ライフサイエンスコーパス: Sjogren syndrome

1 ed often-undiagnosed systemic disease (e.g., Sjogren syndrome).

2 both the dystroglycanopathies and Marinesco-Sjogren syndrome.

3 e diseases, including systemic sclerosis and Sjogren syndrome.

4 rrelated with other diagnostic components of Sjogren syndrome.

5 se in a neurodegenerative model of Marinesco-Sjogren syndrome.

6 ted in several autoimmune disorders, such as Sjogren syndrome.

7 a diagnosis of lupus erythematosus and 1 had Sjogren syndrome.

8 nvolved in cystic fibrosis, pancreatitis, or Sjogren syndrome.

9 targets, which may be relevant for childhood Sjogren syndrome.

10 ollowing targeted head and neck radiation or Sjogren syndrome.

11 tory diseases such as acute pancreatitis and Sjogren syndrome.

12 ment of patients with acute pancreatitis and Sjogren syndrome.

13 nitis and are a model for the human disorder Sjogren syndrome.

14 d systemic autoimmunity resembling lupus and Sjogren syndrome.

15 ients with pulmonary complications of RA and Sjogren syndrome.

16 ulcerative colitis), psoriasis, and primary Sjogren syndrome.

17 wn some benefit in rheumatoid vasculitis and Sjogren syndrome.

18 sms responsible for tear film instability in Sjogren syndrome.

19 rimal gland inflammation that is a model for Sjogren syndrome.

20 various infectious agents in both lupus and Sjogren syndrome.

21 ti-exocrine gland pathology similar to human Sjogren syndrome.

22 tal lupus, systemic lupus erythematosus, and Sjogren syndrome.

23 ts had primary amyloidosis, including 5 with Sjogren syndrome, 1 with rheumatoid arthritis, and 1 wit

24 ses were Stevens-Johnson syndrome (22 eyes), Sjogren syndrome (11 eyes), graft-vs-host disease (2 eye

25 2008 to May 2011, 120 patients with primary Sjogren syndrome according to American-European Consensu

26 scusses difficulties in diagnosing childhood Sjogren syndrome and highlights recent findings in Sjogr

27 mechanisms involved in the manifestations of Sjogren syndrome and rheumatoid arthritis.

28 rature include a dry eye syndrome similar to Sjogren syndrome, and ischemic retinopathy caused by eit

29 of important genetic modifiers of Marinesco-Sjogren syndrome, and provide additional pathways for th

30 risks for lung cancer, rheumatoid arthritis, Sjogren syndrome, and Raynaud syndrome.

31 duce de novo synthesis of LAMB1 protein in a Sjogren syndrome antigen B (La/SSB)-dependent manner in

32 al siRNA that targets endogenously expressed Sjogren syndrome antigen B (Ssb) mRNA, indicating that o

33 Here, we identify Sjogren syndrome antigen B (SSB)/La as a pre-miRNA-bindi

34 ineutrophil cvtoplasmic antibody (or cANCA), Sjogren syndrome antigens A and B (SS-A and SS-B, respec

35 s, the prevalence and prognosis of childhood Sjogren syndrome are unknown, in part due to lack of chi

36 e, we uncover a molecular mechanism by which Sjogren syndrome-associated autoantigen (SSA), an estrog

37 so found in the conjunctiva of patients with Sjogren syndrome at the gene and protein levels.

38 tear deficiency (ATD), Sjogren syndrome, non-Sjogren syndrome ATD, and control subjects.

