input to CA1 neurones in brain slice

78 duced the amplitude of responses elicited by Schaffer collateral stimulation, without influencing mem

79 inhibits the population spike (PS) evoked by Schaffer collateral stimulation in hippocampal slices.

80 mory and long-term potentiation (LTP) at CA1 Schaffer collateral (SC) synapses.

81 release properties of zinc-positive CA3-CA1 Schaffer collateral/commissural synapses in the stratum

82 dendritic atrophy and LTP attenuation in CA1 Schaffer collateral synapses.

83 issural and mossy fiber synapses but not CA1 Schaffer collateral synapses.

84 esponding to the gamma-paced CA3 output (CA1 Schaffer potentials) and CA3 somatic inhibition within a

85 e dentate perforant path, but not in the CA1 Schaffer collateral pathway.

86 The projections from CA3 to CA1 (Schaffer collaterals), which terminate in the strata rad

87 We provide the first evidence of novel CA3 Schaffer collateral projection to the entorhinal cortex.

88 cture of a single presynaptic input, the CA3 Schaffer pathway, and its contribution to the spontaneou

89 nerated mainly by the entorhinal input, CA3 (Schaffer) collaterals, and voltage-dependent Ca(2+) curr

90 amidal cells and interneurons, the so-called Schaffer-driven spikes, revealing the presynaptic origin

91 ket cells and dendritically projecting, CCK+ Schaffer collateral-associated interneurons.

92 Basket cells, Schaffer-associated and neurogliaform interneurons elici

93 ds preceding the seizure without bursts (cut Schaffer collateral tract) and in comparison with bursts

94 in CA3 pyramidal neurons and its efferents - Schaffer collateral, which causes the depolarization, ac

95 Proline enhanced Schaffer collateral-commissural synaptic transmission ev

96 induction of inflammation revealed enhanced Schaffer collateral-induced excitatory field potentials

97 Bilateral excitatory Schaffer gamma waves are generally larger and lead from

98 denosine receptors at neighboring excitatory Schaffer collateral terminals, which could counteract ef

99 LTP is not elicited in CCK-expressing Schaffer collateral-associated cells, which lack CP-AMPA

100 To counteract this amplitude filtering, Schaffer collateral synapses onto CA1 pyramidal cells co

101 h axons ramifying in the SO and SR; all five Schaffer-associated cells whose axons ramified extensive

102 amidal neurones revealed that high frequency Schaffer collateral stimulation resulted in a prolonged

103 approximately 80% of the synaptic input from Schaffer collaterals.

104 have measured evoked glutamate release from Schaffer collateral/commissural fiber terminals in CA1 b

105 idal cells co-aligned with the glutamatergic Schaffer collateral/commissural input.

106 ial fiber system is a component of the hilar Schaffer collateral system in humans.

107 torhinal perforant path (PP) and hippocampal Schaffer collateral (SC) inputs to CA1 pyramidal cells s

108 has been studied extensively at hippocampal Schaffer collateral (SC) synapses.

109 nt long-term depression (LTD) at hippocampal Schaffer collateral (SC)-CA1 synapses.

110 Our findings show that at hippocampal Schaffer collateral CA3-CA1 synapses, theta-burst LTP re

111 and neurotransmitter release at hippocampal Schaffer collateral synapses in both tottering (tg, alph

112 long-term potentiation (LTP) at hippocampal Schaffer collateral-->CA1 synapses in an activity- and t

113 phase of NMDAR-dependent LTP at hippocampal Schaffer collateral-CA1 (Sch-CA1) synapses.

114 ssion and synaptic plasticity at hippocampal Schaffer collateral-CA1 synapses in adult and juvenile m

115 At hippocampal Schaffer collateral-CA1 synapses, LTD was significantly

116 els of long-term potentiation at hippocampal Schaffer collateral-CA1 synapses.

117 paired long-term potentiation at hippocampal Schaffer collateral-CA1 synapses.

118 on and long-term potentiation at hippocampal Schaffer collateral-CA1 synapses.

