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   1 (prostate), MDA-MB-231 (breast), and Jurkat (T-cell leukemia).                                       
     2  a spectrum of human malignancies, including T cell leukemia.                                        
     3 d retroviruses with the former causing adult T cell leukemia.                                        
     4 pathy/tropical spastic paraparesis and adult T cell leukemia.                                        
     5 ons in both the induction and maintenance of T cell leukemia.                                        
     6  perturbation of its activity often leads to T cell leukemia.                                        
     7  and MAPK kinase activities in CD3-activated T cell leukemia.                                        
     8 ll lines and dampens global transcription in T cell leukemia.                                        
     9 ackfan anemia (DBA), congenital asplenia and T cell leukemia.                                        
    10  of thymocytes, and subsequent generation of T-cell leukemia.                                        
    11 ors was associated with improved outcomes in T-cell leukemia.                                        
    12 e 1 (HTLV-1) is the causative agent of adult T-cell leukemia.                                        
    13  humans and is etiologically linked to adult T-cell leukemia.                                        
    14 cell transformation and development of adult T-cell leukemia.                                        
    15 event in the process of ZNF198-FGFR1-induced T-cell leukemia.                                        
    16 irus type-1 is the causative agent for adult T-cell leukemia.                                        
    17 nt of the aggressive and fatal disease adult T-cell leukemia.                                        
    18 1 (HTLV-1) is the etiological agent of adult T-cell leukemia.                                        
    19  infects CD4+ T lymphocytes and causes adult T-cell leukemia.                                        
    20 rus may play a role in the etiology of adult T-cell leukemia.                                        
    21 I (HTLV-1) is the etiological agent of adult T-cell leukemia.                                        
    22 onses in the majority of patients with adult T-cell leukemia.                                        
    23  1 (HTLV-1) is the etiologic agent for adult T-cell leukemia.                                        
    24  investigate the role of this interaction in T-cell leukemia.                                        
    25 ed ribosomal mutation in acute lymphoblastic T-cell leukemia.                                        
    26 y reduced in CD19(+) spleen B cells from Emu-T cell leukemia 1 (TCL1) transgenic mice relative to the
    27 tudies revealed that ROR1 could complex with T-cell leukemia 1 (TCL1) in CLL, we crossed these animal
  
  
  
  
  
    33 ogenesis related to the progression of adult T cell leukemia and HTLV-1-associated myelopathy/tropica
  
    35 ic virus type 1 (HTLV-1) mainly causes adult T cell leukemia and predominantly immortalizes/transform
    36 genetic aberrations that promote acute B and T cell leukemias and the mechanisms of cell transformati
  
  
    39 e 1 (HTLV-1) is the causative agent of adult T-cell leukemia and HTLV-1-associated myelopathy/tropica
    40 virus type 1 (HTLV-1) infection causes adult T-cell leukemia and is associated with a variety of lymp
    41  mature lymphocytes, develop multiple B- and T-cell leukemia and lymphoma subtypes, supporting an onc
    42 -1), an etiological factor that causes adult T-cell leukemia and lymphoma, has a crucial role in init
  
  
  
    46 virus type 1 (HTLV-1) infection causes adult T-cell leukemia and several lymphocyte-mediated inflamma
    47 kemia virus type 1 (HTLV-1)-associated adult T-cell leukemia and T-cell lymphoma (ATL) are aggressive
    48 with several serious diseases, such as adult T-cell leukemia and tropical spastic paraparesis/myelopa
    49 ry tumor virus (MMTV) variant, often induces T-cell leukemias and lymphomas by c-myc activation follo
    50 est that FBW7 is a novel tumor suppressor in T cell leukemia, and implicate the loss of FBW7 function
  
    52 and constitutive Notch signaling potentiates T cell leukemia as well as Drosophila neuroblast tumors.
  
  
    55 of pathologic abnormalities, including adult T cell leukemia (ATL) and HTLV-1-associated myelopathy/t
  
  
  
    59 1 (HTLV-1) is the etiological agent of adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/t
    60 e 1 (HTLV-1) is the causative agent of adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/t
  
    62 s-1 (HTLV-I) is the etiologic agent of adult T-cell leukemia (ATL) and the neurological disorder HTLV
    63 oup that first identified a cluster of adult T-cell leukemia (ATL) cases in Japan, provided conclusiv
    64 -1)-transformed lymphocyte cell lines, adult T-cell leukemia (ATL) cells, and in other hematologic ma
  
  
  
  
  
  
  
    72 s are implicated in the development of adult T-cell leukemia (ATL), a T-cell malignancy caused by HTL
    73 rus type 1 (HTLV-I) is associated with adult T-cell leukemia (ATL), an aggressive lymphoproliferative
    74 e-I (HTLV-I) is the etiologic agent of adult T-cell leukemia (ATL), an aggressive lymphoproliferative
    75 irus type 1 (HTLV-1) that recapitulate adult T-cell leukemia (ATL)-like leukemic symptoms and display
  
  
  
  
  
  
  
  
    84 distinct signaling proteins in a panel of 13 T-cell leukemia cell lines treated with a gamma-secretas
  
  
    87 GBP with selective cytotoxicity toward human T-cell leukemia cells and indicate its potential use in 
    88 zomib (an agent whose cytotoxicity in Jurkat T-cell leukemia cells is dependent on Noxa) was examined
    89 ol for the incubation of Jurkat (human acute T-cell leukemia) cells with Ac5ManNTGc and the quantitat
    90 ked to a spectrum of diverse diseases: adult T cell leukemia, encephalomyelopathy, and predisposition
    91 tudies, performed in translational models of T cell leukemia, establish a mechanism-based rationale f
    92 HTLV) type 1, the etiological agent of adult T-cell leukemia, expresses the viral oncoprotein Tax1.  
  
