ライフサイエンスコーパス: T-cell epitope

1 J8 does not contain a dominant GAS-specific T cell epitope.

2 the Mamu-A1*00101-bound Gag(181-189)CM9 CD8+ T cell epitope.

3 ing high levels of the I-E(k)-restricted hLa T cell epitope.

4 o include the most common forms of potential T cell epitopes.

5 lly determined and computer-predicted CD4(+) T cell epitopes.

6 hampered by the lack of defined RSV-specific T cell epitopes.

7 atrix for identification of disease-relevant T cell epitopes.

8 d to identify novel RSV-specific CD4 and CD8 T cell epitopes.

9 s but contains conserved, immunodominant CD8 T cell epitopes.

10 he efficient identification of MiHA or other T cell epitopes.

11 to the developing prediction algorithms for T cell epitopes.

12 onses from 30 allergic donors, identified 25 T cell epitopes.

13 roduction of numerous MHC class I-restricted T cell epitopes.

14 ive survey to date of human allergen-derived T cell epitopes.

15 nors, resulting in the identification of 257 T cell epitopes.

16 prediction method for the identification of T cell epitopes.

17 in C-peptide as an abundant source of CD8(+) T cell epitopes.

18 T cell reactivity revealed a large number of T cell epitopes.

19 y processed ligands, cancer neoantigens, and T cell epitopes.

20 roves comprehensive identification of CD8(+) T cell epitopes.

21 ly directed against immunodominant conserved T cell epitopes.

22 ability to sensitize and is devoid of major T-cell epitopes.

23 des, defining a large number of discrete CD4 T-cell epitopes.

24 been speculation that H7N9 will have few CD4 T-cell epitopes.

25 -A2-, HLA-B0702-, and HLA-B08-restricted CD8 T-cell epitopes.

26 Like Api g 1, Mal d 1 lacked dominant T-cell epitopes.

27 nal approach to test for selection in CD8(+) T-cell epitopes.

28 tion of novel, pathophysiologically relevant T-cell epitopes.

29 p120 enhanced responses to the dominant CD4+ T-cell epitopes.

30 ong DR04:01 restricted Pooideae grass-pollen T-cell epitopes.

31 ype and function, and TCR reactivity to many T-cell epitopes.

32 confirmed that mutant peptides can serve as T-cell epitopes.

33 phenotype and recognized a broad variety of T-cell epitopes.

34 were immunized with a pool of virus-derived T-cell epitopes.

35 ted to distinct targeting of critical CD8(+) T-cell epitopes.

36 d not respond to the common DQ2.5-restricted T-cell epitopes.

37 mpatibility complex class I and II-presented T-cell epitopes.

38 as they can be fashioned to be free of viral T-cell epitopes.

39 ion and the clinical relevance of identified T-cell epitopes.

40 rrelates with the presence of immunodominant T-cell epitopes.

41 n cases of allergens in which the identified T cell epitopes accounted for a minor fraction of the ex

42 omprehensive identification of unique CD4(+) T-cell epitopes across the 4 DENV serotypes allows the t

43 wild-type variants for coverage of putative T-cell epitopes across the 9383 sequences in our dataset

44 onses were generated against known reference T cell epitopes after either peptide or DNA immunization

45 Eleven CD4(+) T cell epitopes, all but one derived from abundant virio

46 monstrate that the HLA-DRB1*15:01-restricted T cell epitope alpha3136-146 can induce T cell responses

47 ed a HLA-DRB1*15:01-restricted alpha3(IV)NC1 T cell epitope (alpha3136-146) with four critical residu

48 Three previously identified dominant T cell epitopes (Amb a 1 176-191, 200-215, and 344-359)

49 g allergen predictions, prediction of linear T cell epitopes and functional conformational epitopes,

50 of HLA class II restriction across multiple T cell epitopes and HLA types.

