ライフサイエンスコーパス: Shigella

1 151 diverse E. coli isolates incorrectly as Shigella.

2 d modules for membrane antigens (GMMA), from Shigella.

3 is located on the large virulence plasmid of Shigella.

4 n different steps of the invasive process of Shigella.

5 action of MSD cases that are attributable to Shigella.

6 irulence genes icsA, virB, icsB, and ipaB in Shigella.

7 says and found that SE-1 reduced invasion by Shigella.

8 -expression of heat-labile enterotoxin), and Shigella.

9 ens were positive by traditional culture for Shigella.

10 ears) with dysentery or laboratory-confirmed Shigella.

11 haea, and 72 strains of Escherichia coli and Shigella.

12 ria, Staphylococcus, Klebsiella, Proteus and Shigella.

13 Intestinal pathogens Shigella (36%), Giardia (33%), and Campylobacter (30%) p

14 cases (Campylobacter: 738, Salmonella: 624, Shigella: 376, Yersinia: 17) were identified and followe

15 Shigella, a major diarrheal disease pathogen worldwide,

16 Unlike apoptotic stimuli, Shigella activates the calpain-dependent cleavage of BID

17 iagnostic value, and antibiotic treatment of Shigella and dysentery), and meta-analyses where appropr

18 Phylogeny inferred from 336 available Shigella and Escherichia coli genomes defined exclusive

19 mplications for virulence gene regulation in Shigella and other pathogens that control gene expressio

20 and reliably detected Salmonella, EHEC O157, Shigella, and Campylobacter at concentrations 1- to 2-lo

21 , Giardia, enterotoxigenic Escherichia coli, Shigella, and Campylobacter.

22 c relationships between different species of Shigella, and identified emerging pathoadapted lineages.

23 and an increase in Enterobacter, Escherichia/Shigella, and Pseudomonas in stool after ABX + DS for 10

24 ance in Escherichia, Salmonella, Klebsiella, Shigella, and Yersinia opportunistic pathogens, the stru

25 incorporates both of these previously tested Shigella antigens into a single polypeptide chain.

26 d accurately identifying the four species of Shigella are therefore challenging.

27 by a conserved gatekeeper protein, MxiC, in Shigella As its molecular mechanism of action is still p

28 porter gene assays with Escherichia coli and Shigella, as well as in vitro DNA binding assays with pu

29 hogens, such as Salmonella, Escherichia, and Shigella, as well as ubiquitin/ubiquitin-like cross-reac

30 While Shigella assembles its T3SS when the environmental condi

31 aimed to systematically review and evaluate Shigella-associated and dysentery-associated mortality,

32 nfection might miss an opportunity to reduce Shigella-associated morbidity and mortality.

33 eneity was reported for meta-analyses of the Shigella-associated mortality studies (I(2)=78.3%) and d

34 The Shigella autotransporter protein IcsA, which is localize

35 bundances of Pseudobutyrivibrio, Escherichia/Shigella, Blautia, and Streptococcus, while relative abu

36 7:H7 and non-O157 EHEC strains as well as in Shigella boydii Furthermore, a truncated version of EspW

37 with increases in Bilophila and Escherichia/Shigella but a decrease in Faecalibacterium.

38 to culture for the detection of Salmonella, Shigella, Campylobacter, and Shiga toxin-producing enter

39 or each of enterotoxigenic Escherichia coli, Shigella, Campylobacter, Cryptosporidium, norovirus GII,

40 Shigella can be differentiated from E. coli and accurate

41 ted for 5.0% and 5.4%, respectively, of 1130 Shigella case isolates; S. flexneri comprised 65.9% and

42 We were able to identify 90% of E. coli and Shigella clinical isolates correctly to the species leve

43 While many aspects of Shigella colonic cell invasion are known, crucial gaps i

44 Suspect Shigella colonies were identified by biochemical tests a

45 hia coli genomes defined exclusive clades of Shigella; conserved genomic markers that can identify ea

