ライフサイエンスコーパス: T-cell antigen receptor

1 step for T cell activation triggered by the T cell antigen receptor.

2 le entry and responses to stimulation of the T cell antigen receptor.

3 pon weak recognition of self-antigens by the T cell antigen receptor.

4 ion of CD4+ T cells after stimulation of the T cell antigen receptor.

5 ignaling including that originating from the T cell antigen receptor.

6 Treg cells separable from signaling via the T cell antigen receptor.

7 s that are activated after engagement of the T cell antigen receptor.

8 olled by signaling pathways initiated by the T cell antigen receptor.

9 ation and effector functions mediated by the T-cell antigen receptor.

10 te development is shaped by signals from the T-cell antigen receptor.

11 ns in signalling complexes downstream of the T-cell antigen receptor.

12 g on the cellular mechanisms driven by B and T cell antigen receptors.

13 t evident in the enormous diversity of B and T cell antigen receptors.

14 gens, which bind to CD1 proteins and contact T cell antigen receptors.

15 ntigens) on the surface of other cells using T cell antigen receptors.

16 les, peptides presented by HLA molecules and T-cell antigen receptors.

17 gamma delta and the CD8 alpha alpha Thy1(-) T cell antigen receptor alpha beta IEL populations, depe

18 (J(alpha)) segments in the gene encoding the T cell antigen receptor alpha-chain (Tcra) and had a pro

19 In particular, c-Myc and pre-T-cell antigen receptor alpha (Ptcra) are dimerization-d

20 of Notch1 as well as Deltex1 (Dtx1) and pre T-cell antigen receptor alpha (Ptcra), two genes that ar

21 luding genes that activate expression of the T-cell antigen receptor alpha chain (TCR-alpha) in devel

22 double-negative thymocytes positive for the T cell antigen receptor alphabeta subtype (TCRalphabeta)

23 We identified Notch, the T cell antigen receptor and c-Myc as key controllers of

24 ed a role for the Akt kinase in coupling the T cell antigen receptor and CD28 to NF-kappaB activation

25 the six-chain assembly intermediate between T cell antigen receptor and the CD3delta epsilon and CD3

26 a is a critical mediator of signaling by the T cell antigen receptor and the principal costimulatory

27 lls is controlled by tonic signaling through T cell antigen receptors and common gamma chain cytokine

28 Akt is known to be activated by the T-cell antigen receptor and the cytokine IL-2, but its r

29 ing the balance of persistent stimulation of T-cell antigen receptors and specific CD2-induced co-sti

30 tigen-specific responses, such as CD4, CD28, T-cell antigen receptor, and class I and class II major

31 CD4 T cells from old mice incubated on anti-T cell antigen receptor antibodies with transforming gro

32 Abeta was significantly lower than with anti-T-cell antigen receptor antibodies (Abs).

33 e incubated on anti-CD3 plus anti-CD28 (anti-T cell antigen receptor) antibodies.

34 tion checkpoint without first expressing the T cell antigen receptor beta-chain (TCRbeta).

35 crodissection, transcriptional profiling and T-cell antigen receptor beta-chain (TCRbeta) genotyping

36 ors shaping their variable repertoire of the T-cell antigen receptor beta-chain, in addition to novel

37 ence for a fundamentally different basis for T cell antigen receptor-beta (Tcrb) allelic exclusion.

38 productive rearrangement of segments of the T cell antigen receptor-beta gene (Tcrb) and formation o

39 ifs to tyrosine kinases and may regulate the T-cell antigen receptor biological activities for this c

40 d these cells can be activated through their T cell antigen receptors by microbial lipid antigens.

41 he TM domains thus shows similarities to the T cell antigen receptor-CD3 complex, in particular to th

42 te deficiency of the CD3epsilon chain of the T cell antigen receptor/CD3 complex causes human SCID.