  
    95  oncogene (encoding the transcription factor T cell leukemia homeobox protein-1) has a major role in 
    96 n proposed to have tumor suppressor roles in T-cell leukemia homeobox 1/3-transformed human T-ALL cel
    97 NA binding site for the poorly characterized T-cell leukemia homeobox 3 (TLX3) TF was confirmed with 
  
  
  
   101 ell leukemia virus 1 (HTLV-1)-mediated adult T cell leukemia is associated with the ability of viral 
   102 ood, Nagai et al provide evidence that adult T-cell leukemia is hierarchically organized and sustaine
   103 leukemia virus type 1 (HTLV-1)-induced adult T-cell leukemia is linked to the expression of the viral
   104 lective and potent cytotoxicity toward human T-cell leukemia Jurkat cells compared with a panel of ca
  
  
   107 , pTa, Gata3, and Runx1, in both Ikaros null T cell leukemia lines and Ikaros null primary thymocytes
  
  
  
  
   112 kemia virus type 1 (HTLV-1)-associated adult T cell leukemia/lymphoma (ATL) cells as a model system. 
  
  
  
  
   117 ype 1 (HTLV-1) is a causative agent of adult T cell leukemia/lymphoma and a variety of inflammatory d
  
  
   120 virus type 1 (HTLV-1) infection causes adult T-cell leukemia/lymphoma (ATL) and is associated with a 
   121 d with the lymphoproliferative disease adult T-cell leukemia/lymphoma (ATL) and the neurodegenerative
  
  
  
   125 -cell leukemia virus type 1-associated adult T-cell leukemia/lymphoma (ATL) typically has survivals m
   126 sactivator initiates transformation in adult T-cell leukemia/lymphoma (ATL), a highly aggressive chem
   127 e 1 (HTLV-1) is the causative agent of adult T-cell leukemia/lymphoma (ATL), a malignancy of CD4(+) T
  
   129 leukemia (3), hairy cell leukemia (1), adult T-cell leukemia/lymphoma (ATLL) (1), marginal zone leuke
   130 ), anaplastic large-cell lymphoma, and adult T-cell leukemia/lymphoma (ATLL) and a lower incidence of
   131 r A (RHOA) hotspot mutations among the adult T-cell leukemia/lymphoma (ATLL) category have opposite b
  
  
   134 ic virus type-1 (HTLV-1) that initiate adult T-cell leukemia/lymphoma (ATLL) remain unclear, in part 
   135 We recently reported the first case of adult T-cell leukemia/lymphoma (ATLL) that responded rapidly t
   136  CD8(+) T cells, yet this virus causes adult T-cell leukemia/lymphoma (ATLL) that typically has a CD4
  
  
  
   140 ouse studies indicate that activation of the T-cell leukemia/lymphoma 1 (TCL1) oncogene is a contribu
   141 mmon human leukemia and dysregulation of the T-cell leukemia/lymphoma 1 (TCL1) oncogene is a contribu
  
  
  
   145 ive anaplastic large cell lymphoma, 14 adult T-cell leukemia/lymphoma and 44 extranodal NK/T-cell lym
   146 e 1 (HTLV-1) is the causative agent of adult T-cell leukemia/lymphoma and HTLV-1-associated myelopath
   147 causes two distinct pathologies termed adult T-cell leukemia/lymphoma and tropical spastic paraparesi
   148  virus type 1 (HTLV-1) is the cause of adult T-cell leukemia/lymphoma as well as tropical spastic par
   149    To study the impact of oncogenic K-Ras on T-cell leukemia/lymphoma development and progression, we
  
  
  
  
  
  
  
  
   158 1 (HTLV-1) is the etiological agent of adult T-cell leukemia/lymphoma, and it encodes a number of non
   159 l lymphoma, cutaneous T-cell lymphoma, adult T-cell leukemia/lymphoma, and other peripheral T-cell ly
   160 ided highly diverse results on the issues of T-cell leukemia/lymphoma-initiating cells (T-LICs) and p
  
  
  
  
  
  
   167 ferent human cancers including lymphoblastic T-cell leukemia, pancreatic cancer, melanoma and rhabdom
  
  
   170      Adult patients with acute lymphoblastic T cell leukemia (T-ALL) have a very poor prognosis and f
   171 nsmembrane protein highly expressed in acute T-cell leukemia (T-ALL) and in a subset of peripheral T-
   172 ly in primary and secondary tissues, we used T-cell leukemia (TCL)1 cells reactive with the autoantig
  