46 ria antagonize these responses; for example, Shigella delivers OspC3 to inhibit caspase-4, a potentia

47 Furthermore, Shigella-dependent replication of Bdellovibrio was captu

48 Shigella dysenteriae and S. boydii accounted for 5.0% an

49 A previous genomic study concluded that Shigella dysenteriae type 1 (Sd1), the epidemic dysenter

50 against Escherichia coli, Salmonella typhi, Shigella dysenteriae, Streptococcus pneumoniae and Staph

51 Here, we found that the Shigella effector protein IpaJ potently inhibits STING s

52 dition, several enteropathogenic E. coli and Shigella effectors were found to inactivate members of t

53 e cultures for Campylobacter, Salmonella, or Shigella entero-pathogens in traditional culturing metho

54 chia coli (AF, 18.4% [95% CI, 12.9%-21.9%]), Shigella/enteroinvasive E. coli (AF, 14.5% [95% CI, 10.2

55 [EPEC], and Shiga-toxigenic E. coli [STEC]), Shigella/enteroinvasive E. coli (EIEC), protozoa (Crypto

56 cing E. coli (OR: 1.55; 95% CI: 1.04, 2.33), Shigella/enteroinvasive E. coli (OR: 1.65; 95% CI: 1.10,

57 a, the major virulence factor of the strain, Shigella enterotoxin 1, H4 flagellin, and O104 lipopolys

58 ination with bacterial genetics explains how Shigella evades a broad spectrum of immune surveillance

59 Our data demonstrate for the first time that Shigella evades the XIAP-mediated immune response by ind

60 This ubiquitin coating of Shigella favors the pathogen as it liberates bacteria fr

61 olysaccharide of the Gram-negative bacterium Shigella flexneri (S. flexneri) as a first step of bacte

62 g unit from the O-specific polysaccharide of Shigella flexneri 2a, a major cause of bacillary dysente

63 regative and uropathogenic Escherichia coli, Shigella flexneri 2a, and the hybrid enteroaggregative/S

64 re observed for the NleE homologue OspZ from Shigella flexneri 6 that also bound TAB3 through the (49

65 ected the transcriptional immune response to Shigella flexneri across different infection stages in b

66 The protective efficacy was 70% against Shigella flexneri and 50% against Shigella sonnei.

67 Intracellular pathogens such as Shigella flexneri and Listeria monocytogenes achieve dis

68 retained the ability to protect mice against Shigella flexneri and S. sonnei in the lethal pulmonary

69 e leading cause of bacterial dysentery, with Shigella flexneri and Shigella sonnei accounting for aro

70 of the cytoplasmic regions of the vT3SSs of Shigella flexneri and the vT3SS and fT3SS of Salmonella

71 acter rodentium, Salmonella typhimurium, and Shigella flexneri are sensed in an ill-defined manner by

72 arized epithelial Caco-2 cell monolayers and Shigella flexneri as a model enteropathogen, we found th

73 Shigella flexneri can be phenotypically serotyped using

74 The tip complex of Shigella flexneri contains invasion plasmid antigen D (I

75 entify candidate interaction partners of the Shigella flexneri effector proteins OspE1 and OspE2, whi

76 contrast, the professional cytosol-dwelling Shigella flexneri escapes from LUBAC-mediated restrictio

77 ield showing that Listeria monocytogenes and Shigella flexneri have evolved pathogen-specific mechani

78 Yersinia pestis YapV is homologous to Shigella flexneri IcsA, and like IcsA, YapV recruits mam

79 y of guanylate-binding proteins (GBPs) coats Shigella flexneri in a hierarchical manner reliant on GB

80 els of enteropathogenic Escherichia coli and Shigella flexneri infection, WASp deficiency causes defe

81 nal structure of Yersinia enterocolitica and Shigella flexneri injectisomes in situ and the first str

82 The guinea pig model for Shigella flexneri invasion of the colonic mucosa was use

83 Shigella flexneri is a bacterial pathogen that invades c

84 Shigella flexneri is a Gram-negative intracellular patho

85 The LPS of the enteropathogen Shigella flexneri is a hexa-acylated isoform possessing

86 ing the putative NF-T3SS C-ring component in Shigella flexneri is alternatively translated to produce

87 Shigella flexneri is an intracellular pathogen that diss

88 e of the type-III secretion system needle of Shigella flexneri is determined to a precision of 0.4 A.