51 a), engineered to express several autologous T cell epitopes and sequences derived from the circumspo

52 Yet, cashew-specific T cell epitopes and T cell cross-reactivity amongst cash

53 amino acids encompassed by both antibody and T cell epitopes and were central to globally circulating

54 equence epitope previously identified as CD8 T-cell epitope and a second epitope that we previously i

55 These studies identify an immunodominant MPO T-cell epitope and redefine how effector responses can i

56 the mosaic method chooses the most frequent T-cell epitopes and combines them to form a synthetic an

57 with the human genome, the links between the T-cell epitopes and low immunogenicity of H7 HA remains

58 e antibodies bind gluten peptides related to T-cell epitopes and many have higher reactivity to deami

59 ogenicity by eliminating known and predicted T-cell epitopes and maximizing the content of human pept

60 The new immunotoxin has a 93% decrease in T-cell epitopes and should have improved efficacy in pat

61 orphic regions of FVIII constitute potential T-cell epitopes and thus could explain the increased inc

62 ffinity is widely used to identify candidate T cell epitopes, and an affinity of 500 nM is routinely

63 trol, with three Mamu-B*08-restricted CD8(+) T-cell epitopes, and demonstrate that these vaccinated a

64 of the murine mAb to remove predicted human T-cell epitopes, and the variable regions joined to huma

65 largely by the targeting of specific CD8(+) T-cell epitopes, and we identify eight epitopes that are

66 CD8 T cell memory in a mouse model where CD8 T cell epitopes are clearly defined.

67 e CD4 and CD8 T cell responses, whereas DENV T cell epitopes are found primarily in nonstructural pro

68 Mutations in T cell epitopes are implicated in hepatitis C virus (HCV

69 However, T-cell epitopes are difficult to identify and predict.

70 Allergen-specific T-cell epitopes are obvious targets for immunotherapeuti

71 at recognized these minimally cross-reactive T-cell epitopes are present in Grass-pollen-allergic sub

72 Some identified T-cell epitopes are promiscuous and recognizable by the

73 these data identify for the first time a Tg T cell epitope as a spontaneous target in ISAT.

74 DeltaAsn/Asp) and its conserved, immunogenic T cell epitopes as a fusion partner for protective domai

75 Definitive identification of pathogenic T cell epitopes as is now known in celiac disease and re

76 y to Ovm, and validated potential use of Ovm T-cell epitope as an immunoregulator.

77 This technique identified novel CD4(+) T-cell epitopes as well as a novel B-cell epitope, Meu10

78 ptide of Phl p 1 devoid of allergen-specific T cell epitopes, as recognized by BALB/c mice, was fused

79 The TYKW mutant retained T-cell epitopes, as evident from its lymphoproliferative

80 ied a class of hidden self-antigens known as T cell epitopes associated with impaired peptide process

81 n shown that MHC-Ilo tumors produce a set of T cell epitopes associated with impaired peptide process

82 T cell epitopes associated with impaired peptide process

83 T cell epitope-based oral immunotherapy is effective in

84 articular interest are mutated tumor antigen T-cell epitopes, because neoepitope-specific T cells oft

85 However, immunization with the CD4(+) T cell epitopes before infection resulted in significant

86 tides predicted to contain I-A(b)-restricted T-cell epitopes but not identified in WT mice.

87 A-associated mutations within or adjacent to T cell epitopes, but the potential impact of most mutati

88 nt on presentation of both CD4(+) and CD8(+) T cell epitopes by the same dendritic cell population.

89 ntly recognize a nonameric HLA-A2-restricted T-cell epitope called PR1 which is conserved in both Ags

90 However, it is unclear whether key T cell epitopes can be processed and presented from thes

91 Polymorphism of immunodominant CD8(+) T cell epitopes can facilitate escape from immune recogn

92 lso incorporating molecular adjuvant and CD4 T cell epitope cargo.

93 in macaques should be prioritized for CD8(+) T cell epitope characterization.

94 of the T cell response to Midkine relies on T cell epitopes contained in its signal peptide.

