ライフサイエンスコーパス: T-cell growth factor

1 ells and is thought to be the quintessential T cell growth factor.

2 d because IL-21 can substitute for IL-2 as a T cell growth factor.

3 Interleukin-2 (IL-2) is recognized as a T cell growth factor.

4 erleukin-2 (IL-2) is historically known as a T-cell growth factor.

5 ten require T cell costimulatory signals and T cell growth factors.

6 lity was largely reversed in the presence of T cell growth factors.

7 IL-2, the first cytokine discovered with T cell growth factor activity, is now known to have plei

8 IL-15 is a novel cytokine with potent T cell growth factor activity.

9 en applied to dendritic cells, UA suppressed T-cell growth factors but up-regulated B cell-activating

10 ) was initially characterized as the primary T-cell growth factor following in vitro activation, less

11 IL-15, a T cell growth factor, has been linked to exacerbating au

12 gnaling component by receptors for all known T cell growth factors (i.e., IL-2, IL-4, IL-7, IL-9, IL-

13 The T cell growth factor IL-2 has potential for expanding an

14 ts in a marked increase in production of the T cell growth factor IL-2, it does not result in a signi

15 ine leukemia virus-based vector encoding the T-cell growth factor IL-15.

16 CD8+ cells, is not regulated directly by the T-cell growth factors IL-2 or IL-15.

17 that p53 directly inhibits expression of the T cell growth factor (IL-2) in activated T cells.

18 Discovered as a T cell growth factor, IL-2 additionally promotes CD8(+)

19 roliferation and accumulation of the primary T cell growth factor, IL-2, by cells stimulated with ant

20 ence that diminished production of the major T cell growth factors, IL-2 and IL-4, is responsible for

21 ells of other established IFN-gamma inducing T-cell growth factors, IL-2, and IL-12 in this culture s

22 IL-2 is a critical T cell growth factor in vitro, but predominantly mediate

23 inetic experiments showed that both of these T cell growth factors induce a distinct and sustained ph

24 luding expression of the autocrine/paracrine T cell growth factor interleukin (IL)-2.

25 Expression of the gene is enhanced by the T cell growth factor interleukin-2, suggesting a role fo

26 actors are known to induce the expression of T-cell growth factor interleukin (IL)-2, it is unclear h

27 Stimulation via the T-cell growth factor interleukin 2 (IL-2) leads to tyros

28 in vitro by exposure to the same TA and the T-cell growth factor interleukin 2 (IL-2).

29 RyR down-regulated T cell proliferation and T-cell growth factor interleukin 2 production.

30 r nanoparticles containing magnetite and the T-cell growth factor interleukin-2 (IL-2).

31 ssociated with a defect in production of the T-cell growth factor interleukin-2 (IL-2).

32 Coexpression of the T-cell growth factor interleukin-2, however, greatly exp

33 d leads to increased production of the major T-cell growth factor, interleukin (IL)-2.

34 Hence coexpression of a T-cell chemokine and T-cell growth factor potentiates antitumor responses in

35 AIL, Itch and Nedd4 each negatively regulate T cell growth factor production and proliferation.

36 Interleukin-2 is the primary T cell growth factor secreted by activated T cells.

37 tial signaling component shared by all known T cell growth factor (TCGF) receptors (i.e., IL-2, IL-4,

38 IL-15 is a powerful T cell growth factor (TCGF) with particular importance f

39 T cell growth factors (TCGFs) play a critical role in al

40 ain (gamma(c)) that is activated by multiple T-cell growth factors (TCGFs) such as IL-2, -4, and -7.

41 kin (IL)-2, IL-4, IL-7, IL-9, and IL-15, all T-cell growth factors (TCGFs), utilize the common IL-2 r

42 IL-2 is a known potent T cell growth factor that amplifies lymphocyte responses

43 IL-2 is a T cell growth factor that has pleiotropic functions in T

44 IL-15 is a T cell growth factor that shares many biological activit

45 IL-15 is a proinflammatory and antiapoptotic T-cell growth factor that plays an important role in a v

46 We investigated the ability of IL-15, a T cell growth factor, to modulate prenyl phosphate-induc

47 s suggest that there could be a hierarchy of T-cell growth factors with regard to their ability to bl