89 The Gram-negative enteroinvasive bacterium Shigella flexneri is responsible for the endemic form of

90 h-quality reference genome of the historical Shigella flexneri isolate NCTC1 and to examine the isola

91 e show that the type III effector IpgB1 from Shigella flexneri may bind to acidic phospholipids and r

92 E. coli isolates that were misidentified as Shigella flexneri or S. boydii by the kmer ID, and 8 wer

93 Shigella flexneri proliferate in infected human epitheli

94 Recently, the Shigella flexneri protease IpaJ was found to cleave myri

95 Mutations in vps or vacJ in Shigella flexneri resulted in increased sensitivity to l

96 mic analysis, we sequenced the oldest extant Shigella flexneri serotype 2a isolate using single-molec

97 whole-genome sequenced clinical isolates of Shigella flexneri serotype 3a from high-risk and low-ris

98 s research highlighting induced virulence in Shigella flexneri strain 2457T following exposure to bil

99 Global proteomic analysis was performed with Shigella flexneri strain 2457T in association with three

100 ) to visualize intact machines in a virulent Shigella flexneri strain genetically modified to produce

101 htrB, in GMMA-producing Shigella sonnei and Shigella flexneri strains.

102 The human pathogen Shigella flexneri subverts host function and defenses by

103 Shigella flexneri two-component regulatory systems (TCRS

104 Pseudomonas aeruginosa covalently linked to Shigella flexneri type 2a O-antigen (Sf2E) produced by e

105 tigen J (IpaJ), a previously uncharacterized Shigella flexneri type III effector protein with cystein

106 report the identification of two homologous Shigella flexneri type III secretion system effector E3

107 a pig model increased bacterial clearance of Shigella flexneri upon colonic infection, strongly sugge

108 tro, plasma-derived IgA and SIgA neutralized Shigella flexneri used as a model pathogen, resulting in

109 , SsaG (Salmonella enterica SPI-2), or MxiH (Shigella flexneri).

110 ng Escherichia coli, Salmonella typhimurium, Shigella flexneri, and Burkholderia thailandensis activa

111 Since Listeria monocytogenes, Shigella flexneri, and Vaccinia virus among other pathog

112 esponse against the enteroinvasive bacterium Shigella flexneri, both in vitro and in vivo.

113 t attachment and invasion by deoxycholate in Shigella flexneri, deoxycholate negatively regulates Ics

114 vivo studies with three omp null mutants of Shigella flexneri, including classic phage plaque assays

115 ted with invasion and cell-to-cell spread by Shigella flexneri, including multiple components of the

116 ETEC and other enteric pathogens, including Shigella flexneri, that express similar proteins.

117 Here, we show that infection by Shigella flexneri, the causative agent of human bacillar

118 Using bacteriophage Sf6 and its host, Shigella flexneri, we investigated how Sf6 utilizes oute

119 Shigella flexneri, which replicates in the cytoplasm of

120 or virulence of the human diarrheal pathogen Shigella flexneri.

121 estigated its regulation by H-NS and VirB in Shigella flexneri.

122 iotic-resistant strain of the human pathogen Shigella flexneri.

123 ated bacteria (Escherichia coli, Salmonella, Shigella flexnerii and Staphylococcus aureus).