95 After identification of T cell epitope-containing parts on each of the 3 parenta

96 ergen Bet v 1 and recombinant hypoallergenic T-cell epitope-containing Bet v 1 fragments in patients

97 taneously optimize proteins for both reduced T cell epitope content and high-level function.

98 were able to identify a MHCII-restricted CD4 T cell epitope, corresponding to amino acids 37-47 in th

99 Here, we overcome a lack of T cell epitope data to construct swine epitope predictor

100 rcumsporozoite protein (CSP)-specific CD8(+) T cell epitope demonstrated that approximately two-third

101 ss allergen peptides, comprising 7 synthetic T-cell epitopes derived from Cyn d 1, Lol p 5, Dac g 5,

102 nstructive, but limited understanding of CD4 T cell epitope/determinant hierarchies hampers the ratio

103 cell lines for identifying CD8(+) and CD4(+) T-cell epitopes, determining the ability of vaccine-indu

104 the consensus sequence in the corresponding T-cell epitope did not expand in vitro.

105 Q-MS will not only find broad application in T-cell epitope discovery but also inform vaccine design

106 Traditional methods of T-cell epitope discovery use overlapping short peptides

107 These findings suggest that T cell epitope diversity may not be such a daunting prob

108 development of immunogens to overcome HIV-1 T-cell epitope diversity, identification of correlates o

109 Seven of the CD4(+) T cell epitopes do not share significant homologies with

110 Helper T-cell epitope dominance in human immunodeficiency virus

111 ducing non-sense mutations may still present T cell epitopes downstream of the premature termination

112 ction, and a large number of M. tuberculosis T cell epitopes enabled us to identify pMHC ligands for

113 ory T cells and identify a novel HLA-DR7/ HY T cell epitope, encoded by RPS4Y, a potential new therap

114 ny of compensatory mutations that allow CD8+ T cell epitope escape in infected individuals.

115 rns of linked mutations associated with CD8+ T cell epitope escape in these highly conserved regions

116 ch consists of screening for likely dominant T-cell epitopes, establishing antigen-specific memory T-

117 , even in human influenza virus NP, sites in T-cell epitopes evolve more slowly than do nonepitope si

118 import of the OVA peptide SIINFEKL, a CD8(+) T cell epitope frequently used to study cross-presentati

119 the first time, to our knowledge, a natural T cell epitope from Candida albicans.

120 (MCMV) recombinants expressing a single CD8 T cell epitope from HSV-1 fused to different MCMV genes,

121 or N terminus (B-T MAP) with a heterologous T cell epitope from Plasmodium falciparum.

122 Surprisingly, a well-characterized T cell epitope from the flagellar protein FliC afforded

123 We were able to identify T cell epitopes from 9 out of the 10 DENV proteins.

124 tability in the presence of DM distinguishes T cell epitopes from nonrecognized peptides in A10L pept

125 red the in silico HLA binding promiscuity of T cell epitopes from pathogens with distinct infection s

126 y 10 potential HLA-A*02:01-restricted CD8(+) T cell epitopes from the 718-aa sequence of VP11/12.

127 y 10 potential HLA-A*02:01-restricted CD8(+) T cell epitopes from the HSV-1 gB amino acid sequence.

128 This is the second HLA-B27-restricted T-cell epitope from C. trachomatis with relevance in ReA

129 chimeric peptide composed of a cytotoxic CD8 T-cell epitope from CMV pp65 and a tetanus T-helper epit

130 anoparticles (NPs) to coadminister ITE and a T-cell epitope from myelin oligodendrocyte glycoprotein

131 vaccine that is selectively based on CD8(+) T-cell epitopes from ASYMP individuals.

132 d 10 potential HLA-A*02:01-restricted CD8(+) T-cell epitopes from the 693-amino-acid sequence of the

133 r antigen-1 (EBNA1) fused to multiple CD8(+) T-cell epitopes from the EBV latent membrane proteins, L

134 inker-optimized peptide library of known CD8 T-cell epitopes from the mouse gamma-herpes virus 68.