119 egulating synaptic plasticity at hippocampal Schaffer collateral-cornu ammonis 1 (SC-CA1) synapses ha

120 ding NMDAR-mediated responses at hippocampal Schaffer collaterals (SC)-CA1 and medial perforant path-

121 contrast, we show that at mature hippocampal Schaffer collateral synapses the magnitudes of Ca2+ tran

122 oach, induced different types of hippocampal Schaffer collateral (SC) to CA1 synaptic plasticity, dep

123 paired cAMP-dependent LTP in the hippocampal Schaffer collateral pathway induced by either forskolin

124 Using a computer model of the hippocampal Schaffer collateral pathway that incorporates evidence f

125 ional knockout (cKO) mice in the hippocampal Schaffer collateral pathway.

126 n the functional dynamics of the hippocampal Schaffer collateral synapse by using data-driven nonpara

127 were obtained with regard to the hippocampal Schaffer collateral synapse.

128 s of long-term depression at the hippocampal Schaffer collateral-CA1 synapse.

129 Field recordings in the hippocampal Schaffer collaterals (SC) pathway revealed significantly

130 s in brain slices by transecting hippocampal Schaffer collaterals and cortical layer I axons.

131 ked in CA1 minislices by sub-threshold 35 Hz Schaffer collateral stimulation that activated fast-spik

132 ombine optogenetic stimulation of identified Schaffer collateral axons with two-photon imaging of pos

133 ey provide a measure of axonal conduction in Schaffer-collateral fibers.

134 -type potassium channels that are present in Schaffer collateral axons and terminals.

135 s is actually decreased despite reduction in Schaffer-evoked inhibition.

136 ium Green AM to measure Ca(2+) transients in Schaffer collateral presynaptic terminals simultaneously

137 n with bursts preceding the seizures (intact Schaffer collateral tract).

138 CA3 waves lock to the ipsilateral Schaffer potentials, although bilateral coherence was we

139 In contrast, AMPAR-mediated input at local Schaffer-collateral synapses on neurogliaform cells rema

140 ippocampus of symptomatic Mecp2(308/Y) mice, Schaffer-collateral synapses exhibited enhanced basal sy

141 n, whereas the release of NPY that modulates Schaffer collateral synapses requires integration of bot

142 ptors (5-HT(1B)Rs), without affecting nearby Schaffer collateral synapses.

143 iated excitation at TA-CA1 synapses, but not Schaffer collateral-CA1 synapses, after CUS, with a corr

144 ired synaptic inputs from entorhinal but not Schaffer-collateral afferents.

145 Notably, Schaffer activity may run laterally, as seen after the d

146 rons depends on the coincident activation of Schaffer collateral and temporoammonic inputs at the dis

147 utamate released by repetitive activation of Schaffer collaterals activates group I metabotropic glut

148 t can be facilitated by modest activation of Schaffer-collateral synapses in the upper apical dendrit

149 odependent mechanism involving activation of Schaffer-specific NMDA receptors and presynaptic inhibit

150 Variance-mean analyses of Schaffer collateral release probability (P(r)) at varyin

151 forming synapses with the impinging axons of Schaffer collateral.

152 tential-evoked [Ca(2+)](i) in the boutons of Schaffer collaterals.

153 dendrites that receive a uniform density of Schaffer collateral input (approximately 100-250 microme

154 tial strength and the short-term dynamics of Schaffer collateral excitatory synapses are regulated by

155 stigate in detail the short-term dynamics of Schaffer collateral excitatory synapses onto CA1 stratum

156 of estradiol on the functional integrity of Schaffer collateral to CA1 (Sch-CA1) pyramidal cell syna

157 B, we measured long-term depression (LTD) of Schaffer-collateral synapses in the hippocampus of c-Rel

158 c deletion of TRPA1 channels affected LTP of Schaffer collateral to CA1 pyramidal neuron synapses.

159 induction of long-term potentiation (LTP) of Schaffer collateral inputs to hippocampal CA1 pyramidal

160 CRS reduced long-term potentiation (LTP) of Schaffer collateral/commisural-CA1 pathway, phospho-alph

161 bserved that stress reduced the magnitude of Schaffer collateral/commissural-Cornu Ammonis field 1 lo

162 tion (LTP) induced by theta-burst pairing of Schaffer collateral inputs and postsynaptic firing is as

163 est that the proline-induced potentiation of Schaffer collateral-commissural synaptic transmission pr

164 on markedly impairs synaptic potentiation of Schaffer collaterals and commissural inputs to the CA1 a

165 ther increase or decrease the probability of Schaffer-collateral (SC)-evoked CA1 spikes.