124 glennhickey/progressiveCactus The E.coli and Shigella genome hub is now a public hub listed on the UC

125 bly hub containing 57 Escherichia coli and 9 Shigella genomes and show examples that highlight their

126 The Escherichia/Shigella genus encompasses a great variety of commensal

127 -resistant strain, Ty21a-AR-Ss, by inserting Shigella glutaminase-glutamate decarboxylase systems coe

128 ase burden and the emerging threats posed by shigella have accelerated interest in development of shi

129 Of note, one VHH heterodimer could reduce Shigella hemolytic activity by >80%.

130 flammation caused by the invasion process of Shigella in colonic and rectal mucosa.

131 lled signal amplification was used to detect Shigella in stool and blood matrixes at the single-digit

132 ed a quantitative PCR (qPCR) assay to detect Shigella in the stool samples of 3,533 children aged <59

133 significantly decreased, whereas Escherichia-Shigella increased with reduction of protein concentrati

134 tions accumulate in a long-lasting manner in Shigella-infected cells, causing subsequent formation of

135 inflammasome-mediated release of IL-1beta in Shigella-infected macrophages; and (vi) iLPS exhibits a

136 d. vaccination with IpaB and IpaD to prevent Shigella infection and support further studies in humans

137 ction of MSD cases that were attributable to Shigella infection increased from 9.6% (n = 129) for cul

138 sentery for identification and management of Shigella infection might miss an opportunity to reduce S

139 Shigella infection was associated with mortality (pooled

140 value of dysentery for the identification of Shigella infection, and the efficacy of antibiotics for

141 dentified that surface loops of OmpA mediate Shigella infection.

142 lgi-associated ARF/ARL family GTPases during Shigella infection.

143 for the reduction of immune responses during Shigella infection.

144 e intestine by 24 hours post-intraperitoneal Shigella infection.

145 e; however, adult mice are resistant to oral Shigella infection.

146 protective efficacy against intraperitoneal Shigella infection.

147 tic therapy for children with non-dysenteric Shigella infection.

148 n to be altered during the course of natural Shigella infection.

149 Shigella infections are a leading cause of diarrhoeal de

150 dysentery identified 1.9-85.9% of confirmed Shigella infections, with sensitivity decreasing over ti

151 Ciprofloxacin is a recommended treatment for Shigella infections.

152 Shigella infects via the fecal-oral route, and its virul

153 learance, and in the entry of Salmonella and Shigella into cells.

154 The crucial role of this pathway for Shigella intracellular growth suggests targets for antim

155 In addition to cell death occurring in Shigella-invaded CL-01 B lymphocytes, we provide evidenc

156 combined with an amplicon for the conserved Shigella invasion antigen, IpaH3, into a multiplex PCR a

157 gle protein component of the T3SA translocon-Shigella IpaC, Salmonella SipC, or Chromobacterium CipC-

158 Apoptotic B lymphocytes in contact with Shigella-IpaD are detected in rectal biopsies of infecte

159 ventional culture to those from qPCR for the Shigella ipaH gene.

160 The enteroinvasive bacterium Shigella is a facultative intracellular bacterium known,

161 We unveil that (i) Shigella is able to modify the LPS composition, e.g., th

162 Shigella is one of the leading pathogens contributing to

163 ble tool for rapid typing of uncharacterized Shigella isolates and provides a framework that can be u

164 onships between antibiotic susceptibility of Shigella isolates and travel destination or other risk f

165 patterns and risk factors for acquisition in Shigella isolates using routinely collected data for not

166 Shigella isolates were shipped to the GEMS Reference Lab

167 ents notified during the study period, where Shigella isolates were tested for antimicrobial sensitiv

168 correctly identifying 218 of 221 presumptive Shigella isolates, and sensitivity, by not identifying a

169 Shigella, like many other Gram-negative bacterial pathog

170 s that the hydrophobic translocator (IpaB in Shigella) likely binds to a region within the tip protei

171 era, Mycobacterium, Salmonella, Escherichia, Shigella, Listeria and Bartonella, using published liter

172 cytosolic bacteria, including Burkholderia, Shigella, Listeria, Francisella, and Mycobacterium speci

173 essed the question of the role played by the Shigella LPS in eliciting a dysregulated inflammatory re

174 sional intracytoplasmic pathogens, including Shigella, mediate phagosomal escape.