135 T-cell epitopes from timothy grass (Phleum pratense) wer

136 he HLA A*0201 pp65(495-503) cytotoxic CD8(+) T-cell epitope fused to 2 different universal T-helper e

137 B) contains a strongly immunodominant CD8(+) T cell epitope (gB(498-505)) that is recognized by 50% o

138 cine express the immunodominant HSV-2 CD8(+) T cell epitope (gB(498-505)), and both were delivered in

139 d on MSP1 (PvRMC-MSP1) that includes defined T cell epitopes genetically fused to PvMSP119.

140 The USA-specific vaccine comprised 6 CD8+ T cell epitopes (GILGFVFTL, FMYSDFHFI, GMDPRMCSL, SVKEKD

141 Naturally processed T cell epitopes have been discovered by elution from HLA

142 cently described, so far no PVM-specific CD4 T cell epitopes have been identified within the C57BL/6

143 rast, studies identifying virus-specific CD4 T cell epitopes have indicated that CD4 T cells often re

144 Although multiple AQP4 T-cell epitopes have been identified in WT C57BL/6 mice,

145 es have previously been employed to identify T cell epitopes having important relevance to the human

146 lgorithms and provide new clues to improving T-cell epitope identification.

147 A pool of the most dominant T cell epitopes identified in the present study and from

148 bile dipeptide linker at the N terminus of a T-cell epitope improves proteasome-dependent class I MHC

149 e important contribution of this H7-specific T cell epitope in determining the immunogenicity of an i

150 Here, we describe a human CD4(+) T cell epitope in the influenza virus HA that lies in th

151 peptides were shown to encompass strong CD4 T cell epitopes in B. pseudomallei-exposed individuals a

152 Of 376 predicted HSV-1 CD8(+) T cell epitopes in C57BL/6 mice, 19 (gB(498-505) and 18

153 ass II alleles for immunodominant Gag CD4(+) T cell epitopes in clade C virus infection, constructed

154 Ags express major clade B and clade C viral T cell epitopes in human cells, as well as support the e

155 nd present major HIV clade B and clade C CD8 T cell epitopes in human cells.

156 e molecular determinants of allergen-derived T cell epitopes in humans utilizing the Phleum pratense

157 Most vaccines and basic studies of T cell epitopes in Mycobacterium tuberculosis emphasize

158 DR and -DQ loci accurately predicted Ara h 2 T cell epitopes in peanut-allergic subjects, suggesting

159 reg cells recognizing two virus-specific CD4 T cell epitopes in the coronavirus-infected central nerv

160 reakthrough viruses, we identified potential T cell epitopes in the founder sequences and compared th

161 VIII using, as input, the number of putative T cell epitopes in the infused protein and the competenc

162 affecting presentation of the immunodominant T-cell epitope in vitro.

163 To eliminate widespread T-cell epitopes in any biotherapeutic and thereby mitiga

164 human donors are identifying immunodominant T-cell epitopes in FVIII and possible targets for tolero

165 genicity reduction, and we use it to disrupt T-cell epitopes in GFP and Pseudomonas exotoxin A withou

166 h prior immunoinformatic analysis identified T-cell epitopes in H7 hemagglutinin (HA) which potential

167 h was used to identify HLA-restricted CD4(+) T-cell epitopes in Jug r 2.

168 ent of substitutions that alter human CD8(+) T-cell epitopes in NP of human versus swine influenza vi

169 ed the diversity of CS haplotypes across the T-cell epitopes in parasites from Lilongwe, Malawi.

170 sing human cells, we identified eight helper T-cell epitopes in PE38, a portion of the bacterial prot

171 teins, we adopted an assay to map the CD4(+) T-cell epitopes in PE38.

172 Identification of potential T-cell epitopes in the peanut major allergens is essenti

173 n plays a critical role in the generation of T-cell epitopes in type 1 diabetes.