166 in the fundamental presynaptic properties of Schaffer collateral synapses that could account for dist

167 Prolonged 1 Hz stimulation (900 pulses) of Schaffer collaterals, which normally depresses CA3/CA1 s

168 Eliprodil markedly improved the recovery of Schaffer collateral-CA1 excitatory postsynaptic potentia

169 slices, we find that short trains (2-3 s) of Schaffer collateral fiber stimulation delivered at 5 Hz

170 production of distance-dependent scaling of Schaffer collateral synapses is an elevated postsynaptic

171 nt role in the distance-dependent scaling of Schaffer collateral synapses.

172 pocampal slices after tetanic stimulation of Schaffer collateral synapses.

173 We find that stimulation of Schaffer collateral/commissural fibers in hippocampal sl

174 TP elicited by either tetanic stimulation of Schaffer collaterals or a pairing protocol, and persiste

175 LTP) evoked by high-frequency stimulation of Schaffer collaterals, and that CN2097 attenuates this LT

176 re also evident after tetanic stimulation of Schaffer collaterals.

177 mostly representing excitatory terminals of Schaffer collaterals.

178 ivity at various times after tetanization of Schaffer collateral/commissural-CA1 synapses.

179 The basal synaptic transmission of Schaffer collateral-CA1 neurons was normal but long-term

180 Building on Schaffer's finite population model, we define the large

181 eduction of O-GlcNAc levels had no effect on Schaffer collateral CA1 basal hippocampal synaptic trans

182 the amygdala and examining stress effects on Schaffer collateral/commissural-CA1 LTP and spatial memo

183 CB1Rs are located on Schaffer collateral (Sc) axon terminals in the hippocamp

184 WT mice, but not in Prnp(0/0) mice, pairing Schaffer collateral stimulation with depolarization of C

185 either concentration of proline potentiated Schaffer collateral-commissural synaptic transmission.

186 In presynaptic Schaffer collateral-CA1 terminals of control hippocampal

187 ices in which the cell bodies of presynaptic Schaffer collateral/commissural fibres are removed.

188 (basket cells) or dendritically projecting (Schaffer collateral-associated cells) interneurons and p

189 s long-term potentiation at the CA1 proximal Schaffer collateral synapses when the two inputs are pai

190 as little effect on LTP at the more proximal Schaffer collateral inputs.

191 e magnitude of NMDAR-NR2B conductance at rat Schaffer collateral-CA1 synapses in vitro.

192 ross the range of apical dendrites receiving Schaffer collateral input.

193 Moreover, TRPV1 knockouts have reduced Schaffer collateral LTP, which is rescued by activating

194 The presence of a significant Schaffer collateral system from the pyramidal neurons in

195 theta cycle interval by proximally targeted Schaffer collateral activity, temporoammonic EPSPs propa

196 We found that Schaffer-specific LFPs are composed of a regular success

197 eurons containing somatostatin, we show that Schaffer collateral synapses onto the EGFP-expressing so

198 The Schaffer collateral pathway provides hippocampal CA1 pyr

199 in two separate afferent pathways among the Schaffer collaterals during intracellular recording of C

200 llel fiber to Purkinje cell synapse, and the Schaffer collateral to CA1 pyramidal cell synapse.

201 LTP in mossy fiber (MF)-CA3 pathway and the Schaffer collateral/commissural (SC)-CA1 pathway differ

202 t path (PP) of the entorhinal cortex and the Schaffer collaterals (SCs) from individual CA3 pyramidal

203 ly mGlu7 is expressed presynaptically at the Schaffer collateral (SC)-CA1 synapse in the hippocampus

204 forms of long-term potentiation (LTP) at the Schaffer collateral CA1 synapse require stimulation of b

205 receptors modulate synaptic function at the Schaffer collateral input to CA1 pyramidal cells, thereb

206 report similar changes in plasticity at the Schaffer collateral pathway in alert behaving mice.

207 icited by such heterosynaptic pairing at the Schaffer collateral synapse in mice.

208 ng-term synaptic potentiation (L-LTP) at the Schaffer collateral synapse of the hippocampus is an exp

209 activity induces synaptic plasticity at the Schaffer collateral synapse onto CA1 pyramidal neurones.