175 Shigella mediates intracellular motility and spreading v

176 at co-expression of full-length IcsA and the Shigella membrane protease IcsP yields highly pure IcsA

177 nd genetic experiments to determine host and Shigella metabolism during infection in a cell culture m

178 x and modulated the infectious properties of Shigella Moreover, structural elucidation of several Ipa

179 tire output of these pathways is captured by Shigella, most likely in the form of pyruvate.

180 erica needle proteins PrgI and SsaG, and the Shigella needle protein, MxiH.

181 The demonstrated ultrasensitive detection of Shigella on the single-digit CFU level suggests the feas

182 he efficacy of antibiotics for children with Shigella or dysentery, or both.

183 of a gene and pathway previously unknown in Shigella pathogenesis and provides a framework for furth

184 la virulence plasmid and, in some cases, the Shigella pathogenicity islands.

185 ial (eg, enteroaggregative Escherichia coli, Shigella) pathogens.

186 that the proximity of VirB binding sites to Shigella promoters does not necessarily correlate with t

187 urthermore, we describe a mechanism by which Shigella promotes its own invasion by altering the sumoy

188 ion of zebrafish containing a lethal dose of Shigella promotes pathogen killing, leading to increased

189 ny pathogens, including the genera Yersinia, Shigella, Pseudomonas, and Salmonella, to deliver effect

190 Like many Gram-negative pathogens, Shigella rely on a complex type III secretion system (T3

191 Although it is clear that Shigella requires N-WASP for this process, the molecular

192 reactivity studies were conducted by testing Shigella, Salmonella spp., Salmonella typhimurium and St

193 f the translocator components of the T3SA of Shigella, Salmonella, and Chromobacterium, we demonstrat

194 Enterobacteriaceae (SPATEs) are secreted by Shigella, Salmonella, and Escherichia coli pathotypes.

195 Here we showed that Shigella, Salmonella, and Listeria interfere with splice

196 TLR2 agonists, i.e., porins from Neisseriae, Shigella, Salmonella, Haemophilus influenzae, and Fusoba

197 GEMS Shigella serotypes are reviewed to guide vaccine develop

198 pecific multidrug-resistant (MDR) lineage of Shigella sonnei (lineage III) is becoming globally domin

199 terial dysentery, with Shigella flexneri and Shigella sonnei accounting for around 90% of cases world

200 Shigella sonnei and Salmonella Typhi cause significant m

201 erase genes, msbB or htrB, in GMMA-producing Shigella sonnei and Shigella flexneri strains.

202 analyze the largest surveillance data set of Shigella sonnei in the United States from 1967 to 2007 w

203 Shigella sonnei is a bacterial pathogen and causative ag

204 Shigella sonnei is a human-adapted pathogen that is emer

205 lt males, characterized by distinct periodic Shigella sonnei outbreaks.

206 The current Shigella sonnei pandemic involves geographically associa

207 al analysis of poly- and oligosaccharides of Shigella sonnei phase II ECA(LPS).

208 ocytogenes, Salmonella entericaserovartyphi, Shigella sonnei, Campylobacter jejuni and Helicobacter p

209 horylation intermediate (E2.Pi) of ZntA from Shigella sonnei, determined at 3.2 A and 2.7 A resolutio

210 0% against Shigella flexneri and 50% against Shigella sonnei.

211 Of the 1,982 Escherichia coli and Shigella sp. isolates analyzed in this study, 1,957 (98.

212 Common Structural Antigen, Listeria sp., and Shigella sp., dose-response curves were obtained, and li

213 ences of Vibrio cholerae, Salmonella sp. and Shigella sp., which cause diarrheal diseases.

214 e genetic algorithm to differentiate between Shigella species and E. coli.