43 with human T-lymphotropic virus type 1; (ii) T cell antigen receptor clonotype repertoires; and (iii)

44 48-CD2 and CD48-CD22 induce an eccentric CD2/T cell antigen receptor cluster.

45 The role of the T cell antigen receptor complex (TCR) in alphabeta/gamma

46 ptor gene loci and not by the specificity of T-cell antigen receptor/coreceptor signalling.

47 T cell antigen receptor delta (Tcrd) variable region exo

48 that HAA inhibits NF-kappaB activation upon T cell antigen receptor engagement by specifically targe

49 (ESCRTs) at the plasma membrane to generate T-cell antigen receptor-enriched microvesicles.

50 e findings indicate that the affinity of the T cell antigen receptor for self antigen drives the diff

51 types require activation of NF-kappaB by the T cell antigen receptor for their generation, and the Nf

52 daptive immunity are the immunoglobulins and T-cell antigen receptors found in jawed vertebrates.

53 e-mediated migration, it was dispensable for T cell antigen receptor functions in T cells.

54 y, it was shown that Vitamin D modulates the T cell antigen receptor, further demonstrating that Vita

55 naling of naive T cells is restricted to the T cell antigen receptor, Fyn plays an essential role by

56 icularly CD8 alpha alpha Thy1(-)V gamma 5(+) T cell antigen receptor gamma delta and the CD8 alpha al

57 Here, we used T cell antigen receptor gene transfer to target CD4(+) T

58 of the immunological synapse sequesters the T cell antigen receptor in a location where it cannot in

59 r differences in the binding strength of the T cell antigen receptor in the antigen-specific mechanis

60 Activation of T cell antigen receptors induced expression of pro-IL-1b

61 oteolysis is therefore essential for optimal T cell antigen receptor-induced activation of NF-kappaB

62 The T-cell antigen receptor is an assembly of eight single-p

63 ity complex class II and the most restricted T cell antigen receptor junctional diversity 'preferenti

64 Signaling through the T cell antigen receptor leading to elimination (negative

65 Engagement of the T-cell antigen receptor leads to recruitment of phosphol

66 ered pMHC-II reveals the organization of the T cell antigen receptor ligand on the DC surface.

67 ted by the intermediate avidity of their own T cell antigen receptor-ligand interactions.

68 secrete IL-2, and proliferate in response to T cell antigen receptor ligation.

69 T cell antigen receptor-mediated activation of T cells t

70 apses are initiated by signaling in discrete T cell antigen receptor microclusters and are important

71 essary for complete assembly and movement of T cell antigen receptor microclusters.

72 dent spreading only after stimulation of the T-cell antigen receptor or the integrin alpha4beta1.

73 s a membrane-tethered IL13 cytokine chimeric T-cell antigen receptor, or zetakine.

74 e TNF receptor 1; cross-linking of the B- or T-cell antigen receptors; peptidoglycan, which activates

75 igh expression in thymocytes between the pre-T cell antigen receptor (pre-TCR) and positive-selection

76 Signaling via the pre-T cell antigen receptor (pre-TCR) and the receptor Notch

77 eckpoints consisting of the precursor to the T cell antigen receptor (pre-TCR) and the TCR.

78 T cell antigen receptor-proximal signaling components, R

79 A diverse T cell antigen receptor repertoire in progenitor-deprive

80 (TEC) is essential for generating a diverse T cell antigen receptor repertoire tolerant to self-anti

81 immunocompetent T cells with a self-tolerant T cell antigen receptor repertoire.