210 tential diversity of nAChR influences at the Schaffer collateral synapse onto CA1 pyramidal neurons.

211 N-type voltage-gated Ca(2+) channels at the Schaffer collateral than perforant path synapses.

212 tate gyrus as well as decremental LTP at the Schaffer collateral-->CA1 pyramidal cell synapse.

213 PG-induced inhibition of transmission at the Schaffer collateral-->CA1 synapse.

214 F-dependent long-lasting potentiation at the Schaffer collateral-CA1 synapse in hippocampus.

215 iation (LTP) of synaptic transmission at the Schaffer collateral-CA1 synapse in the hippocampus is su

216 Long-term potentiation (LTP) at the Schaffer collateral-CA1 synapse involves interacting sig

217 e to block agonist-mediated responses at the Schaffer collateral-CA1 synapse, a location at which neu

218 nhibition of group III mGluR function at the Schaffer collateral-CA1 synapse.

219 We examined this question at the Schaffer collateral-CA1 synapses in slices of mouse hipp

220 z/1 s) in control slices elicited LTP at the Schaffer collateral-CA1 synapses, but neither LTP nor LT

221 remental long-term potentiation (LTP) at the Schaffer collateral-CA1 synapses.

222 Long-term potentiation (LTP) at the Schaffer collateral-commissural synapses in the CA1 area

223 otentiation of long-term potentiation at the Schaffer collateral/cornu ammonis 1 synapse in the dorsa

224 synaptic plasticity was investigated at the Schaffer-collateral-CA1 pyramidal cell synapse of mouse

225 ctionally important interactions between the Schaffer collateral and perforant pathways have been hyp

226 he efficacy of neurotransmission between the Schaffer collateral-CA1 pathway in the rat transverse hi

227 al synapses requires integration of both the Schaffer collateral and temporoammonic pathways.

228 gh CA3 pyramidal cells give rise to both the Schaffer collateral fiber synapses in CA1 and the assoc-

229 opment, basic synaptic transmission from the Schaffer collateral pathway to CA1 pyramidal neurons rem

230 P16-CREB, enhanced in vivo LTP evoked in the Schaffer collateral pathway and caused significant chang

231 Long-term potentiation (LTP) in the Schaffer collateral pathway from the CA3 to the CA1 regi

232 Neuronal stimulation in the Schaffer collateral pathway promotes pS857 dephosphoryla

233 rine) on input-output (I-O) relations in the Schaffer collateral pathway to CA1 (SC-CA1) and mossy fi

234 y-phase LTP to late-phase LTP (L-LTP) in the Schaffer collateral pathway, likely as a result of incre

235 ircuit-specific and were not observed in the Schaffer collateral pathway-associated inhibitory synaps

236 circuit-specific and are not observed in the Schaffer collateral pathway-associated inhibitory synaps

237 ase of long-term potentiation (L-LTP) in the Schaffer collateral pathway.

238 ase of long-term potentiation (L-LTP) in the Schaffer collateral pathway.

239 phase of long-term potentiation (LTP) in the Schaffer collateral pathway.

240 ession and facilitation were apparent in the Schaffer collateral synapse.

241 d that deletion of Cdc42 impaired LTP in the Schaffer collateral synapses and postsynaptic structural

242 be related to impairment of the E-LTP in the Schaffer collateral synapses but not of that of the perf

243 and -independent forms of LTP induced in the Schaffer collateral to CA1 synapses.

244 erm potentiation (LTP) can be induced in the Schaffer collateral-->CA1 synapse of hippocampus by stim

245 sion and long-term potentiation (LTP) in the Schaffer Collateral-CA1 and the mossy fiber-CA3 pathways

246 as enhanced paired-pulse facilitation in the Schaffer Collateral-CA1 glutamatergic synapses of the cb

247 implanted with stimulating electrodes in the Schaffer collaterals and with recording electrodes in th

248 gh and low levels of nAChR activation in the Schaffer collaterals inhibit and facilitate, respectivel

249 pecifically and quickly to affect LTP in the Schaffer collaterals of the hippocampus.