215 of E. coli are biochemically very similar to Shigella species and thus pose a greater diagnostic chal

216 Escherichia coli and Shigella species are closely related and genetically con

217 Shigella species are so closely related to Escherichia c

218 The Shigella species cause millions of cases of watery or bl

219 Shigella species Gram-negative bacteria which cause a di

220 s, few studies on the genomic content of the Shigella species have been completed.

221 From 2000 to 2012, Vibrio cholerae O1 and Shigella species isolates from urban Dhaka and rural Mat

222 was to characterize the genomic diversity of Shigella species through sequencing of 55 isolates repre

223 In contrast to isolates of the four Shigella species, which are widespread and can be freque

224 nomes from each of the E. coli pathovars and Shigella species.

225 hanism nearly indistinguishable from that of Shigella species.

226 streamline the identification of E. coli and Shigella species.

227 flexneri isolates but not in the three other Shigella species.

228 ing the terminal ileum, colon, and rectum by Shigella species.

229 norovirus genogroup II, Cryptosporidium, and Shigella species/enteroinvasive Escherichia coli were si

230 tes representing members of each of the four Shigella species: S. flexneri, S. sonnei, S. boydii, and

231 %, 4.4-5.2), astrovirus (4.2%, 3.5-4.7), and Shigella spp (4.0%, 3.6-4.3).

232 at-stable enterotoxigenic E coli, rotavirus, Shigella spp and enteroinvasive E coli, and Vibrio chole

233 ected and 2063 (38.9%) had two or more, with Shigella spp and rotavirus being the pathogens most stro

234 For example, Shigella spp at a Cq range of 15-20 had an odds ratio of

235 ly for adenovirus 40/41 (around five times), Shigella spp or enteroinvasive Escherichia coli (EIEC) a

236 marily associated with Campylobacter spp and Shigella spp, fever and vomiting with rotavirus, and vom

237 table pathogens became, in descending order, Shigella spp, rotavirus, adenovirus 40/41, ST-ETEC, Cryp

238 E. coli (stx2), Campylobacter jejuni (mapA), Shigella spp. (ipaH), and a Salmonella enterica-specific

239 hogens Shiga-toxin producing E. coli (STEC), Shigella spp. , Salmonella spp , Campylobacter jejuni/co

240 Sixty-six Shigella spp. and 72 E. coli isolates were used to gener

241 Shigella spp. are causative agents of bacillary dysenter

242 Estimates of the prevalence of Shigella spp. are limited by the suboptimal sensitivity

243 Pathogenic Shigella spp. are the leading cause of bacterial dysente

244 In human and nonhuman primates, Shigella spp. cause bacillary dysentery by invading colo

245 Shigella spp. cause shigellosis, also called bacillary d

246 about 90 million people become infected with Shigella spp. each year.

247 OspG, a Shigella spp. effector kinase, plays a role in this proc

248 protein of the type III secretion system in Shigella spp. that downregulates the human inflammatory

249 .2% for Salmonella spp., 99.1% and 99.7% for Shigella spp., 97.2% and 98.4% for C. jejuni and C. coli

250 9.8% for Salmonella spp., 99.2% and 100% for Shigella spp., 97.5% and 99.0% for C. jejuni and C. coli

251 ns IpaB and IpaD, which are conserved across Shigella spp., are candidates for a broadly protective,

252 ulture for the detection of Salmonella spp., Shigella spp., Campylobacter jejuni, and Campylobacter c

253 oli (ETEC), enteropathogenic E. coli (EPEC), Shigella spp., Campylobacter jejuni, Salmonella enterica

254 ttributed to Salmonella (nontyphoidal) spp., Shigella spp., Campylobacter spp. or Yersinia enterocoli

255 eria (Campylobacter jejuni, Salmonella spp., Shigella spp., enterotoxigenic Escherichia coli [ETEC],

256 erall, the standard culture methods detected Shigella spp., EPEC, ETEC, and EAEC in smaller proportio