82 lerant CD4+ and CD8+ populations with normal T-cell antigen receptor repertoires, cytokine secretion

83 B or T cell lines stimulated through B- and T-cell antigen receptors, respectively.

84 Engagement of the T-cell antigen receptor results in a removal of Csk from

85 We find that components of T cell antigen receptor signal machinery and several key

86 ck binding region of SLP-76 is essential for T cell antigen receptor signaling and normal T cell deve

87 Thus, T cell antigen receptor signaling and the subsequent for

88 recently reported that YopH acutely inhibits T cell antigen receptor signaling by dephosphorylating t

89 The initiation of T cell antigen receptor signaling is a key step that can

90 An exception is the T cell antigen receptor signaling pathway, which bypasse

91 T cell antigen receptor signaling proteins, including ze

92 hymocyte positive selection by enhancing the T cell antigen receptor signaling response to low-affini

93 ed the tumor suppressor KLF4 'downstream' of T cell antigen receptor signaling to induce cell cycle a

94 , a cytoplasmic tyrosine kinase required for T cell antigen receptor signaling, is controlled by a re

95 Vitamin D and VDR are directly involved in T cell antigen receptor signaling.

96 -regulated kinase and T cells for subsequent T cell antigen receptor signaling.

97 roliferation stimulus commonly used to mimic T cell antigen receptor signaling.

98 We conclude that G3BP is a new player in T-cell-antigen receptor signaling and acts to reduce the

99 zeta (a signal-transduction component of the T-cell antigen receptor) signaling domains.

100 Interleukin 7 (IL-7) and T cell antigen receptor signals have been proposed to be

101 ls) following suboptimal stimulation via the T cell antigen receptor (TCR) (induced T(reg) cells (iT(

102 nstream responses of T lymphocytes following T cell antigen receptor (TCR) activation are mediated by

103 resented by CD1d, expression of an invariant T cell antigen receptor (TCR) alpha chain, and unusual r

104 The locus encoding the T cell antigen receptor (TCR) alpha-chain and delta-chai

105 lations further differed in their use of the T cell antigen receptor (TCR) alpha-chain variable regio

106 ain joining region 18 (V(alpha)14J(alpha)18) T cell antigen receptor (TCR) alpha-chain.

107 The interaction between the T cell antigen receptor (TCR) and antigenic peptide in c

108 ia acted in synergy with stimulation via the T cell antigen receptor (TCR) and coreceptor CD28 to acc

109 T cell antigen receptor (TCR) and coreceptor ligation is

110 We found that signaling via the T cell antigen receptor (TCR) and cytokine stimulation p

111 molecules associated with activation of the T cell antigen receptor (TCR) and of immunological-check

112 ceptor modulates the interaction between the T cell antigen receptor (TCR) and peptide-major histocom

113 The expression of Myc is regulated by the T cell antigen receptor (TCR) and pro-inflammatory cytok

114 ted directly with the signal strength of the T cell antigen receptor (TCR) and required the corecepto

115 own as protein kinase B, is activated by the T cell antigen receptor (TCR) and the cytokine interleuk

116 igh ITAM multiplicity) in the complex of the T cell antigen receptor (TCR) and the invariant signalin

117 We found that clonotypes expressing the T cell antigen receptor (TCR) beta-chain variable region

118 phosphatase PTPN22 limited signaling via the T cell antigen receptor (TCR) by weak agonists and self

119 Variable strengths of signaling via the T cell antigen receptor (TCR) can produce divergent outc

120 function correlates with genomically encoded T cell antigen receptor (TCR) chains, which suggests tha

121 This was associated with distinct T cell antigen receptor (TCR) clonotypes, characterized

122 we analyzed the spatio-temporal dynamics of T cell antigen receptor (TCR) complexes and linker for a

123 T cell antigen receptor (TCR) cross-linking initiates si

124 Interactions driven by the T cell antigen receptor (TCR) determine the lineage fate

125 complex (MHC) proteins are recognized by the T cell antigen receptor (TCR) dictates the homeostasis o

126 Engagement of the T cell antigen receptor (TCR) during antigen presentatio

127 In the thymus, low-affinity T cell antigen receptor (TCR) engagement facilitates pos

128 T cell antigen receptor (TCR) engagement has been shown

129 The interaction between the T cell antigen receptor (TCR) expressed by natural kille

130 types generally show simplified patterns of T cell antigen receptor (TCR) expression, rapid effector