39 ritis, systemic lupus erythematosus, primary Sjogren syndrome, autoimmune vesiculobullous skin diseas

40 ly higher incidence of rheumatoid arthritis, Sjogren syndrome, celiac disease, type I diabetes mellit

41 worse corneal epithelial disease in ATD and Sjogren syndrome, conditions with lacrimal gland dysfunc

42 y reduced in the tear fluid of patients with Sjogren syndrome, corroborating mRNA data obtained using

43 y (rheumatoid arthritis; lupus; scleroderma; Sjogren Syndrome; dermatomyositis/polymyositis; unspecif

44 n side effect of head and neck radiotherapy, Sjogren syndrome, diabetes, old age, and numerous medica

45 levated levels of IL-1beta, as they occur in Sjogren syndrome exocrine glands, may impair the secreto

46 m; P = .0057), ATD (210 mum; P = .0016), and Sjogren syndrome groups (171 mum; P = .0054).

47 il1 gene have been associated with Marinesco-Sjogren syndrome, hallmarks of which include ataxia and

48 The tear fluid of patients with Sjogren syndrome has reduced levels of the goblet cell-s

49 ative abundance of MUC mRNA in patients with Sjogren syndrome in relation to that of normal subjects.

50 seases like systemic lupus erythematosus and Sjogrens syndrome in humans.

51 Sjogren syndrome is a chronic autoimmune disease affecti

52 Childhood Sjogren syndrome is a poorly defined and underdiagnosed

53 Primary Sjogren syndrome is a systemic autoimmune disease charac

54 The pathogenesis of Sjogren syndrome is emerging, including roles of T and B

55 Although primary Sjogren syndrome is typically considered a disease of mi

56 IL-10 partially suppressed the appearance of Sjogren-syndrome-like features of reduced tear productio

57 ession was found in experimental dry eye and Sjogren syndrome models and was GC specific.

58 Marinesco-Sjogren syndrome (MSS) is an autosomal recessive, neurod

59 and mutations in this gene lead to Marinesco-Sjogren syndrome (MSS), a debilitating autosomal recessi

60 us erythematosus, antiphospholipid syndrome, Sjogren syndrome, myasthenia gravis, and celiac disease.

61 f normal subjects (n = 17) and patients with Sjogren syndrome (n = 11) after instillation of 60 micro

62 isease (MGD), aqueous tear deficiency (ATD), Sjogren syndrome, non-Sjogren syndrome ATD, and control

63 p = 0.003), Raynaud syndrome (p = 0.023) and Sjogren syndrome (p = 0.044) were significantly associat

64 Specific recent notable findings in Sjogren syndrome pathogenesis include identification of

65 Total of 163 consecutive primary Sjogren syndrome patients evaluated between January 2007

66 decreased in the conjunctival epithelium of Sjogren syndrome patients with dry eye and decreased gob

67 I interferon signature in salivary glands of Sjogren syndrome patients, characterization of salivary

68 Primary Sjogren syndrome (pSS) is an autoimmune disorder charact

69 e is involved in the pathogenesis of primary Sjogren syndrome (pSS), but whether the signature is typ

70 Systemic lupus erythematosus and Sjogren syndrome remain elusive in the description of th

71 ffects of intestinal dysbiosis in a model of Sjogren syndrome (SS) by subjecting mice to desiccating

72 neck cancers or from the autoimmune disease Sjogren syndrome (SS) frequently result in the reduction

73 e probes show prominent IFN-gamma effects in Sjogren syndrome (SS) tissues.

74 Sjogren syndrome (SS), the second most common autoimmune

75 cy [n = 10]-without (n = 7) and with (n = 3) Sjogren syndrome (SS)-and conjunctivochalasis [n = 12])

76 rma, thyroiditis, primary biliary cirrhosis, Sjogren syndrome, systemic lupus, dermatomyositis, and n

77 Among patients with primary Sjogren syndrome, the use of hydroxychloroquine compared

78 n syndrome and highlights recent findings in Sjogren syndrome treatment and pathogenesis from studies

79 the conjunctival epithelium of patients with Sjogren syndrome was significantly lower than in normal

80 implications for the human ataxia Marinesco-Sjogren syndrome, where it is interesting to speculate t

81 mab show some therapeutic potential in adult Sjogren syndrome, whereas newer modalities including gen