257 er spp., Enterobacter spp., Escherichia coli/Shigella spp., Klebsiella oxytoca, Klebsiella pneumoniae

258 ens, including Vibrio spp., Salmonella spp., Shigella spp., Yersinia spp., Citrobacter spp., enteroto

259 cluding specific detection of E. coli O157), Shigella spp./enteroinvasive E. coli, Cryptosporidium sp

260 rdia lamblia; 94% for ETEC and STEC; 93% for Shigella spp.; 92% for Salmonella spp.; 91% for C. diffi

261 Norovirus GII, Cryptosporidium, Shigella, ST-ETEC, and adenovirus 40/41 were also import

262 entions targeting five pathogens (rotavirus, Shigella, ST-ETEC, Cryptosporidium, typical enteropathog

263 rcontinental dissemination of multiresistant shigella strains, facilitated by travellers and men who

264 for 55 fully sequenced Escherichia coli and Shigella strains.

265 s into how exposure to bile likely regulates Shigella survival and virulence during host transit and

266 The Shigella T3SS consists of a hollow needle, made of MxiH

267 uely complementing the multitude of included Shigella T3SS phenotype assays and providing a more comp

268 nts of the exposed needle tip complex of the Shigella T3SS, invasion plasmid antigen D (IpaD) and Ipa

269 eted effector kinase from the human pathogen Shigella that is required for the reduction of immune re

270 Antibody-mediated immunity to Shigella, the causative agent of bacillary dysentery, re

271 ontinental spread of antimicrobial-resistant shigella through established transmission routes emphasi

272 The Shigella tip complex (TC) is composed of IpaD, a hydroph

273 vantage of the ability of the enteropathogen Shigella to convert the phosphothreonine residue of the

274 eting to the diversity of mechanisms used by Shigella to dampen the host immune response.

275 the transcriptional regulation necessary for Shigella to effectively adapt to the mammalian host cell

276 only mechanism, is the main strategy used by Shigella to target human immune cells.

277 Escherichia coli, Salmonella, Yersinia, and Shigella, to subvert cell signaling and host responses.

278 ratin 18 interact with the C-terminus of the Shigella translocon pore protein IpaC.

279 knowledge, a direct physiologic role for the Shigella type III secretion apparatus (T3SA) in mediatin

280 relates precisely with the activation of the Shigella type III secretion apparatus, thus evidencing i

281 The molecular architecture of the Shigella type III secretion machine and its sorting plat

282 Shigella type III secretion system proteins IpaB and Ipa

283 strate that the introduction of a functional Shigella type III secretion system, but none of its effe

284 l imaging of infected zebrafish reveals that Shigella undergo rounding induced by the invasive predat

285 human colonic lamina propria, encountered by Shigella upon its crossing of the mucosal barrier, are a

286 Shigella uses a simple three-step pathway to metabolize

287 sm of bacillary dysentery and for evaluating Shigella vaccine candidates.

288 w the feasibility of generating a protective Shigella vaccine comprised of the DB fusion.

289 A broad-spectrum Shigella vaccine must protect against S. sonnei and 15 S

290 have accelerated interest in development of shigella vaccines, many of which are being tested in cli

291 In silico detection of the Shigella virulence plasmid (pINV), which is essential fo

292 neages of E. coli via the acquisition of the Shigella virulence plasmid and, in some cases, the Shige

293 a proper translocator secretion profile, and Shigella virulence.

294 Shigella was 1 of the 4 most common pathogens across sit

295 Inactivated Shigella was spiked in these matrixes and detected direc

296 re and its similarity with that of MxiC from Shigella, we definitively confirm CopN as the Chlamydia

297 educe mortality among children infected with Shigella who present without bloody stool.

298 This striking strategy provides Shigella with an abundant favorable energy source, while

299 f SE-1 on invasion required preincubation of Shigella with SE-1, in agreement with the hypothesis tha

300 bacteria, including Salmonella, Escherichia, Shigella, Yersinia, Pseudomonas, and Chlamydia spp.