174 We identified 5 new CD4 and 5 new CD8 T cell epitopes, including a CD8 T cell epitope within t

175 upport the possibility of incorporating FliC T cell epitopes into vaccination programs targeting both

176 The T cell epitope is naturally processed from alpha3(IV)NC1

177 ze the presentation of carbohydrate-specific T cell epitopes is 50-100 times more potent and substant

178 onditional; the accumulation of mutations in T cell epitopes is limited, and the rate of accumulation

179 However, identifying tumor-specific T-cell epitopes is a major challenge.

180 uantitate the immunodominant K(d)-restricted T-cell epitope islet-specific glucose-6-phosphatase cata

181 es and controls allergic inflammation at the T-cell epitope level is critical for the design of new a

182 T cell epitopes localized to conserved molecular regions

183 ptide representing immunodominant RSV CD8(+) T cell epitope M282-90, a TLR agonist (polyinosinic-poly

184 peptides of islet autoantigens as candidate T cell epitopes, many of which selectively bind to the H

185 Interestingly, polymorphic T-cell epitopes map to specialized alphaTSR regions.

186 Of note, 50% (5/10) of CD8(+) T cell epitopes mapped within the gamma-gliadins.

187 ted T cells were determined by a novel CD154 T cell epitope mapping assay.

188 T cell epitope mapping of Art v 6 revealed that it conta

189 T cell epitope mapping strategies increasingly rely on a

190 T cell epitope mapping studies using IFN-gamma ELISPOT w

191 T cell epitope mapping unveiled a 13-residue sequence co

192 promoter, the polypeptide context of a CD8(+)T cell epitope may determine whether classical or inflat

193 , we identified an immunodominant MPO CD4(+) T-cell epitope (MPO(409-428)).

194 several cross-specific MHC class I specific T cell epitopes naturally presented by influenza A-infec

195 pecific, cluster of differentiation (CD)8(+) T-cell epitope, nonstructural protein (NS)5B(2841-2849)

196 ion induced by the treatment of oligomerized T cell epitope of myelin proteolipid protein (PLP139-151

197 Thus, sequence homology between T cell epitopes of 2 self-proteins and a related order o

198 Identifying T cell epitopes of islet autoantigens is important for u

199 Two vaccines expressing CD4(+) and CD8(+) T cell epitopes of melanoma-associated Ags (MAAs) by a c

200 T cell epitopes of Met e 1 were first identified based o

201 on and optimization of HLA-restricted CD8(+) T cell epitopes of potential interest in various autoimm

202 ) T cells that target RV is largely unknown, T cell epitopes of RV capsid proteins were analyzed, and

203 ingle protein which contained immunodominant T cell epitopes of the three polypeptides.

204 We sought to identify the immunodominant T cell epitopes of tropomyosin, the major shrimp allerge

205 re we demonstrate that the expression of CD8 T-cell epitope of Listeria monocytogenes by a recombinan

206 ssing and MHC protein binding for all helper T-cell epitopes of an antigen.

207 We analyzed the T-cell epitopes of Mal d 1, the nonsensitizing Bet v 1 h

208 e defined the immunodominant, HLA-restricted T-cell epitopes of OprF.

209 bstitutions within computationally predicted T-cell epitopes--of which four were nonconservative--whi

210 viruses due to recognition of cross-reactive T cell epitopes, often from internal viral proteins cons

211 neration and presentation of APOBEC3-derived T cell epitopes on the surfaces of lentivirus-infected c

212 ects of the incorporation and arrangement of T-cell epitopes on antibody recognition.

213 the previously identified thyroglobulin (Tg) T cell epitope p2549-2560 containing thyroxine at positi

214 ognize an HLA-A*0201-presented wild-type p53 T-cell epitope, p5365-73(RMPEAAPPV).