  
  
  
  
  
  
  
  
  
  
  
   185 ced apoptosis, we used TRAIL-resistant human T cell leukemia virus type 1 (HTLV-1)-associated adult T
   186 cytes) to the total viral burden in 22 human T cell leukemia virus type 1 (HTLV-1)-infected individua
  
  
   189    Furthermore, the Tax oncoprotein of human T cell leukemia virus type I targeted this complex for i
   190 l virus, human immunodeficiency virus, human T cell leukemia virus, human papilloma virus, hepatitis 
  
   192 recognizes the foreign Ag Tax from the human T cell leukemia virus-1 when presented by the class I MH
   193 sible link with the autoimmune disease human T cell leukemia virus-1-associated myelopathy/tropical s
  
  
  
   197 ly discovered the antisense protein of human T-cell leukemia virus (HTLV) type 2 (APH-2), whose messe
   198 ntification of the genes necessary for human T-cell leukemia virus (HTLV-1) persistence in humans may
  
   200 cation and partial characterization of human T-cell leukemia virus (HTLV; now known as HTLV-1) produc
  
  
  
  
  
  
   207 ence techniques in real time with both human T-cell leukemia virus type 1 (HTLV-1) and human immunode
  
  
  
   211  et al report that vaccination against human T-cell leukemia virus type 1 (HTLV-1) basic leucine zipp
  
   213 ally integrated form of the retrovirus human T-cell leukemia virus type 1 (HTLV-1) contains identical
   214 rs proposed a model for this region of human T-cell leukemia virus type 1 (HTLV-1) Env in which expul
  
   216 iculoendotheliosis virus A (REV-A) and human T-cell leukemia virus type 1 (HTLV-1) exhibit PCE activi
   217 nt data showing that neither HIV-1 nor human T-cell leukemia virus type 1 (HTLV-1) expresses signific
  
   219 PPY motif in the matrix (MA) domain of human T-cell leukemia virus type 1 (HTLV-1) Gag associates wit
  
  
  
  
  
  
  
  
   228      Surprisingly, the NC protein from human T-cell leukemia virus type 1 (HTLV-1) is an extremely po
  
  
   231 ablished that cell-free infection with human T-cell leukemia virus type 1 (HTLV-1) is less efficient 
  
  
  
  
  
  
  
  
  
  
   242 d, Fujikawa et al demonstrate that the human T-cell leukemia virus type 1 (HTLV-1) oncoprotein Tax in
   243 In the present study, we show that the Human T-cell Leukemia Virus Type 1 (HTLV-1) oncoprotein Tax is
   244 uggested to be largely dispensable for human T-cell leukemia virus type 1 (HTLV-1) particle biogenesi
   245 ecently shown to bind and activate the human T-cell leukemia virus type 1 (HTLV-1) promoter at bases 
  
  
  
   249 -risk human papillomavirus (HPV) E6 or human T-cell leukemia virus type 1 (HTLV-1) Tax oncoproteins. 
   250 lishment of humanized mice infected by human T-cell leukemia virus type 1 (HTLV-1) that recapitulate 
  
  
   253    The retroviral oncoprotein Tax from human T-cell leukemia virus type 1 (HTLV-1), an etiological fa
   254 udy, we found that HBZ, encoded by the Human T-cell Leukemia Virus type 1 (HTLV-1), binds to multiple
   255 of the deltaretroviruses, for example, human T-cell leukemia virus type 1 (HTLV-1), have been evaluat
   256 , which can result from infection with human T-cell leukemia virus type 1 (HTLV-1), is associated wit
   257 infection by HIV-1, HIV-1Deltavif, and human T-cell leukemia virus type 1 (HTLV-1), while significant
  
  
  
  
  
  
  
  
   266 s level of BIC by up to 70% in EBV- or human T-cell leukemia virus type 1 (HTLV1)-transformed cell li
  
   268     The Tax oncoprotein encoded by the human T-cell leukemia virus type 1 plays a pivotal role in vir
  
   270     Unlike the resistance of HIV-1 and human T-cell leukemia virus type 1 to hA3G, the resistance of 
   271 ion of additional human tumor viruses--human T-cell leukemia virus type 1, hepatitis C virus, and Kap
  
  
  
   275  viruses in the transplant population: human T-cell leukemia virus type 1; hepatitis E virus; bocavir
  
  
  
  
  
  
  
  
   284 date tumor suppressor, is repressed in human T-cell leukemia virus type-1 (HTLV-1)-transformed lympho
  
  
   287 nduces a severe telomere shortening in human T-cell leukemia virus type-1-infected cells which signal
  
  
  
  
  
  
   294 omain are highly conserved among the primate T cell leukemia viruses, but this extension is absent in
  
   296 sease onset in murine models of Notch-driven T-cell leukemia, whether Dicer1-processed miRNAs are ess
   297 ted mAb by immunizing mice with Jurkat acute T cell leukemia, which binds ILT3.Fc to its membrane.   
   298 vating IKK, yet only HTLV-1 infection causes T cell leukemia, which correlates with persistent activa
  
  
  
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