131 Crystal structures of a T cell antigen receptor (TCR) from a MAIT cell in comple

132 Nonetheless, coengagement of T cell antigen receptor (TCR) gammadelta and CD46 suppre

133 It was previously shown that the Valpha14i T cell antigen receptor (TCR) has a high affinity for th

134 31 was strongly induced by activation of the T cell antigen receptor (TCR) in a pathway involving cal

135 roscopy to study complexes downstream of the T cell antigen receptor (TCR) in single-molecule detail

136 interleukin 17 (IL-17), but the role of the T cell antigen receptor (TCR) in this developmental proc

137 The delivery of signals from the activated T cell antigen receptor (TCR) inside the cell relies on

138 The T cell antigen receptor (TCR) is a multisubunit receptor

139 Although heightened signaling via the T cell antigen receptor (TCR) is critical for the differ

140 Signaling via the T cell antigen receptor (TCR) is initiated by Src-family

141 The T cell antigen receptor (TCR) is unique in that its affi

142 s) requires interleukin 2 (IL-2) and agonist T cell antigen receptor (TCR) ligands and is controlled

143 eton and impaired actin polymerization after T cell antigen receptor (TCR) ligation.

144 ing T cells, coreceptor choice is matched to T cell antigen receptor (TCR) MHC specificity during pos

145 RF) microscopy showed that signaling via the T cell antigen receptor (TCR) occurred during synapse tr

146 selection, which requires recognition by the T cell antigen receptor (TCR) of complexes of self pepti

147 The T cell antigen receptor (TCR) on the surface of T cells

148 How the T cell antigen receptor (TCR) recognizes these cations b

149 processes, but its role in signaling via the T cell antigen receptor (TCR) remains unknown.

150 ls) characterized by either a semi-invariant T cell antigen receptor (TCR) repertoire (type I NKT cel

151 er T cells (iNKT cells) express a restricted T cell antigen receptor (TCR) repertoire and they respon

152 actors and cell-intrinsic factors related to T cell antigen receptor (TCR) signal quantity and qualit

153 ning the nature of molecules involved in the T cell antigen receptor (TCR) signal transduction networ

154 le deficiencies in thymic development and in T cell antigen receptor (TCR) signal transduction, in PT

155 found that calcineurin was recruited to the T cell antigen receptor (TCR) signaling complex, where i

156 ytes transition through a stage during which T cell antigen receptor (TCR) signaling controls CD4-ver

157 T cell antigen receptor (TCR) signaling drives distinct

158 f CD8(+) T cells in the thymus requires that T cell antigen receptor (TCR) signaling end in time for

159 T cell antigen receptor (TCR) signaling in CD4(+)CD8(+)

160 genotype at CTLA4 is associated with altered T cell antigen receptor (TCR) signaling in naive and/or

161 to immunity and requires a limited degree of T cell antigen receptor (TCR) signaling in response to s

162 T cell antigen receptor (TCR) signaling in the thymus in

163 T cell antigen receptor (TCR) signaling is necessary but

164 lf-reactivity, with a particular emphasis on T cell antigen receptor (TCR) signaling thresholds.

165 the Carma1-Bcl10-MALT1 (CBM) complex couples T cell antigen receptor (TCR) signaling to IkappaB kinas

166 e catalytic activity of Zap70 is crucial for T cell antigen receptor (TCR) signaling, but the quantit

167 To investigate how Csk activity regulates T cell antigen receptor (TCR) signaling, we utilized a m

168 f which approximately 450 were controlled by T cell antigen receptor (TCR) signaling.

169 protein tyrosine kinase that is required for T cell antigen receptor (TCR) signaling.

170 olecular interactions, which are crucial for T cell antigen receptor (TCR) signaling.

171 a (Cbl) proteins are negative regulators for T cell antigen receptor (TCR) signaling.

172 ein of 76 kD (SLP-76), which are crucial for T cell antigen receptor (TCR) signaling.