215 A CD8(+) T cell epitope peptide from OVA (CSIINFEKL) and CpG were

216 Mice treated with the T cell epitope peptide mixture demonstrated an ameliorat

217 Known gluten T cell epitope peptides were enriched by DQ2.5, whereas

218 T-cell epitope peptides given orally may provide a pract

219 y investigates oral immunotherapy (OIT) with T-cell epitope peptides of the dominant egg-white allerg

220 MHC-class II-based T cell epitope prediction algorithms for HLA-DR and -DQ

221 T cell epitope prediction tools and associated vaccine d

222 ata shows significant promise for developing T cell epitope prediction tools for pigs.

223 a new generation of peptide:MHC binding and T-cell epitope predictive tools have been added.

224 Our data demonstrate that CD4(+) T cell epitopes present in the signal peptide can be acc

225 eptibility factor for many diseases, culprit T cell epitopes presented by disease-associated MHC mole

226 collagen, alpha3(IV)NC1, but critical early T cell epitopes presented by this human MHC class II mol

227 FVIII peptide regions that contained CD4(+) T-cell epitopes presented by HLA-DRB1*1501 to CD4(+) T c

228 nes that deliver different CD8(+) and CD4(+) T-cell epitopes presented by MHC class I and class II al

229 ated with Lyme arthritis (LA), we identified T-cell epitopes presented in vivo by human leukocyte ant

230 fections by detecting MHC class I restricted T-cell epitopes presented on infected cells.

231 Our approach uses fundamental insights into T cell epitope processing and presentation to define tar

232 ope diversities exhibit equivalent levels of T cell epitope promiscuity.

233 gning vaccine antigens to optimize potential T-cell epitope (PTE) coverage.

234 ries only in C-terminal truncation of the p6 T cell epitope, raising the possibility of selection by

235 ammed to achieve distinct patterns of CD8(+) T cell epitope recognition.

236 ntify B. melitensis MHC-II-restricted CD4(+) T cell epitopes recognized by the human immune response,

237 We conclude that PR2 represents a functional T-cell epitope recognized in mice and human leukemia pat

238 station in the retina as part of the CNS and T-cell epitopes recognized by the allogeneic T cells wer

239 ector prime boosting increased the number of T-cell epitopes recognized.

240 Several distinct T-cell epitope regions along the allergen were identifie

241 Mutations within T cell epitopes represent a common mechanism of viral es

242 xperiments, they contained allergen-specific T cell epitopes required for tolerance induction, and up

243 ected by mucoid PA, and they showed a narrow T-cell epitope response and a relative reduction in Th1

244 orm of brain cancer generates an immunogenic T cell epitope restricted by a common HLA subtype, there

245 In total, 15 PVM-specific CD8(+) T-cell epitopes restricted by H-2D(b) and/or H-2K(b) wer

246 Here we define HLA-restricted CD4(+) T-cell epitopes resulting from natural infection with de

247 hat is a homolog of a highly immunogenic EBV T cell epitope (SELEIKRY) presented by HLA-B*18:01.

248 bserved for IgE reactivity and influenced by T cell epitope sequence conservation.

249 Some T-cell epitope sequences in EBNA3 genes show extensive v

250 ant virus population within samples harbored T-cell epitopes similar to the reference BKV strain that

251 zed to Ovm and subsequently administered Ovm T-cell epitopes [single peptide 157-171 (SP) or multiple

252 Some T cell epitopes, such as p6, are able to bind diverse HL

253 ts with a polymorphic region overlapping two T cell epitopes, suggesting that variability in C-PfCSP

254 190A) are localized in class I/II-restricted T-cell epitopes, suggesting a role in HBV escape from T-

255 ined mutations occurred at sites enriched in T-cell epitopes, suggesting they promote viral immune es

256 ated this question in nonpermissive HLA-DPB1 T-cell epitope (TCE) mismatches reflected by numerical f

257 Our results indicate that CD4 T cell epitopes that are 17 amino acids in length result

258 arget conserved influenza virus antibody and T cell epitopes that do not vary from strain to strain.