250 at hippocampal long-term potentiation in the Schaffer collaterals was identical in homozygous, hetero

251 very different time-varying responses in the Schaffer-commissural projections than in the lateral per

252 One week after transection of the Schaffer collateral and temporoammonic afferents to CA1

253 PSPs evoked by electrical stimulation of the Schaffer collateral inputs.

254 Here we show that tetanic stimulation of the Schaffer collateral pathway causes an increase in the co

255 We suggest that tetanic stimulation of the Schaffer collateral pathway may induce new synthesis of

256 tratum radiatum following stimulation of the Schaffer collateral pathway.

257 hippocampal slices after tetanization of the Schaffer collateral pathway.

258 y processes or long-term potentiation of the Schaffer collateral pathway.

259 requency electrical stimulation (LFS) of the Schaffer collateral pathway.

260 esynaptic and postsynaptic components of the Schaffer collateral synapse.

261 These results suggest that part of the Schaffer collateral synaptic response has pharmacologica

262 h that under intact pharmacology, LTP of the Schaffer collateral to CA1 pyramidal neuron synapses wil

263 Through electrophysiological analysis of the Schaffer collateral-CA1 synapse in dorsal hippocampus, w

264 Brief stimulation of the Schaffer collaterals elicited an alkaline pH(e) transien

265 egion of the hippocampus, stimulation of the Schaffer collaterals elicits an alkaline pH(e) transient

266 We found that orthodromic stimulation of the Schaffer collaterals for 10 min reduces the amplitude of

267 In hippocampus, activation of the Schaffer collaterals generates an extracellular alkaline

268 SCs) evoked by electrical stimulation of the Schaffer collaterals in CA1 hippocampal pyramidal cells.

269 ease during low-frequency stimulation of the Schaffer collaterals were altered in scrapie-infected mi

270 in hippocampal slices by stimulation of the Schaffer collaterals, an excitatory fibre tract that pro

271 sociated with the axons and terminals of the Schaffer collaterals.

272 rea CA1 following tetanic stimulation of the Schaffer collaterals.

273 tion spike by orthodromic stimulation of the Schaffer collaterals.

274 ippocampus in response to stimulation of the Schaffer collaterals.

275 in response to electrical stimulation of the Schaffer collaterals.

276 no expression within the perforant path, the Schaffer collaterals, or neuronal cell bodies.

277 was tested with use of one such pathway, the Schaffer collateral-commissural projection to CA1 pyrami

278 were determined in acute brain sections; the Schaffer collateral pathway was stimulated and the field

279 We stimulated the Schaffer collateral/commissural fibers in acute hippocam

280 CA or sham-operated rats by stimulating the Schaffer collaterals and recording in the CA1 pyramidal

281 ed before (control) and after tetanizing the Schaffer/collateral commissural pathway.

282 gic and has a larger NMDA component than the Schaffer collateral (sc) input.

283 ected animals after 5 months showed that the Schaffer collateral-evoked EPSP was attenuated, the effe

284 of the normal CA3 outflow tract through the Schaffer collaterals are well known, their aberrant reor

285 tion of various stimulation protocols to the Schaffer collateral/commissural projections in freely mo

286 paired-pulse stimulation was applied to the Schaffer collaterals and population spikes were monitore

287 oammonic (TA) pathway and indirectly via the Schaffer collateral (SC) pathway from CA3.

288 nged in epileptic animals, and input via the Schaffer collaterals is actually decreased despite reduc

289 the perforant path (PP) and from CA3 through Schaffer collaterals (SC).

290 e perforant path (PP) and indirectly through Schaffer collaterals (SC).

291 m potentiation (LTP) when locally applied to Schaffer collateral-CA1 synapses.

292 Evoked responses of CA1 neurons to Schaffer collateral stimulation changed over the cycle,

293 atio onto CA1 pyramidal cells in response to Schaffer collateral stimulation in slices from young adu

294 ratio of CA1 pyramidal cells in response to Schaffer collateral stimulation.

295 udies revealed that the amplitude of unitary Schaffer collateral inputs increases with distance from

296 The present findings show that, using Schaffer collateral stimulation, the effects of SNX and

297 mission and plasticity at dorsal and ventral Schaffer collateral (SC) synapses in the mouse hippocamp

298 e reported conflicting results as to whether Schaffer collateral axons have target-cell specific shor

299 ine (10 microM) enhanced NMDAR currents with Schaffer collateral stimulation in WT mice but not HZ mi

300 g of back-propagating action potentials with Schaffer collateral EPSPs was accompanied by an overall