173 activator of the RAS-MAPK pathway following T cell antigen receptor (TCR) signaling.

174 onobese diabetic (NOD) mice transgenic for a T cell antigen receptor (TCR) specific for one of the im

175 However, the function of T cell antigen receptor (TCR) specificity in thymic Treg

176 This activity was induced after T cell antigen receptor (TCR) stimulation and was indepe

177 y sensor of thresholds for signaling via the T cell antigen receptor (TCR) that was essential for T c

178 The ability of a single T cell antigen receptor (TCR) to cross-react with multip

179 Classically, signal transduction from the T cell antigen receptor (TCR) to ERK is thought to be re

180 owever, the mechanisms that allow the clonal T cell antigen receptor (TCR) to functionally engage mul

181 p1A and Foxp1D induced by stimulation of the T cell antigen receptor (TCR) to inhibit the generation

182 and the tyrosine phosphatase CD45 underpins T cell antigen receptor (TCR) triggering, but how such s

183 T cell proliferation is initiated by T cell antigen receptor (TCR) triggering, soluble growth

184 isplayed enhanced proximal signaling via the T cell antigen receptor (TCR) without an effect on the a

185 T cell antigen receptor (TCR) zeta was also identified a

186 In addition to ligation of the T cell antigen receptor (TCR), activation of the CD28 co

187 press an evolutionarily conserved, invariant T cell antigen receptor (TCR), but the forces that drive

188 cating THEMIS in signaling downstream of the T cell antigen receptor (TCR), but the mechanistic under

189 The alphabeta T cell antigen receptor (TCR), in complex with the CD3de

190 When T cells encounter antigens via the T cell antigen receptor (TCR), information about the qua

191 Upon recognition of antigen by the T cell antigen receptor (TCR), roquin and regnase-1 prot

192 By single-cell photoactivation of the T cell antigen receptor (TCR), we found that three disti

193 in T cells in response to engagement of the T cell antigen receptor (TCR), which induced expression

194 The T cell antigen receptor (TCR)-CD3 complex is unique in h

195 e activation of specific T cells through the T cell antigen receptor (TCR)-CD3 complex.

196 lated from tissues of Ctla4(-/-) mice showed T cell antigen receptor (TCR)-dependent accumulation in

197 Thus, BATF amplifies T cell antigen receptor (TCR)-dependent expression of tr

198 We found that T cell antigen receptor (TCR)-driven signaling initially

199 Inhibition of T cell antigen receptor (TCR)-driven stop signals depend

200 chanistically, we demonstrate a link between T cell antigen receptor (TCR)-induced asymmetric express

201 e-operated Ca(2+) channel and contributed to T cell antigen receptor (TCR)-induced Ca(2+) influx, TCR

202 ular signaling molecule that is required for T cell antigen receptor (TCR)-induced cytokine synthesis

203 d immunodeficiency syndrome due to defective T cell antigen receptor (TCR)-induced NF-kappaB signalin

204 T cell antigen receptor (TCR)-induced signals to activat

205 cell-activating NKG2D-DAP10 complex and the T cell antigen receptor (TCR)-invariant signaling protei

206 -forming subunit Ca(v)1.4 and attenuation of T cell antigen receptor (TCR)-mediated global Ca(2+) ent

207 lular adhesion molecules (ICAMs) facilitates T cell antigen receptor (TCR)-mediated killing.

208 The T cell antigen receptor (TCR)-peptide-major histocompati

209 re, we have adopted a procedure developed in T cell antigen receptor (TCR)-transgenic mice to convert

210 ssing aberrant proliferation mediated by the T cell antigen receptor (TCR).

211 n T cells was regulated by pathogens and the T cell antigen receptor (TCR).

212 naling via both interleukin 7 (IL-7) and the T cell antigen receptor (TCR).

213 ant role for Zap70 in signals induced by the T cell antigen receptor (TCR).

214 munology article to describe features of the T cell antigen receptor (TCR).