259 e observations: 1) SERCA2a contains multiple T cell epitopes that induce varying degrees of myocardit

260 nsively studied in mice, no recognized human T cell epitopes that might provide new approaches to cla

261 ity of NetMHCpan to predict antiviral CD8(+) T cell epitopes that we identified with a traditional ap

262 synthesized and evaluated candidate mutated T cell epitopes that were identified using a major histo

263 were identified as minimally cross-reactive T-cell epitopes that do not show cross-reactivity to Phl

264 BV reproducibly selects substitutions in CD8 T-cell epitopes that functionally act as immune escape m

265 We identified a set of "type 2" T-cell epitopes that were recognized at 10-fold-lower le

266 Therefore, in the quest for T cell epitopes, the prediction of peptide binding to MH

267 E14 can be converted into a highly antigenic T-cell epitope through treatment with the enzyme transgl

268 alone and also linked with the measles virus T cell epitope to produce a chimeric peptide vaccine.

269 en studied, in part due to the lack of known T cell epitopes to vaccine viruses.

270 d with iterative computational prediction of T-cell epitopes to achieve extensive reengineering of a

271 dered to be mediated only by allergen B- and T-cell epitopes to promote allergen-specific IgE product

272 All T cell epitopes utilized mapped within rPfMSP8(DeltaAsn/

273 In addition, CD4 T cell epitope vaccination of immunocompetent mice reduc

274 that constitutively secretes a viral CD8(+) T-cell epitope via the Shigella type III secretion syste

275 ve panel of 467 HLA-A*0201-restricted CD8(+) T cell epitopes was predicted from the entire HSV-1 geno

276 ophil activation assays, and the presence of T-cell epitopes was determined based on lymphoproliferat

277 edicted peptide, distinct from the predicted T-cell epitope, was identified from ClpC.

278 Though the initial CD4 T cell epitopes were 15 amino acids in length, synthesis

279 s showed that, whereas the majority of human T cell epitopes were conserved in all sublineages, the p

280 n addition, five previously unidentified CD4 T cell epitopes were discovered, including epitopes in t

281 Herein, EBNA-1-specific T cell epitopes were evaluated after AdC-rhEBNA-1 immuni

282 ions of the PvCSP predicted to contain human T cell epitopes were genetically fused to an immunodomin

283 Six major Met e 1 T cell epitopes were identified.

284 le alpha3IV-NC1 domain, three immunodominant T cell epitopes were identified.

285 While PVM-specific CD8 T cell epitopes were recently described, so far no PVM-s

286 Five novel CD8 T cell epitopes were revealed within the RSV fusion (F)

287 Multiple Ana o 1 and Ana o 2 T cell epitopes were then identified.

288 servation of epitopes, low-level variants in T-cell epitopes were detected in 77.7% (14/18) of patien

289 Multiple Jug r 2 T-cell epitopes were identified.

290 B27 from three chlamydial proteins for which T-cell epitopes were predicted.

291 These conserved T cell epitopes, when combined with a cross-reactive ant

292 rt on the first VZV/HSV-1 cross-reactive CD4 T cell epitope, which is HLA-DR promiscuous and immunopr

293 ssays revealed that CCNB1 contained many CD4 T cell epitopes, which are differentially recognized by

294 us, immune responses can be augmented toward T cell epitopes with low functional avidity by increasin

295 epitope that we previously identified as CD4 T-cell epitope with increased binding to HLA-DQ8trans up

296 rived MHC class I and MHC class II candidate T-cell epitopes with potential antigen-specific cross-re

297 d 5 new CD8 T cell epitopes, including a CD8 T cell epitope within the G protein that was previously

298 potential to present a greater number of CD8 T cell epitopes within a single animal can delay immune

299 The T-cell epitope within AQP4 p61-80 was mapped to 63-76, w

300 ing peptides represent an important class of T cell epitopes, yet their prevalence remains underestim