215 T cell effector functions require the T cell antigen receptor (TCR).

216 h cell proliferation and stimulation via the T cell antigen receptor (TCR).

217 ntigen-presenting molecules by the alphabeta T cell antigen receptor (TCR).

218 rnative activation pathway downstream of the T cell antigen receptor (TCR).

219 -inducible interaction between ZAP70 and the T cell antigen receptor (TCR)/CD3 complex.

220 T cell antigen receptor (TCR)beta V(D)J variable region

221 Lck to generate T cells expressing alphabeta T cell antigen receptors (TCR).

222 In mice that express a transgene for the 2C T cell antigen-receptor (TCR) and lack a recombinase-act

223 blocked effector T-cell proliferation after T cell-antigen receptor (TCR) engagement, but had no sig

224 s recruited to the immunologic synapse after T cell-antigen receptor (TCR) stimulation.

225 The T-cell antigen receptor (TCR) alpha-chain (TCRalpha) is

226 They have an invariant T-cell antigen receptor (TCR) alpha-chain, but whether t

227 Signals through the T-cell antigen receptor (TCR) and interleukin-2 (IL-2) p

228 organization of CD4, and its relationship to T-cell antigen receptor (TCR) and the active form of Src

229 ssed rearrangements of the gene encoding the T-cell antigen receptor (TCR) beta chain.

230 The T-cell antigen receptor (TCR) complex contains 10 copies

231 CD3zeta is a subunit of the T-cell antigen receptor (TCR) complex required for its a

232 The T-cell antigen receptor (TCR) exists in monomeric and na

233 The T-cell antigen receptor (TCR) is an assembly of eight ty

234 The self-reactivity of their T-cell antigen receptor (TCR) is thought to contribute t

235 y upregulated in murine T cells activated by T-cell antigen receptor (TCR) ligation and CD28 costimul

236 lts in aberrant activation of NF-kappaB upon T-cell antigen receptor (TCR) ligation, which is mediate

237 e use phage display to isolate and enhance a T-cell antigen receptor (TCR) originating from a CTL lin

238 Strikingly, the mutation attenuates T-cell antigen receptor (TCR) proximal signaling, includ

239 The semi-invariant MAIT T-cell antigen receptor (TCR) recognises riboflavin and

240 Here we show that the T-cell antigen receptor (TCR) repertoire of intestinal T

241 f RNA-seq for assessing T-cell clonality and T-cell antigen receptor (TCR) repertoire of the neoplast

242 Engagement of the T-cell antigen receptor (TCR) results in the proximal ac

243 T-cell antigen receptor (TCR) signaling is essential for

244 through plasma membrane domains that form at T-cell antigen receptor (TCR) signalling foci.

245 T-cell antigen receptor (TCR) signalling results in the

246 toire requires appropriate interpretation of T-cell antigen receptor (TCR) signals by CD4(+ ) CD8(+)

247 Mutations in T-cell antigen receptor (TCR) subunit genes cause rare i

248 e (PTK), is required to couple the activated T-cell antigen receptor (TCR) to downstream signaling pa

249 The binding of a T-cell antigen receptor (TCR) to peptide antigen present

250 We demonstrate that upon ligation of the T-cell antigen receptor (TCR), the TCR associates with a

251 ls that develop in these mice have defective T-cell antigen receptor (TCR)-induced calcium flux but e

252 an essential mediator of signaling from the T-cell antigen receptor (TCR).

253 ion pathways, including that mediated by the T-cell antigen receptor (TCR).

254 Whether T-cell antigen receptors (TCR) on donor T cells require

255 ires are biased toward particular gammadelta T cell antigen receptors (TCRs) according to location.

256 responses are driven by interactions between T cell antigen receptors (TCRs) and complexes of peptide

257 t of innate CD8(+) T cells that have diverse T cell antigen receptors (TCRs) but have a memory phenot

258 In mice, iNKT cells express T cell antigen receptors (TCRs) comprising a unique TCRa

259 It remains unclear whether gammadelta T cell antigen receptors (TCRs) detect antigens in a way

260 quence of intrathymic selection during which T cell antigen receptors (TCRs) expressed by immature th

261 und molecules are subsequently recognized by T cell antigen receptors (TCRs) expressed on the surface

262 T cells bearing gammadelta T cell antigen receptors (TCRs) function in lymphoid str

263 Signals transduced by T cell antigen receptors (TCRs) have been shown to be cr

264 Studies of individual T cell antigen receptors (TCRs) have shed some light on

265 question is whether an altered repertoire of T cell antigen receptors (TCRs) is associated with such

266 II-restricted self antigens by autoreactive T cell antigen receptors (TCRs) is established, but how

267 Human T cell antigen receptors (TCRs) pair in millions of comb

268 liferation of naive T lymphocytes expressing T cell antigen receptors (TCRs) specific for foreign pep

269 the virus activated T cells expressing dual T cell antigen receptors (TCRs) that were able to recogn

270 The binding of T cell antigen receptors (TCRs) to specific complexes of

271 e-positive (DP)) thymocytes are signaled via T cell antigen receptors (TCRs) to undergo positive sele

272 Interactions of T cell antigen receptors (TCRs) with complexes of self p

273 ve selection is based on the interactions of T cell antigen receptors (TCRs) with self peptide-major

274 respond rapidly to stress despite expressing T cell antigen receptors (TCRs), a hallmark of adaptive

275 release for Zap70 kinases at phosphorylated T cell antigen receptors (TCRs).

276 1a-autoreactive repertoire contained diverse T cell antigen receptors (TCRs).

277 mpatibility complex (MHC) class I-restricted T cell antigen receptors (TCRs).

278 nnate response is dependent on IL-33 but not T cell antigen receptors (TCRs).

279 red through surface molecules, including the T-cell antigen receptors (TcRs) and cytokine receptors.

280 It is driven by specific T-cell antigen receptors (TCRs) binding to antigenic pep

281 We observed that colonic T(reg) cells used T-cell antigen receptors (TCRs) different from those use

282 clones is diverse and contains cells bearing T-cell antigen receptors (TCRs) that differ in their aff

283 The interaction of alphabeta T-cell antigen receptors (TCRs) with peptides bound to M

284 rescence, and next-generation sequencing for T-cell antigen receptors (TCRs).

285 checkpoint inhibition, mAbs, and engineered T-cell antigen receptors, the incidence and pattern of m

286 rates generate a diverse repertoire of B and T cell antigen receptors through the rearrangement of im

287 s that mediate inside-out signaling from the T cell antigen receptor to integrins, giving rise to inc

288 The data demonstrate in vivo synergy between T cell antigen receptor-transduced CD4(+) and CD8(+) T c

289 expression, which expression of a rearranged T cell antigen receptor transgene cannot rescue.

290 or frequency of adoptively transferred naive T cell antigen receptor transgenic CD4 T cells.

291 recognition of beta-GlcCer by the invariant T cell antigen receptor translates innate danger signals

292 show that T cell activation mediated by the T cell antigen receptor translocates plasma membrane S1P

293 (LAT) is a critical signaling hub connecting T cell antigen receptor triggering to downstream T cell

294 onors display altered alpha3135-145-specific T-cell antigen receptor usage, HLA-DR15-alpha3135-145 te

295 T cells, enriched for self antigen-specific T cell antigen receptors, was also present in healthy ho

296 By single-cell photoactivation of the T cell antigen receptor, we show that MTOC polarization

297 solvent-exposed and therefore accessible to T-cell antigen receptors were predicted to be immunogeni

298 nhanced responses to weak stimulation of the T cell antigen receptor, when transferred into lymphopen

299 Phorbol esters or the engagement of the T cell antigen receptor, which activate PKC and the expr

300 n important class of immune receptors (e.g., T-cell antigen receptors) whose ligands are anchored to